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  • 1980-1984  (10)
  • 1
    Electronic Resource
    Electronic Resource
    In vitro inactivation of the neurotoxic action of β-bungarotoxin by the marine natural product, manoalide (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 864-865 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The irreversible neurotoxic action of β-bungarotoxin (β-BuTx) can be prevented by preincubation of the toxin with manoalide, a non-steroidal anti-inflammatory agent. Manoalide was also found to inactivate purified phospholipase A2 and thus prevent hydrolysis of phosphatidylcholine. PLA2 is a component found in several neurotoxic venoms and is also a rate limiting enzyme important in phospholipid metabolism and prostaglandin synthesis in man.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01951998
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    LIPID EXTRACTION CONDITIONS TO DIFFERENTIATE AMONG HARD RED WINTER WHEATS THAT VARY IN BREADMAKING (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 45 (1980), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Extractability of total, nonpolar, or polar lipids from five hard red winter (HRW) wheat flours increased linearly with extraction temperature. Any increases in amounts of total extracted lipids, by varying solvent or extraction temperature, were mainly due to increases in the extracted polar lipids. Proper selection of solvent and/or extraction temperature was of major importance for polar lipid extractability. Extractability of lipid-phosphorus increased with temperature more rapidly than extractability of lipid-galactose, and the effect of temperature on the extractability of lipid-galactose was more pronounced with Skellysolve B or benzene than with acetone or 2-propanol. The amounts of polar lipids extracted with 2-propanol by a shaker at 75°C or by a Soxhlet were the most effective in differentiating the HRW flours according to their mixing times. The ratio of nonpolar to polar lipids extracted with petroleum ether or Skellysolve B, which extract free lipids, or the galactose content of free lipids best differentiated the HRW flours according to loaf volume potential.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1980.tb06513.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Enzymes of Cerebral GABA Metabolism and Synaptosomal GABA Uptake in Acute Liver Failure in the Rabbit: Evidence for Decreased Cerebral GABA-Transaminase Activity (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 42 (1984), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Measurements of the activities of the two key enzymes in cerebral GABA metabolism—glutamate decarboxylase (GAD) and GABA-transaminase (GABA-T)—were performed in normal rabbits and in rabbits with hepatic encephalopathy due to galactosamine-induced liver failure. Furthermore the uptake of GABA by synaptosomes was studied. Hepatic encephalopathy was associated with a marked decrease in the activity of GAB A-T. This decrease in activity was already apparent in galactosamine-treated rabbits before the onset of hepatic encephalopathy. Sera and serum ultrafiltrates of rabbits with hepatic encephalopathy but not of normal rabbits or of rabbits with uremic encephalopathy were shown to inhibit GABA-T activity in vitro. Cerebral GAD activity and synaptosomal GABA uptake in rabbits with hepatic encephalopathy and in untreated animals were not different. These later findings indicate that hepatic encephalopathy is not associated with alterations of presynaptic GABA nerve terminals in the central nervous system. The demonstration of a decrease in cortical GABA-T activity provides indirect evidence for decreased GABA turnover in the brains of rabbits with hepatic encephalopathy and thus is compatible with augmented GABA-ergic inhibitory neurotransmission contributing to the neural inhibition of hepatic encephalopathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1984.tb02816.x
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  • 4
    Electronic Resource
    Electronic Resource
    DIRECTIONAL SENSITIVITY OF INDIVIDUAL VERTEBRATE HAIR CELLS TO CONTROLLED DEFLECTION OF THEIR HAIR BUNDLES (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 374 (1981), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1981.tb30854.x
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  • 5
    Electronic Resource
    Electronic Resource
    Renal clearance of imipenem in children (1984)
    Springer
    European journal of clinical microbiology & infectious diseases 3 (1984), S. 471-474 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Imipenem renal clearance was studied in six children (three males, three females; 2.9–11.2 years of age) following a single intravenous dose (21.7±5.1 mg/kg) of imipenem/cilastatin (1∶1). In an approximately six-hour period following drug administration, 65.3±9.7% of the imipenem dose was excreted in the urine unchanged. The renal clearance (280.03±24.34 ml/min/1.73 m2) of imipenem was found to account for 69.2% of the corresponding plasma imipenem clearance (404.89±24.83 ml/min/1.73 m2). Contrary to existing adult data, the imipenem renal clearance in our subjects was 1.95-fold greater than the estimated creatinine clearance, suggesting significant tubular secretion of imipenem in children. Examination of urinary imipenem excretion rate versus plasma concentration relationships in three of the children revealed a potential renal tubular reabsorption component for imipenem in children. Comparison of renal imipenem clearance data in these children to similar data from adults suggests that quantitatively important developmental differences may exist for the renal handling of imipenem.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02017378
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Pythiaceous fungi associated with the decomposition of Nymphoides peltata (1982)
    Springer
    Antonie van Leeuwenhoek 48 (1982), S. 433-445 
    Details
    ISSN: 1572-9699
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Selective isolation procedures were carried out on decaying leaves of Nymphoides peltata (Gmel.) O. Kuntze in order to study the pythiaceous fungi (Peronosporales) associated with the decomposition processes. In addition to Pythium marsipium Drechsler and P. pleroticum T. Ito, a number of Pythium species were isolated with filamentous non-swollen sporangia. Under special culture conditions (in water under a day/night rhythm) sexual reproductive structures of P. diclinum Tokunaga and P. apleroticum Tokunaga were also obtained. However, several isolates designated as Pythium ‘F’, remained sterile. Within this group three types could be distinguished according to their temperature-growth relationships. As the species recorded have been found very rarely and only one was represented in the CBS collection, detailed descriptions with short discussions are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00448415
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  • 7
    Electronic Resource
    Electronic Resource
    The genus Apodachlya (1982)
    Springer
    Antonie van Leeuwenhoek 48 (1982), S. 389-399 
    Details
    ISSN: 1572-9699
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The genus Apodachlya Pringsheim is revised and restricted to three species, of which descriptions and illustrations are given. On the basis of a study of pure cultures, it is concluded that A. punctata Minden is identical with A. brachynema (Hildebrand) Pringsheim.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00418292
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of the “Amoco Cadiz ” oil spill on an eelgrass community at roscoff (france) with special reference to the mobile benthic fauna (1980)
    Springer
    Helgoland marine research 33 (1980), S. 182-191 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In October 1977 an investigation was initiated of the qualitative and quantitative composition of the fauna of the eelgrass (Zostera marina) beds at Roscoff. Samples were taken in 2 seagrass beds at different tidal levels in order to follow numerical changes in the course of the year. In March 1978 the area of study was struck by the oil slick of the tanker “Amoco Cadiz ”. For this reason sampling has been continued at the same frequency. The tabulated results show clearly that the oil slick had a profound but selective influence on the various animal groups; some of them disappeared while others were apparently unaffected. Rapid recovery of some species has taken place, but re-establishment of other species, particularly the filter feeders has not been observed. The very diverse amphipod fauna has disappeared, and has been replaced by a population ofPherusa fucicola andGammarus locusta; the latter was absent in the year before the oil disaster took place.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02414745
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  • 9
    Electronic Resource
    Electronic Resource
    Biomechanical analyses of some instrumentations for stabilisation of dorso-lumbar spinal injuries (1983)
    Springer
    Medical & biological engineering & computing 21 (1983), S. 494-502 
    Details
    ISSN: 1741-0444
    Keywords: Biomechanics ; Fixation device ; Spinal fracture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Quantitative biomechanical analyses of approaches for the reduction and fixation of lumbardorsal injury are presented in this paper, entailing (i) classification of the types of injuries, (ii) analysis of the critical functional levels of forces exerted on the injured spinal structures and the stabilisation devices and (iii) the basis for the various modalities of injury reduction stabilisation modes, and for the use of conventional posteriorly attached compression or distraction devices, as well as anteriorly placed vertebral stabilisation-fixation device.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442639
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Photo-Oxidation and photo-stabilization of blends of low-density polyethylene and styrene-butadiene-styrene copolymersPresented at the Symposium Polymer Blends, University of Warwick, September 1981. (1982)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 22 (1982), S. 912-916 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The photo-oxidation of blends of low-density polyethylene and styrene-butadiene-styrene block copolymers has, been shown to result mainly from the degradation of the pollybutadiene part of the material. The solution infra-red and fluorescence spectra, and mechanical properties have been studied as a function of the irradiation time. Evidence of some interaction between the components of the blend could be obtained.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760221410
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