Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1990-1994  (2)
  • 1975-1979  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Stimulation of partial development of human mast cells by supernatant fluid from mouse fibroblast cultures (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 24 (1994), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Fibroblasts have been implicated as culture-competent cells for the mast cell lineage in several species. In man, fibroblast monolayers sustain the ultrastructural phenotype and function of isolated human lung mast cells and permit the differentiation and full maturation of human mast cells from their agranular precursors in cord blood cells. We examined whether development and maturation of the mast cell lineage in man can be achieved by a supply of the soluble products present in fibroblast culture supernatants. Suspension cultures of cord blood cells were supplemented with culture supernatants derived from two different murine fibroblast lines; controls were not supplemented. The cultures were sampled for light and electron microscopy at 6, 7 and 8 weeks. Human mast cells developed in quantity when cultures were supplemented with the supernatants from BALB/c 3T3 fibroblasts, in reduced numbers when supplemented with Swiss Albino 3T3 fibroblast supernatants, and not at all in culture media alone. By ultrastructural criteria, the newly developed mast cells did not achieve full maturity; they did continue to synthesize new granules and to undergo intragranular maturational events. Small numbers of mature basophils persisted in suspension cultures, and many were undergoing piecemeal degranulation. Other cell lineages noted included eosinophils, neutrophils, macrophages and endothelial cells. We conclude that a factor(s) of fibroblast origin permits the differentiation and partial maturation of human mast cells from their agranular precursors in cord blood, but that fibroblasts must be physically present for complete maturation of these lineages to occur.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1994.tb00969.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Clinical features of 22 cases with “Inter-Sterno-Costo-Clavicular Ossification” (1979)
    Springer
    Archives of orthopaedic and trauma surgery 95 (1979), S. 13-22 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über 22 Fälle von “InterSterno-Costo-Clavikulärer Ossifikation” berichtet. Die klinischen und pathologisch-anatomischen Befunde zeigen, daß die abnorme Ossifikation durch tine nichteitrige, chronische Entzündung im Bereiche der Sterno-Costo-Clavikular-Region und des costo-clavikulären Ligamentes hervorgerufen wird. Wir klassifizieren die Röntgenbefunde in 3 Stadien, entsprechend dem Grad der Verknöcherung: lokalisiert, generalisiert und hyperostotisch. In dieser Reihenfolge schreitet auch die Erkrankung fort. Eine betrdchtliche Zahl der Patienten zeigten auch abnorme Röntgenbefunde an der Wirbelsäule oder den Sacroiliacalgelenken. Eine häufige Begleiterscheinung der Erkrankung war auch eine Pustolosis palmaris et plantaris. Die meisten Fälle wurden erfolgreich mit entzündungshemmenden Medikamenten behandelt; bei einigen Patienten wurde eine Besserung der Beschwerden erst nach chirurgischer Entfernung der verknöcherten Masse, einschließlich Clavikula oder 1. Rippe, erzielt.
    Notes: Summary We present 22 cases with inter-sterno-costoclavicular ossification. Clinical and pathological findings show that abnormal ossification observed in this situation is due to non-suppurative chronic inflammation of the soft tissues around the sterno-costo-clavicular region such as the costo-clavicular ligament. We have classified X-ray findings into three stages according to the extent of the ossification; localized, generalized, and hyperostotic, and show that the disease progressed in this sequence. A considerable number of the patients showed abnormal X-ray findings in the spine or the sacro-iliac joint. Frequent association of pustulosis palmaris et plantaris was noted in this disease. Most of the cases were treated effectively with anti-inflammatory drugs, but a few cases required surgical resection of the ossified mass with the clavicle or the first rib in order to relieve the severe pain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00379164
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Juvenile ankylosing spondylitis, its clinical features and HLA-B27 (1977)
    Springer
    Archives of orthopaedic and trauma surgery 87 (1977), S. 31-37 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 6 jugendliche Patienten mit ankylosierender Spondylitis werden untersucht. Die klinischen Beschwerden bestanden hauptsächlich in einer Polyarthralgie bzw. Coxalgie, aber ohne Schmerzen und Einsteifung im Bereich der Lendenwirbelsäule. Diese klinischen Bilder waren atypisch für ankylosierende Spondylitis und wiesen eher auf eine periphere Arthropathie im Sinne einer juvenilen rheumatoiden Arthritis hin. Nach langfristiger Beobachtung ergaben sich jedoch bei all diesen Patienten eindeutige Hinweise auf ankylosierende Spondylitis. Die HLA-B27 Antigene waren in 4 von 6 Fällen positiv. Diese Häufigkeit entspricht in etwa der bei den Erwachsenen ankylosierenden Spondylitis. HLA-Bestimmung erscheint daher für die Frühdiagnose sehr wichtig.
    Notes: Summary We have experienced six patients of juvenile ankylosing spondylitis. Their chief complaints were polyarthralgia or coxalgia, however, any pain or stiffness in lumbar regions was absent. These clinical features were atypical for those of ankylosing spondylitis, and much more like those of a peripheral arthropathy such as juvenile rheumatoid arthritis. After a long-term follow-up, all the patients showed definite clinical features of ankylosing spondylitis. HLA-B27 was found in 4 out of 6 cases. This frequency is almost equal to that of adult ankylosing spondylitis patients. HLA typing was very important in the early diagnosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00416137
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Ankylosing spinal hyperostosis (ASH) and ossification of the posterior longitudinal ligament (OPLL) (1979)
    Springer
    Archives of orthopaedic and trauma surgery 94 (1979), S. 21-23 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir berichten über die klinischen und röntgenologischen Krankheitsbilder der ankylosierenden Hyperostose der Wirbelsäule bei 70 Fällen. Rückenschmerzen in verschiedenen Bereichen wurden bei 49 Fällen beobachtet. HLA-Bestimmungen zeigten keine signifikanten Abweichungen. Röntgenologisch chrakteristische Befunde waren Osteophytenbzw. Brückenbildungen der Brustwirbelsäule, die auf dem rechten und vorderen Ted des Wirbelkörpers, besonders im kaudalen Anteil auffällig zu erkennen waren. Verknöcherung des hinteren Längsbandes wurde bei 21 Fällen beobachtet.
    Notes: Summary The clinical and radiological features of 70 patients with ankylosing spinal hyperostosis are presented. Pain in some region of the back was found in 49 patients. No significant deviations were found in HLA typing. Radiologically, the most characteristic features were bony spurs or bridges in the dorsal spine, where they predominated on the right and anterior aspects of the spine, especially in the lower dorsal region. Ossification of the posterior longitudinal ligament was found in 21 patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00448088
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Beschleunigung der Vernetzung von Polyäthylen durch γ-Strahlen mit Acetylen (1976)
    Springer
    Colloid & polymer science 254 (1976), S. 767-767 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01643910
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Identification of a gene family (kat) encoding kinesin-like proteins in Arabidopsis thaliana and the characterization of secondary structure of KatA (1993)
    Springer
    Molecular genetics and genomics 238 (1993), S. 362-368 
    Details
    ISSN: 1617-4623
    Keywords: Kinesin-related gene ; Gene family ; Arabidopsis thaliana ; Nucleotide sequence ; Secondary structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A gene family, designated kat, has been characterized in Arabidopsis thaliana by genomic Southern hybridization and nucleotide sequencing analysis. The kat gene family includes at least five members, named katA, katB, katC, katD and katE, whose products share appreciable sequence similarities in their presumptive ATP-binding and microtubule-binding motifs with known kinesin-like proteins. The carboxyl-terminal region of the KatA protein deduced from the nucleotide sequence of the cDNA clone has considerable homology with the mechanochemical motor domain of the kinesin heavy chain. The predicted secondary structure of the KatA protein indicates two globular domains separated by a long a helical coiled coil with heptad repeat structures, such as are commonly found in kinesin-like proteins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00291995
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...