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  • 1990-1994  (2)
  • 1970-1974  (1)
  • 1955-1959  (2)
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  • 1
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: One hundred children who presented for minor general surgical procedures were randomly assigned to receive one of two oral premedications. Those in group A (n = 50) were given 3 mg/kg of trimeprazine and those in group B (n = 50) a mixture of trimeprazine 1.0 mg/kg, droperidol 0.15 mg/kg and methadone 0.08 mg/kg. Patients in group B were more likely to be asleep on arrival in the anaesthetic room (p 〈 0.02) and were less likely to be distressed at induction of anaesthesia (p 〈 0.02). Thiopentone requirements were less in group B (p 〈 0.001). The incidence of side effects was similar in the two groups. It is concluded that the mixture produces more satisfactory sedation than trimeprazine.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 44 (1957), S. 554-555 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 165 (1970), S. 163-173 
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung 1. Die Entwicklung der Cholinesterase-Aktivität im axialen Mesoderm vonTriturus cristatus von der Neurula bis zur schwimmenden Larve mit zwei Zehen (Harrison-Stadium 15–42) wurde histochemisch untersucht. 2. Nach Einbettung der Keime in Polyäthylenglykol wurde der ChE-Nachweis an Serienschnitten nach Karnovsky und Roots (nach Blockierung der Sulfhydrylgruppen mit Maleinimid) und mit der Koelle-Methode durchgeführt. 3. Im Stadium der offenen Neurula konnte die ChE im Urdarmdach im präsumptiven Chorda- und Somitenmaterial nachgewiesen werden. 4. Die Chorda ist vom späten Neurula- bis zum mittleren Schwanzknospenstadium (Harrison-Stadium 25) in ihrer ganzen Länge ChE-positiv. Anschließend verschwindet die ChE-Aktivität von cranial nach caudal fortschreitend aus der Chorda. 5. Die Hypochorda zeigt vom Beginn ihres Auftretens im Harrison-Stadium 21/22 an eine außerordentlich starke ChE-Aktivität, die sich im Stadium 30–33 wieder verliert. Bald darauf läßt sich die Hypochorda histologisch nicht mehr erkennen. 6. Die einzelnen Somiten sind bei ihrer Entstehung ChE-positiv. 7. Mit der cranial einsetzenden Ausbildung der Myotome steigt die ChE-Aktivität in den beteiligten Somitenzellen stark an. Zu diesem Zeitpunkt (Harrison-Stadium 24–26) sind caudal regelmäßig ChE-negative Somiten anzutreffen. Mit ihrer Umwandlung in Myotome tritt in ihnen wieder eine ChE-Aktivität auf. Sie setzt am dorsomedialen Somitenrand ein. 8. Die ChE-Aktivität in den Myoblasten erstreckt sich zunächst über die gesamte Zelle. Vom Harrison-Stadium 35 an konzentriert sie sich an den Enden der Myoblasten im Bereich der Segmentgrenzen. Gleichzeitig mit der starken Aktivität in den Myoblasten tritt eine ChE-Aktivität in den motorischen Vorderhornzellen im Neuralrohr auf.
    Notes: Summary 1. InTriturus cristatus embryos (Harrison stages 15–42) the development of cholinesterase (ChE) activity in the axial mesoderm was investigated. 2. After embedding in polyethylene glycol the histochemical technique of Karnovsky and Roots (preincubation in maleinimid to block sulfhydryl groups) and that of Koelle were employed on serial sections. 3. In early neurula stage ChE is found in the presumptive notochordal and somite material of the archenteron roof. 4. The notochord is ChE-positive from late neurula stage until Harrison stage 25. Then the cells loose their activity in cranio-caudal progression. 5. The subnotochordal rod is ChE-positive from Harrison stage 21/22 until Harrison stage 30–33. 6. The somites are ChE-positive as they develop. 7. During the formation of myotomes, beginning in the cranial part of the embryo the amount of ChE in the engaged somite cells increases. At this time (Harrison 24–26) ChE-negative somites are found in the caudal part of the embryo. These somites become ChE-positive before they change into myotomes. 8. From the beginning the whole myoblasts are ChE-positive. Beginning with Harrison stage 35 the activity concentrates at the ends of the myoblasts near the segmental border. At this time a strong activity in the motor cells of the neural tube appears.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 90 (1959), S. 524-525 
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Lactic acid and short-chain carboxylic acids C1-C5 were analyzed on an Aminex HPX-87H column using UV and RI detection. The HPLC method was applied to complex fermentation media of a microbial lactic acid formation process. The resulting chromatograms of the yeast extract or culture medium showed some UV-absorbing substances that interfered partially with peaks of short-chain carboxylic acids.In contrast to UV monitoring, RI detection gave only a few small peaks of these so-called “background chromatograms”. Also glucose used as substrate could be quantified in the culture medium, because of which RI detection should be preferred.Furthermore, a self-prepared cation-exchange resin (SAC = S-DVB) based on a poly(styrenedivinylbenzene) partially comparable in its properties with Aminex resins was useful for fast (about 4 minutes) and not too expensive determinations of lactic and acetic acid in fermentation media.Applying this separattion system to fermentation solutions detected by RI as well as UV monitoring results in the quantitative analysis of lactic acid kinetics identical with an Aminex HPX-87H column were achieved.Finally, the simplicity of lactic-acid analysis is illustrated by examples of dairy products only centrifugated and diluted in double distilled water before injecting on a cation-exchange column.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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