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  • 1970-1974  (6)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 5 (1970), S. 16-23 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Conclusions 1) Measurements of serum DDT concentration are capable of relfecting changes in oral DDT intake accurately and promptly. 2) Serum DDE level is only slightly increased by a 300–600 fold increase in DDT intake over a period of 5 months. It is therefore an essentially worthless measure of recent change in oral DDT intake. Stable individual differences in serum DDE levels, seemingly much wider than differences in dietary patterns (i.e. DDE intake), suggest the importance of individual metabolic factors in determining this level. 3) A high degree of correlation between serum DDT and DDE in day to day samples extracted once by hexane, probably reflects changes in extractability influencing the two measurements similarly.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 238 (1972), S. 221-223 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Hayes properly summarized existing knowledge of the excretability of DDT as "intermediate between that of most drugs and that of lead and other bone seekers"11. He also indicated that the rate of loss of fat-stored chlorinated hydrocarbons increases strikingly with the magnitude of store. Excretion ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 12 (1974), S. 547-554 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Conclusions 1. The liver excretes DDT and dieldrin into the bile. 2. The dieldrin content of bile from a worker having very high tissue stores is much greater than it is in persons with no occupational exposure. This suggests the existence of substrate-responsive excretory mechanisms. 3. We have tentatively identified the aldehyde degradation product of dieldrin in adipose fat, bile,and gall stone. The ketone product has not been found in fat, bile, or gall stone.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 8 (1972), S. 321-326 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Conclusions 1. Less than 18% of the pp'DDT and pp'DDE found in human blood is carried in the erythrocytes, while dieldrin is distributed between RBC and plasma roughly in proportion to volume. 2. In non-lactescent sera, chylomicra carry less than 1% of the total pesticide. Protein-free serum is virtually devoid of pesticide. 3. pp'DDT and pp'DDE are found in relation to lipoproteins of various densities, but principally in the triglyceride-rich low-density and very-low-density lipoproteins. 4. The plasma albumin, and secondarily the smaller globulins are the principal plasma protein constituents associated with blood-borne pp'DDT and pp'DDE.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract In each of two studies, two human volunteers entered methyl- or methyl-ethyl parathion-treated cotton fields for 30-minute periods at 0, 12, 24, 48, and 72 hours after treatment; foliage residues, and skin, clothing, inhalation, and biomedical data were obtained. The hands are probably the greatest source of absorbed pesticide chemical while the respiratory system is an insignificant source. Trousers collect the largest amounts of residue but the residue on them does not necessarily undergo absorption by the skin. There is not any evidence of plasma- or red-cell cholinesterase depression or a detectable amount ofpara-nitrophenol, following one-day, single, 30-min exposure. It is estimated that an individual can absorb up to 6.0 milligrams of parathion from cotton 24 hours after treatment with parathion and up to 3.0 milligrams 48 hours after such treatment, during an actual 5-hour work day field exposure. Skin-, and clothing contamination data are inadequate bases for evaluating hazard of possible parathion poisoning. Far more useful are measurements of serum parathion, serum-, and cell cholinesterase activities, and urinary excretion ofpara-nitrophenol in exposed individuals.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Four human volunteers entered Azodrin, methyl- or ethyl-parathion-treated cotton fields for 5-hour working periods 24-hours after treatment. Foliage residue levels, and skin, clothing, inhalation, and biomedical data were obtained. Foliage residues indicated Azodrin〉ethyl〉methyl parathion, with degrees of clothing and hand contamination, personal absorption and effect of blood ChE corresponding with relative foliage residue levels of the three insecticides. There was no effect on ChE from exposure to methyl parathion; however, Azodrin produced a drop in RBC ChE, while ethyl parathion resulted in a slight lowering of both RBC and plasma ChE. Dermal penetration was the principal route of pesticide absorption in this work situation.
    Type of Medium: Electronic Resource
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