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  • 1,25-(OH)2-D  (1)
  • Achlorophyllous alga  (1)
  • Breast carcinoma  (1)
  • Bromperidol; reduced brom- peridol  (1)
Datenquelle
Materialart
Erscheinungszeitraum
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Plasma 1,25-dihydroxyvitamin D concentrations in cords, newborns, infants, and children (1980)
    Springer
    Calcified tissue international 30 (1980), S. 1-3 
    Details
    ISSN: 1432-0827
    Schlagwort(e): 1,25-(OH)2-D ; Children ; Newborns
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Notizen: Summary Plasma 1,25-dihydroxyvitamin D [1,25-(OH)2-D] was measured in cord serum, newborns, infants, and children. The mean for the values obtained from the six cords was significantly higher than the mean for the older children (6–15 years). The mean for the six newborns (0–1 week) was significantly higher than that for the older children. The mean for the nine infants (1 week-6 months) and the 14 younger children (6 months-6 years) was significantly higher than that for older children. The present study suggests that the perinatal period is associated with a marked increase in 1,25-(OH)2-D.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02408599
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Interaction between carbamazepine and bromperidol (1997)
    Springer
    European journal of clinical pharmacology 52 (1997), S. 219-222 
    Details
    ISSN: 1432-1041
    Schlagwort(e): Key words Carbamazepine ; Bromperidol; reduced brom- peridol ; plasma concentration
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Abstract Objective: The interaction between carbamazepine and bromperidol was studied in 13 schizophrenic inpatients. Methods: Before carbamazepine addition, the subjects were taking bromperidol 12–24 mg · day−1 for 1–20 weeks. Carbamazepine 400 mg · day−1 was coadministered for 4 weeks, and blood samplings were performed before carbamazepine addition and at weekly intervals after the addition. Plasma concentrations of bromperidol and its reduced metabolite were measured by high-performance liquid chromatography. Results: Carbamazepine significantly decreased plasma concentrations of both bromperidol and reduced bromperidol for all weeks. On average, the plasma concentrations of bromperidol and reduced bromperidol at 4 weeks were 37% and 23% of the corresponding precarbamazepine values. Despite these decreases in plasma concentration, the Clinical Global Impression scores decreased slightly but significantly after carbamazepine addition. Conclusion: The present study suggests that carbamazepine decreases plasma concentrations of bromperidol and its reduced metabolite by inducing the metabolism of these compounds. Nevertheless, adjunctive carbamazepine may be useful for schizophrenic patients treated with bromperidol.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002280050277
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  • 3
    Digitale Medien
    Digitale Medien
    Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma (1995)
    Springer
    Virchows Archiv 426 (1995), S. 441-446 
    Details
    ISSN: 1432-2307
    Schlagwort(e): DCC gene ; Breast carcinoma ; Histopathology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Loss of heterozygosity (LOH) at the deleted in colorectal carcinoma gene (DCC), a tumour suppressor gene that encodes a protein with high homology to the neural cell adhesion molecule, was investigated in 42 surgical specimens of primary breast carcinoma. LOH was analysed in breast carcinoma by amplifying the DNA, spanning a variable number of tandem repeats site and a restriction fragment length polymorphism site within DCC, using the polymerase chain reaction (PCR). Cell sorting was used to enrich carcinoma cells. The expression of the DCC gene was also investigated using a reverse transcription-PCR method followed by Southern blot hybridization. LOH at the DCC locus was detected in 15 (51.7%) of 29 informative cases and 10 of 13 cases having DCC-LOH showed distinct reduction or loss of DCC expression. The DCC-LOH was closely associated with certain histological phenotypes; DCC-LOH was more frequent in scirrhous carcinomas than in solid-tubular ones (P〈0.05), and was also more frequent in carcinomas with infiltration into fat tissue over the mammary gland than in those without infiltration (P〈0.05). DCC-LOH was detected in invasive lobular carcinomas (2/2), but in none of the noninvasive ductal carcinomas (0/2). These observations suggest that malignant histological phenotypes are associated with DCC-LOH.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00193166
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  • 4
    Digitale Medien
    Digitale Medien
    Effects of some factors on protoplast formation of a microalga, Prototheca zopfii (1997)
    Springer
    World journal of microbiology and biotechnology 13 (1997), S. 355-356 
    Details
    ISSN: 1573-0972
    Schlagwort(e): Achlorophyllous alga ; enzymatic degradation ; protoplast formation ; Prototheca.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Abstract The effects of experimental factors on protoplast formation of Prototheca zopfii Kru¨ger in 0.85 m NaCl using Macerozyme R-200 were studied based on a fractional factorial experimental design. The rate of protoplast formation was mainly affected by the incubation temperature and the age of algal cells. The optimal condition for the maximum protoplast yield was determined based on a response surface model. These were: mid-logarithmic phase cells and Macerozyme concentration of 4% at a temperature of 35°C.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1018555628895
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