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  • 1
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Magnetresonanztomographie ; MRT ; Haut ; In-vivo-Histometrie ; Tumore ; Keywords MRT ; Skin ; Thickness ; Dermatology ; Tumors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: To characterize human skin qualitatively and quantitatively using high-resolution magnetic resonance tomography (MRT) and to compare skin thickness measurements from MRT and histological specimens. Material and Methods: The skin of 84 persons was examined by use of a 2.5 cm coil in a whole-body tomography (gradient field strength 1.5 T) at a linear resolution of 100 μm. To evaluate the ability to identify various skin structures, following an initial visual description, the signal-noise and contrast-noise ratios were analyzed and the MRT-image compared to the corresponding histological specimen. Results: Using the high-resolution coil, epidermis, dermis and subcutis were discernible. Problem areas included the cheek, distal leg and foot. Reproducible measuring of skin thickness with MRT is possible, but it does not correlate well with conventional histologic measurements.
    Notes: Zusammenfassung Ziel: Anhand von In-vivo-Untersuchungen war die Schnittbildanatomie der Haut hinsichtlich ihrer bislang unbekannten Erscheinung im hochauflösenden Magnetresonanztomogramm (MRT) zunächst qualitativ und quantitativ zu charakterisieren. Anschließend sollte der Wert der MRT hinsichtlich der Hautdickenmessung anhand eines Vergleiches mit histologischen Schnitten analysiert werden. Methodik: In einer prospektiven Studie wurde die Haut von 84 Personen mit Hilfe eines 2,5 cm großen Spulenkopfes in einem Ganzkörpertomographen (Gradientenfeldstärke: 1,5 T) bei einer linearen Auflösung von 100 μm untersucht. Zur Bewertung der Abgrenzbarkeit verschiedener Hautstrukturen wurden nach visueller Charakterisierung deren Signal-Rausch- und deren Kontrast-Rausch-Verhältnisse objektiviert und ein Vergleich mit histologischen Präparaten vorgenommen. Ergebnisse: Mit der Hochauflösungsspule lassen sich Epidermis, Dermis und Subkutis differenzieren (p〈0,05). Problematisch ist dies nur an Wange, distalem Unterschenkel und Fuß. Hautdickenmessungen mit der MRT sind zuverlässig möglich. Die Ergebnisse korrelieren aber nicht mit jenen der Histologie.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1352-8661
    Keywords: magnetic resonance imaging ; surface coils ; MR-imaging technology ; tissue characterization ; skin ; wrist ; finger ; Achilles tendon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics
    Notes: Abstract To investigate the application of a mini-coil surface system for high-resolution MRI, 60 volunteers were examined in a 1.5-T whole-body scanner. Two replaceable probe heads were available: a circular 2.5-cm coil and a quadratic 5-cm coil, both of which were placed directly on the skin. The skin layers, Achilles tendon and finger joints were examined with the 2.5-cm coil and a FOV of 25 × 25 mm2. A matrix of 256 × 256 pixels resulted in a pixel size of 0.098 × 0.098 mm2. For imaging of the carpal tunnel, the 5-cm coil was used in transverse orientation. The FOV was 50 × 50 mm2 so that a matrix of 256 × 256 pixels led to a pixel size of 0.195 × 0.195 mm2. The resulting spatial resolution permitted visualization of the epidermis, dermis and subcutis, resulting in clear definition of anatomical detail of the musculoskeletal system. MRI measurement of skin-layer thickness did not correlate with histometric data (p〈0.05). This discrepancy was due in part to shrinkage of the tumor specimen on histologic preparation. Other causes include the motion artifacts and the limited accuracy of determining thickness on the MRI display unit.
    Type of Medium: Electronic Resource
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