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  • 1
    ISSN: 1432-0533
    Keywords: Alzheimer's disease ; Dementia ; Aging ; Cortical capillaries ; Basement membrane ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Data concerning width and surface of the basement membrane of cortical capillaries in three patients with Alzheimer's disease five age-matched controls, have been submitted to statistical analysis to ascertain the role of the aging process upon thickening of the basement membrane itself. The analysis showed that there was a significant difference between patients with Alzheimer's disease and controls (P〈0.01) as to both width and surface of the basement membrane, so suggesting that in these patients aging was not the only factor which thickening of the basement membrane of cortical capillaries was related to.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1590-3478
    Keywords: Alzheimer's disease ; Creutzfeldt-Jakob ; Transmissible dementias
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Una grande quantità di neuroni in degenerazione neurofibrillare e di placche senili, fu trovata nella corteccia cerebrale di una donna di 52 anni affetta da una demenza ad evoluzione subacuta, mioclonie e alterazioni elettroencefalografiche periodiche. È questo un caso sporadico di demenza presenile di Alzheimer clinicamente sovrapponibile alla malattia di Creutzfeldt-Jakob, che si presta a ipotizzare un rapporto fra quella malattia e le demenze trasmissibili.
    Notes: Abstract Large numbers of neurofibrillary tangles and neuritic plaques were found in a cerebral biopsy from a 52-year-old woman suffering from subacute dementia with early myoclonus and quasiperiodic EEG changes. This case, which appeared to be an example of non-familial Alzheimer's disease, is commented in the context of possible relation of Alzheimer's disease to transmissible dementia.
    Type of Medium: Electronic Resource
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