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  • 1
    Electronic Resource
    Electronic Resource
    Ultrastructural basis for antigen mapping using sodium chloride-separated skin (1991)
    Springer
    Archives of dermatological research 283 (1991), S. 529-532 
    Details
    ISSN: 1432-069X
    Keywords: Blistering skin diseases ; Antigen mapping ; Split skin studies ; Anchoring filaments ; Subbasal dense plate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In many cases of autoimmune blistering skin diseases indirect immunofluorescence with serum of patients on 1 M NaCl-separated skin represents a rapid diagnostic tool before the use of more complicated immunoelectron microscopy. The present study demonstrates that in skin samples from five adults, separated using 1 M NaCl, 0.15 M NaCl and 0.01 M phosphate buffered saline (PBS), the split formed within the lamina lucida at an identical ultrastructural level. The sub-basal dense plate (SDP) with a wreath of anchoring filaments remained on the epidermal side of the split adjacent to the hemidesmosomal part of the plasma membrane of basal keratinocytes. The base of the split blister was constituted from the lamina densa, with a remote possibility of some anchoring filaments attached. We demonstrate that antigens on the roof of the NaCl- or PBS-split blister may be associated, beside intracellular hemidesmosomal structures, with the SDP and basement membrane components between the SDP and the basal keratinocytes as well as with anchoring filaments attached to the SDP. The observations reported here allow a more precise mapping of antigen determinants in blistering skin diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00371928
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Plötzlicher Tod bei Urticaria pigmentosa (1990)
    Springer
    International journal of legal medicine 103 (1990), S. 541-546 
    Details
    ISSN: 1437-1596
    Keywords: Urticaria pigmentosa ; Nettleship Syndrome ; Sudden death, anaphylactoid reaction ; Urticaria pigmentosa ; Nettleship-Syndrom ; plötzlicher Tod, anaphylaktoide Reaktion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wird über den plötzlichen Tod eines 25jährigen berichtet, bei dem seit 6 Jahren eine Urticaria pigmentosa bekannt war. Er wurde an einem kalten Novembermorgen auf dem taunassen Rasen tot aufgefunden. Histologisch fanden sich keine Anhaltspunkte für eine systemische Mastozytose. Die biochemischen Untersuchungen (stark erhöhter Histamin-Wert im Urin) erklärten zusammen mit der BAK von 0,72 ‰ und der Auffindesituation (Kältereiz) den tödlichen Pathomechanismus, eine generalisierte anaphylaktoide Reaktion.
    Notes: Summary A case of sudden death of a 25-year-old man, with a six years history of Urticaria pigmentosa, is reported. On a cold morning in November he was found lying dead on the lawn. Histology revealed no signs of systemic mastocytosis. The biochemical investigations (high free histamin level in urine) in addition to a BAC of 0,72 mg/g and the scene conditions (cold irritation) explained the mechanism of death, a systemic anaphylactoid reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01254407
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Plotzlicher Tod bei Urticaria pigmentosa (1990)
    Springer
    International journal of legal medicine 103 (1990), S. 541-546 
    Details
    ISSN: 1437-1596
    Keywords: Urticaria pigmentosa ; Nettleship Syndrome ; Sudden death, anaphylactoid reaction ; Urticaria pigmentosa ; Nettleship-Syndrom ; plötzlicher Tod, anaphylaktoide Reaktion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wird über den plötzlichen Tod eines 25jährigen berichtet, bei dem seit 6 Jahren eine Urticaria pigmentosa bekannt war. Er wurde an einem kalten Novembermorgen auf dem taunassen Rasen tot aufgefunden. Histologisch fanden sich keine Anhaltspunkte für eine systemische Mastozytose. Die biochemischen Untersuchungen (stark erhöhter Histamin-Wert im Urin) erklärten zusammen mit der BAK von 0,72ℵ und der Auffindesituation (Kältereiz) den todlichen Pathomechanismus, eine generalisierte anaphylaktoide Reaktion.
    Notes: Summary A case of sudden death of a 25-year-old man, with a six years history of Urticaria pigmentosa, is reported. On a cold morning in November he was found lying dead on the lawn. Histology revealed no signs of systemic mastocytosis. The biochemical investigations (high free histamin level in urine) in addition to a BAC of 0,72 mg/g and the scene conditions (cold irritation) explained the mechanism of death, a systemic anaphylactoid reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00209161
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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