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  • 1990-1994  (15)
  • Chemistry  (11)
  • pharmacokinetics  (4)
  • 1
    Digitale Medien
    Digitale Medien
    Pharmacokinetics and dosage regimen of cephalexin in buffalo calves (Bubalus bubalis) following single intravenous and intramuscular administration (1990)
    Springer
    Veterinary research communications 14 (1990), S. 59-62 
    Details
    ISSN: 1573-7446
    Schlagwort(e): buffalo ; cephalexin ; pharmacokinetics ; treatment
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00346385
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  • 2
    Digitale Medien
    Digitale Medien
    Interpenetrating polymer networks: A review on synthesis and properties (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 35 (1994), S. 109-118 
    Details
    ISSN: 0959-8103
    Schlagwort(e): Interpenetrating polymer networks ; synthesis ; properties ; mechanism ; structure-property relationship ; Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: A review containing 83 references on the chemistry aspects (mechanism and structure-property relationships) for IPN synthesis is presented.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pi.1994.210350201
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  • 3
    Digitale Medien
    Digitale Medien
    Spontaneous current emission in metal-ferrocene-doped ethyl cellulose-metal systems (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 35 (1994), S. 153-159 
    Details
    ISSN: 0959-8103
    Schlagwort(e): spontaneous current emission ; activation centres ; barrier polarization ; plasticization effect ; Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: Spontaneous current emission (SCE) has been studied in sandwiched different electrode configurations [metal(1)-undoped/doped ethyl cellulose (EC)-metal (1)/(2)] as a function of heating rate, film thickness and dopant concentration in the temperature range 40-200°C. The magnitude and direction of current depend on the combination of electrode metals. SCE thermograms for the Al undoped/doped EC-AI system exhibit two well resolved transition at 110 and 160°C in opposite directions to each other. The phenomena related to these transitions are explained in terms of creation of field at the interfaces and field produced in the bulk of the material. No negative direction transition was observed for electrode systems like Ag-Ag, Pb-Pb, Sn-Sn and Au-Au except for a shoulder of a peak around 100°C. When dissimilar electrode systems (i.e. Al-undoped/doped EC-Ag/Pb/Sn) are used, the current rises and then saturates beyond around 160°C.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pi.1994.210350205
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  • 4
    Digitale Medien
    Digitale Medien
    Copolymerization of zinc acrylate with acrylonitrile initiated by As2S3-styrene complex (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 34 (1994), S. 105-109 
    Details
    ISSN: 0959-8103
    Schlagwort(e): Zinc acrylate ; acrylonitrile ; As2S3-styrene complex ; copolymerization ; dilatometry ; kinetics ; Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: Radical copolymerization of zinc acrylate (ZnA2) with acrylonitrile (AN), initiated by As2S3-styrene complex(I), in dimethyl Sulphoxide (DMSO) at 90 ± 0.1°C for 1.0h under inert atmosphere, yields non-alternating copolymers. The kinetic expression is Rp ∝ [I]0.33 [ZnA2]0.25 [AN]0.44, i.e. the system follows non-ideal kinetics, which is due to primary radical termination as well as degradative chain transfer reactions. The values for activation energy (E) and k2p/kt are 128kJ mol-1 and 8.57 × 10-7 litre mol-1 s-1, respectively. Thermal stability, solubility in different solvents, and IR and NMR spectra have been evaluated.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pi.1994.210340114
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  • 5
    Digitale Medien
    Digitale Medien
    Synthesis of zinc-containing epoxy resin (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 51 (1994), S. 203-211 
    Details
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: Novel epoxy resins containing zinc acrylate have been synthesized by reacting zinc acrylate with bisphenol-A and an excess of epichlorohydrin. Parameters such as epoxy equivalent weight, hydroxyl content, and hydrolyzable chlorine content have been estimated. These resins, characterized by IR, 1H-NMR, and 13C-NMR, have been evaluated by thermal analysis. Curing was carried out with polyamide at 130°C for 24 h. Cured resins have improved thermal and chemical resistance. The reaction follows first-order kinetics with activation energy 86 and 34 kJ mol-1 in the presence and absence of zinc acrylate. The role of zinc, which increases epoxidation due to formation of complex with bisphenol-A, has been discussed. © 1994 John Wiley & Sons, Inc.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/app.1994.070510201
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  • 6
    Digitale Medien
    Digitale Medien
    Measurement and regulation of the culture reduction state in Clostridium acetobutylicum (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 38 (1991), S. 181-190 
    Details
    ISSN: 0006-3592
    Schlagwort(e): solventogenic metabolism ; NADH content ; NADH fluorescence ; continuous fermentation ; butanol biosynthesis ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: With a constant glucose feed concentration, the change in the continuous culture dillution rate resulted in an altered fermentation profile and the cellular NADH content. The cultures growing at high dillution rates demonstrated an oxidative metabolism low NADH and butanol concentrations. The low specific NADH flourescence (F/X) at high butanol production rates suggested that a rapid regeneration of NADH to NAD is essential for a high solventogenic culture activity. The culture florescence and butanol concentration remained constant in the solventogenic dilution rate range of D = 0.05-0.2 h-1 with an inverse relationship between the specific flourescence (F/X) and the specific butanol production rate, qB. Flourometric NADH observations were confirmed by enzymatic NADH determination. The stiochiometric “Fermentation Equation” was used to check the experimental data consistency and to investigate the role of the available biosynthetic and reduction energy on the culture metabolic activities under different growth conditions. The butanol concentration in the broth was stabilized in a fed-batch process when the culture NADH fluorescence was being controlled through the addition of fresh medium.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bit.260380210
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  • 7
    Digitale Medien
    Digitale Medien
    NADH fluorscence in a carbon-limited fermentation (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 38 (1991), S. 191-195 
    Details
    ISSN: 0006-3592
    Schlagwort(e): continuous flow acetone-butanol fermentations ; reduction energy ; solvent production activity ; inlet sugar concentrations ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The continuous flow acetone-butanol fermentation conducted at lowered inlet feed sugar concentrations and at a constant dilution rate D =0.075 h-1 demonstrated a significant decreases in the availability of the cell population “reduction energy” (F/X), resulting in an exclusive accumulation of intermediate acids under those conditions. The cultures resumed its solvent production activity when the inlet sugar concentration in the feed stream was increased from 20 to 40 g/L at the same low growth/dilution rates. A linear correlation between the culture reduction content (F/X) and the specific butanol rate (qB) was observed under the present conditions, indicating the necessity of the NADH availability for the increased solvent production.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bit.260380211
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  • 8
    Digitale Medien
    Digitale Medien
    Disposition kinetics, urinary excretion and dosage regimen of kanamycin in buffalo calves following single intravenous administration (1993)
    Springer
    Veterinary research communications 17 (1993), S. 219-225 
    Details
    ISSN: 1573-7446
    Schlagwort(e): buffalo ; disposition ; dose ; kanamycin ; pharmacokinetics ; serum ; urine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The disposition kinetics and appropriate dosage regimen for kanamycin were investigated in buffalo calves following a single intravenous dose of 10 mg/kg body weight. The distribution and elimination half-lives were 0.12±0.01 h and 1.94±0.11 h, respectively. The apparent volume of distribution and total body clearance were 0.2±0.01 L/kg and 92.9±3.69 ml/kg/h, respectively. About 74% of the administered dose was excreted in urine in 24 h. A suitable dosage regimen for the intravenous administration of kanamycin was also calculated.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01839170
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  • 9
    Digitale Medien
    Digitale Medien
    Pharmacokinetics and dosage regimen of cefotaxime in cross-bred calves following single intramuscular administration (1994)
    Springer
    Veterinary research communications 18 (1994), S. 313-318 
    Details
    ISSN: 1573-7446
    Schlagwort(e): calves ; cefotaxime ; cephalosporin ; dose ; intramuscular ; pharmacokinetics
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The pharmacokinetics, penetration into erythrocytes and plasma protein binding of cefotaxime were investigated in cross-bred calves. Following a single intramuscular dose of cefotaxime (10 mg/kg), the absorption half-life and elimination half-life were 0.13±0.03 h and 2.97±0.72 h, respectively. The apparent volume of distribution and total body clearance were 3.28±0.72 L/kg and 0.78±0.08 L/kg per h, respectively. The extent of penetration into erythrocytes was 24–40% of the total blood concentration. Cefotaxime was bound to plasma proteins of calves to the extent of 25.5–33.6%. A satisfactory intramuscular dosage regimen for cefotaxime in calves would be 11 mg/kg followed by 10 mg/kg at 7 h intervals.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01839199
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  • 10
    Digitale Medien
    Digitale Medien
    Pharmacokinetics following a single intravenous administration and a dosage regimen for sulfadoxine in buffalo calves (Bubalus bubalis) (1992)
    Springer
    Veterinary research communications 16 (1992), S. 215-219 
    Details
    ISSN: 1573-7446
    Schlagwort(e): pharmacokinetics ; dosage regimen ; sulfadoxine ; Bubalus bubalis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01839158
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