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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 625-625 
    ISSN: 1435-2451
    Keywords: Colorectal cancer ; Recurrence ; Reoperation ; CEA ; Colorectales Carcinom ; Rezidiv ; Chirurgische Therapie ; CEA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Von 1978–1984 wurden 87 Patienten wegen lokoregionärer Rezidive (35) und metachroner Fernmetastasen (52) colorectaler Carcinome operiert. 28,6% der Patienten mit Rezidiven und 46,2% der Patienten mit Metastasen konnten potentiell kurativ therapiert werden. Zum Zeitpunkt der gesicherten Diagnose hatten 73/87 Patienten einen erhöhten CEA-Wert (≧5 ng/ml). Bei 65/73 Patienten ging der CEA-Ànsbeg der Diagnose voraus. Bei 14 Patienten wurde die Diagnose erst durch eine Second-Look-Operation gesichert. Rezidivpatienten (71,4%) wiesen gegenüber Patienten mit Metastasen (92,3%) seltener erhöhte CEA-Werte auf. Die CEA-Werte der potentielle kurativ operablen Patienten (median 19,7 ng/ml) waren signifikant niedriger (p 〈 0,05) als bei Patienten mit inoperablen Befunden (median 36,9 ng/ml).
    Notes: Summary Between 1978 and 1984, 87 patients with recurrent colorectal cancer have been operated upon. In 10 of 35 patients with locoregional recurrence and 24 of 52 with distant metastases, the therapy was potentially curative. Of 87 patients, 73 had elevated CEA levels (≧ 5 ng/ml) at the time of diagnosis. In 65 of 73 patients, the CEA increase preceded the recognition of recurrence and in 14 patients the diagnosis could be confirmed only by a second-look operation. Patients with metastases (91.3%) showed CEA elevation more often than those with locoregional recurrence (71.4%). Patients with operable disease had significantly (p 〈 0.05) lower CEA values (median 19.7 ng/ml) than those with inperable recurrent carcinomas (median 36.9 ng/ml).
    Type of Medium: Electronic Resource
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