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  • Articles: DFG German National Licenses  (2)
  • 1,25-Dihydroxy vitamin D3  (1)
  • Circulatory regulation  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 62 (1984), S. 93-96 
    ISSN: 1432-1440
    Keywords: Renal transplantation ; Steroid osteoporosis ; 1,25-Dihydroxy vitamin D3 ; Immunosuppressive therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forearm bone mineral content (BMC), as evaluated by photonabsorption densitometry, was measured in 28 cadaver kidney donor recipients who entered the study 8 weeks postoperatively and were followed up for 18 months. BMC decreased signifiantly (p〈0.05) but marginally in placebo-treated patients (n=14) (initial BMC 1.09±0.25 g/cm; final BMC 1.05±0.24). Fourteen patients were prophylactically given 1,25(OH)2vitamin D3 in a dose which avoided hypercalcemia and hypercalciuria (∼0.25 µg/day); under 1,25(OH)2 vitamin D3 prophylaxis a significant decrease of forearm BMC was observed no longer (initial BMC 0.94±0.21 g/cm; final BMC 0.95±0.21), but the difference between placebo and 1,25(OH)2 vitamin D3 narrowly missed statistical significance (p=0.066). It is concluded that the decrease of forearm BMC is negligible in transplant recipients with low steroid regimens. The data suggest a trend for prophylaxis with 1,25(OH)2 vitamin D3 to slightly ameliorate forearm (cortical) BMC loss.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1459
    Keywords: Shy-Drager syndrome ; Idiopathic orthostatic hypotension ; Plasma catecholamines ; Circulatory regulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei einer Patientin mit Shy-Drager-Syndrom wurden Plasmakatecholamine und Kreislaufparameter untersucht. Die basalen Werte an freiem Noradrenalin und Dopamin waren im Normbereich, Adrenalin erniedrigt. Die Reaktion der Plasmakatecholamine auf verschiedene Arten körperlicher Belastung war deutlich pathologisch. Die Unfähigkeit, die Plasmakatecholamine vor allem während längerer Aktivität auf erhöhtem Niveau zu halten, entsprach der beeinträchtigten Kreislaufregulation und kann als weiteres diagnostisches Kriterium angesehen werden.
    Notes: Summary Plasma catecholamines and circulation parameters were studied in a patient with a Shy-Drager syndrome. Basal values of free noradrenaline and dopamine were within the normal range, whereas the adrenaline level was decreased. The response of plasma catecholamines to different kinds of physical activity was pathological. The inability to maintain elevated catecholamine levels during prolonged activity corresponded to impaired circulatory regulation and may provide an additional tool for diagnosis and monitoring of the Shy-Drager syndrome.
    Type of Medium: Electronic Resource
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