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  • 1
    ISSN: 1619-7089
    Keywords: Medullary carcinoma ; 99mTc(V)-DMSA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 99mTc(V)-DMSA kits developed by the Radiopharmaceutical Division, Bhabha Atomic Research Centre, have been evaluated for potential use in scanning medullary carcinoma of the thyroid and its metastases. There were 15 patients with proved medullary carcinoma and 6 patients with other differentiated thyroid carcinoma. Amongst the 15 patients with medullary carcinoma, 12(80%) showed positive localisation either in the primary or one or more metastatic sites. None of the six patients with carcinoma other than medullary showed increased concentration of 99mTc (V)-DMSA. Of the 37 known metastatic sites in 15 patients with medullary carcinoma, 24 showed concentration of 99mTc (V)-DMSA (64.9%). In addition, 99mTc(V)-DMSA concentration was seen in 14 sites where no evidence of metastasis was revealed. The incidence of 99mTc (V)-DMSA concentration in soft tissue and bone metastasis was similar.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1619-7089
    Keywords: 99mTc(V)-DMSA ; Medullary carcinoma ; Tumour imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Consequent to the promising results reported with 99mTc(V)-DMSA for imaging certain types of soft tissue tumors, we have developed methods to prepare this radiopharmaceutical in three ways:-(i) from freshly prepared reagents, (ii) through the use of a two component kit and (iii) use of the standard renal DMSA kit by a modified recipe. The 99mTc(V)-DMSA complex has been subjected to paper electrophoretic and chromatographic procedures and also biodistribution studies. The distinctly different behaviour of this new product compared to that of the well known renal DMSA complex has been clearly established. Scintiimaging in a preliminary clinical trial in patients with medullary carcinoma of the thyroid has been encouraging.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 5 (1985), S. 225-244 
    ISSN: 0271-2091
    Keywords: Convection-Diffusion ; Differencing Schemes ; Discretization Errors ; False Diffusion ; Upwind Scheme ; Higher Order Schemes ; Accuracy ; Stability ; Computational Cost ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A comparative study of seven discretization schemes for the equations describing convection-diffusion transport phenomena is presented. The (differencing) schemes considered are the conventional central- and upwind-difference schemes, together with the Leonard,1 Leonard upwind1 and Leonard super upwind difference1 schemes. Also tested are the so called locally exact difference scheme2 and the quadratic-upstream difference scheme.3,4 In multidimensional problems errors arise from ‘false-diffusion’ and function approximations. It is asserted that false diffusion is essentially a multidimensional source of error. No mesh constraints are associated with errors in function approximation and discretization. Hence errors associated with discretization only may be investigated via one-dimensional problems. Thus, although the above schemes have been tested for one- and two-dimensional flows with sources, only the former are presented here. For 1D flows, the Leonard super upwind difference scheme and the locally exact scheme are shown to be far superior in accuracy to the others at all Peclet numbers and for most source distributions, for the test cases considered. Furthermore, the latter is shown to be considerably cheaper in computational terms than the former. The stability of the schemes and their CPU time requirements are also discussed.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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