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  • 1
    ISSN: 1432-1084
    Keywords: Key words: CT ; Coronary disease ; Coronary arteriosclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. To identify patients with increased risk of having coronary artery disease (CAD), electron-beam computed tomography (EBCT) was used for years for quantifying calcifications of the coronary arteries. The first direct comparison between EBCT and conventional CT was performed to determine the reliability of widely available conventional CT for the assessment of the coronary calcium score. Fifty male patients with suspected CAD were investigated with both modalities, EBCT and conventional 500-ms non-spiral partial scan CT. Scoring of the coronary calcification was performed according to the Agatston method. Forty-two of these patients underwent coronary angiography for the assessment of significant luminal narrowing. The correlation coefficient of the score values of both modalities was highly significant (r = 0.982, p 〈 0.001). The variability between the two modalities was 42 %. Mean calcium score in patients with significant coronary luminal narrowing (n = 37) was 1104 ± 1089 with EBCT and 1229 ± 1327 with conventional CT. In patients without luminal narrowing (n = 5) mean calcium score was 73 ± 57 with EBCT and 26 ± 35 with conventional CT. Although images of the heart from conventional CT may suffer from cardiac motion artifacts, conventional CT has the potential to identify patients with CAD with accuracy similar to EBCT.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Internist 39 (1998), S. 19-32 
    ISSN: 1432-1289
    Keywords: Schlüsselwörter Tachyarrhythmie ; Therapie ; Tachyarrhythmie ; supraventrikuläre ; Herzrhythmusstörungen ; Therapie ; Antiarrhythmika ; Therapie ; Antiarrhythmika ; Nebenwirkungen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zum Thema In dieser Arbeit wird ein Überblick über die medikamentöse Differentialtherapie supraventrikulärer Tachyarrhythmien unter Berücksichtigung des jeweiligen pathophysiologischen Zustands gegeben. Trotz Katheterablation sind antiarrhythmische Medikamente zur Akutbehandlung und Rezidivprophylaxe supraventrikulärer Tachyarrhythmien unersetzlich. Schon vor Beginn einer antiarrhythmischen Pharmakotherapie sollte der Patient über mögliche unerwünschte Nebenwirkungen, besonders proarrhythmische, aufgeklärt werden (vgl. dazu auch die Arbeit von T. Meinertz et al. In diesem Heft). Bei Risikopatienten mit manifester Herzinsuffizienz, symptomatischer koronarer Herzkrankheit, vorbekannter Proarrhythmie oder Kammertachykardie, muß die Einleitung einer antiarrhythmischen Behandlung unter stationären Bedingungen erfolgen. Der Elektrolythaushalt sollte ausgeglichen sein. Für bestimmte Antiarrhythmika bestehen aufgrund von Vorbefunden Kontraindikationen; kardiale, wie z.B. die negativ inotrope Wirkung von Betarezeptorenblockern, sind dabei ebenso wie extrakardiale Nebenwirkungen zu beachten, z.B. die Lungenfibrose bei Amiodaron. Zusammenfassende Therapieempfehlungen finden sich am Ende der Arbeit im „Fazit”, worauf aus pragmatischen Gründen besonders hingewiesen sei.
    Type of Medium: Electronic Resource
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