ISSN:
1432-1912
Keywords:
Cyclic AMP
;
Hypothalamus
;
Genetically hypertensive rats
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In genetically hypertensive rats an altered catecholamine content of hypothalamic structures has been reported. In the present study cAMP was estimated in the hypothalamus and cortex of genetically hypertensive rats and compared with normotensive controls of the same strain. It is shown, that the cAMP content of the hypothalamus of the hypertensive animals was decreased to about 60% of control values, whereas there was no difference of the cAMP content in the cortical regions of the same animals. These results indicate an alteration of the adenyl cyclase-cAMP-phosphodiesterase system in hypothalamic structures of genetically hypertensive rats.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00508306
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