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  • Diabetes  (3)
  • rat  (3)
  • Insect sensilla  (2)
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  • 1
    ISSN: 1432-0428
    Schlagwort(e): Diabetes ; growth hormone ; hypertrophy ; kidney ; rat ; streptozotocin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Normal and diabetic rats were given daily injections of human growth hormone for four days (5 mg per rat per day). Injected rats showed no differences from uninjected controls with respect to kidney weight or renal content of protein, RNA or DNA. Kidney weight increased by 7% after two days of diabetes and by 20% after four days, but growth hormone caused no augmentation of the hypertrophy. It is concluded that growth hormone plays no role in the initiation of diabetic renal hypertrophy.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Diabetologia 18 (1980), S. 501-505 
    ISSN: 1432-0428
    Schlagwort(e): Diabetes ; glomerulus ; hypertrophy ; kidney ; morphometry ; nephrectomy ; proximal tubule ; rats ; stereology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Renal hypertrophy in rats with streptozotocin diabetes or after unilateral nephrectomy was studied by sterological techniques. — After 4 days of diabetes total glomerular volume had increased by 30%, and after 47 days by 43%. Glomerular growth was more pronounced than whole kidney growth during the first 4 days, but subsequently whole kidney growth exceeded glomerular growth. In control rats glomerular volume was 4.9% of total kidney volume; after 4 days of diabetes it was 5.4% and after 47 days 4.1%. — Proximal tubule length increased from 366 m/kidney in control rats to 447 m/kidney after 47 days of diabetes; tubular luminal diameter increased from 26.8 μm to 31.4 μm in the same rats. Tubular length and luminal diameter were, however, not increased after 4 days of diabetes. — In unilaterally nephrectomised rats there was no early rapid glomerular growth. Glomerular fractional volume was 4.9% in controls, 4.4% at four days, and 4.2% at 24 days after nephrectomy. — The results indicate a disturbed glomerulo-tubular balance in the early phases of diabetic renal hypertrophy.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Diabetologia 14 (1978), S. 325-328 
    ISSN: 1432-0428
    Schlagwort(e): Diabetes ; hypertrophy ; kidney ; nephrectomy ; rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The kidney growth seen after the induction of experimental diabetes in rats has been compared to the compensatory renal growth after one-sided nephrectomy. After five days the kidney weight had increased from 650 ± 15 mg in a group of controls to 778 ± 21 mg in diabetic rats, and 764 ±17 mg in unilaterally nephrectomised rats. The increased weight was in both groups reflected in an increased DNA content and increased RNA/DNA and protein/DNA ratios. In a group of rats made diabetic and nephrectomised at the same time, kidney weight increased to 953 ± 22 mg after five days. When rats were unilaterally nephrectomised after 20 days of untreated diabetes, compensatory growth was much more pronounced than in non-diabetic rats, kidney weight rising from 780 ± 21 to 1144 ± 39 mg in five days. Similarly, in rats with established compensatory renal hypertrophy, diabetes induced a very rapid growth of the remaining kidney (1226 ± 46 mg after five days).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Diabetologia 13 (1977), S. 141-143 
    ISSN: 1432-0428
    Schlagwort(e): Blood glucose ; diabetes ; DNA ; hypertrophy ; kidney ; rat ; Streptozotocin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Streptozotocin diabetic rats have larger kidneys than non-diabetic rats. In the present study the rate of kidney growth during the first seven days of diabetes was correlated with the blood glucose concentration. Over a wide range of blood glucose concentrations (116–340 mg/100 ml) the kidney weight, protein content and protein/DNA ratio were closely correlated with the glucose values.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Cell & tissue research 132 (1972), S. 79-94 
    ISSN: 1432-0878
    Schlagwort(e): Insect sensilla ; Mechanoreceptors ; Tubular body ; Stimulus-conducting structures
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die Mechanorezeptorzellen der Tast- und Schmeckhaare auf der Antenne der Baumwollwanze besitzen einen tubulären Körper (TK), dessen Mikrotubuli an der Peripherie eine palisadenartig dichte (Abstand 100–200 Å) und im Zentrum eine annähernd hexagonale Anordnung (Abstand 300 Å) zeigen. Zwischen den peripheren Tubuli und der Dendritenmembran bestehen Brücken. Die Mikrotubuli sind durch senkrecht zu ihrer Achse orientierte Schichten elektronendichten Materials (Dicke und Abstand je 170 Å) verbunden. Proximal vom TK ist die Zahl der Tubuli stark reduziert. Im Sockelbereich beider Haartypen finden sich hebelartige Verlängerungen des Haarschafts, die dessen Auslenkung in eine Kompression des TK transformieren. Eine Beteiligung der Mikrotubuli des TK an der Reiz-Erregungs-Transduktion wird diskutiert.
    Notizen: Summary Mechanoreceptor cells of the touch- and taste hairs on the antenna of the red cotton bug possess a tubular body (TB). The TB contains microtubuli, which are 100–200 Å apart and arranged on palisades in the peripheral part of the TB, and about 300 Å apart and hexagonally arranged in the central part of the TB. Bridges (filaments) exist between the peripheral tubuli and the membrane of the dendrite. The microtubuli are connected by layers of dense material (of 170 Å thickness and distance) which are arranged perpendicularly to their axes. Proximal to the TB the number of the microtubuli is strongly reduced. In the joint region of both hair types the hairshafts show lever-like processes which transmit the bending effect of the hair into a compression of the TB. The role of the microtubuli in this transduction is discussed.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Cell & tissue research 207 (1980), S. 307-320 
    ISSN: 1432-0878
    Schlagwort(e): Insect sensilla ; Fine structure ; Odonata
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die vier Porensensillen des Maxillarpalpus von Agrion and Ischnura besitzen zwei (Sensillum Typ A), beziehungsweise fünf (Sensillum Typ B) bipolare Rezeptorzellen. Distal werden ihre Dendriten von der Dendritenscheide und dem Porusrohr umschlossen. Die Dendriteninnenglieder inserieren seitlich an den Perikarya. Die Rezeptorzellen jedes Sensillums sind von drei Hüllzellen und drei voneinander getrennten Rezeptorlymphräumen umschlossen. Rezeptorlymphraum l und 3 haben durch das Porusrohr, beziehungsweise durch das Porenkanalsystem der Cuticula Verbindung nach außen. Alle drei Hüllzellen zeigen apikal mikrovillusartige Membranstrukturen; außerdem besitzen sie je zwei Centriolen in Tandemstellung. Die Feinstruktur der Porensensillen wird mit der ähnlicher Arthropodensensillen verglichen. Funktionelle und phylogenetische Aspekte werden diskutiert.
    Notizen: Summary The four single-pore sensilla on the maxillary palp of Agrion and Ischnura possess two bipolar sensory cells for A-sensilla and five for B-sensilla. Distally, their dendrites are enclosed by a dendritic sheath and a pore tube. The dendritic tips have access to the outside via the opening of the pore tube. The inner dendritic segments join the receptor cell bodies laterally. The receptor cells of each sensillum are enveloped by three sheath cells and three receptor lymph cavities. Receptor lymph cavity 1 and 3 are connected with the outside by the pore tube and a minute canal system in the cuticle, respectively. All three sheath cells show microvilluslike processes of the apical membrane. Moreover, all sheath cells contain two centrioles in tandem arrangement. The structure of the single-pore sensilla is compared with that of similar sensilla of other arthropods. Functional and phylogenetic aspects are discussed.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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