Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    MR imaging of clear cell sarcoma (malignant melanoma of the soft parts): a multicenter correlative MRI-pathology study of 21 cases and literature review (2000)
    Springer
    Skeletal radiology 29 (2000), S. 187-195 
    Details
    ISSN: 1432-2161
    Keywords: Key words Clear cell sarcoma ; Malignant melanoma of soft parts ; MRI ; Magnetic resonance ; Neoplasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Objective. To evaluate MR imaging and pathology findings in order to define the characteristic features of clear cell sarcoma of the soft tissues (malignant melanoma of the soft parts). Design and patients. MR examinations of 21 patients with histologically proven clear cell sarcoma of the musculoskeletal system were retrospectively reviewed and assessed for shape, homogeneity, delineation, signal intensities on T1- and T2-weighted images, contrast enhancement, relationship with adjacent fascia or tendon, secondary bone involvement, and intratumoral necrosis. In 19 cases the pathology findings were available for review and for a comparative MR-pathology study. Results. On T1-weighted images, lesions were isointense (n=3), hypointense (n=7) or slightly hyperintense to muscle (n=11). Immunohistochemical examination was performed in 17 patients. All 17 specimens showed positivity for HMB-45 antibody. In nine of 11 lesions with slightly increased signal intensity on T1-weighted images, a correlative MR imaging-pathology study was possible. All nine were positive to HMB-45 antibody. Conclusions. Clear cell sarcoma of the musculoskeletal system often has a benign-looking appearance on MR images. In up to 52% of patients, this lesion with melanocytic differentiation has slightly increased signal intensity on T1-weighted images compared with muscle. As the presence of this relative higher signal intensity on T1-weighted images is rather specific for tumors displaying melanocytic differentiation, radiologists should familiarize themselves with this rare entity and include it in their differential diagnosis when confronted with a well-defined, homogeneous, strongly enhancing mass with slightly higher signal intensity compared with muscle on native T1-weighted images.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002560050592
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Maligne Knorpeltumoren (1998)
    Springer
    Der Radiologe 38 (1998), S. 502-508 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Chondrosarkom ; Radiologische Diagnose ; Magnetresonanztomographie (MRI) ; Kontrastmittel ; Key words Cartilage ; Sarcoma ; Diagnostic radiology ; Magnetic resonance (MR) ; contrast agents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Malignant cartilaginous tumors (chondrosarcomas) are, with a relative frequency of 20%, the second most common malignant tumors of bone after osteosarcoma. The diagnosis of chondrosarcoma can usually be made confidently based on combination of clinical information, radiographs, Gd-enhanced MR imaging, and histologic examination of a biopsy sample. The combination of these parameters is important because accuracy of histologic diagnosis is adversely affected by unrepresentative sampling of these usually large tumors. The prognosis of patients with chondrosarcoma becomes poorer with more axial location, higher histologic grade, larger tumor size and inadeqaute resection. By careful analysis of radiographs and Gd-enhanced MR imaging the radiologist has the ability to improve the management of patients with chondrosarcoma.
    Notes: Zusammenfassung Die malignen Knorpeltumoren oder Chondrosarkome treten in einer Inzidenz von 20% auf und sind damit die zweithäufigsten primären malignen Tumoren des Knochens nach dem Osteosarkom. Üblicherweise kann in Zusammenschau von klinischer Information, Nativröntgenbildern und Kontrastmittel-MR-Untersuchung sowie Histologie eine zuverlässige Diagnose gestellt werden. Es ist wichtig, alle diese Modalitäten in ihrer Gesamtheit zu betrachten, da die Histologien manchmal durch nichtrepräsentative Gewebsentnahmen aus diesen oft großen Tumoren ungenau sind. Die Prognose von Chondrosarkomen verschlechtert sich bei stammnaher Lokalisation, hohem Grading, zunehmender Tumorgröße und insuffizienter Resektion. Durch sorgfältige Interpretation von Röntgenaufnahmen und MR-Kontrastmitteluntersuchungen liegt es in der Hand des Radiologen die Behandlung von Chondrosarkompatienten zu optimieren.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050385
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...