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  • 1
    ISSN: 1432-1920
    Keywords: Cervical spinal cord ; Cervical spondylosis ; Computed tomography ; Computer-assisted myelography ; Metrizamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixty-nine patients with cervical spondylotic myelopathy (CSM), radiculopathy (CSR), or both (CSMR) were studied with computed tomography (CT). Computer-assisted myelography (CAM) accurately determines the site and nature of spondylotic protrusions and provides good visualisation of the subarachnoid space and cord deformities even in areas with dilute metrizamide. However, excessive vertebral movement and bulging ligamenta flava with their effects on cord deformity, so easily visualised in myelograms, are completely or partially missed. In the assessment of CSM, metrizamide myelography (MM) followed by CAM should be performed, particularly when the myelographic images are unsatisfactory due to contrast dilution or blockage, when cord compression cannot be ascertained with MM and when cord atrophy is suspected. In CSR, the diagnostic information from MM and CAM is comparable. The diagnostic criteria in CAM are, however, less direct and since MM is adequate in uncomplicated cases, CAM is generally not necessary. The APD, APD/TD ratio, area and circularity are sensitive indices of cord deformity and the first two should be used more often to assist visual assessment of cord deformity. The relation between cord parameters and treatment response is better reflected in CSM cases managed conservatively and the results suggest that the degree of cord deformity is helpful in determining the outcome and hence the choice between surgical and conservative treatment. In plain CT, the osteophytes and calcified discs are adequately visualised and canal dimensions measured with accuracy, but the cervical cord and roots cannot be properly assessed and the diagnosis of CSM or CSR cannot be ascertained. At present, its role in cervical spondylosis is therefore limited.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 28 (1986), S. 339-343 
    ISSN: 1432-1920
    Keywords: Water soluble contrast medium ; Side effects ; Metrizamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Although metrizamide is now being superseded by other contrast media, the mechanisms of its side effects may be of fundamental importance. One hundred and four consecutive patients with suspected cervical cord or root lesion were studied prospectively for factors which might influence the side effects of metrizamide myelography. Elderly patients were more prone to develop mental confusion. An earlier onset of dizziness and/or vertigo was associated with the lumbar route of intrathecal injection. Perhaps surprisingly, phenobarbitone prophylaxis shortened the duration of confusion and delayed the onset of headaches. Other factors, viz. sex, excess intracranial flow of metrizamide and myelographic blockage were not shown to have a significant influence on the adverse reactions.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 26 (1984), S. 399-403 
    ISSN: 1432-1920
    Keywords: Metrizamide ; myelography ; risks ; complications
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The safety of post-myelogram computed tomography (PMCT) as an additional diagnostic procedure to metrizamide myelography was evaluated. One hundred and four consecutive patients with suspected cervical cord lesions were studied prospectively; 50 had both myelography and PMCT, and the 54 acting as controls had only myelography. PMCT did not increase the incidence, severity or duration of common side effects and the majority of patients accepted this additional procedure. It is concluded that as long as care is taken to avoid the occurrence of excessive contrast in the intracranial subarachnoid space, PMCT is a safe procedure.
    Type of Medium: Electronic Resource
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