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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 71 (1993), S. 825-829 
    ISSN: 1432-1440
    Keywords: Rapidly progressive glomerulonephritis ; Crescents ; Anti-nuclear cytoplasmic autoantibodies ; Anti-glomerular basement membrane disease ; Pathogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2048
    Keywords: Glutamine synthetase ; Nitrate (as inductor) ; Nitrite reductase ; Phytochrome (as inductor) ; Sinapis (nitrate assimilation)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The extent to which the appearances of nitrite reductase (NIR; EC 1.7.7.1) and glutamine synthetase (GS; EC 6.3.1.2) are coordinated was studied in mustard (Sinapis alba L.) seedlings. It was established by immunotitration that the increased activities of NIR and GS in the presence of light and nitrate can be attributed to the de-novo synthesis of enzyme protein. The bulk of the NIR and GS was found in the developing cotyledons. In the absence of nitrate in the growth medium there was no coordinate appearance of NIR and GS. While light strongly stimulated the appearance of GS, the level of NIR was hardly affected and remained low. On the other hand, in the presence of nitrate in the medium the appearances of NIR and GS were strictly coordinated, the GS level being considerably above that of NIR. It is argued that phytochrome-controlled synthesis of GS in the absence of nitrate is part of the mechanism to reassimilate ammonium liberated during proteolysis of storage protein and metabolism of the resulting amino acids, whereas the strictly coordinated synthesis in the presence of light and nitrate indicates the dominance of nitrate assimilation under these circumstances. The fact that the level of GS was always considerably above that of NIR appears to be a safety measure to prevent ammonium accumulation.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Nervenarzt 71 (2000), S. 123-129 
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Somatoparaphrenie ; Anosognosie für Hemiplegie ; Parietaler Kortex ; Thalamus ; Neglekt ; Fehlidentifikation ; Pathogenese ; Key words Somatoparaphrenia ; Anosognosia for hemiplegia ; Parietal cortex ; Thalamus ; Neglect ; Misidentification ; Pathogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Anosognosia for hemiplegia (AHP), i. e., unawareness of motor deficits and associated disorders, has been frequently reported, predominantly following right hemispheric lesions. To a smaller extent, there are case reports of patients who give accounts of a feeling of strangeness concerning the contralesional limbs and sometimes attribute them to other persons. This “positive-variant” of AHP has been labeled “somatoparaphrenia” (SP). We report a case of SP in a 85-year-old woman with infarction of the right posterior cerebral artery and posterior parts of the right thalamus. She showed AHP and described her left side alternatively as her handicapped nephew and a clumsy cat. Misidentification of her daughter also occurred. With respect to the literature the predominant neuroanatomical features involved are lesions including right parietal cortex and/or posterior parts of the thalamus. Theories concerning the pathogenesis of this phenomenon comprise a denial of the illness, a lack of awareness caused by reduced sensory feedback and neglect, a misidentification or disturbance of the active discovery process considered necessary for realizing one's disorder.
    Notes: Zusammenfassung Anosognosie für Hemiplegie (AHP) im Sinne einer mangelnden Bewusstheit einer Hemiparese und assoziierter Störungen ist in Folge überwiegend rechtshemisphärischer Läsionen ein häufigeres Phänomen. Seltener wird kasuistisch über Patienten berichtet, die zusätzlich ein Fremdheitsgefühl kontraläsioneller Körperteile angeben und sie z. B. anderen Personen zuschreiben. Diese “Plusvariante” der AHP wird als Somatoparaphrenie (SP) bezeichnet. Wir schildern den Fall einer 85-jährigen Frau, die nach einem rechtshemisphärischen Infarkt der A. cerebri posterior und posteriorer Anteile des Thalamus eine SP entwickelte. Bei bestehender AHP äußerte sie abwechselnd, ihre linke Körperseite sei ihr körperbehinderter Neffe oder eine ungeschickte Katze. Passager traten auch Fehlidentifikationen der Tochter auf. In der Literatur werden überwiegend Läsionen unter Einschluss des rechten parietalen Kortex und/oder des rechten posterioren Thalamus angegeben. Erklärungstheorien umfassen u. a. psychodynamische Ansätze im Sinne einer Krankheitsverdrängung, ein Wahrnehmungsdefizit durch einen mangelnden sensorischen Feedback und Neglekt, eine Fehlidentifikation, sowie eine Beeinträchtigung eines zur Bewusstwerdung körperlicher Störungen notwendigen aktiven Aufdeckungsprozesses.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2048
    Keywords: Glutamine synthetase ; Nitrate (as inductor) ; Nitrite reductase ; Phytochrome (as inductor) ; Sinapis (nitrate assimilation)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The extent to which the appearances of nitrite reductase (NIR; EC 1.7.7.1) and glutamine synthetase (GS; EC 6.3.1.2) are coordinated was studied in mustard (Sinapis alba L.) seedlings. It was established by immunotitration that the increased activities of NIR and GS in the presence of light and nitrate can be attributed to the de-novo synthesis of enzyme protein. The bulk of the NIR and GS was found in the developing cotyledons. In the absence of nitrate in the growth medium there was no coordinate appearance of NIR and GS. While light strongly stimulated the appearance of GS, the level of NIR was hardly affected and remained low. On the other hand, in the presence of nitrate in the medium the appearances of NIR and GS were strictly coordinated, the GS level being considerably above that of NIR. It is argued that phytochrome-controlled synthesis of GS in the absence of nitrate is part of the mechanism to reassimilate ammonium liberated during proteolysis of storage protein and metabolism of the resulting amino acids, whereas the strictly coordinated synthesis in the presence of light and nitrate indicates the dominance of nitrate assimilation under these circumstances. The fact that the level of GS was always considerably above that of NIR appears to be a safety measure to prevent ammonium accumulation.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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