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  • 1990-1994  (2)
  • Gastrointestinal tract  (1)
  • RFLP  (1)
Material
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  • 1990-1994  (2)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 4 (1994), S. 371-376 
    ISSN: 1432-1084
    Keywords: Contrast media ; Gastrointestinal tract ; Infants ; Iotrolan ; Radiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Over the past 5 years we have used the new dimeric, non-ionic, water-soluble contrast agent iotrolan (Isovist-300) in 370 studies of the paediatric gastrointestinal tract. Iotrolan is by far the best accepted and tolerated contrast agent for young children. Because of its iso-osmolality it can be used without dilution. No ill effects were reported in cases of aspiration or perforation. In all studies very high contrast images were obtained and the required diagnostic information was provided. The only disadvantage of iotrolan is its present high price. However, in view of the small volumes required in children (10 ml is sufficient in 59% and 20 ml sufficient in 92% of investigations) this should not be a major obstacle to its use. Iotrolan promotes a much greater readiness among paediatricians and paediatric surgeons to have gastrointestinal studies performed on very small and very sick babies.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2242
    Keywords: RFLP ; Potato ; Tomato ; Genetic maps
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary An RFLP linkage map of the potato is presented which comprises 304 loci derived from 230 DNA probes and one morphological marker (tuber skin color). The self-incompatibility locus of potato was mapped to chromosome I, which is homoeologous to tomato chromosome I. By mapping chromosome-specific tomato RFLP markers in potato and, vice versa, potato markers in tomato, the different potato and tomato RFLP maps were aligned to each other and the similarity of the potato and tomato genome was confirmed. The numbers given to the 12 potato chromosomes are now in accordance with the established tomato nomenclature. Comparisons between potato RFLP maps derived from different genetic backgrounds revealed conservation of marker order but differences in chromosome and total map length. In particular, significant reduction of map length was observed in interspecific compared to intraspecific crosses. The distribution of regions with distorted segregation ratios in the genome was analyzed for four potato parents. The most prominent distortion of recombination was found to be caused by the self-incompatibility locus.
    Type of Medium: Electronic Resource
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