Bibliothek

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • 1980-1984  (105)
  • 1915-1919
  • 1905-1909
  • Ultrastructure  (105)
  • 1
    Digitale Medien
    Digitale Medien
    Meningeal granulocytic sarcoma without evidence of leukemia (1981)
    Springer
    Virchows Archiv 392 (1981), S. 111-118 
    Details
    ISSN: 1432-2307
    Schlagwort(e): Granulocytic sarcoma ; Chloroma ; Meningeal sarcoma ; Ultrastructure ; Myelogenous leukemia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary An unusual case of meningeal granulocytic sarcoma without evidence of Leukemia is presented. The patient, a 40 year old female, presented with a chronic subdural haematoma. Three months later a large meningeal tumor was discovered adjacent to the previous haematoma and was found to be a granulocytic sarcoma by the use of electron microscopy. The tumor was treated by surgical excision followed by radiotherapy and chemotherapy. The patient remains free of symptoms and without evidence of leukemia in the peripheral blood or bone marrow 9 months after the diagnosis was established. The ultrastructural findings in the tumor and diagnostic difficulties often encountered are emphasized.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00430554
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Esthesioneuroblastoma: Ultrastructural, immunohistological and biochemical investigation of one case (1984)
    Springer
    European archives of oto-rhino-laryngology and head & neck 239 (1984), S. 133-144 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Esthesioneuroblastoma ; Intermediate filaments ; Secretory granules ; Ultrastructure ; Immunohistology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A case of esthesioneuroblastoma, the pathological diagnosis of which almost always causes great difficulties, was investigated ultrastructurally, biochemically, and immunohistologically, using antibodies against the five known types of intermediate filaments [keratin, vimentin, desmin, glial fibrillary acidic protein (GFAP) and neurofilaments]. The tumour cells did not react with antibodies against any of the five intermediate filament proteins. Ultrastructural investigations showed dense cored secretory granules in the cytoplasm and cell processes. Thus, immunohistology offers by “exclusion” a differential diagnosis to avoid often misdiagnosed tumours (undifferentiated carcinomas, embryonal rhabdomyosarcomas, and malignant lymphomas), since carcinomas react with antikeratin, embryonal rhabdomyosarcomas with antibodies to desmin and malignant lymphomas show immunofluorescence with antibodies to vimentin. The biological behaviour (age distribution, tendency to metastasize), the normal values of biochemical parameters, homovanillic acid and vanilmandelic acid (HVA, VMA), and the absence of neurofilaments distinguish this type of tumour from the peripheral sympathetic neuroblastoma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00463554
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Electron microscopy of avian osteopetrosis induced by retrovirus MAV.2-O (1982)
    Springer
    Calcified tissue international 34 (1982), S. 382-390 
    Details
    ISSN: 1432-0827
    Schlagwort(e): Avian osteopetrosis ; Avian oncornavirus ; Ultrastructure ; Calcification ; Bone cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Notizen: Summary Diaphyseal tibial bone of 12.5 – 13-day and 19-day-old embryos and 20-day-old hatched chicks infected with retrovirus MAV.2-O were examined by transmission electron microscopy. The viruses were associated with lining osteoblasts and osteocytes. Whereas the infection of the osteoblast layer seemed to be a transient stage, virus association with osteocytes was a constant and main ultrastructural feature. The viruses were found either in the osteoid or in the periosteocytic space of the bone lacunae. They arose from dense cytoplasmic areas located near the cell plasmalemma via a budding process. The newly budded virus particles often had a large tail or a fine stalk-like process lost in the extracellular space. The viruses underwent calcification by deposition of inorganic material and were incorporated in the bone trabeculae. No production of virus was observed in typical osteoclasts with well-differentiated ruffled borders. The viral-induced avian osteopetrosis seemed to result from increased bone deposition through stimulation of osteoblast and osteocyte activities, whereas osteoclastic bone resorption seemed to be undisturbed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02411272
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 4
    Digitale Medien
    Digitale Medien
    Ultrastructural findings in so-called ependymal rat tumors induced by transplacental administration of ethylnitrosourea (ENU) (1982)
    Springer
    Acta neuropathologica 57 (1982), S. 51-58 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Ependymoma ; Rat ; Ethylnitrosourea ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Tumors of the central nervous system (CNS) in Sprague-Dawley and Lewis rats were induced transplacentally by a single intraperitoneal (IP) injection of 10–25 mg/kg ethylnitrosourea (ENU) on days 16–20 of gestation. Light-microscopic examination revealed that 22% of these tumors could be diagnosed as ependymomas, anaplastic ependymomas (ependymoblastomas), or mixed tumors revealing both oligodendroglioma and anaplastic ependymoma tissues if the criteria of accepted classifications were followed. Electron-microscopic examination, however, demonstrated that the ependymoma and the anaplastic ependymoma-like tissue in ENU-induced tumors lacked ependymal features, such as basal bodies, cilia, complicated junctional complexes, microvilli, etc. This tissue type was repetitious, always being composed of cells arranged in groups, cords, and rosette-like (pseudorosette) formations. In the pseudorosettes, the cell nuclei were polarized at the periphery and the cytoplasm contained numerous polyribosomes, occasional short microtubules and usually a few small dense-core vesicles. The center of the pseudorosettes showed numerous slender interdigitating processes interconnected by maculae adherens. The tips of these processes showed vesicular degeneration. The cells arranged in groups or cords and perivascular rosettes revealed identical ultrastructure, but they were not polarized. The present findings indicate that the socalled ENU-induced ependymomas and anaplastic ependymomas are not true ependymal tumors, but rather primitive neuroepithelial neoplasms with some features of oligodendroglioma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00688877
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 5
    Digitale Medien
    Digitale Medien
    Chroococcus S24 and Chroococcus N41 (cyanobacteria): morphological, biochemical and genetic characterization and effects of water stress on ultrastructure (1983)
    Springer
    Archives of microbiology 135 (1983), S. 81-90 
    Details
    ISSN: 1432-072X
    Schlagwort(e): Cyanobacteria ; Ultrastructure ; Nitrogen fixation ; Water stress ; Taxonomy ; DNA ; Plasmids
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Two strains of desiccation-tolerant coccoid cyanobacteria, Chroococcus S24, a marine form, and Chroococcus N41, a cryptoendolith isolated from a hot-desert rock, have been characterized. The mol % DNA base compositions of the strains are 47.1 and 48.9% respectively. Plasmid DNA was not detected in either strain. The pigment contents and nutritional characteristics of the strains are identical. Both lack phycoerythrinoid pigments and, in culture, behave as slow-growing halotolerant marine forms with elevated requirements for Na+, Cl−, Mg2+ and Ca2+. Sucrose was the only carbon source of those tested that supported photoheterotrophic growth. Each strain synthesizes nitrogenase under anaerobic conditions but not in air. Morphologically the two strains are indistinguishable. They are considered to be independent isolates of the same cyanobacterial species. Chroococcus N41 was studied in detail with the electron microscope. When brought to equilibrium at matric water potentials of-168 MPa and lower (to-673 MPa=c0.12a w) the protoplast shrinks, but the cells maintain the same size and diameter as those at-2,156 kPa (MN medium; control); the sheath expands and remains attached to the cell wall outer membrane by fibrils. The cell wall, cell membrane, thylakoid membranes, cyanophycin granules and carboxysomes appeared intact in desiccated cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00408014
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 6
    Digitale Medien
    Digitale Medien
    Neuropathological findings of an autopsy case of adult β-galactosidase and neuraminidase deficiency (1983)
    Springer
    Acta neuropathologica 61 (1983), S. 283-290 
    Details
    ISSN: 1432-0533
    Schlagwort(e): β-Galactosidase and neuraminidase deficiency ; Neuronal inclusion bodies ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary An autopsy case of a Japanese male with familial β-galactosidase and neuraminidase deficiency is reported. The clinical picture was characterized by adult onset, a gargoyle-like face, cerebellar ataxia, myoclonus, convulsions, retinal degeneration and cortical blindness. Histopathologically, most neurons seemed to have become degenerated in the whole cerebral cortex. Moreover, the calcarine cortex appeared spongy with depopulation of nerve cells. Stuffed neurons or neuronal storage changes were found throughout the brain, especially in the motor nuclei of the spinal cord and brain stem. The inclusions in the stuffed neurons revealed various profiles on the electron microscope. They were composed of membranous lamellar and/or multilamellar structures, often accompanying vacuoles and reminiscent of lipofuscin-like profiles.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00691999
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 7
    Digitale Medien
    Digitale Medien
    Pituitary adenomas: Immunohistology and ultrastructural analysis of 118 tumors (1983)
    Springer
    Acta neuropathologica 62 (1983), S. 1-14 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Pituitary adenomas ; Immunohistology ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary An analysis is presented of the immunohistological and ultrastructural features in a series of 118 surgically removed pituitary adenomas all of which were studied immunohistologically using antisera to growth hormone (GH), prolactin (PRL) ACTH, βFSH, βLH and βTSH, and 75 of which were studied ultrastructurally. Results were analysed according to the mode of presentation of patients. Forty-one (35%) of the tumours were from patients with acromegaly or gigantism, ten (9%) from patients with Cushing's syndrome or Nelson's syndrome, 19 (16%) from patients with clinical features associated with hyperprolactinaemia and 48 (40%) from patients with space occupying lesions which appeared clinically to be overtly endocrinologically functionless. By light microscopy, using the immunoperoxidase (PAP) technique, immunoreactive GH was demonstrated in all the tumours from patients with acromegaly or gigantism, immunoreactive ACTH in all tumours from patients with Cushing's syndrome or Nelson's syndrome and immunoreactive PRL in 95% of tumours associated with effects of hyperprolactinaemia. Forty-five percent of the tumours from acromegalic patients contained some PRL-positive cells as well as GH-positive cells. Among the tumours which appeared clinically to be endocrinologically functionless were three tumours (from males) uniformly stained for immunoreactive PRL. Of the remainder, 60% were negative for immunoreactive hormones and 40% contained small numbers of cells which were positive for a variety of immunoreactive hormones. ACTH-cell and PRL-cell tumours had ultrastructural features as described in previous studies. Fifty percent of GH-cell tumours examined at the EM level contained fibrous bodies, while in the remainder these structures were not identified. Tumours with fibrous bodies were more likely to contain PRL as well as GH with immunoperoxidase. All tumours that were endocrinologically functionless and which were examined at the EM level contained secretory granules. Oncocytic change was common in these tumours. No ultrastructural differences were observed between those which contained immunoreactive hormones by light microscopy and those which did not.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00684914
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 8
    Digitale Medien
    Digitale Medien
    An ultrastructural and histochemical study of the axial musculature in the African lungfish (1981)
    Springer
    Cell & tissue research 220 (1981), S. 599-609 
    Details
    ISSN: 1432-0878
    Schlagwort(e): Axial musculature ; Lungfish ; Histochemistry ; Ultrastructure ; Evolution
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Red, intermediate, and white axial muscle fibres of African lungfish were studied using histochemical techniques and electron microscopy. Gross dissection revealed the presence of a small wedge of red coloured muscle along the lateral line. This wedge was shown by histochemical demonstrations of lactate and succinate dehydrogenases, of adenosine triphosphatases, and of lipid to be composed of a mosaic of red and intermediate fibres measuring 23.63 and 34.30 μm in average diameter, respectively. The bulk of the myotome was composed of white fibres having an average diameter of 67.35 μm. Mitochondrial density, capillarity and lipid content were very low for all fibres. These data suggest that the axial musculature is geared primarily for anaerobic function. The mosaic arrangement of fibres, and the lack of a subsarcolemmal band of mitochondria suggests that the lungfish have a muscle organisation that is transitional between lower vertebrates and amphibians.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00216763
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 9
    Digitale Medien
    Digitale Medien
    Ultrastructure of the rat thymus: The micro-environment of T-lymphocyte maturation (1981)
    Springer
    Cell & tissue research 218 (1981), S. 279-292 
    Details
    ISSN: 1432-0878
    Schlagwort(e): Thymus micro-environment (rat) ; Epithelial cells ; Macrophages ; Interdigitating cells ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The ultrastructure of the micro-environment of the fully functional rat thymus was studied. The thymus consists of two discrete compartments, viz., an epithelial and a mesenchymal compartment. Thymus fibroblasts/fibrocytes, mast cells and granulocytes, are restricted to the mesenchymal compartment. The thymocyte maturation process seems to occur in the epithelial compartment in a network of reticular epithelial cells. The cortex is finely meshed and filled with proliferating thymocytes and some scattered macrophages. Moreover, in the medulla vacuolated epithelial cells form part of a loosely meshed reticulum which is filled with thymocytes and interdigitating cells (IDCs). IDCs frequently contain Birbeck granules and appear to be phagocytic. Together with macrophages, they probably enter the thymus, predominantly in the cortico-medullary region, and cross the separating wall between the two compartments. Some functional aspects of the non-lymphoid cells and in particular the IDCs, which form the micro-environment of the thymus, are discussed with respect to T-cell development.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00210344
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 10
    Digitale Medien
    Digitale Medien
    Structure of the non-lymphoid cells during the postnatal development of the rat lymph nodes (1983)
    Springer
    Cell & tissue research 229 (1983), S. 219-232 
    Details
    ISSN: 1432-0878
    Schlagwort(e): Lymph nodes ; Postnatal development ; Fibroblastic reticulum cells ; Interdigitating cells ; Deep cortex units ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary This study describes the postnatal development of the nonlymphoid cells with special reference to the fibroblastic reticulum cells (FRCs) and interdigitating cells (IDCs). The first lymphocytes of the neonatal lymph nodes are located in the developing deep cortex units (DCUs) identified by the Gomori's technique for reticulin fibres. Ultrastructural studies demonstrate that FRCs form the stroma of the DCUs. By light and electron microscopy, it is demonstrated that FRCs occupy the outer cortex in the following stages of development of the lymph nodes. Thus, FRCs form the stroma of the primary follicles and, later, are transformed in follicular dendritic cells (FDCs) of the germinal centres. Immature or pro-IDCs appear as migrating elements in the deep cortex of lymph nodes of the neonatal rats. The ultrastructure of the pro-IDCs resembles that of the mature IDCs but not that of the phagocytic cells. Pro-IDCs are transformed into mature IDCs whose cytoplasmic expansions contact lymphocytes via tight junctions. Some of these lymphocytes are likely apposed to FRCs of the DCUs. No cells containing Birbeck granules were found in the parenchyma of the lymph nodes during the postnatal development. The role of these nonlymphoid cells is discussed with respect to the immunologic function of mammalian lymph nodes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00217894
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...