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  • 1
    Electronic Resource
    Electronic Resource
    Histological signs of immune reactions against allogeneic solid fetal neural grafts in the mouse cerebellum depend on the MHC locus (1988)
    Springer
    Experimental brain research 73 (1988), S. 15-22 
    Details
    ISSN: 1432-1106
    Keywords: Neural transplantation ; Major histocompatibility complex ; Allograft ; Rejection ; T cell subset
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using an immunocytochemical method, we examined the immunological responses of adult mice to intracerebellar syngeneic and allogeneic fetal mouse brainstem transplants (embryonic days 12–14). Syngeneic grafts and major histocompatibility complex (MHC)-compatible and non-MHC-incompatible allogeneic grafts survived well, showing no histological signs of rejection even 6 months after transplantation, and with no expression of MHC antigens being observed in any of the grafts. However, most cases of both MHC- and non-MHC-incompatible allografts showed rejection responses, such as marked neovascularization, cellular infiltration and necrosis, two weeks to one month after transplantation. In animals showing rejection, Class I MHC antigens were found on grafted neuronal tissue. An increased number of reactive astrocytes was also observed in the grafts. High levels of Class I antigen expression and prominent gliosis correlated with vigorous cellular infiltration. A quantitative analysis of T cell subsets in the animals showing rejection revealed that the L3T4/Lyt-2 ratio was 1.02±0.21 (mean ± S.D.), indicating that helper/inducer and cytotoxic/suppressor T cells appeared equally in the rejection of MHC- and non-MHC-incompatible allografts. We consider that in these experiments, the brain was not completely an immunologically privileged site, and that MHC- and non-MHC-incompatible intraparenchymal neural transplants were not shielded from host immune surveillance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00279656
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  • 2
    Electronic Resource
    Electronic Resource
    Neutronic optimization for a blanket of the laser fusion reactor, SENRI-I (1985)
    Springer
    Journal of fusion energy 4 (1985), S. 315-319 
    Details
    ISSN: 1572-9591
    Keywords: optimization ; SENRI ; blanket ; tritium ; breeding ; energy multiplication ; molten salt ; nonbreeding ; hybrid ; support ratio
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Neutronic calculations were performed to optimize the SENRI blanket in terms of energy multiplication as well as tritium breeding ratio. The blanket employs a thick (∼ 64-cm) Li layer as breeder/coolant. Three approaches were taken here to achieve the goal: (1) reduction of6Li in the lithium, (ii) replacement of the Li layer by a molten-salt (flibe) layer, and (iii) shipment of excess tritium to a nonbreeding blanket. It was found that the excess tritium produced in the SENRI blanket could be used effectively to obtain additional power by fueling a nonbreeding D-T reactor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01053361
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Nuclear design of a heliotron-H fusion power reactor (1985)
    Springer
    Journal of fusion energy 4 (1985), S. 45-55 
    Details
    ISSN: 1572-9591
    Keywords: heliotron-H ; blanket ; shield ; superconducting magnet ; tritium breeding ratio ; atomic displacement ; dose rate ; shutdown ; Monte Carlo calculation ; THIDA code system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Nuclear analysis was carried out for the heliotron-H fusion power reactor employing anl=2 helical heliotron field. The neutronics aspects examined were (a) tritium breeding capability, (b) shielding effectiveness for the superconducting magnet (SCM), and (c) induced activity after shutdown. In this reactor design of the heliotron-H, the space available for the blanket and shield is limited due to the reactor geometry. Thus, some parametric survey calculations were performed to satisfy the design requirements. The nucleonic design features of the heliotron-H are as follows. An adequate tritium breeding ratio of 1.17 is obtained when a 10-cm thick Pb neutron multiplier and a 40-cm thick Li2O breeding blanket are used. In this case, the total nuclear energy deposition is 16.10 MeV per 14.06 MeV incident neutron. The performance of the SCM is assured during ∼2 yr of continuous operation using a 20-cm thick tungsten shield. Biological dose rate behind the SCM at 1 day after shutdown is too high for hands-on maintenance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01051638
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  • 4
    Electronic Resource
    Electronic Resource
    Nuclear analysis of a laser fusion reactor, SENRI-I (1985)
    Springer
    Journal of fusion energy 4 (1985), S. 289-314 
    Details
    ISSN: 1572-9591
    Keywords: SENRI-I ; pellet ; blanket ; tritium breeding ratio ; energy deposition ; radiation damage ; activity ; streaming
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract A neutronic analysis of the laser-driven inertial-confinement fusion reactor SENRI-I is presented. Three-dimensional Monte Carlo calculations were performed to examine the effects of laser beam ports on the flux distribution, tritium breeding ratio, thermal energy deposition in the blanket, and radiation streaming. A Monte Carlo code was also used for the time-dependent radiation-damage analysis accounting for the time of the flight spread of neutrons and the results are compared to the analysis for the HIBALL design. Induced radioactivity was estimated, based on the one-dimensional transport calculation and depletion analysis. The calculated results reveal the advantages of the SENRI-I design with a thick Li layer compared to other reactor systems employing a dry-wall scheme.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01053360
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