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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Compositio mathematica 118 (1999), S. 61-102 
    ISSN: 1570-5846
    Keywords: branch locus ; covers ; curves ; discrete valuation ring ; models ; semi-stable ; simultaneous resolution.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Let K be a discrete valuation field with ring of integers O K .Letf : X ! Y be a finite morphism of curves over K. In this article, we study some possible relationships between the models over O K of X and of Y. Three such relationships are listed below. Consider a Galois cover f : X ! Y of degree prime to the characteristic of the residue field, with branch locus B. We show that if Y has semi-stable reduction over K,thenX achieves semi-stable reduction over some explicit tame extension of K.B/.WhenK is strictly henselian, we determine the minimal extension L=K with the property that X L has semi-stable reduction. Let f : X ! Y be a finite morphism, with g.Y/ 〉 2. We show that if X has a stable model X over O K ,thenY has a stable model Y over O K , and the morphism f extends to a morphism X ! Y. ! Y. Finally, given any finite morphism f : X ! Y, is it possible to choose suitable regular models X and Y of X and Y over O K such that f extends to a finite morphism X ! Y ?As wasshown by Abhyankar, the answer is negative in general. We present counterexamples in rather general situ-ations, with f a cyclic cover of any order 〉 4. On the other hand, we prove, without any hypotheses on the residual characteristic, that this extension problem has a positive solution when f is cyclic of order 2 or 3.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-4978
    Keywords: cDNA cloning ; chromosome 3q25–26.2 ; gene structure ; human latexin ; Northern hybridization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Latexin, a carboxypeptidase A inhibitor, is expressed in a cell type-specific manner in both central and peripheral nervous systems in the rat. It is used as a molecular marker for the regional specification of the neocortex. In this study, a cDNA was isolated from a human fetal brain cDNA library. The cDNA (LXN) contains an open reading frame encoding 222 amino acids. The comparison between the deduced amino acid sequences of LXN and latexins of rat and mouse revealed high sequence identity (84.2 and 84.7%, respectively). Northern blot analysis showed that LXN was expressed as a transcript of 1.3 kb in 15 out of 16 tissues examined, except in peripheral blood leukocyte. The expression levels were high in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain. It is noteworthy that the tissue distribution of human LXN differs greatly to that of its homologue in the model animal, rat latexin. In addition, the LXN gene contains at least 6 exons and spans 5.9 kb according to the genomic sequence of the clone RP11-79M21 and the gap sequence cloned in this paper. LXN was assigned to 3q25-q26.2 according to the position of the marker SHGC-35682 found adjacent to LXN gene.
    Type of Medium: Electronic Resource
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