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Digitale Medien

Intramuscular bioavailability of chlorazepate as compared to diazepam (1985)

Bertler, Å. ; Lindgren, S. ; Magnusson, J. -O. ; [weitere]

Springer

European journal of clinical pharmacology 28 (1985), S. 229-230

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Details

ISSN: 1432-1041

Schlagwort(e): diazepam ; dipotassiumchlorazepate ; benzodiazepines ; bioavailability ; administration ; healthy volunteers

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary Dipotassium chlorazepate (DPC) and diazepam (DZM) were given i.m. and i.v. to 6 healthy volunteers in doses of 20 mg (48.9 µmol) DPC and 15 mg (52.0 µmol) DZM. The interval between the injections was at least 1 week. Plasma samples were analyzed for DPC and DZM by HPLC. The bioavailability of DPC and DZM after i.m. administration, determined from computer calculated AUCs, was 1.04 and 0.85, respectively.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00609698

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