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  • 1
    Digitale Medien
    Digitale Medien
    DX centers in Si-doped AlxGa1−xAs grown by metalorganic chemical vapor deposition (1990)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 1669-1673 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Three levels corresponding to photo energies E0(=1.7 eV), E1(=1.43 eV), and E2 (=energy gap) were observed in differential photocapacitance measurements of Si-doped AlxGa1−xAs grown by metalorganic chemical vapor deposition (0.23〈x〈0.4). On the other hand, E1 and E2 were observed but E0 was not observed in the differential photoconductance measurements. Both photon energies E1 and E2 cause persistent photoconductance (PPC) and the electron concentration coincides with the concentration of Si atoms. Our results support the broken-bond model proposed by D. J. Chadi and K. J. Chang [Phys. Rev. B 39, 10063 (1989)].
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.346650
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  • 2
    Digitale Medien
    Digitale Medien
    An analytical representation of the lowest potential energy surface for the reaction O(3P)+HCl (X 1Σ+)→OH(X 2Π)+Cl(2P) (1991)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 95 (1991), S. 6421-6428 
    Details
    ISSN: 1089-7690
    Quelle: AIP Digital Archive
    Thema: Physik , Chemie und Pharmazie
    Notizen: We present a new analytical representation of the lowest 3A‘ energy surface for the reaction O(3P)+HCl(X 1Σ+)→OH(X 2Π)+Cl(2P). This surface is derived by fitting ab initio calculations, and adjustments are made to the barrier height so that rate constants derived from accurate quantum scattering calculations match the room temperature thermal rate constants. Contributions to thermal and state resolved rate constants arising from reaction on the lowest 3A' surface are also considered. Comparisons of thermal and state resolved rate constants with experiment are good except at high temperature where the 3A' contributions are significant.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.461562
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  • 3
    Digitale Medien
    Digitale Medien
    Optical measurement of crack propagation with high resolution (1993)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 64 (1993), S. 1822-1824 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: A new optical method is established to measure the crack length and its velocity in transparent crystals by utilizing the total reflection of light beam at the cleavage crack plane. The optical system is constructed by using a laser, a PIN photodiode sensor, and a wave memory. With the apparatus the crack propagation velocity can be measured at any desired position inside the specimen with a time resolution of less than 1 μs. The measurement on a cleavage crack in NaCl reveals that the maximum speed of the crack is about 800 m/s and the fluctuation of the velocity occurs prior to the arrest.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1144017
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  • 4
    Digitale Medien
    Digitale Medien
    Lichenoid skin lesions as a sign of β2-microglobulin-induced amyloidosis in a long-term haemodialysis patient (1993)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 128 (1993), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: We report a case of β2-microglobulin-induced amyloidosis. The patient was a 40-year-old man suffering from non-amyloid nephropathy, who had been treated by haemodialysis for 20 years. Lichenoid skin lesions, consisting of groups of pin-head-sized shiny papules, were present on the arms and trunk. On histological examination, amyloid deposits were present, principally in the dermal papillae, hut also around the sweat ducts and hair follicles. The amyloid displayed potassium-permanganate-resistant Congo red affinity, and green birefringence under polarized light, Immuno-histochemically, β2-microglobulin was demonstrated in the lesions, confirming that they were a manifestation of β2-microglobulin-associated amyloidosis. Skin lesions of this type have not been reported previously in β2-microglobulin-associated amyloidosis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1993.tb00266.x
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  • 5
    Digitale Medien
    Digitale Medien
    Substance P induces intracellular calcium increase and translocation of protein kinase C in epidermis (1992)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 127 (1992), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Substance P is a neuropeptide present in, and released from, peripheral C nerve endings. The presence of substance P-positive nerve fibres in the epidermis has been reported. We investigated the effect of substance P on the transmembrane signalling system of pig epidermal keratinocytes. Treatment of pig epidermis with substance P resulted in an increase in inositol 1,4,5-trisphosphate (IP3), and in intracellular free calcium. The treatment also resulted in translocation of protein kinase C from a cytosol to a membrane fraction. Substance P, however, did not affect the β-adrenergic- or histamine (H2)- adenylate cyclase responses of the epidermis. Neither forskolin-induced, nor cholera toxin-induced cyclic AMP accumulation were affected by substance P treatment. These results are consistent with the view that substance P stimulates phosphatidylinositol-4,5-bisphosphate (PIP2) hydrolysis of keratinocytes, resulting in IP3-Ca2+ and diacylglycerol-protein kinase C signal activation. Although protein kinase C is known to affect the epidermal adenylate cyclase system, no evidence for such ‘cross-talk regulation’ was detected in keratinocytes by substance P treatment.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1992.tb14872.x
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  • 6
    Digitale Medien
    Digitale Medien
    Adenylate cyclase induces intracellular calcium increase in single human epidermal keratinocytes measured by fluorescence microscopy using Fura 2-AM (1992)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 127 (1992), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Intracellular calcium ([Ca2+]i) is an important second messenger of extracellular signals to induce various cellular responses. Extracellular and intracellular Ca2+ are considered to be important for cellular differentiation and proliferation of epidermal keratinocytes. Several mechanisms which increase [Ca2+]i have been demonstrated in various tissues, but in epidermal keratinocytes these mechanisms are poorly understood. In epidermal keratinocytes the adenylate cyclase-cyclic AMP response is thought to regulate cell proliferation and differentiation. However, the series of reactions which follow the cyclic AMP response remain unknown. Beta-adrenergic agonists increase [Ca2+]i in cultured epidermal keratinocytes, and we have therefore studied whether stimulation of keratinocyte adenylate cyclase could induce [Ca2+]i increase, by using fluorescence microscopy with Fura 2-AM.Adenosine and histamine, which are known to be keratinocyte adenylate cyclase receptor agonists, induced transient [Ca2+]i increase, as did epinephrine. In addition, forskolin, a direct adenylate cyclase activator, and dibutylyl-cyclic AMP also induced an increase in [Ca2+]i. In a calcium-free medium epinephrine, adenosine, histamine and dibutylyl-cyclic AMP induced an increase in [Ca2+]i. These results suggest that cyclic AMP in human epidermal keratinocytes regulates [Ca2+]i, which is released from intracellular stores.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1992.tb14871.x
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  • 7
    Digitale Medien
    Digitale Medien
    Immunohistochemical analysis of human skin using antispectrin and anti-β-fodrin antibodies (1990)
    Springer
    Archives of dermatological research 282 (1990), S. 274-277 
    Details
    ISSN: 1432-069X
    Schlagwort(e): Spectrin ; Fodrin ; Membrane skeleton ; Keratinocytes
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00371651
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  • 8
    Digitale Medien
    Digitale Medien
    Use of dihydrorhodamine 123 for detecting intracellular generation of peroxides upon UV irradiation in epidermal keratinocytes (1992)
    Springer
    Archives of dermatological research 284 (1992), S. 114-116 
    Details
    ISSN: 1432-069X
    Schlagwort(e): Peroxide ; Keratinocyte ; UV ; Dihydrorhodamine ; Hydrogen peroxide
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00373382
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  • 9
    Digitale Medien
    Digitale Medien
    Adenylate cyclase induces intracellular Ca2+ increase in single human epidermal keratinocytes of the epidermal sheet as measured by digital imaging microscopy using Fura 2-AM (1991)
    Springer
    Archives of dermatological research 283 (1991), S. 91-95 
    Details
    ISSN: 1432-069X
    Schlagwort(e): Intracellular free calcium ; Human epidermis ; Beta-adrenergic receptor ; Adenylate cyclase ; Fura 2 ; Digital imaging microscopy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Intracellular Ca2+ ([Ca2+]i) is thought to act as a second messenger of transmembrane signalling systems. However, no measurement of [Ca2+]i has been made in intact epidermal keratinocytes. We have developed a method for measuring [Ca2+]i in human keratinocytes from pure epidermal sheet by the application of digital imaging fluorescence microscopy with the use of Fura 2-AM. Normal human pure epidermal sheets were obtained by dispase treatment. Epinephrine and salbutamol induced transient [Ca2+]i increases. Propranolol, a Β-antagonist, inhibited this response, while prazosin and yohimbine (alpha1- and alpha2-antagonists, respectively) did not affect the response. Histamine and adenosine, also receptor agonists of the epidermal adenylate cyclase system, induced a similar [Ca2+]i increase, as did forskolin, a direct activator of adenylate cyclase. These data coincide with those previously presented for cultured human epidermal keratinocytes, and reveal that adenylate cyclase activation induces an increase of [Ca2+]i in intact epidermal cells. This technique enables the kinetics of [Ca2+]i in various skin disorders to be investigated.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00371615
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  • 10
    Digitale Medien
    Digitale Medien
    Presence and localization of proteins immunologically related to erythrocyte protein 4.1 in human skin (1991)
    Springer
    Histochemistry and cell biology 95 (1991), S. 549-554 
    Details
    ISSN: 1432-119X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Analogues of human erythrocyte protein 4.1 have been examined in the human skin by immunochemical techniques using anti-human erythrocyte protein 4.1 antibodies. Immunoblot analysis revealed that human epidermis contains 4.1-like proteins of 80 kDa and 78 kDa that cross react with anti-protein 4.1 antibodies. Analysis with immunofluorescence microscopy revealed that the plasma membrane of the human epidermal keratinocyte was stained intensively in the basal cells, whereas spinous cells were moderately stained. It is noted that eccrine sweat gland cells and ductal cells were also stained in the peripheral cytoplasma. Taken together, these results demonstrate that 4.1-like proteins are present in human epidermal keratinocytes, eccrine sweat gland cells and ductal cells. The present findings enable us to suggest that a membrane skeletal protein lattice might exist in these cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00266740
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