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  • 1
    Digitale Medien
    Digitale Medien
    Alpha-1-Mikroglobulin in Urin und Serum bei Proteinurie und Niereninsuffizienz (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 711-717 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Alpha-1-microglobulin ; Beta-2-microglobulin ; Proteinuria ; Renal insufficiency
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Alpha-1-microglobulin (alpha-1-m) is a low molecular weight glycoprotein (mw 25–33 KD) that is filtered through the glomeruli and reabsorbed in the proximal parts of the renal tubules where it is catabolized. Normal ranges were established for alpha-1-m (100 healthy controls) in serum (20–42 mg/l) and urine (3.5–8 mg/l). Alpha-1-m was then measured in 341 urine samples whose protein pattern had been classified as “pathologic” and “normal” according to microelectrophoresis. Increased alpha-1-m concentrations were found in 266 out of 280 pathologic urines (5% false negative) and in 3 out of 61 normal urines (4% false positive). Beta-2-microglobulin (beta-2-m), total protein or protein test strips showed a poorer correlation to the electrophoretic results. Measurement of alpha-1-m is, therefore, the most sensitive of these methods for the detection of proteinuria. In 90 patients with low molecular weight proteinuria and either with or without renal insufficiency alpha-1-m concentrations were determined in both urine and serum. While all patients had elevated urinary alpha-1-m concentrations, increased serum values were only found in renal insufficiency (Ccrea〈100 ml/min). Independently of these results, we were also able to establish that increased alpha-1-m levels are found at decreased glomerular filtration rates (Ccrea 〈70 ml/min). Pathologic alpha-1-m concentrations therefore only allow the conclusion of isolated tubular impairment when the GFR is greater than 70 ml/min. Data from 350 patients with various renal and hypertensive diseases showed that serum alpha-1-m is a more sensitive indicator of renal insufficiency, even in the so-called “creatinine blind” range (60–100 ml/min) of the GFR than either creatinine or beta-2-m.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01733115
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  • 2
    Digitale Medien
    Digitale Medien
    Effects of various HTK solution regimens on proteinuria after renal transplantation in dogs (1995)
    Springer
    Urological research 23 (1995), S. 351-360 
    Details
    ISSN: 1434-0879
    Schlagwort(e): Proteinuria ; Kidney transplantation ; Kidney preservation ; HTK solution
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Investigations were carried out by means of an autologous, heterotopic model for kidney transplantation applied to dogs. Duration of cold ischemia was 48 h. Four experimental groups were arranged. During the first 20 min following revitalization of the transplanted kidney, group 1 (HTK solution/80 cm perfusion height) showed a significant glomerular and tubular malfunction. In group 2 (HTK solution/120 cm perfusion height), only four urinary proteins with molecular weights of 25 kDa, 67 kDa, 100 kDa and 〉100 kDa were found. The excretion of higher molecular proteins receded over the 20-min period of observation. In both group 3 (HTK/aspartate solution) and group 4 (HTK/tryptophan solution) the quantity of excreted glomerular and tubular protein was well above that of group 2. As opposed to the “Tryptophan” group, a complete restoration of renal function was observed in the “Aspartate” group after 4 weeks. In general, the “standard” HTK protective solution delivered with 120 cm perfusion pressure gave the most favorable results, with the lowest levels of proteinuria and a satisfactory recovery of renal function after revitalization.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00300027
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  • 3
    Digitale Medien
    Digitale Medien
    Urinary protein electrophoresis profile in normal and hypertensive pregnancies (1989)
    Springer
    Archives of gynecology and obstetrics 246 (1989), S. 97-105 
    Details
    ISSN: 1432-0711
    Schlagwort(e): Hypertensive pregnancy ; Proteinuria ; SDS-polyacrylamide gel electrophoresis ; Western blot ; Tamm-Horsfall glycoprotein
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary By using of modified urine preparation and a highly sensitive SDS-polyacrylamide gel electrophoresis (SDS-PAGE) we determined the urinary protein profile in 21 healthy males, 25 healthy females, 64 patients with uncomplicated pregnancy and 110 hypertensive pregnant women. The urinary protein patterns were similar in controls and in women with a normal pregnancy. There were no increase in the number of protein bands from the 1st trimester to term, and the electrophoresis pattern did not change in the postpartum period. In both groups, an intensively stained protein band with an apparent molecular weight of 105 kD was detected. The 105 kD band was significantly reduced or completely absent in 91 (83%) out of 110 hypertensive pregnant women. The urinary protein electrophoresis profile correlated significantly with the severity of the disease. The 105 kD band disappeared just before or simultaneously with the onset of clinical symptoms in 18 out of 32 hypertensive pregnant women followed throughout pregnancy. Postpartum the 105 kD in urine reappeared at 2 to 14 days after delivery in 49 of the 53 patients. Using a silver staining and Western blot, the 105 kD band was identified as Tamm-Horsfall protein, which is identical to the immunosuppressive glycoprotein uromodulin. The findings in the SDS-PAGE may reflect a transitory tubular dysfunction in cases of pre-eclampsia, which is usually reversible after delivery. The results of our study support the hypothesis of an immunological basis for this disorder.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00934126
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  • 4
    Digitale Medien
    Digitale Medien
    Design rules for the wallcooled hydrothermal burner (WHB) (1997)
    Weinheim : Wiley-Blackwell
    Chemical Engineering & Technology - CET 20 (1997), S. 208-211 
    Details
    ISSN: 0930-7516
    Schlagwort(e): Chemistry ; Industrial Chemistry and Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The results of a process analysis and an experimental exploratory study of supercritical water oxidation (SCWO) show that elements of combustion technology are suitable to overcome the technical problems of SCWO. The Film Cooled Hydrothermal Burner (FCHB) which operates at 25 MPa up to 2000 K in the reaction zone keeping wall temperature under stress at 300 to 400 K shows further development potential of the Wallcooled Hydrothermal Burner (WHB) concept for SCWO, a still promising waste treatment process.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ceat.270200309
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  • 5
    Digitale Medien
    Digitale Medien
    Abscheidung leitender und nichtleitender Hartstoffschichten auf metallischen und keramischen Werkstoffen mittels Hochfrequenz-Plasma-CVD (1993)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 24 (1993), S. 392-396 
    Details
    ISSN: 0933-5137
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Maschinenbau
    Beschreibung / Inhaltsverzeichnis: Deposition of conductive and nonconductive hard coatings on metallic and ceramic materials by RF-PA-CVDConductive titanium nitride and nonconductive aluminium oxide layers were deposited on conductive and nonconductive substrates by a RF-PA-CVD process. The influence of substrate material, pressure, plasma power and the components of the gas mixture on the layer properties was investigated.TiN coatings with a homogeneous structure could be deposited by using TiCl4 as precursor. The properties of the layer are strongly influenced by the substrate material. An increasing pressure causes a faster deposition rate and a higher chlorine content. A lower chlorine content and at the same time a faster deposition rate can be achieved by increasing the r.f. power.Aluminium and aluminium oxide layers could be deposited on steel and Si3N4 substrates by using AlCl3 as precursor in dependence on the CO2 content in gas mixture. Higher CO2 content facilitates the deposition of aluminium oxide.
    Notizen: Mit einem Hochfrequenz-Plasma-CVD-Verfahren wurden elektrisch leitende TiN-Schichten und nichtleitende Al2O3-Schichten auf leitende wie nichtleitende Substrate aufgebracht. Der Einfluß des Grundwerkstoffes sowie der Versuchsparameter Druck, Plasmaleistung und Prozeßgaszusammensetzung auf die Schichteigenschaften wurde untersucht.Mit TiCl4 als Precursor konnten TiN-Schichten mit einem homogenen Schichtaufbau hergestellt werden. Die Schichteigenschaften sind deutlich vom Grundwerkstoff abhängig. Eine Steigerung des Systemdruckes hat einen Anstieg der Abscheiderate und des Chlorgehaltes zur Folge. Eine Erhöhung der Plasmaleistung führt zur Senkung des Chlorgehaltes bei leicht gesteigerter Abscheiderate.Mit AlCl3 als Spendermedium konnten in Abhängigkeit vom CO2-Prozeßgasanteil Aluminium- oder Aluminiumoxidschichten auf Stahl- und Si3N4-Substraten abgeschieden werden. Höhere CO2-Anteile begünstigen die Abscheidung von Aluminiumoxid.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/mawe.19930241108
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  • 6
    Digitale Medien
    Digitale Medien
    Letters to the Editor (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 1271-1276 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690170548
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  • 7
    Digitale Medien
    Digitale Medien
    Heat transfer and frost formation inside a liquid nitrogen-cooled tube (1966)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 12 (1966), S. 1190-1195 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: An experimental study was undertaken of simultaneous heat transfer and frost deposition inside a liquid nitrogen-cooled tube for a range of humidities and Reynolds numbers. The data indicate that diffusion of water vapor within the frost layer caused the frost density and thermal conductivity to increase with time. The increase was so great that the heat transfer rate became constant even while frost continued to accumulate. In a separate study the thermal conductivities of frosts formed on a cryogenic surface were measured and found to be lower than values near the freezing point of water.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690120626
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  • 8
    Digitale Medien
    Digitale Medien
    Effect of the concentration of DODMAC and 1-decanol on the behavior of reverse micelles in the extraction of amino acids (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 46 (1995), S. 343-350 
    Details
    ISSN: 0006-3592
    Schlagwort(e): reverse micelles ; decanol ; amino acid extraction ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The concentrations of dioctyldimethyl ammonium chloride (DODMAC) and 1-decanol in isooctane needed to form reverse micelles by phase contact have been determined. The behavior of these reverse micelles in the extraction of aspartic acid, glutamic acid, and threonine was studied by analyzing all of the ionic species in the aqueous phase. The amino acid is extracted from the aqueous phase by exchanging with the Cl- counterions of DODMAC in the reverse micelles. The ionic species in the reverse micelles tend toward their undissociated states as the water uptake by the reverse micelles decreases. The effect of 1-decanol on the extraction of the amino acids with two negative charges is due to the change in the water uptake of the reverse micelles. The concentration of DODMAC has no effect on the ion exchange of the amino acid with one negative charge with the Cl- counterions of DODMAC in the reverse micelles. Higher molar ratios of decanol to DODMAC favor the selective separation of amino acids with different charge numbers. © 1995 John Wiley & Sons, Inc.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bit.260460407
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  • 9
    Digitale Medien
    Digitale Medien
    Chemie-Erfindungen und ihr Schutz. Von F. Hirsch. VCH Verlagsgesellschaft, Weinheim - Basel - Cambridge - New York 1987. IX, 179 S., 1 Abb., brosch., DM 98,- (1988)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 60 (1988), S. 574-574 
    Details
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/cite.330600722
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  • 10
    Digitale Medien
    Digitale Medien
    Maßstabsübertragung von Suspendiervorgängen in vollbewehrten Rührbehältern im turbulenten Strömungsbereich (1995)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 67 (1995), S. 1133-1134 
    Details
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/cite.330670974
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