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  • Artikel: DFG Deutsche Nationallizenzen  (30)
  • 1980-1984  (20)
  • 1975-1979  (9)
  • 1960-1964  (1)
  • 11
    Digitale Medien
    Digitale Medien
    EFFECTS OF GLUCAGON ON PANCREATIC SECRETION IN THE DOG (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 3 (1976), S. 0 
    Details
    ISSN: 1440-1681
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: 1. The effects of glucagon on the secretion of pancreatic juice were investigated using blood-perfused canine pancreas preparations.2. Intravenous administration of glucagon (3–30 μg/kg) to the donor dog elicited a dose-dependent increase in pancreatic secretion. Intra-arterial administration of glucagon (10–100 μg) into the perfused pancreas also elicited increased secretion.3. There were slight increases in amylase concentration of the pancreatic juice with the largest doses of glucagon given by either route.4. Glucagon-induced secretion was not modified by treatment with phentolamine, propranolol, atropine, guanethidine, tetrodotoxin, haloperidol, prostaglandin F2a or calcitonin.5. The results suggest that glucagon acts directly on the exocrine cells of the canine pancreas.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-1681.1976.tb00591.x
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  • 12
    Digitale Medien
    Digitale Medien
    EFFECTS OF CALCITONIN ON THE SECRETION OF PANCREATIC JUICE INDUCED BY DOPAMINE, SECRETIN AND PANCREOZYMIN (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 3 (1976), S. 0 
    Details
    ISSN: 1440-1681
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: 1. Effects of calcitonin on dopamine-, secretin- and pancreozymin-induced pancreatic secretion were investigated in the isolated blood-perfused canine pancreas.2. The volume of pancreatic secretion induced by pancreozymin given intra-arterially (i.a.) was decreased by an i.a. infusion of 1 u/min of calcitonin, but that induced by dopamine or secretin given i.a. was not affected by calcitonin treatment.3. Amylase concentration in pancreatic juice either in spontaneous secretion in the resting state or in that of stimulated secretion by pancreozymin was decreased approximately 30% by calcitonin treatment, but amylase concentration in pancreatic juice induced by dopamine or secretin was not affected by calcitonin treatment.4. Calcitonin had no effect on bicarbonate concentration in pancreatic juice stimulated by these secretagogues.5. Calcium concentration in pancreatic juice in the resting state was reduced about 36% by calcitonin treatment. Calcitonin caused a decrease in a calcium concentration in the pancreozymin-induced secretion, but did not cause any change in the dopamine- or secretin-induced one.6. These results suggest that calcitonin may affect the secretory mechanism of the acinar cells but not that of the ductular cells, and that the acinar cells are active even in the resting state.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-1681.1976.tb00600.x
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  • 13
    Digitale Medien
    Digitale Medien
    The effect of corticosteroids, dapsone and gold upon plasminogen activator synthesis and secretion by human epidermal cells cultured with pemphigus antibody (1984)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 110 (1984), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Human epidermal cells were cultured with pemphigus antibody in the presence of hydrocortisone, methlprednisolone sodium succinate, dapsone and gold. Hydrocortisone and methylprednisolone reduced the production of the enzyme plasminogen activator but dapsone and gold had no effect. These results support the hypothesis that corticosteroids have dual effects on pemphigus through inhibition of plasminogen activator production by epidermal cells and suppression of pemphigus antibody production by B lymphocytes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1984.tb04634.x
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  • 14
    Digitale Medien
    Digitale Medien
    Molecular size of secreted and cell-associated plasminogen activators from cultured epidermal cells (1983)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 109 (1983), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The molecular sizes of secreted and cell-associated plasminogen activators from four cultured cell types were determined using an SDS-PAGE technique in which plasminogen and casein were included during polymerization of the polyacrylamide gel. The major bands of plasminogen activators secreted by human neonatal epidermal cells, human adult epidermal cells and transformed human squamous cells migrated the same distance as the high molecular weight band of authentic urokinase, indicating that the apparent molecular weight of these plasminogen activators was approximately 55,000 daltons. Plasminogen activator extracted from normal adult human epidertnis also migrated with this major band of plasminogen activator, and a minor higher molecular weight band was also detected. In contrast, plasminogen activators secreted by transformed mouse squamous cells migrated between the high molecular weight band (∼ 55K) and the low molecular weight band of urokinase (∼ 32K), indicating that plasminogen activators of mouse epidermal cells differ from those of human epidermal cells. The mobility of the major bands of plasminogen activators detected in cell lysates of the four cell types was identical to that of secreted plasminogen activators.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1983.tb03986.x
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  • 15
    Digitale Medien
    Digitale Medien
    Anodic characteristics of amorphous ternary palladium-phosphorus alloys containing ruthenium, rhodium, iridium, or platinum in a hot concentrated sodium chloride solution (1983)
    Springer
    Journal of applied electrochemistry 13 (1983), S. 295-306 
    Details
    ISSN: 1572-8838
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Amorphous ternary palladium-based alloys containing platinum group metals as an additional element were prepared by rapid quenching from the molten state and their anodic characteristics were investigated in a 4 mol dm−3 NaCl solution of pH 4 and 80° C. The amorphous alloys containing sufficient quantities of rhodium, platinum or iridium were passivated by anodic polarization and their corrosion rates at high current densities in the chlorine evolution region were extremely low. This fact was attributed to the formation of a highly protective passive film due to both the transformation to the amorphous structure and the addition of rhodium, platinum or indium. The electrocatalytic activities for chlorine evolution of amorphous alloys were higher than those of pure platinum group metals except palladium. In particular, the amorphous Pd41Ir40P19 alloy had the desired stable, high electrocatalytic activity for chlorine evolution and the high overvoltage for oxygen evolution.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00941601
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  • 16
    Digitale Medien
    Digitale Medien
    The chemoreflex induced by intraarterial injection of Aza-azepinophenothiazine, veratridine and bradykinin into femoral and brachial arteries of innervated and divided limbs of a dog (1964)
    Springer
    Cellular and molecular life sciences 20 (1964), S. 394-396 
    Details
    ISSN: 1420-9071
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Zusammenfassung Reflektorische Blutdrucksteigerung wurde durch intraarterielle Injektion von Tetrahydro-azaazepinophenothiazin und Veratridin am Präparat des innervierten Hinterbeins vom Hund hervorgerufen. Während kleine Dosen von Bradykinin nur leichte Blutdrucksenkung verursacht, führen grössere Dosen zu nachhaltigem Blutdruckanstieg. Bei Abhäuten des Hinterbeinpräparates unterblieb der Primäreffekt.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02147987
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  • 17
    Digitale Medien
    Digitale Medien
    Occurrence of tetrodotoxin in the starfishAstropecten latespinosus (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 1395-1396 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Astropecten latespinosus ; starfish ; tetrodotoxin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary A toxin causing paralysis was detected in the starfishAstropecten latespinosus. The toxin was purified by a method consisting of charcoal treatment and chromatography on CM-Sephadex C-25 and Bio-Rex 70. The toxin was identified as tetrodotoxin by its behavior in thin-layer chromatography and electrophoresis and its1H-NMR spectrum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01951908
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  • 18
    Digitale Medien
    Digitale Medien
    Inhibition of brain enolases by acrylamide and its related compounds in vitro, and the structure-activity relationship (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 971-972 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Rat brain ; Enolase ; acrylamide ; acrylamide derivatives ; neurotoxicity ; structure-activity relationship
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Acrylamide and its related compounds inhibited brain enolases in vitro independently of their neurotoxicity. The inhibitory potency was a function of the binding constants of the compounds for phenylalanine. The binding constant for tryptophan was higher in neurotoxic compounds than in non-neurotoxic ones.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01946464
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  • 19
    Digitale Medien
    Digitale Medien
    Linkages between chromophore and apoprotein in the biliverdin-protein of the scales of big blue parrotfish, Scarus gibbus Rüppell (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 583-584 
    Details
    ISSN: 1420-9071
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary On the basis of the amino acid composition of the chromophore peptides, it can be assumed that Asp, Ser and 1/2 Cys are located near the biliverdin chromophore. Experiments for splitting of the chromophore lead us to expect a thioether bond in the linkages between biliverdin and apoprotein.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01946509
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  • 20
    Digitale Medien
    Digitale Medien
    Immunohistochemical demonstration of the localization of corticotropin releasing factor-containing neurons in the hypothalamus of mammals including primates (1982)
    Springer
    Anatomy and embryology 165 (1982), S. 303-313 
    Details
    ISSN: 1432-0568
    Schlagwort(e): CRF neurons ; Hypothalamus ; Immunohistochemistry ; PAP ; Mammals
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The presence of the CRF-containing neurons in the hypothalamus was investigated in four different species (cats, dogs, pigs, and monkeys) by the peroxidase-antiperoxidase technique using specific anti-serum to CRF. In all animals examined, CRF-containing perikarya were found mainly in the paraventricular and supraoptic nuclei, and a small number of the immunoreactive cells were observed in the accessory supraoptic nucleus and the lateral hypothalamic area. The size of the CRF-containing perikarya ranged from 20–35 μm in diameter. These findings suggest that the magnocellular paraventricular and supraoptic nuclei are the center not only of the classical neurosecretory system for the production of the posterior lobe hormones, but also that of the CRF neuronal system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00305569
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