Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Electronic Resource
    Electronic Resource
    Polymorphism of uridine monophosphate kinase: population study in Japanese and phenotyping in bloodstains (1990)
    Springer
    International journal of legal medicine 104 (1990), S. 13-16 
    Details
    ISSN: 1437-1596
    Keywords: Polymorphism ; Red cell enzyme ; UMPK ; Population study ; Bloodstains ; Polymorphismus ; Erythrozyten-Enzym ; UMPK ; Bevölkerungsstudie ; Blutspuren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Der Polymorphismus der Uridin Monophosphat Kinase (UMPK) wurde in einer Stichprobe von 677 nicht-verwandten Personen aus Japan untersucht. Folgende Allel-Frequenzen wurden ermittelt: UMPK*1 = 0,9594, UMPK*2 = 0,0406. Phänotypisierung war auch an Blutspuren möglich, welche eine Woche bei 37°C, 4 Wochen bei Zimmertemperatur oder mehr als 10 Wochen bei 4°C gelagert worden sind. Das UMPK System kann eine nützliche Ergänzung in der forensischen Blutspurenkunde sein.
    Notes: Summary The polymorphism of UMPK was investigated in 677 unrelated Japanese individuals. The allele frequencies were estimated to be UMPK*1 = 0.9594 and UMPK*2 = 0.0406. Our sample was devoid of the UMPK*3 allele. Phenotyping was also possible from bloodstains stored at 37°C for up to 1 week, at room temperature for up to 4 weeks and at 4°C over 10 weeks. The UMPK system can be a useful supplement for the mediocolegal grouping of bloodstains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01816477
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Polymorphism of coagulation factor XIII B subunit: Further occurrence of FXIIIB*15 in Japanese and phenotyping in bloodstains (1992)
    Springer
    International journal of legal medicine 104 (1992), S. 317-319 
    Details
    ISSN: 1437-1596
    Keywords: Polymorphism FXIIIB ; Population genetics ; Bloodstains ; Polymorphismus FXIIIB ; Populationsgenetik ; Blutspuren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Der Polymorphismus des FXIIIB wurde bei 555 unverwandten Japanern mit Hilfe der isoelektrischen Fokussierung und anschließendem Immunoblotting untersucht. Fünf allgemein vorkommende Phänotypen und die seltene Variante FXIIIB 15-3 wurden beobachtet. Die Allel-Frequenzen waren FXIIIB = 0,3063, FXIIIB2 = 0,0162, FXIIIB3 = 0,6766 und FXIIIB15 = 0,0009. Die Bestimmung der Phänotypen war auch an Blutspuren mit folgenden Lagerungsbedingungen möglich: Bei 37°C über einen Zeitraum bis zu 4 Monate, bei Raumtemperatur und bei 4°C länger als 6 Monate. Das FXIIIB-System kann einen neuen, aussagekräftigen genetischen Marker für gerichtsmedizinische Blutspurenuntersuchungen darstellen.
    Notes: Summary The polymorphism of FXIIIB was investigated in 555 unrelated Japanese individuals using isoelectric focusing and immunoblotting. Five common phenotypes and a rare variant type FXIIIB 15-3 were observed. The allele frequencies were FXIIIB*1 = 0.3063, FXIIIB*2 = 0.0162, FXIIIB*3 = 0.6766 and FXIIIB*15 = 0.0009. Phenotyping was also possible from bloodstains stored at 37°C for up to 4 months and from bloodstains stored at room temperature and at 4°C for over 6 months. The FXIIIB system can provide a new powerful genetic marker for the medicolegal grouping of bloodstains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01369549
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    Crystallographic Texture Changes of Oriented Ethylene-Vinylalcohol Copolymer Films on Rolling (1994)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 157-162 (May 1994), p. 727-732 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/00/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.157-162.727.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    Expression of collagen species in a cartilaginous tumor derived from a human osteogenic sarcoma (1994)
    Springer
    Calcified tissue international 54 (1994), S. 516-520 
    Details
    ISSN: 1432-0827
    Keywords: Chondrosarcoma ; Nude mice ; Hybridization ; Collagen ; mRNAs ; Transplanted tumor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract We have succeeded in transplanting human osteogenic sarcoma into nude mice. Morphologically, the transplanted tumor is chondrosarcoma and manifests calcification, but not ossification. This tumor is thought to be an excellent model for studying the process of morbid endochondral calcification. In this study, we have used in situ hybridization to examine expression of collagen type I, II, and III mRNAs in this tumor. In situ hybridization was carried out using biotinylated DNA probes. Hybridized probes were detected using a streptavidin-biotin-alkaline phosphatease reagent. The results showed that collagen type I and II mRNAs were produced by cells of the transplanted tumor. Collagen type I mRNA was chiefly localized in the marginal region of the tumor. Collagen type II mRNA, which was predominantly found in the premineralized region of the transplanted tumor, gradually decreased toward the mineralized region. Collagen type III mRNA was not expressed in the transplanted tumor. These results suggest that the character of progenitor chondrogenic cells might be transferred to the transplanted tumor, and that the tumor cells may change the expression of collagen genes with the differentiation or maturation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00334335
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    Growth hormone deficiency of hypothalamic origin in septo-optic dysplasia (1990)
    Springer
    European journal of pediatrics 150 (1990), S. 30-33 
    Details
    ISSN: 1432-1076
    Keywords: Septo-optic dysplasia ; Hypopituitarism ; Growth hormone releasing hormone ; Infantile spasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hypothalamic pituitary function and growth hormone releasing hormone (GHRH) loading tests in two children with septo-optic dysplasia (SOD) revealed isolated GH deficiency in one and deficiencies of growth hormone, adrenocorticotropic hormone and antidiuretic hormone in the other. Secretion of GH was elicited in the first patient by single i.v. bolus administration of GHRH and after repetitive i.v. infusions of GHRH in the second. With these results we confirmed that the hypopituitarism in our patients with SOD was of hypothalamic origin. Both patients also had infantile spasms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01959475
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    Characterization of cell fusion in XC cells induced bySuncus murinus mammary tumor virus (1990)
    Springer
    Archives of virology 115 (1990), S. 267-276 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Syncytium formation in a rat tumor cell line (XC) induced bySuncus murinus mammary tumor virus (Sm-MTV) was studied. Multinucleate giant cells containing 20–30 nuclei were formed in a monolayer of XC cells by cocultivation with X-ray-irradiated Sm-MTV producing cells (Sm-MT-1). By fluorescent antibody staining, Sm-MTV antigens were demonstrated in the cytoplasm of syncytia, and budding particles and intracytoplasmic A particles were found in syncytial giant cells by electron microscopy. Cell-free supernatant of Sm-MT-1 was capable of inducing syncytia at a much lower incidence than cocultivation of Sm-MT-1 cells. Syncytium formation was completely inhibited when anti-Sm-MTV bovine serum was added to the coculture medium. Pretreatment of XC cells with actinomycin-D caused a partial reduction of Sm-MTV-induced cell fusion, but syncytium formation did occur at a reduced rate even when cellular RNA synthesis was completely inhibited. Dexamethasone increased virus production in Sm-MT-1 cells, resulting in the enhancement of Sm-MTV mediated syncytium formation. Sm-MTV was found to have a unique characteristic of cell fusion activity on XC cells with striking enhancement by dexamethasone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01310535
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    Human T-cell leukemia virus type 1 protease protein expressed inEscherichia coli possesses aspartic proteinase activity (1993)
    Springer
    Archives of virology 128 (1993), S. 195-210 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We amplified the human T-cell leukemia virus type 1 (HTLV-1) protease gene fragment by polymerase chain reaction (PCR) and cloned it into a pUC plasmid vector. DNA sequencing data of the protease gene fragment indicated that it contained an open reading frame capable of encoding the active HTLV-1 protease. To express a fusion protein of β-galactosidase linked with the HTLV-1 protease inEscherichia coli, a plasmid DNA was constructed by inserting the HTLV-1 protease gene DNA into a procaryotic expression vector, pUEX2, consisting of alacZ gene directed by a λ phage Pr promoter and designated pUEX-pro. By Western blot analysis using anti-β-galactosidase antibody, a bigger molecular size band than that of the control β-galactosidase molecule was observed inE. coli cells transformed with pUEX-pro but not with control pUEX 2, suggesting that the particular fusion protein was successfully expressed. This recombinant protease protein in theE. coli cell lysate was demonstrated to be able to cleave the decapeptide substrates composed of amino acid sequences containing proteolytic cleavage sites in the HTLV-1gag precursor polyprotein. Thegag precursor polyprotein expressed in the mammalian cells by the recombinant vaccinia virus system was also expectedly cleaved by this enzyme. Significant inhibition of this protease activity by pepstatin A, an aspartic proteinase-specific inhibitor, confirms that HTLV-1 protease is a member of the aspartic proteinase group as suggested previously. Since the crude lysate without purification is utilized sufficiently as a native HTLV-1 protease reagent, this protease preparation is easily applicable to the large scale screening of HTLV-1 protease inhibitors for the treatment of diseases caused by HTLV-1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01309434
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Molecular changes in protoplast-derived rice plants (1990)
    Springer
    Molecular genetics and genomics 223 (1990), S. 324-328 
    Details
    ISSN: 1617-4623
    Keywords: Rice ; Protoplast ; RFLP ; Methylation ; Polymorphism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary To determine whether regeneration of rice plants from protoplast culture induces DNA polymorphisms, progeny plants from direct regenerants of such cultures were examined for restriction fragment length polymorphisms (RFLP analysis). Significantly increased levels of DNA polymorphism were found compared with those in non-tissue culture control plants. Analysis with gene sequences representative of different functional domains, revealed that such polymorphisms are apparently widespread and not associated with any particular region. Analysis by comparative digestion with both methylation-sensitive and insensitive restriction enzymes revealed that methylation changes cannot be regarded as a major factor in the induction of these DNA polymorphisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00265070
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    Evaluation of hyperechoic liver tumors in MHTS (1993)
    Springer
    Journal of medical systems 17 (1993), S. 127-132 
    Details
    ISSN: 1573-689X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hepatocellular carcinoma (HCC) shares only a small proportion of hyperechoic liver tumors detected in MHTS and mimics hemangioma on ultrasonography (US). The precise diagnosis of HCC is hence difficult in MHTS, but presence or absence of underlying chronic liver disease and serum alfa-fetoprotein (AFP) titer might provide useful informations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00996936
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    Preconditioning of the heart by repeated stunning: attenuation of post-ischemic dysfunction (1992)
    Springer
    Basic research in cardiology 87 (1992), S. 128-138 
    Details
    ISSN: 1435-1803
    Keywords: Heart ; stunning ; ischemia ; reperfusion ; infarctsize ; adaptation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of repetitive brief periods of coronary occlusion on subsequent prolonged ischemic insult was studied using a swine heart model. Four 5-min episodes of left anterior descending coronary artery (LAD) occlusion, each separated by 10 min of reperfusion, did not affect any of the regional or global myocardial functions examined, except that the level of adenosine triphosphate (ATP) dropped to some extent. Sixty minutes of LAD occlusion following four repeated stunnings further reduced the ATP level, but this reduction was significantly lower compared to nonstunned control. Myocardial global functions were not affected significantly by prolonged ischemic insult. Segment shortening (SS) was reduced comparably in both control and stunned groups. However, SS improved significantly during subsequent reperfusion in the stunned group compared to control. The experimental group also demonstrated reduced infarct size and an area of risk compared to nonstunned control. These results indicate that repeated stunning prior to irreversible ischemic insult can attenuate ischemic injury and post-ischemic dysfunction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00801960
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...