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  • 11
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Colposcopic, histological and cytological characteristics of 168 consecutive patients attending a colposcopy clinic were reviewed. A group of patients demonstrated a cluster of histological features previously related to possible human papilloma virus infection of cervical epithelium, including particularly koilocytosis, double nucleation and dyskeratosis. These patients had a significantly greater occurrence of colposcopic ‘finger-like’ lesion outline and colposcopic impression of warty change, but not of other specific colposcopic features. Over two-thirds of patients with histological warty features did not show these colposcopic changes. Cytological changes previously related to warty lesions did not occur commonly, and appeared to underestimate the histological occurrence of such changes. Histological changes considered to represent CIN were uncommon in patients who said that they had begun sexual activity less than 10 years ago, whereas patients with warty characteristics on histology showed no such bias.
    Type of Medium: Electronic Resource
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  • 12
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Of 420 patients attending a colposcopy clinic 204 were treated with outpatient cryosurgery for cervical intraepithelial neoplasia. It was possible to assess a definite outcome of therapy in 159 patients, and the lesion was successfully eradicated in 87% of them. Treatment failure appeared to be more common in patients of high parity, when the lesion extended into the cervical canal, and in those patients with large lesions. Failure appeared to be unrelated to patient age and to the histological grade of the lesion. In subsequent pregnancies utero-cervical function was preserved.
    Type of Medium: Electronic Resource
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  • 13
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Mice were injected for 1–2 months daily with 10 mg immunoglobulin G (IgG) from four patients with Lambert-Eaton myasthenic syndrome (LEMS); control mice were injected with pooled human IgG from normal donors. Gastrocnemius muscles were homogenised for the assay of acetylcholine (ACh), choline acetyltrans-ferase (ChAT), and cholinesterase (ChE). The ACh, ChAT, and ChE contents of gastrocnemius muscles from “LEMS mice” were about the same as the control values, which were 180 pmol, 40 nmol * h−1 (37°C), and 15 μmol * h−1 (37°C), respectively. Hemidiaphragms were treated with an irreversible ChE inhibitor (Soman) and incubated at 20°C for estimation of ACh release. Resting ACh release from experimental muscles was reduced by about 25% (P2 〈 0.05) and the release evoked by 3 s−1 nervous stimulation by 50% (P2 〈 0.05). On the other hand, 50 mM KCl-induced transmitter release was not abnormal in LEMS mice. The findings indicate that IgG antibody from patients with LEMS may bind to nerve terminal determinants that are involved in quantal and nonquantal ACh release.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 817-827 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The radiation-enhanced sublimation of different types of graphite was measured during H+ or D+ irradiation, by line-of-sight quadrupole mass spectroscopy; the quadrupole mass spectrometer was modified to block the transmission of reflected beam particles. The radiation-enhanced sublimation yield depends on both the type and orientation of the graphite; the highest yields (∼0.2 C/D at 1800 K for 1 keV D+) are associated with the most dense and most ordered graphite (pyrolytic graphite, HPG99). The yield at 400 K temperature is of the order of 10−3 C/D for 1 keV D+, more than one order of magnitude lower than the physical sputtering yield. The measured radiation-enhanced sublimation yields are in good agreement with model calculations. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 77 (1995), S. 66-86 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new model has been developed for hydrogen retention and trapping in and release from graphite. Two different regions in the graphite with different hydrogen transport and trapping behaviors are distinguished, the bulk region within, and the surface region on graphite crystallites. The model incorporates new experimental results related to atom diffusion and recombination on inner surfaces. Recombination is explained from a fundamental viewpoint by linking it to diffusion using a classical expression. The model is applied to a number of reemission and thermal desorption experiments, in particular, the reemission of hydrogen atoms during irradiation with energetic hydrogen ions and the formation of HD during irradiation with H+ and D+ or during thermal desorption of graphite that was preimplanted with H+ and D+ ions with different energies. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 710-718 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Because of the large amount of kinetic energy and mass needed for efficient production of K-shell emission from moderate atomic number z-pinch plasmas (Z(approximately-greater-than)22), moderate Z experiments performed in the near future will likely take place at relatively low implosion velocities or low-η values, where η is defined as the ratio of the maximum kinetic energy per ion generated prior to stagnation to the minimum energy per ion, Emin, needed to instantly heat and to ionize a plasma into the K shell upon stagnation of the pinch. Since there has been no systematic theoretical or experimental investigations of K-shell yield scaling with mass and atomic number in the low-η regime η∼1–3, in anticipation of such future experiments, we report on the results of our theoretical investigation into this regime. In particular aluminum, argon, titanium, and krypton plasmas were studied using a 1D radiation hydrodynamics model that uses enhanced transport coefficients to phenomenologically attain the stagnation conditions of experimental z-pinches. The results of this study have identified the following important effects: low-η plasmas remain in an inefficient mass2 (or current4) scaling regime at much higher masses than predicted by our earlier work, which was based on η(approximately-greater-than)3.7 calculations. Thus, more energy than predicted by the earlier scaling laws will apparently be needed to obtain significant amounts of, for example, krypton K-shell emission. In addition, lags in ionization times become important increasingly with the Z of the plasma and adversely affect K-shell emission. The physics responsible for these time dependent effects and how they will influence the design of future experiments are discussed. ©1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 73 (1998), S. 58-60 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Imaging of the surface of a cleaved Bi2Sr2CaCu2O8+δ (BSCCO) single crystal with a scanning tunneling microscope reveals a series of repeating terraces, whose separations are then used to identify the atomic planes which are exposed. On each of the exposed planes, the incommensurate modulation is also clearly resolved with atomic resolution. The measured separations between the terraces lead to the deduction that any atomic layer can be exposed by mechanical cleavage of BSCCO. We, therefore, suggest that the identity of atomic planes, and the direction of tunneling, should always be taken into consideration when interpreting tunneling spectra obtained on such cleaved BSCCO crystals. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 84 (1998), S. 1655-1669 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A methane erosion yield model has been developed using the principal atomistic reactions outlined by Küppers and co-workers [eg., A. Horn, A. Schenk, J. Biener, B. Winter, C. Lutterloh, M. Wittmann, and J. Küppers, Chem. Phys. Lett. 231, 193 (1994)] with additional terms to account for the energy of the incident particles, namely, kinetic ejection and damage deposition. Furthermore, modifications were made to the previous models by using distributed activation energies for methyl and hydrogen release as well as an activated Eley-Rideal abstraction process. Fitting of this model to experimentally measured methane yield data shows excellent agreement, except for low energy (≤25 eV) impact at temperatures above ∼800 K. We have provided a sound physical basis for the behavior of the free fitting parameters and conclude that most of the processes associated with low-energy impact on pyrolytic graphite leading to methane production have been incorporated. Possible extensions of the model to include heavy hydrocarbons and total chemical erosion yields are also discussed. Due to the lack of comprehensive experimental data on the flux dependence of hydrocarbon erosion, the flux dependence of the fitting parameters could not be explored and so the effect of flux density requires further modeling considerations. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 70 (1999), S. 1459-1463 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We describe the design and development of a scanning tunneling microscope (STM) which can operate at temperatures down to 240 mK and in magnetic fields up to 7 T with high spatial and energy resolution. The compact and rigid STM head is mounted directly on a low vibration, single shot, 3He refrigerator. This refrigerator can be operated at its base temperature continuously for several days before the 3He needs to be recondensed. The system is equipped with a sample transport manipulator from room temperature, and a cleavage device at low temperature, so that the cryogenic ultrahigh vacuum condition inside the cryostat can be utilized. A superconducting magnet provides a magnetic field of up to 7 T at the sample along the STM tip direction. Test results have shown that, at the base temperature, this instrument has better than 0.5 pm z-direction resolution in imaging mode, and better than 20 μV energy resolution in spectroscopy mode. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 90 (1983), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Plasma progesterone levels were measured in three groups of untreated women. (1) Nine women with follicle rupture, proved by laparotomy or laparoscopy, had values of ≥40 nmol/l on days 18–24 (days −10—5 from the next period); thus a value of 〈40 nmol/1 should not be taken as evidence of ovulation. (2) Nineteen healthy women with normal menstrual histories had hormone assays on alternate days during one cycle. In five of them all values were 〈38 nmol/1. (3) Forty women had a single progesterone assay on days 20–29 of a conceptual cycle. Eight of them had a level 〈40 nmol/l. Ovulation had certainly occurred in all of them, but it is difficult to assess whether the sample timing was optimal since there was no following menstrual period. Progesterone levels in drug-induced conceptual cycles were in general higher than those in spontaneous pregnancy cycles. Women with luteinization of the unruptured follicle frequently had values of 〉40 nmol/l. Conversely, a secretory endometrium was not uncommon in cycles with values of 〈38 nmol/l.
    Type of Medium: Electronic Resource
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