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  • 11
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, induced, as do also monoclotaline, etc., a marked arterial and arteriolar hypertrophy of the lung of young Wistar rats a month after a single s. c. injection of 50–80 mg/kg. Cor pulmonale with leftward shift of the ventricular septum was also noted.
    Type of Medium: Electronic Resource
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  • 12
    ISSN: 1432-0533
    Keywords: Bunina bodies ; Anterior horn cells ; Amyotrophic lateral sclerosis ; Cytoplasmic laminar bodies ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Light and electron microscopic studies were made on the anterior horn cells in a case of amyotrophic lateral sclerosis. Eosinophilic inclusions of Bunina type were observed almost selectively in the motor neurons of spinal cord, as well as of brain stem, at the light microscopic level. Fine structural study revealed the presence of two types of cytoplasmic inclusions. The first, mainly corresponding to the light microscopic inclusions, were homogeneous, electron-dense, round- or oval-shaped bodies with vesicular or tubular rims and ribosome particles, about 2–5 μ in diameter, which contained filaments or other cytoplasmic components in the clear areas within them. The second were lamellar structures (laminated cytoplasmic bodies, Morales) which appeared to be originating from endoplasmic reticulum. There was no distinct transition in these two types of inclusions and the relationship to each other is not clear. The significance of Bunina body is unknown, but some manifestation of a primary disorder, e.g., protein metabolism, rather than a secondary degenerative change in the motor neurons in amyotorophic lateral sclerosis.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 34 (1978), S. 988-989 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Freeze-dried samples were used for the determination of glutamate decarboxylase activity in discrete preoptic and hypothalamic nuclei. The activity showed marked regional variation in distribution.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 216 (1977), S. 79-89 
    ISSN: 1432-1459
    Keywords: Normal muscle spindle ; Histochemistry ; Intrafusal fiber types ; Fusimotor endings ; Fusisensory endings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden normale Skeletmuskelspindeln von Menschen histochemisch untersucht. 1. Histochemisch wurden vier Muskelfasertypen der intrafusalen Fasern — Bag I fiber, Bag II fiber, Chain I fiber und Chain II fiber — von ATPase-Aktivität klassifiziert. Bei der NADH-Tetrazolium-Reduktase wurden zwei Muskelfasertypen an intrafusalen Fasern — Bag I fiber und Bag II fiber — beobachtet. 2. Drei Typen der motorischen Endplatte — en plaque Endplatte, en grappe Endplatte und diffuse Endplatte — wurden an Muskelspindeln von Cholinesterase klassifiziert. 3. Zwei Typen der sensorischen Nervenenden — primär-sensorisches Nervenende und sekundärsensorisches Nervenende — wurden an Muskelspindeln mit NADH-Tetrazolium-Reduktase und elektronmiktroskopisch beobachtet.
    Notes: Summary Normal muscle spindles of human skeletal muscle were studied histochemically. 1) Four histochemical types of intrafusal muscle fibers were classified by ATPase stain: Bag I fiber, Bag II fiber, Chain I fiber and Chain II fiber. Moreover, two types of nuclear bag fibers were classified by NADH Tetrazolium Reductase stain and PAS stain: Bag I fiber and Bag II fiber. 2) Three kinds of fusimotor endings were verified by the cholinesterase technic: en plaque, en grappe and diffuse endings. 3) Two kinds of fusisensory endings were verified by NADH TR stain and also electron-microscopically: primary and secondary sensory endings.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 219 (1978), S. 261-271 
    ISSN: 1432-1459
    Keywords: Fusimotor endings ; Acetylcholinesterase ; Parkinsonism ; Motor neuron disease ; Myasthenia ; Muscle spindles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In Serienschnitten wurden die motorischen Endplatten der intrafusalen Muskelfasern in Muskelspindeln von Patienten mit Parkinsonismus, myatrophischer Lateralsklerose und Myasthenia gravis mittels Acetylcholinesterasereaktion untersucht. Beim Parkinsonismus erschienen die diffusen Endigungen, von welchen angenommen wird, daß sie die Endigungen des Gammafasersystemes darstellen, nennenswert verbreitert, während die en-plaque- und en-grappe-Endigungen atrophisch erschienen. In den Fällen von myatrophischer Lateralsklerose erwiesen sich en-plaque- und en-grappe-Endigungen, von welchen angenommen wird, daß sie zu den Betaneuronen und den dynamischen Gammafasern gehören, als ausgesprochen atrophisch. Die diffusen Endigungen allerdings waren normal. Bei Myasthenia gravis und dem myasthenischen Syndrom von Eaton-Lambert zeigten en-plaque- und engrappe-Endigungen Atrophien, während einzig die diffusen Endigungen ausgespart blieben. Es wird die Bedeutung dieser Veränderungen diskutiert.
    Notes: Summary Pathological changes of the fusimotor endings in parkinsonism, motor neuron disease and myasthenia were examined by the acetylcholinesterase technic on serial sections. In parkinsonism, the diffuse endings, which are thought to be supplied by the static gamma nerve fibers, showed remarkable enlargement, while en plaque and en grappe endings were atrophic. In motor neuron disease, en plaque and en grappe endings, which are thought to be innervated by the beta nerve fibers and dynamic gamma nerve fibers respectively, revealed marked atrophy. However the diffuse endings were normal. In myasthenia gravis and myasthenic syndrome (Eaton-Lambert syndrome), en plaque and en grappe endings were atrophic, though only the diffuse endings were spared. The significance of these changes in the fusimotor endings is discussed.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Euphytica 28 (1979), S. 697-704 
    ISSN: 1573-5060
    Keywords: Oryza sativa ; rice ; gamma-radiation ; temperature ; mutation frequency ; heading date
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Dry seeds of rice, Oryza sativa L., containing about 13 percent moisture, were exposed to 60Co gamma raysat extremely low temperature (−196°C). M1 damage on survival rate, seedling height and seed set were found to become much smaller in the cooling treatment than in the not-cooled control. Chlorophyll and heading date mutation frequencies in the M2 generation were not affected by the decreased M1 damage caused by the cooling treatment, and the mutation frequencies could be significantly increased by applying higher doses combined with the cooling treatment. Frequency of sterile or semi-sterile mutants in the M2 generation was found to be significantly lower in the cooling treatment than in the not-cooled control. It is assumed from the experimental results that extremely low temperatures during irradiation could reduce the amount of physiological damage and gross chromosome aberrations. This results in an increased efficiency of producing minute deletions and/or point mutations.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Journal of engineering mathematics 10 (1976), S. 95-105 
    ISSN: 1573-2703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Technology
    Notes: Summary Thermo-mechanico-electromagnetic coupled waves propagating in a linear isotropic thermo-elastic dielectric material are theoretically investigated, in case an external magnetic field is applied to the material. Here the constitutive equations derived from the Clausius-Duhem inequality and Vernotte's heat conduction law are adopted. There are three types of coupled waves: the predominantly electromagnetic wave, the predominantly mechanical transverse wave and the predominantly thermo-mechanical longitudinal wave. The first and second waves have no thermal coupling. The third wave has thermal coupling and its propagation velocity and attenuation constant are perturbed by the external magnetic field.
    Type of Medium: Electronic Resource
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