Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Electronic Resource
    Electronic Resource
    Differentiation and migration of endoderm in the rat and mouse at implantationThis study was supported by grants HD 04962 and HD 10342 from the National Institue of Child Health and Human Development. (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 190 (1978), S. 65-77 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The initial differentiation of endoderm at the time of onset of implantation, and the subsequent rapid differentiation of visceral and parietal endoderm were studied in the rat and mouse. Transmission electron microscopy illustrates the reorientation and loosening of embryonic cell mass cells during implantation, as well as cytological evidence that endoderm cells have differentiated. Using scanning electron microscopy, parietal endoderm consists of individual stellate cells with numerous peripheral branching filopodia. As these cells migrate abembryonically, the rest of the embryonic cell mass becomes recom-pacted. The visceral endoderm proliferates and forms a columnar epithelium which has the cytological characteristic of an absorptive epithelium and is able to ingest exogenous proteins. Thus, by 24 hours after implantation, the two endo-dermal derivatives have assumed widely diverse shapes and different types of associations and rates of replication, and are probably performing different functions.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091900107
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Mouse uterine glands during the delayed and induced implantation periodsThis study was supported by Grants HD 04962 and HD 10342 from the National Institute of Child Health and Human Development and by National Institute of Health Traineeship Grant GM 021025 to the Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri. (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 190 (1978), S. 271-283 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Mouse uterine glandular epithelium during the lactationally delayed implantation period and after estradiol induction of implantation was investigated using light and electron microscopy. During the delayed implantation period the lumen of this simple tubular gland is narrowed. The glandular epithelial cells have a well developed Golgi complex lateral to the nucleus, and numerous cisternae of smooth and rough endoplasmic reticula (RER) and many electron lucent apical vesicles of sizes up to 0.2 μm in diameter near the luminal border. The basal region contains lipid droplets and dispersed, irregular cisternae of RER. Twenty-four hours after the administration of 17β-estradiol the glandular lumina become dilated but the luminal content does not stain with azure B. Ultrastructurally the glandular cells are not remarkably different from those seen during the delay period. However, by 48 hours after estradiol administration the glandular lumina are not only dilated but filled with material which stains intensely with azure B and is ultrastructurally dense and homogeneous. The apical region of the glandular cells contains granules up to 0.4 μm in diameter composed of electron dense material similar in density to that seen in the glandular lumen. In addition, the Golgi complex has assumed a position apical to the nucleus, and the basal RER has an increased number and more orderly arrangement of cisternae.The changes seen in the uterine glands after the induction of implantation during the delay period are apparently indicative of increased secretory activity of the glandular epithelia. However, the contribution of the glands to the changes in uterine fluid composition has yet to be established.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091900210
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    Trophoblast-decidual cell interactions and establishment of maternal blood circulation in the parietal yolk sac placenta of the rat (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 217 (1987), S. 203-219 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Implantation sites from rats were studied on days 6, 7, and 8 of pregnancy to determine the sequence of events in the formation of blood spaces in the trophoblast that is part of the parietal wall of the yolk sac placenta and to determine how trophoblast gains access to maternal blood. The maternal blood flowing through these spaces is the source of nutrients that reach the embryo via the visceral endoderm. Tissues were prepared for light microscopy, scanning electron microscopy, and transmission electron microscopy. Trophoblast blood spaces are derived from the lateral intercellular spaces of trophoblast cells and are present in a collapsed condition until day 8, when maternal vessels are tapped by trophoblast. These spaces than contain circulating maternal blood, and trophoblast cells reflect adaptations for metabolic exchange including thinning of trophoblast covering Reichert's membrane and the appearance of numerous fenestrations, with and without diaphragms, in the areas where trophoblast is attenuated. Between days 6 and 7 decidual cells appear to form a barrier between the maternal circulation and trophoblast. On day 7, however, decidual cell processes penetrate the residual uterine luminal epithelial basal lamina, and then the decidual cells that are juxtaposed to trophoblast undergo degradative changes that resemble apoptosis. There is condensation of cytoplasmic contents, fragmentation of the cells, and phagocytosis of the fragments by trophoblast. Some decidual cells are interposed between endothelial cells in the walls of maternal vessels as early as day 7. Trophoblast may gain access to the maternal vessels by replacing decidual cells or by direct imposition of trophoblast cell processes between endothelial cells.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1092170213
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    Cytology of the fetal zone of the adrenal gland of the armadilloSupported by National Science Foundation grant GB-2476 and NICHD grant 5T1-HD-21. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 154 (1966), S. 807-821 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of the adrenal gland of the fetal armadillo was examined by electron microscopy to determine whether or not there were two cell types in the parenchyma of the fetal zone, as suggested by examination by light microscopy, and whether any of the cells of this zone had the cytological features associated with steroid production.Two cell types were found. One cell type is composed of large cells situated in clusters and containing a relative paucity of organelles. The other cell type is composed of smaller, eosinophilic, PAS positive cells, situated primarily in a reticular pattern around the blood vessels. This second cell type has numerous spherical mitochondria with tubular cristae and an extensive tubular agranular endoplasmic reticulum. It is concluded that this latter cell type is responsible for the steroid production reported by other authors. Both of the cell types of the fetal zone appear to be derived from the original mesenchymal blastema of the adrenal gland.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091540409
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    An electron microscope study of the rat endometrium during delayed implantationSupported by National Science Foundation grant G-21829. During the course of this investigation, the senior author was a National Science Foundation Graduate Fellow. (1964)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 148 (1964), S. 177-195 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The luminal and glandular epithelia of the rat uterus during delayed implantation have been studied with the electron microscope. The tall columnar cells of the luminal epithelium are characterized by a distinct zonation of organelles. On the free surface there are short microvilli and occasional cytoplasmic extrusions, with terminal bars joining adjacent cells at their apical margins. Beneath the free surface are numerous pinocytotic vesicles and mitochondria. Above the nucleus are a prominent Golgi apparatus with large dilated vacuoles, and numerous dense inclusion bodies. Large clusters of lipid droplets and aggregations of mitochondria occupy the basal zone of the cell.The apical portion of the gland cell has fewer pinocytotic vesicles and the Golgi is smaller than in the luminal epithelial cells. Dense bodies are numerous above the nucleus. The basal portion of the gland cell is devoid of lipid, but there are often one or more enlarged mitochondria. Although a dense PAS+ substance fills the lumina of the glands, there is no obvious evidence of secretory activity in the glands during delay.The relationships of the epithelia to the environment of the blastocysts during delay is discussed.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091480208
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    The placenta of the four-eyed opossum (philander opossum)Philander opossum)Supported by grant 5 RO1 HD02613 from the National Institute of Child Health and Human Development. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 431-449 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The placental membranes of the four-eyed opossum were studied by light and electron microscopy. The individual fetuses in each uterus were surrounded by amnion, had allantoic sacs of approximately the same size as each fetus, and were situated in a common yolk sac cavity. The extent of the choriovitelline placenta was marked by a prominent sinus terminalis, and at this margin there was a region where the trophoblast cells penetrated folds of the endometrium. Elsewhere the choriovitelline placenta was closely applied to the uterine epithelium along most of its surface, but the microvilli of the two epithelia did not interdigitate. Numerous inclusion bodies were seen in the trophoblast of both the choriovitelline and bilaminar omphalopleure portions of the placenta, but the aggregates were larger in the latter. The endoderm cells of the choriovitelline placenta had extensive endoplasmic reticulum and numerous mitochondria, but did not have conspicuous absorption canaliculi.Placentation in the four-eyed opossum appears to represent a progressive advance over that of the Virginia opossum both in confluence of the yolk sacs of the fetuses and in having a region of penetration of the maternal endometrium by trophoblast.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650311
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    The implantation chamber, blastocyst and blastocyst imprint of the rat: A scanning electron microscope studyThis study was supported in part by Grant HD-04962 from the National Institute of Child Health and Human Development. Initial acquisition of the scanning electron microscope used was made possible by Health Sciences Advancement Award 5 SO4 RR 06115. (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 182 (1975), S. 137-149 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Splitting the uterus longitudinally through implantation sites makes it possible to obtain access to blastocysts and implantation chambers during stages of implantation of the blastocyst in the rat. On the afternoon of day 5 of pregnancy, blastocysts lie in a shallow antimesometrial depression and tend to fall free of the uterus when the chamber is opened. On day 6, blastocysts are oriented in a mesometrial-antimesometrial plane, occupy a distinct implantation chamber, and tend to adhere to one side or the other of the uterus, leaving an imprint on the contralateral side. After about noon of day 6, some of the blastocysts split in half laterally, and by day 7 all blastocysts which are exposed are split. In addition to demonstrating increased adhesion of blastocyst to uterine epithelium, the procedure clearly shows the progressive elongation of the implantation chamber. The embryonic cell mass is specifically oriented on day 6, and is clasped but not distorted, whereas the abembryonic trophoblast is slightly compressed and indented by the uterine epithelium. The microvilli of the uterine epithelium within the imprint become progressively flattened when compared to the microvilli of the implantation chamber outside of the imprint. The method provides a means of gaining direct access to the surface of uterine epithelium precisely where it has been in association with the blastocyst not only for scanning electron microscopy but also for studies of the properties of the surface constituents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091820202
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Serum maintains the fertilizability of mouse oocytes matured in vitro by preventing hardening of the zona pellucida (1986)
    New York, NY : Wiley-Blackwell
    Gamete Research 15 (1986), S. 115-122 
    Details
    ISSN: 0148-7280
    Keywords: cumulus cells ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The effects of serum and cumulus cells during oocyte maturation in vitro on subsequent oocyte fertilizability and zona pellucida digestability have been examined. Cumulus cell-enclosed oocytes were cultured 15-16 hours in medium containing bovine serum albumin plus varying concentrations of fetal bovine serum (FBS). When the serum concentration was decreased incrementally from 5% to 0%, resistance to chymotrypsin digestion increased accordingly in a dose-dependent manner. The zona pellucida digestion time for oocytes matured in serum-free medium was increased nearly 500% above that for control oocytes matured in 5% FBS. Also, fertilization was decreased as serum concentration was lowered; the fertilization percentage for oocytes matured in serum-free serum was reduced by over 90%. This loss of fertilizability was correlated with an absence of sperm within the vitellus following insemination of matured ova. Increasing the serum concentration from 5% to 10% had no effect on fertilization or zona pellucida digestion time. Serum deprivation, even for a short period of time, at the onset of culture significantly reduced the fertilizability of cumulus cell-enclosed oocytes and increased the zona pellucida digestion time. Removal of serum after oocyte maturation in vitro had little effect. The presence of an intact cumulus oophorus during maturation in vitro was important in the maintenance of fertilizability and zona digestability. These data support the idea that serum deprivation and/or removal of the cumulus cells during oocyte maturation in vitro results in an alteration of the zona pellucida that is manifested as an increased resistance to proteolytic digestion and sperm penetration.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120150203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    Developmental capacity of mouse oocytes that undergo maturation in vitro: Effect of the hormonal state of the oocyte donor (1989)
    New York, NY : Wiley-Blackwell
    Gamete Research 24 (1989), S. 81-92 
    Details
    ISSN: 0148-7280
    Keywords: oocyte maturation ; fertilization ; preimplantation development ; gonadotropins ; mouse ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In a previous study, it was shown that cumulus cell-enclosed germinal vesicle (GV)-stage oocytes, isolated from pregnant mares' serum gonadotropin (PMSG)-primed immature (22-24 day old) mice and that underwent spontaneous maturation in vitro, exhibited frequencies of embryonic development similar to oocytes stimulated to mature and ovulate in vivo by administration of gonadotropins [Schroeder AC, Eppig JJ, (1984) Dev Biol 102:493-497]. In the present study, the effect of the hormonal state of the oocyte donor on the capacity of in vitro matured oocytes to be fertilized and undergo pre- and post-implantation development was explored further. Oocytes were isolated at the GV-stage from the following groups of mice: 1) unprimed immature mice; 2) adult cycling mice; 3) unprimed Snell dwarf (dw) mice that have undetectable levels of growth hormone (GH), prolactin, and thyroid-stimulating hormone (TSH); and 4) primed and unprimed hypogonadal (hpg) mice that have undetectable levels of circulating gonadotropins. Oocytes maturing in vitro after isolation from normal unprimed immature or adult mice at all stages of the estrous cycle acquired full developmental capacity. GV-stage oocytes isolated from dwarf mice showed embryonic development equivalent to normal ( + /?) littermate controls. Therefore, GH, TSH, or prolactin are not required during oogencsis in vivo to promote the acquisition of competence to complete embryogenesis after maturation in vitro. Oocytes from hypogonadal mice had a much reduced capacity for preimplantation development when compared with normal littermates. Administration of PMSG to the hypogonadal mice significantly increased the developmental capacity of oocytes that underwent maturation in vitro. Gonadotropins, therefore, have a beneficial effect on the oocytc's capacity for embryonic development.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120240111
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    Archaebacteria: The road to the universal ancestor (1986)
    New York, NY : Wiley-Blackwell
    BioEssays 5 (1986), S. 75-78 
    Details
    ISSN: 0265-9247
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Living forms are now divided into three primary kingdoms, eubacteria, archaebacteria and eukaryotes. The archaebacteria demonstrate a blending of eubacterial and eukaryotic features and cast new perspectives on the nature of the universal ancestor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bies.950050207
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...