ISSN:
1573-4927
Keywords:
mice
;
erythrocyte
;
glucose 6-phosphate dehydrogenase
;
nicotinamideadenine dinucleotide phosphate
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract NADP measurements in erythrocytes of eight inbred strains of mice showed a correlation between low NADP and low erythrocytic G6PD levels. In vitro heat inactivation tests indicated that the NADP differences found could explain the previously demonstrated lability of G6PD in the erythrocytes of the low G6PD activity strain, C57L/J. Breeding experiments suggested a common genetic control of erythrocytic NADP levels and G6PD activity in crosses between intermediate and low strains, but an effect of sex and other variables, as yet unidentified, precluded a strong demonstration of unitary genetic control.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00486617
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