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  • 11
    Electronic Resource
    Electronic Resource
    Anaesthesia for laryngoscopy (1968)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 23 (1968), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1968.tb00040.x
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  • 12
    Electronic Resource
    Electronic Resource
    Cadmium delays growth hormone expression during rainbow trout development (2001)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 59 (2001), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Growth hormone (GH) mRNAs were first detected in rainbow trout Oncorhynchus mykiss during organogenesis (stage 29) within a control group while GH expression in cadmium exposed embryos was not detected until a later organogenic period (stage 31). GH transcripts were subsequently detected at all further developmental stages analysed within both treatment groups. These included hatching (stage 32), larval development (stages 33, 34, 35 and 36) and first feeding (stage 37). These results confirm that the GH axis is functional during early rainbow trout development and demonstrate an in vivo endocrine disrupting capacity at the molecular level for cadmium in teleosts. This is of particular relevance to freshwater habitats as heavy metal induced endocrine disruption may be a contributing factor in the decline of salmonid populations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.2001.tb00168.x
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  • 13
    Electronic Resource
    Electronic Resource
    THE FREQUENCY RESPONSE MODEL OF THERMAL STRIPING FOR CYLINDRICAL GEOMETRIES (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 20 (1997), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— The random temperature fluctuation produced by the incomplete mixing of hot and cold fluid streams passing over the surface of a component or structure is known as thermal striping. This phenomenon may cause thermal fatigue to occur. It is of particular concern in various types of nuclear reactors, for rapid shut-downs of hot plant and in thermal stratification. A computer code, “TBL”, is a design tool which has been developed to assess thermal striping damage in plates. This model is further developed in this paper to assess such damage in cylindrical components. A recent, universal weight function method is examined and incorporated into TBL. Good comparisons are found between TBL and finite element results for a sinusoidally varying temperature-time-striping history. Potential thermal striping damage is assessed for a cylindrical component of material typically found in the above-core region of a fast reactor under a random temperature-time-striping history.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1997.tb01531.x
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  • 14
    Electronic Resource
    Electronic Resource
    Simplified Microhydrogenation Apparatus (1941)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 13 (1941), S. 841-843 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/i560099a037
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  • 15
    Electronic Resource
    Electronic Resource
    Free and Bound Water in Elastic and Non-Elastic Gels (1932)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 36 (1932), S. 387-436 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j150331a026
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  • 16
    Electronic Resource
    Electronic Resource
    Speed of injection and spread of bupivacaine in the epidural space (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 42 (1987), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Speed of injection of bupivacaine was assessed in 73 women who received epidural analgesia in labour. Rapid injection was shown to produce quicker onset of epidural block and more reliable perineal anaesthesia than slow injection, but there was no difference in the final extent of the block.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1987.tb02990.x
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  • 17
    Electronic Resource
    Electronic Resource
    Chloroform anaesthesia in Liverpool (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 38 (1983), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The introduction of chloroform into anaesthesia is described, together with an account of the parts played by Simpson and Waldie and their connexions with Liverpool. An account of the first chloroform anaesthetics administered in Liverpool is also given; David Waldie, who suggested the use of chloroform, was one of the administrators at the first demonstration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1983.tb14072.x
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  • 18
    Electronic Resource
    Electronic Resource
    Grass pollen content of the air in the Bristol Channel region in 1976 (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 7 (1977), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The grass pollen content of the air at four sites bordering the Bristol Channel (at Bristol, Cardiff, Penarth and Penmaen) was studied. The trap at Penmaen was situated at an official climatological station which provided the meteorological data used in the surveys. Although at certain times large differences could be seen between the concentrations of grass pollen at the different sites, overall the findings for the four sites were similar. Changes in the atmospheric pollen concentration related to variations in meteorological conditions. At the peak of the season high concentrations of grass pollen persisted throughout the night.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1977.tb01468.x
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  • 19
    Electronic Resource
    Electronic Resource
    Detection of Pityrosporum orbiculare reactive T cells from skin and blood in atopic dermatitis and characterization of their cytokine profiles (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 26 (1996), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Atopic dermatitis (AD) is associated with increased levels of serum igE. and T-helper (Th) cells are thought to a play role in the pathogenesis. Individuals with AD often develop IgE antibodies against the yeast Pityrosporum orhiculare. a member of the normal cutaneous flora.Objective The role of P. orbiculare in atopic dermatitis was investigated by examining the T-cell reactivity for P. orbiculare.Methods Freshly isolated peripheral blood monoruclear cells (PBMC) were isolated from 10 AD patients with serum IgE antibodies against P. orbiculare, and from six healthy controls. The proliferative response after P. orbiculare stimulation, measured by [3H]thymidine incorporation, was examined in the PBMC and in T-cell clones (TCC) obtained from skin and blood of one patient. The cytokine profile of the TCC was determined by enzyme-linked immunosorhent assay (ELISA). radioimmunoassay (RIA) and reverse transcriptase-polymerase chain reaction (RT-PCR) following challenge with either P. orbiculare extract or anti-CD3 antibodies and phytohaemag-glutinin.Results The PBMC response to P. orbiculare was significantly higher in the AD patients than in the control group (P 〈 0.05). Twenty-nine out of 36 tested TCC derived from one responding patient were reactive for P. orhiculare. The clones were CD2+ and CD4+, except for one CD8+ blood clone. A majority of the TCC derived from lesional skin showed a Th2- or Th2/Th0-like cytokine profile. A co-expression of interIeukin-5 (IL-5) mRNA and II-13 mRNA was detected in five out of six P. orhicularc-reative clones analysed for their cytokinc gene expression with RT-PCR.Conclusion Our data suggest that P. orhiculare can induce a T-cell response in AD patients. The Th2-like profile of P. orbiculare-reactive TCC derived from lesional skin indicates that P. orhiculare may play a role in maintaining IgE-mediated skin inflammation in AD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1996.tb00526.x
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  • 20
    Electronic Resource
    Electronic Resource
    Myeloperoxidase and interleukin-8 levels in chronic sinusitis (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 27 (1997), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We have recetitly phenotyped inflammation iti tion-infectious allergic and non-allergic chronic maxillary sinusitis using sinus biopsies and lavage fluids. In this first paper, we have concentrated our work on the eosinophil, T cell, mast cell and macrophage infiltrates. However, many unresolved questions remain and particularly the role of neutrophils needed to be addressed. In the present study, we focused on the neutrophilic inflammation: myeloperoxidase (MPO) and interleukin-8 (IL-8) were measured by immunoassays and neutrophils were enumerated by conventional staining in the sinus lavage fluids of 16 patients with chronic sinusitis and six control subjects. Both MPO and IL-8 levels were significantly higher in patients than in controls (P 〈 0.01 and 0.005, respectively). There was a significant correlation between MPO levels and neutrophil numbers, and between MPO and IL-8 levels in the sinus lavage fluid (P 〈 0.0001, Spearman rank correlation). The presence of high levels of IL-8 in the lavage fluids of patients suffering from chronic sinusitis, levels which correlate with those of MPO, suggests that this cytokine may activate neutrophils in this chronic disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1997.tb01195.x
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