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  • 11
    Electronic Resource
    Electronic Resource
    Characterization of the chromatin structure in the upstream region of the chicken alpha-globin gene domain (1994)
    Springer
    Molecular genetics and genomics 242 (1994), S. 649-652 
    Details
    ISSN: 1617-4623
    Keywords: α-Globin domain ; Hypersensitive sites ; Locus control region ; Chromatin structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The distribution of DNase I hypersensitive sites upstream of the chicken α-globin gene cluster was studied. A group of hypersensitive sites with a complex pattern of tissue specificity, including erythroid-specific elements, was found at a distance of 11.5–14.5 kb upstream of the π gene, the first gene in the cluster. The observations indicate that this area, located upstream of the block of AT-rich sequences and MAR sites (at −8 kb) and upstream of the site of permanent DNA attachment to the nuclear matrix (−3 kb), still belongs to the domain of the α-globin genes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00283418
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    Paper (German National Licenses)
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  • 12
    Electronic Resource
    Electronic Resource
    The sequence-specific nuclear matrix binding factor F6 is a chicken GATA-like protein (1993)
    Springer
    Molecular genetics and genomics 238 (1993), S. 309-314 
    Details
    ISSN: 1617-4623
    Keywords: Nuclear matrix attachment ; GATA ; Chicken globin genes ; DNA-binding protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The sequence-specific DNA-binding protein factor F6, which binds upstream of the cluster of the chicken α-globin genes, has previously been found to interact with a DNA fragment containing a replication origin and a nuclear matrix binding site. This protein has been partially characterized. Based on its molecular weight and binding affinity, F6 belongs to a family of GATA proteins, the chicken equivalent of transcription factor NFE-1. An oligonucleotide including the binding site for F6 competes for binding of the above-mentioned DNA fragment to the nuclear matrix. This indicates an involvement of this protein in the interaction between DNA and the nuclear matrix.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00291988
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    Paper (German National Licenses)
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  • 13
    Electronic Resource
    Electronic Resource
    Organization of specific DNA sequence elements in the region of the replication origin and matrix attachment site in the chicken α-globin gene domain (1992)
    Springer
    Molecular genetics and genomics 235 (1992), S. 381-388 
    Details
    ISSN: 1617-4623
    Keywords: Bent DNA ; DNA melting pattern ; Replication origin ; Matrix attachment site ; Globin genes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The distribution of specific DNA sequence elements in a 2.9 kb HindIII fragment of chicken DNA containing the replication origin and the upstream matrix attachment site (MAR) of the α-globin gene domain was investigated. The fragment was shown to contain a CR1-type repetitive element and two stably bent DNA sequences. One of them colocalizes with the previously described MAR element and with the recognition site for a proliferating-cell-specific, DNA-binding protein. The melting pattern of a set of subfragments of the region proved to be non random. No correlation between the distribution of readily melting sequences and bent DNA was found. The possible importance of curved, low-melting and repetitive DNA sequences for the organization of the upstream boundary of the α-globin gene domain and the function of the replication origin is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00279384
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    Paper (German National Licenses)
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  • 14
    Electronic Resource
    Electronic Resource
    DNA interactions with the nuclear matrix and spatial organization of replication and transcription (1987)
    New York, NY : Wiley-Blackwell
    BioEssays 6 (1987), S. 19-23 
    Details
    ISSN: 0265-9247
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Analysis of the DNA sequence associated with the nuclear matrix has made it possible to identify several types of DNA matrix association. Permanent attachment sites are detected in both transcriptionally active and inactive nuclei. Furthermore, replication origins have been shown to be permanently attached to the nuclear matrix. In transcriptionally active nuclei, expressed genes are also associated with the nuclear matrix. Finally, a special group of attachment sites is described; these sites are believed to maintain the fixed positions of individual chromosomes in interphase nuclei.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bies.950060106
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    Paper (German National Licenses)
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