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  • 11
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 75 (1968), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 12
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Entomology 37 (1992), S. 349-374 
    ISSN: 0066-4170
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 13
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Psychology 8 (1957), S. 113-138 
    ISSN: 0066-4308
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Psychologie
    Materialart: Digitale Medien
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  • 14
    ISSN: 1752-1688
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geographie
    Notizen: : A deep water-resource and stratigraphic test well near the center of Nantucket Island, about 40 miles (64 km) off the New England Coast, has encountered freshwater at greater depth than predicted by the Ghyben-Herzberg principle. An uppermost lens of fresh-water, which occupies relatively permeable glacial-outwash sand and gravel to a depth of 520 ft. (158 m), is probably in hydrodynamic equilibrium with the present level of the sea and the height of the water table. However, two zones of freshwater between 730-820 ft. (222-250 m) and 900-930 ft. (274-283 m) are anomalously deep. A third zone extending from 1150-1500 ft. (350-457 m) contains slightly salty ground water (2 to 3 parts per thousand dissolved solids). Several explanations are possible, but the most likely is that large areas of the Continental Shelf were exposed to recharge by precipitation during long periods of low sea level in Pleistocene time. After the last retreat of glacial ice, seawater rapidly drowned the shelf around Nantucket Island. Since then, about 8000 years ago, the deep freshwater zones which underlie dense clay layers have not had time to adjust to a new equilibrium. Under similar circumstances freshwater may remain trapped under extensive areas of the Continental Shelf wherever clay confining beds have not permitted saltwater to intrude rapidly to new positions of hydrodynamic equilibrium. The implications are far reaching because all continental shelfs were exposed to similar hydrologic influences during Pleistocene time.
    Materialart: Digitale Medien
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  • 15
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of advanced nursing 10 (1985), S. 0 
    ISSN: 1365-2648
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: A questionnaire was given to nurses in two hospitals, one general and one psychiatric. Answers to the questions revealed a lack of knowledge of the natural history of hepatitis B infection. There were no apparent differences between specialities or grades of nursing staff. Confusion of hepatitis A infection with hepatitis B infection was not the cause of incorrect answers.
    Materialart: Digitale Medien
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  • 16
    facet.materialart.
    Unbekannt
    Berlin : Periodicals Archive Online (PAO)
    Klio. 8 (1908) 356-371 
    ISSN: 0075-6334
    Thema: Geschichte , Klassische Philologie, Byzantinistik, Mittellateinische und Neugriechische Philologie, Neulatein
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  • 17
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 5 (1991), S. 0 
    ISSN: 1365-2036
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Ten patients with an end jejunostomy and one with a jejuno-rectal anastomosis (jejunal length 30–140 cm) ate a constant chosen diet for 2 control days, and 2 test days when 40 mg omeprazole orally was taken each morning. In the 7 patients with a net secretory output of fluid, there was a mean reduction in wet weight of 0.66 kg/24 h (range –0.16 to 1.45 kg/24 h; P 〈 0.05) and sodium 46 mmol/24 h (– 51 to 135 mmol/24 h; N.S.); the four patients with net absorption of fluid showed no reduction in intestinal output. One patient with 30 cm jejunum responded little to oral but did so to intravenous 40 mg omeprazole twice a day with a reduction in wet weight of 3.00 kg/24 h and sodium 157 mmol/24 h. In one patient oral 40 mg omeprazole daily gave equivalent results to oral 300 mg ranitidine twice daily; in 2 others it was equivalent to intravenous 50 μg octreotide twice daily. Omeprazole reduces the intestinal output in patients with the short bowel syndrome and a net secretory output, but not enough to prevent the need for parenteral fluid and electrolyte replacement.
    Materialart: Digitale Medien
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  • 18
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 6 (1992), S. 0 
    ISSN: 1365-2036
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: To explore the role of alpha-1-adrenoreceptor-mediated pathways on human upper gut motor function in vivo, we studied the effects of the alpha-1-agonist phenylephrine and the alpha-1-antagonist thymoxamine on oro-caecal transit and antroduodenal motor activity. Transit was measured using a standard exhaled-breath hydrogen method, and motility was measured by intraluminal manometry.Oro-caecal transit was unaffected by 80 mg thymoxamine [median 63 min (range 35–164 min) vs. control, 65 min (range 30–155 min), P 〉 0.1]. However, phenylephrine (2.4 μg/kg/min) consistently delayed oro-caecal transit time to 103 min (50–215 min), P 〉 0.005. Co-administration of thymoxamine abolished this phenylephrine-induced delay.The mean amplitude of antral postprandial contractions was reduced by phenylephrine from 29 (13–37) to 10 (3–13) mmHg (P 〈 0.02). In contrast, neither the pattern nor the mean inter-contraction interval was altered. Responses to phenylephrine in the duodenum were similar to those in the antrum, with reduction in amplitude from 12 (3–18) to 6 (5–13) mmHg without alteration in the pattern or interval between contractions.Nutrient transit through the upper gut can thus be inhibited via activation of an alpha-1-adrenoreceptor-mediated pathway. Failure of alpha-1-antagonist administration to alter oro-caecal transit suggests that this pathway is not tonically active, and it is therefore unlikely to play a major role in nutrient passage under normal circumstances.
    Materialart: Digitale Medien
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  • 19
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 3 (1989), S. 0 
    ISSN: 1365-2036
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Six patients with short intestine (jejunal length 25–70 cm) on long-term parenteral nutrition, needing 4–5 L of intravenous fluid daily, were given octreotide (a somatostatin analogue, SMS 201–995) to investigate whether it would reduce beneficially their secretory diarrhoea (3.6–6.9 kg/day). They consumed the same diet for 2 control days, followed by 2 test days. Octreotide was given intravenously, initially in a dose of 50 μg b.d. through the central feeding line. There was a significant reduction of daily stomal output (0.5–5.0 kg) and daily sodium and potassium output; however there was no significant change in energy absorption. The response to octreotide was greatest in those patients who absorbed least nutrients. A dose increase to 100 μg t.d.s. gave no further measurable benefit though the patients found it smoothed-out the post-prandial rise in stomal output. Two patients were continued on long-term octreotide therapy, which allowed for a daily reduction in intravenous fluid of 1 and 1.5 L. Octreotide's anti-secretory effect was found to have been maintained when it was retested in one patient after a year of continuous therapy.
    Materialart: Digitale Medien
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  • 20
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 7 (1993), S. 0 
    ISSN: 1365-2036
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: To explore the effect of beta-adrenoreceptor stimulation and blockade on the extraction of monosaccharide from the upper gut, we first established the malabsorption threshold in 26 normal volunteers using a series of test meals containing varying proportions of fructose and glucose. Incomplete small intestinal extraction and consequent arrival of carbohydrate into the caecum was identified by a rise in exhaled breath hydrogen concentration. The malabsorption threshold varied between individuals from 30 to 80 g fructose (median 40 g) but was reproducible within individuals, with 90% agreement of repeat studies. The malabsorption threshold for an individual was unrelated to body height (r= 0.007, P 〉 0.05) or weight (r= 0.003, P 〉 0.05) but correlated closely with time to onset of the breath hydrogen rise of a standard meal (r= 0.70, P 〈 0.001). Administration of the beta-adrenoreceptor antagonist propranolol (160 mg) reduced the quantity of fructose required to exceed the malabsorption threshold from 45, 30–60 (median and range) to 40, 30–50 g (P= 0.03); administration of the beta-adrenoreceptor agonist isoprenaline (0.015, μg. kg/min) increased the quantity of fructose required to exceed the malabsorption threshold by 10 g (55 (50–90) g; P 〈 0.02). The effect of both drugs correlated closely with their transit effect (r= 0.79, P 〈 0.01). A beta-adrenoreceptor mediated pathway thus appears to be capable of influencing the extraction of monosaccharide from the small intestine in normal subjects both under resting and stimulated conditions, probably acting via an effect on upper gastrointestinal motility.
    Materialart: Digitale Medien
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