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  • 1
    Electronic Resource
    Electronic Resource
    Potent and highly selective neurokinin antagonists (1990)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 33 (1990), S. 1848-1851 
    Details
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jm00169a003
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of annealing on the defect structure in a-SiC:H films (1996)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 2216-2223 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The annealing behavior of amorphous, hydrogenated silicon carbide films in the range 400–900 °C was studied by optical characterization methods, 15N hydrogen profiling, and defect profiling using a variable energy positron beam. The films were deposited in an electron cyclotron resonance chemical vapor deposition system using ditertiary butyl silane [SiH2(C4H9)2] as the monosource for silicon and carbon. As-deposited films were found to contain large concentrations of hydrogen, both bonded and unbonded. Under rapid thermal annealing in a N2 atmosphere, the bonded hydrogen effuses giving rise to additional Si–C bond formation and to film densification. After annealing at high temperatures in N2, a marked decrease in the total hydrogen content is observed. After annealing in vacuum, however, the hydrogen effusion promotes void formation in the films. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.363049
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  • 3
    Electronic Resource
    Electronic Resource
    The thermal diffusivity tensor and lattice dynamics of β-oxygen at high pressure (1996)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 104 (1996), S. 5424-5428 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: An experimental approach to the study of thermal transport in the diamond-anvil high pressure cell is described and the elements of the thermal diffusivity tensor of β-oxygen are reported to a pressure of 9 GPa. The anisotropy in the thermal conductivity is found to be opposite in sense to that in the velocity of acoustic waves. Results are interpreted in terms of a lattice dynamical model in which the strong interactions between an atom and its first-, second-, and third-nearest neighbors are treated in tensorial form with parameters evaluated directly from experiment. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.471775
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  • 4
    Electronic Resource
    Electronic Resource
    Bound states of He atoms on Ag(110) (1996)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 105 (1996), S. 910-916 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The spectrum of bound states of He atoms adsorbed on Ag(110) is calculated, using an interaction potential based on effective medium theory EMT for the repulsive term A exp(−bz) and the Zaremba–Kohn form for the attractive van der Waals dispersion term. The electronic charge density of the host in the selvedge region is modeled by superimposing atomic-charge densities using the Herman–Skillman tables and the prefactor A of the repulsive term is fitted to the exact ground state energy obtained from elastic He scattering data. Comparisons are made with the bound-state spectrum extracted from the measured resonances in the He scattering data and with the results of several other models used in the current literature. An assessment of the role played by higher-order dispersion contributions to the attractive potential is also included. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.471934
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  • 5
    Electronic Resource
    Electronic Resource
    Collaborative development of a sun protection factor test method: a proposed European Standard. COLIPA Task Force ‘Sun Protection Measurement’, Europe (1996)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 18 (1996), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Standardization of the method to determine sun protection factors (SPF) is fundamental to uniform labelling of SPF values on sun products. The COLIPA Task Force ‘Sun Protection Measurement’(SPM), including representatives of major European sun-product manufacturers and contract testing laboratories, was established in 1990 to define methods for sun products testing. The process involved in developing the COLlPA SPF Test Method started with a critical appraisal of previously existing methods, and identification of areas for improvement. Experiments were performed by the participating laboratories to establish the new recommended test protocol which was then confirmed in two multicentred ring tests. Improvements to test methodology included the number and selection of volunteers and skin types, the application of the product, the definition of W output from solar simulators, and the method for assessing erythemal response (MED) including an option to use colorimetry to define objectively the ‘erythemal threshold’ of skin and to predetermine MED prior to exposure. Four cosmetic formulations and neutral density physical filters (SPF from 4 to 20) were tested in two ring tests. Results showed that variations in SPF of the cosmetic products were, on average, directly proportional to SPF value. An excellent correlation was found between visual and colorimetric SPF assessments (r = 0.99). An acceptable range of values for low and high SPF standard products was also established. The COLIPA SPF test method is now fully defined and supported by experimental data. Its use will harmonize SPF testing throughout Europe and help in the quest for global harmonization in testing sun products.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-2494.1996.tb00151.x
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  • 6
    Electronic Resource
    Electronic Resource
    AN UNEXPECTEDLY HIGH RATE OF ECTOPIC PREGNANCY FOLLOWING THE INDUCTION OF OVULATION WITH HUMAN PITUITARY AND CHORIONIC GONADOTROPHIN (1980)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 87 (1980), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Six tubal ectopic pregnancies occurred in a series of 193 pregnancies following ovulation induced with human pituitary gonadotrophin (hPG) and human chorionic gonadotrophin (hCG). The ectopic pregnancy rate of 3.1 per cent is higher than quoted incidences in the general population and occurred in the absence of predisposing factors. There was an association between ectopic pregnancy and elevated urinary oestrogen excretion in the peri-ovulatory phases of the induced ovulatory cycles. A urinary oestrogen excretion of greater than 200 μg/24 hours on day 0 (the day after hCG was given) was associated with a 10 per cent chance of ectopic pregnancy (P 〈0.05).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1980.tb04417.x
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  • 7
    Electronic Resource
    Electronic Resource
    AMNIOTIC FLUID PALMITIC ACID/STEARIC ACID RATIOS, LECITHIN/SPHINGOMYELIN RATIOS AND PALMITIC ACID CONCENTRATIONS IN THE ASSESSMENT OF FETAL LUNG MATURITY IN DIABETIC PREGNANCIES (1979)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 86 (1979), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The lecithin/sphingomyelin (L/S) ratio, palmitic acid concentration and palmitic to stearic acid (P/S) ratio were estimated on samples of amniotic fluid obtained from 66 patients with diabetes. These were compared with similar estimates on amniotic fluid obtained from 127 non-diabetic patients. At 35 to 40 weeks, significant differences were observed between the L/S ratio and palmitic acid concentration in diabetics and non-diabetics, whereas the P/S ratio was similar in the two groups. The amniotic fluid L/S ratio, palmitic acid concentration, and P/S ratio were estimated on amniotic fluid obtained from 20 diabetic patients within 48 hours of induction, and the clinical outcome of the newborn infant was used to assess the predictive value of the three parameters. In 19 out of the 20 diabetics the P/S ratio correctly predicted fetal lung maturity, whereas the palmitic acid concentration was correct in 12 patients and the L/S ratio in only 10 patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1979.tb11244.x
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  • 8
    Electronic Resource
    Electronic Resource
    URINARY OESTROGEN AND PREGNANEDIOL EXCRETION, ENDOMETRIAL AND OVARIAN PATHOLOGY AND BODY WEIGHT IN WOMEN WITH POSTMENOPAUSAL BLEEDING (1978)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 85 (1978), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Urinary oestrogen and pregnanediol excretion in 102 women who had a curettage for postmenopausal bleeding was correlated with the histological appearance of the endometrium, with age and with weight, and were compared with the values obtained in 42 normal postmenopausal women. The 36 patients with proliferative and hyperplastic endometrium and the 16 patients with endometrial carcinoma had significantly higher oestrogen excretion than the controls. The 27 patients with atrophic endometrium had only slightly higher mean oestrogen values than the controls. Twenty-three patients had taken hormones and the 20 patients who bled during treatment had the same urinary hormone values as the controls (excluding three patients with ovarian and/or endometrial carcinoma). The ovaries were examined in 37 patients who had a total hysterectomy and bilateral salpingo-oophorectomy. Significantly higher oestrogen values were found in those patients with ovarian tumours in which the stroma showed hyperplasia. When an ovarian tumour was associated with normal stroma or when the ovary showed cortical stromal hyperplasia without a tumour, urinary hormone values were normal. Oestrogen excretion and age were not related, but a correlation was found between oestrogen excretion and body weight.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1978.tb15843.x
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  • 9
    Electronic Resource
    Electronic Resource
    OESTROGEN EXCRETION AND OVARIAN PATHOLOGY IN POSTMENOPAUSAL WOMEN WITH ATYPICAL HYPERPLASIA, ADENOCARCINOMA AND MIXED ADENOSQUAMOUS CARCINOMA OF THE ENDOMETRIUM (1977)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 84 (1977), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Urinary oestrogen and pregnanediol excretion were measured before and after hysterectomy and bilateral salpingo-oophorectomy in 26 postmenopausal women with adenocarcinoma of the endometrium, 10 postmenopausal women with mixed adenosquamous carcinoma and 11 postmenopausal women with atypical hyperplasia (the patient groups). The results were compared with the values obtained in 22 active postmenopausal women, 20 hospitalized postmenopausal women and 18 women who had been subjected to hysterectomy and bilateral salpingo-oophorectomy for cancer of the cervix (the control groups). The ovaries and Fallopian tubes obtained at operation were examined for evidence of current or past excessive oestrogen production. Preoperative oestrogen values were higher in the patient groups than in the controls and the elevated values persisted after oophorectomy. The implications of these findings are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1977.tb12533.x
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  • 10
    Electronic Resource
    Electronic Resource
    CORPUS LUTEUM FUNCTION IN EARLY PREGNANCY FOLLOWING OVULATION INDUCTION WITH BROMOCRIPTINE (1977)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 84 (1977), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Serum prolactin levels and urinary oestrogen and pregnanediol excretion were measured during early pregnancy in 12 hyperprolactinaemic subjects who became pregnant during treatment with bromocriptine. Prolactin levels were suppressed below normal whilst taking the bromocriptine, but rose significantly when this drug was stopped and by eight weeks of gestation reached values significantly higher than those observed in normal pregnancy. Further increases in prolactin levels were, however, not observed. Urinary oestrogen and pregnanediol excretion was initially normal but, following cessation of bromocriptine, urinary pregnanediol excretion decreased and was significantly less than normal at 11 to 14 weeks gestation. These results suggest that elevated prolactin levels affect corpus luteum function of early pregnancy. Because the effect is maintained until at least 14 weeks gestation, prolactin may also affect progesterone production by the placenta.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1977.tb12518.x
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