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  • 27.60+j  (1)
  • Soluble CD 14  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Production and identification of100Sn (1994)
    Springer
    The European physical journal 348 (1994), S. 241-242 
    Details
    ISSN: 1434-601X
    Schlagwort(e): 27.60+j ; 29.30-h
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract We report the first observation of the doubly-magic nucleus100Sn. This isotope was produced by nuclear fragmentation of124Xe projectiles at 1095 A·MeV using the heavy-ion synchrotron SIS at GSI, Darmstadt. The projectile fragments were separated in flight with the projectile-fragment separator FRS and identified by measuring event by event the magnetic rigidity, the time of flight and the energy deposition.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01305875
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Evaluation of soluble CD14 and neopterin as serum parameters of the inflammatory activity of pulmonary sarcoidosis (1992)
    Springer
    Journal of molecular medicine 70 (1992), S. 909-916 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Sarcoidosis ; Immune response ; Activity markers ; Soluble CD 14 ; Serum neopterin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary CD14 represents the most specific marker for monocytes/macrophages. It has been demonstrated in vitro that monocytes/macrophages lose this antigen upon activation. Results of studies investigating the expression of membrane-bound CD14 on the surface of monocytes/macrophages in sarcoidosis patients are controversial. To investigate whether the soluble form of CD14 reflects monocyte/macrophage activation in sarcoidosis, serum levels of soluble CD14 were determined concurrently with other serum markers of monocyte/macrophage activation (neopterin, angiotensin-converting enzyme) in 50 consecutive patients with bioptically confirmed sarcoidosis. The patients were allocated to three groups according to disease activity and therapy. The soluble interleukin-2 receptor in serum and the CD4/CD8 ratio in lavage fluid were used to monitor T-lymphocyte activation. No significant differences in serum or bronchoalveolar lavage levels of soluble CD14 were observed in patients with active or inactive sarcoidosis. Despite the presence of normal soluble CD14 serum concentrations a correlation with serum neopterin and angiotensin-converting enzyme was found in active sarcoidosis (soluble CD14 versus neopterin, r s = 0.61 and 0.65, P〈 0.05 and 0.01, respectively; soluble CD14 versus angiotensin-converting enzyme, rs=0.6 and 0.72, P〈 0.02 and 0.003, respectively). A correlation between soluble CD14 and parameters of T-cell activity was not demonstrated. We therefore conclude that soluble CD14 in serum is not a useful clinical parameter in establishing disease activity in sarcoidosis. Neopterin and angiotensin-converting enzyme serum concentrations are parameters with higher sensitivity, although specificity remains very low. The exact role of CD14 antigen in sarcoidosis requires further investigation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00180437
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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