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  • 1
    Digitale Medien
    Digitale Medien
    Mechanical properties of LaNi5 thin films prepared by sputtering and vapor deposition methods and determination of the hydrogen content in these films (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 888-892 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Amorphous LaNi5 films were prepared using a sputtering method. Mechanical properties and hydrogenation characteristics of the films were investigated and the results were compared with those of the deposited films. The density of the sputtered LaNi5 film was about 6 g/cm3, which was larger than that of the evaporation deposited film but smaller than that of crystalline LaNi5. Thermal conductivities of amorphous films were larger than those of bulk samples. Mechanical strength of the sputtered films deposited on various substrates was measured after 100 cycles of hyrogen absorption–desorption process. The result was in the following order for the substrates used: Ni foil〉Ni〉Al foil〉Cu foil〉Cu〉Al〉glass. The hydrogen content in a sputtered film with a thickness of 1.3 μm was found to be 2.4 H/LaNi5. The hydrogen concentration in the film increased monotonically with increasing the hydrogen pressure in both cases between 333 and 363 K.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.341943
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  • 2
    Digitale Medien
    Digitale Medien
    Superoxide dismutase in psoriasis, squamous cell carcinoma and basal cell epithelioma: an immunohistochemical study (1991)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 124 (1991), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Monoclonal antibodies against human Cu, Zn-superoxide dismutase (SOD) and Mn-SOD were used to stain frozen sections of normal and abnormal human skin. In normal human epidermis, the Cu, Zn-SOD antibody almost exclusively stained the basal cells. Mn-SOD antibody weakly stained the whole of the epidermis but more predominantly the basal cell layer. In psoriasis, Cu, Zn-SOD antibody mainly stained the basal cells of the lowest parts of the elongated rete ridges. Basal cells corresponding to the tip of the dermal papillae were weakly stained. Mn-SOD staining was considerably decreased in the psoriatic epidermis. In squamous cell carcinoma, staining with both Cu, Zn-SOD and Mn-SOD antibodies was decreased, and single cells positive for Cu, Zn-SOD were scattered throughout the tumour nests. In basal cell epithelioma, Cu, Zn-SOD staining was intense and diffusely distributed throughout the tumour nests, while Mn-SOD staining was absent.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1991.tb04950.x
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  • 3
    Digitale Medien
    Digitale Medien
    Induction of Suppressor Activity on B-Cell Differentiation in Human T-Cell Subset without Fc(IgG) Receptors by Levamisole Administration (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 10 (1979), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: A single oral dose of 150 mg levamisole was administered to five healthy adults. Circulating Fc(IgG) receptor-bearing T cells (Tγ cells) increased for 5 days after levamisole intake, but total E rosette-forming cells showed no significant alterations. The generation of immunoglobulin-producing cells in the peripheral blood lymphocytes (PBL), which was induced in the in vitro pokeweed mitogen (PWM)-stimulated cultures, was significantly suppressed for 5 days after levamisole administration. Suppressor T-cell activity on B-cell differentiation, which was induced by levamisole intake, was evaluated by co-culturing with allogeneic untreated adult PBL in the PWM system in six other volunteers. A seemingly dose-dependent suppression on B-cell differentiation was exerted by T cells isolated on day 3 of levamisole treatment, but not by T cells which were isolated before or on day 14 of the experiment. When T cells were fractionated into two subsets with regard to the presence or absence of Fc(IgG) receptors, suppressor T-cell activity appeared to be generated by levamisole largely in T cells lacking Fc(IgG) receptors, but not in Tγ cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1979.tb01387.x
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  • 4
    Digitale Medien
    Digitale Medien
    Induction of E-Rosette-Promoting Factor in Human Plasma by Levamisole: An Assessment in a Patient with Partial DiGeorge Syndrome (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 15 (1982), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: A male infant with partial DiGeorge syndrome responded to weekly administration of levamisole (2.5 mg/kg of body weight) with an increase of circulating E-rosette-forming T cells. Thymic hormone activity in plasma appeared to be elevated to a near-normal level of 11.6 ng thymopoietin equivalent/ml after levamisole administration. The in vitro incubation studies indicated that levamisole by itself had no E-rosette-promoting ability, but a dialysable and relatively heat-stable plasma factor induced by levamisole both in the patient and in heallhy individuals had E-rosette-promoting activity for the patient's lymphocytes. Such a plasma factor, however, could not be induced in all four thymectomized myasthenic subjects examined, suggesting a thymus-dependent nature of the plasma factor. These results suggest that levamisole might mediate an increased secretion of humoral factor(s) with E-rosette-promoting activity, even from such a rudimentary thymus as in the partial DiGeorge syndrome.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1982.tb00632.x
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  • 5
    Digitale Medien
    Digitale Medien
    T-Cell-Dependent Production of IgG by Human Cord Blood B Cells in Reconstituted SCID Mice (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 35 (1992), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Reconstitution of severe combined immunodeficient (SCID) mice with human lymphocytes has recently allowed the elucidation of abnormalities of immune responses in various immunological disorders. In the present study, mononuclear cells (MNC) from neonatal cord blood and adult peripheral blood were intraperitoneally injected into SCID mice to examine induction of human Ig in respective mice recipients. Human IgG was consistently detected in the serum of SCID transferred with adult MNC, but only a few SCID recipients of cord blood MNC showed detectable but low levels of IgG in the serum. The combination experiments of isolated B and T cells disclosed that some interactions between B and T cells might be necessary for IgG production in transferred SCID mice. Notably, transfer of cord blood B cells with adult but not cord blood T cells resulted in efficient induction of IgG, associated with a change in subclass distribution. The results suggest that inability of neonatal B cells to produce IgG can be overcome by transfer with adult mature T cells into SCID mice.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1992.tb02876.x
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  • 6
    Digitale Medien
    Digitale Medien
    Heterosis for neonatal survival in the guppy (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 60 (2002), S. 0 
    Details
    ISSN: 1095-8649
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: Neonatal survival rate ranged from 91.8 to 100.0% in 12 populations of the guppy Poecilia reticulata, and was higher in naturalized Japanese stream populations than in domestic strains. Mean heterozygosity at five allozyme and four microsatellite loci varied between 0.112 and 0.430 and was significantly correlated with neonatal survival rate among populations, suggest ing that inbreeding decreases neonatal survival. Diallel and reciprocal crosses among four domestic strains demonstrated heterosis for neonatal survival. These results indicate that neonatal survival is genetically affected by heterosis and its antithesis, inbreeding depression. The relationship between neonatal survival and the mean heterozygosity suggests that overall heterozygosity is important for neonatal survival of the guppy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1095-8649.2002.tb01695.x
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  • 7
    Digitale Medien
    Digitale Medien
    Determination of the hydrogen content in amorphous lanthanum-nickel (LaNi5) films using a quartz-crystal mass-monitoring method (1985)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 89 (1985), S. 5550-5552 
    Details
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/j100271a048
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  • 8
    Digitale Medien
    Digitale Medien
    Transient Increase of IgG Fc Receptor-Bearing T Lymphocytes following Positive PPD Skin Testing (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 8 (1978), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: In tuberculin-sensitive individuals, IgG Fc receptor (FcR)-hearing lymphocytes in the peripheral blood increased transiently following PPD-tuberculin skin test. This rise in circulating FcR-bearing cells appeared to peak about 36–48 h after the intradermal inoculation of PPD and seemed to occur largely in the T cell population. Skin test-negative individuals showed no significant changes in their circulating FcR-bearing cells following PPD inoculation. Peripheral blood lymphocytes from PPD-sensitive individuals were fractionated into non-T cell and T cell-enriched populations by E rosette sedimentation technique. FcR-bearing cells in the T cell-enriched population were eliminated by EA rosette sedimentation: i. e. FcR-negative T cells. Then, equal numbers (1 × 105 cells each) of non-T cells and unfractionated or FcR-negative T cells were recombined in culture. Prior to PPD inoculation, there was no significant difference between these two cell mixtures in the in vitro cellular response to PPD or mitogens. When these cell populations were obtained. 16–48 h after PPD inoculation, however, the combination of non-T tells and FcR-negative T cells responded to PPD much better than the combination of non-T cells and unfractionated T cells, whereas the mitogen-induced cellular proliferation of these two cell mixtures did not differ from each other.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1978.tb00510.x
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  • 9
    Digitale Medien
    Digitale Medien
    EFFECTS OF ENDURANCE TRAINING ON SUPEROXIDE DISMUTASE ACTIVITY, CONTENT AND mRNA EXPRESSION IN RAT MUSCLE (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 24 (1997), S. 0 
    Details
    ISSN: 1440-1681
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: 1. The purpose of the present study was to investigate the changes in superoxide dismutase (SOD) isoenzyme (Mn2+-SOD and Cu2+, Zn2+-SOD) activities, contents and mRNA expressions in rat skeletal muscle during endurance training and a single bout of exercise.2. Thirty-eight male Wistar rats were divided into untrained (U) and trained (T) groups. The T group rats were treadmill-trained for 9 weeks. The activity, content and mRNA expression of Mn2+-SOD and Cu2+, Zn2+-SOD were determined in the soleus muscle of each rat.3. Mn2+-SOD activity and content in the T group were significantly higher than in the U group, both at rest (22 and 21%, respectively) and after exercise (24 and 46%, respectively), while a single bout of exercise affected neither the activity nor content of Mn2+-SOD in either group.4. The content of Cu2+, Zn2+-SOD in both groups was not different at rest and after exercise, although its activity at rest was significantly higher in the T group than in the U group (by 29%).5. After exercise, the expression of Mn2+-SOD mRNA was markedly attenuated only in the U group (49%); the expression of Cu2+, Zn2+-SOD mRNA was not influenced by exercise.6. Our results suggest that adequate endurance training increases both the activity and content of Mn2+-SOD and that untrained rats are rather susceptible to oxidative stress during physical exercise. It thus appears that Mn2+-SOD provides a reliable index of physical training.7. The results obtained in the present study also suggest that muscle has the capacity of responding to training in such a manner as to reduce the potential harm arising from the accumulation of oxygen free radicals resulting from enhanced metabolic activity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-1681.1997.tb01196.x
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  • 10
    Digitale Medien
    Digitale Medien
    Genetic differences in some haematological traits of communally reared clonal ayu, Plecoglossus altivelis Temminck & Schlegel, under stressed and non-stressed conditions (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Aquaculture research 27 (1996), S. 0 
    Details
    ISSN: 1365-2109
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Four clonal lines of ayu, Plecoglossus altivelis Temminck & Schlegel, were produced through gynogenesis, mixed before hatching and reared communally. After 10 months, a randomly taken sample was subjected to a standardized shallow-water stressor. Haematocrit, haemoglobin, red blood cells count (RBC) and mean corpuscular volume (MCV) were obtained from stressed and non-stressed fish. DNA fingerprinting was used to confirm the clonal nature of the organisms and to identify the clonal line to which each fish belonged.We observed significant differences between clonal lines mostly in the haematocrit and MCV measured under no-stress conditions. Such differences are suggested to represent mainly genetic variance, on account of the common environment provided to all the experimental groups.The stress response ratio was lower than expected, mainly due to some unexpectedly high non-stress values.Heritability values (h2) were medium to high for the no-stress measurements (mean 0.238) and very low or zero for the stressed groups’traits (excepting one high value of 0.484).We conclude that the use of communally reared clonal lines represents a good tool for the characterization of the physiological traits, thus allowing for their utilization as genetic selection criteria.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1365-2109.1996.00804.x
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