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  • 1980-1984  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 40 (1984), S. 70-73 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The intensity of sound-induced convulsions in the genetically epilepsy-prone rat (GEPR) was reduced in a dose related fashion by intracerebroventricular administration of dobutamine, (β1 agonist), terbutaline (β2 agonist) or phenylephrine (α1 agonist). BHT-920 (α2 agonist) did not cause a dose-related decrease in sound-induced convulsion intensity. Binding studies showed that whole brain α and β receptor densities (Bmax) were normal while the Kd was increased for the β ligand in GEPR brain.
    Type of Medium: Electronic Resource
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