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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Anaesthesist 44 (1995), S. 24-36 
    ISSN: 1432-055X
    Keywords: Schlüsselwörter: Thorakale Epiduralanästhesie – Epidurographie – CT-Epidurographie – Epiduralraum – Schienenstrangphänomen – Plica mediana dorsalis ; Key words: Epidural anaesthesia – Epidural space – Epidurography – CT epidurography – Rail-road-track phenomenon – Plica mediana dorsalis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract. Epidurography with contrast medium is used to verify the correct poition of an epidural catheter and to detect malpositioning. There is great variability in the distribution of contrast medium according to the individual morphology of the epidural space and the way it is injected. Results of investigations of the anatomy of the spinal canal and epidural space performed with anatomic specimens, epiduroscopy, and conventional and computed tomographic (CT) epidurography are sometimes contradictory. We have performed CT epidurography in approximately 30 patients to date. Insights regarding the distribution of contrast medium in the epidural space can help to interpret conventional epidurographies and to explain special features, such as the "rail-road-track phenomenon" or the plica mediana dorsalis. Methods. Patients scheduled for major abdominal operations were studied. Catheters were introduced into the thoracic epidural space on the day before the operation. Conventional epidurographies were performed routinely after insertion of the catheters with a mobile X-ray apparatus, usually in the recovery room, using 5 ml iopamidol (Solutrast 250 M). Selected patients (good mental state and stable psychic condition), after written consent and with approval of the local ethical committee, were investigated with CT epidurography using the same contrast medium (partly diluted). From among the CT scans performed until now, five characteristic images are presented and compared to conventional epidurographies. Results. When small volumes (5 mL) of iopamidol were injected slowly, we regularly observed a railroad-track phenomenon in the AP images of conventional epidurographies. After rapid injection of larger volumes (10 – 15 ml), the spread was more homogeneous and sometimes outline a lighter zone of contrast distribution in the midline. CT epidurography in these cases (5 out of 30 patients) revealed a plica mediana dorsalis. In the majority of the CT scans of the thoracic epidural space its anterior (ventral) compartment was unfilled by contrast medium. According to the findings of several investigators, dura mater and ligamentum longitudinale posterius have grown together, so that an epidural space does not exist in ventral thoracic segments of the spinal canal. In lower thoracic and lumbar segments both structures are separate, and a wide anterior epidural space was present and filled with contrast medium. In other cases the dorsal and dorsolateral epidural space was completely filled, but the contrast medium stopped behind the spinal nerves and surrounding dural sheaths, as if these structures, together with the connective tissue strands between them, formed a membrane that spread in a frontal plane. A railroad-track phenomenon is interpreted in the literature as the X-ray correlate of contrast medium spread in the subdural space, indicating an incorrect catheter position. According to conventional epidurographies and confirmed by CT scans, this feature is also seen regulary in cases with correct catheter position. Small volumes of iopamidol spread preferentially into the wider parts of the epidural space between the gaps of the vertebral arcs, whereas the dura mater and periosteal layers touch at the inner side of the pedicules and laminae, allowing the existence of only a potential epidural space. This rhythmic widening and narrowing of the epidural space is the explanation of the "railroad track" in AP contrast epidurographies. Conclusions. CT epidurography is a valuable tool to provide better insight into the morphology of the epidural space when filled with fluid (contrast medium, local anaesthetics), complementing findings using epiduroscopy and anatomic specimens. It stands to reason that this time- and cost-expensive method can never replace conventional epidurographies, but can help to interpret them properly.
    Notes: Zusammenfassung. CT-Epidurographien nach Kontrastmittelinjektion wurden bei ca. 30 Patienten nach Anlage eines thorakalen Epiduralkatheters angefertigt. Diese wurden mit konventionellen Röntgenaufnahmen verglichen. Entsprechend der individuellen Morphologie des Epiduralraums gibt es unterschiedliche Kontrastmittelmuster bei der CT-Epidurographie, wobei typische Bilder immer wiederkehren. Schienenstrangphänomen: Dieses Bild bei konventionellen a.p.-Aufnahmen, in der Literatur meist als subdurale Katheterlage interpretiert, ist Ausdruck einer segmental rhythmisch wechselnden Kontrastmittelfüllung des lateralen Epiduralraums. Anteriorer Epiduralraum: Im thorakalen Teil des Wirbelkanals sind Dura mater und Ligamentum longitudinale posterius miteinander verwachsen, so daß hier kein ventraler Epiduralraum existiert, was auf konventionellen Röntgenbildern im lateralen Strahlengang durch fehlende Kontrastierung der vorderen Lamelle zu erkennen ist und in den CT-Scans verifiziert wird. Plica mediana dorsalis: Bei stärkerer Kontrastierung des Epiduralraums zeigt sich in manchen Fällen eine mediane Aufhellungszone in konventionellen a.p.-Epidurographien, die sich im CT-Scan als Plica mediana dorsalis herausstellt. Spinalnerven: In manchen CT-Scans sind dorsaler und dorsolateraler Epiduralraum prall mit Kontrastmittel gefüllt. Dieses stoppt aber hinter den Spinalnerven, so daß man annehmen muß, hier existiert eine in Frontalebene ausgespannte Membran, welche durch die Spinalnerven, das Spinalganglion, die umgebende Durascheide und durch Fortsetzungen des Ligamentum denticulatum gebildet wird. Die CT-Epidurographie ist eine wertvolle Methode, um neue Einsichten über die Morphologie des Epiduralraums zu erhalten. Sie kann die konventionelle Epidurographie nicht ersetzen (Strahlenbelastung, Aufwand, Kosten), aber die mit dieser Methode gewonnenen Ergebnisse tragen dazu bei, konventionelle Epidurographien richtig zu interpretieren.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Key words: Papilloma ; Breast ; MRM ; Galactography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of this study was evaluation of MRI alone and in combination with mammography and galactography in the diagnosis of intraductal papillomas. From 1994 to 1998, a total of 48 women presenting with pathologic mammary secretion underwent galactography and magnetic resonance mammography (MRM). Thirty-five patients aged 16–71 years (average age 46 years) subsequently underwent surgery or diagnostic puncture and the histologic findings were compared with the results of the radiologic examination. Histology revealed papillomas in 16 cases. In 6 of these patients, there was associated malignant degeneration. Malignancy without associated papilloma was observed in 3 cases. Galactography displayed a sensitivity of 94 % and a specificity of 79 % with five false-positive findings and one false-negative finding in the recognition of intraductal papillomas. Malignant processes were detected by mammography/galactography in only one instance. Magnetic resonance mammography visualized pathologic contrast medium uptake in 8 of 9 cases of malignant disease (sensitivity 89 %). One patient with in situ ductal carcinoma escaped detection with MRM. Papillomas showed no or below-the-threshold-lying contrast uptakes with no specific sign suggestive of papilloma. Galactography in combination with mammography remains the primary diagnostic procedure in cases of pathologic mammary secretion or suspected papilloma. The addition of MRI permits exclusion of malignant disease with a high degree of certainty; thus, expectant management in individual cases with negative findings appears justified.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 39 (1999), S. 790-794 
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Intraarterielle Chemotherapie ; Mammakarzinom ; Mitoxantron ; Thromboembolie ; Key words Intraarterial chemotherapy ; Breast cancer ; Mitoxantrone ; Thromboembolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A general review of the results and technique of intraarterial chemotherapy in cases of breast cancer is given. The remission rate for untreated primary tumors is nearly 100%, for completely treated local relapses approximately 70%. The complication rate is quite low using an intraarterial well-tolerated cytostatic agent such as mitoxantrone. However, thromboembolism of the vertebral artery facing the internal mammary artery may occur. The indication for intraarterial chemotherapy should always be set by an interdisciplinary board.
    Notes: Zusammenfassung In der vorliegenden Arbeit werden Technik und Ergebnisse der intraarteriellen Chemotherapie beim Mammakarzinom übersichtsartig beschrieben. Die Remissionsraten für einen unbehandelten Primärtumor liegen bei nahezu 100%, beim ausbehandelten Lokalrezidiv bei ca. 70%. Unter Verwendung eines intraarteriell gut verträglichen Zytostatikums wie Mitoxantron sind die Komplikationsraten gering, zu fürchten ist vor allem eine Thromboembolie in die gegenüber der A. mammaria interna gelegene A. vertebralis. Die Indikation zur intraarteriellen Chemotherapie sollte immer interdisziplinär gestellt werden.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 36 (1996), S. 591-592 
    ISSN: 1432-2102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 36 (1996), S. 843-844 
    ISSN: 1432-2102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-2102
    Keywords: Schlüsselwörter A. ischiadica ; Aneurysma ; Thrombolyse ; Angiographie ; Keywords Sciatic artery ; Aneurysm ; Thrombolysis ; Angiography ; Stentgraft
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The sciatic artery is a rarely seen variant of the vessels of the lower limb. Anatomically it is the prolongation of the inferior gluteal artery and accompanies the sciatic nerve from the sciatic foramen to the knee. More than other vessels, the sciatic artery shows vasculopathies like diffuse dilatation or aneurysms. This report describes an interesting case of embolic acute ischemia, caused by a persistent sciatic artery with an aneurysm. We treated the ischemia with intraA. l lysis and bridged the aneurysm with an covered stent.
    Notes: Zusammenfassung Die A. ischiadica ist eine selten zu findende anatomische Variante des Gefäßsystems der unteren Extremität. Anatomisch entspricht die A. ischiadica einer Verlängerung der A. glutea inferior und begleitet den N. ischiadicus ab dem Foramen ischiadicum bis zum Knie, wo sie in die Unterschenkelarterien mündet und zu den muskelversorgenden Arterien gehört. Die A. ischiadica neigt aufgrund eines minderwertigen Gefäßaufbaus zu Vaskulopathien. Insbesondere aneurysmale Dilatationen der A. ischiadica sind mit einer hohen Inzidenz beschrieben worden. Der vorliegende Fallbericht beschreibt den interessanten Fall einer akuten Ischämie im Bereich des Unterschenkels, ausgelöst durch Thromben aus einer aneurysmatisch veränderten A. ischiadica. Die akute Ischämie wurde erfolgreich durch eine intraarterielle Lyse behandelt. Das Aneurysma wurde sekundär durch eine beschichtete Stentprothese ausgeschaltet.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1084
    Keywords: Key words: MR imaging – Gastrointestinal tract – Contrast agent – Inflammatory bowel disease – Crohn's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of the study was to evaluate the additional findings of MRI following small bowel enteroclysis and to compare the efficacy of negative and positive intraluminal contrast agents. Fifty patients with inflammatory or tumorous small bowel disease were investigated by small bowel enteroclysis and consecutive MRI using breathhold protocol (T1-weighted fast low-angle shot, T2-weighted turbo spin echo). Patients were randomly assigned to either receiving a positive oral (Magnevist, Schering, Berlin, Germany) or a negative oral MR contrast media (Abdoscan, Nycomed, Oslo, Norway). The pattern of contrast distribution, the contrast effect, presence of artifacts, as well as bowel wall and extraluminal changes, were determined and compared between the contrast type using Fischer's exact test. Sensitivity, specificity, and diagnostic accuracy for MRI and enteroclysis were calculated. Twenty-seven patients had clinically proven Crohn's disease and two patients surgically proven small bowel tumours. Magnetic resonance imaging had important additional findings as abscesses and fistulae in 20 patients. Surgically compared sensitivities were 100 and 0 % for MRI and enteroclysis, for the detection of abscesses, and 83.3 and 17 % for the diagnosis of fistulae, respectively. Bowel wall thickening was more reliably detected with use of positive oral contrast media without intravenous enhancement (p 〈 0.001), whereas postcontrast negative oral contrast media allow for a superior detection (p 〈 0.001). T2-weighted sequences were necessary with use of negative oral contrast media, because loop abscesses may be masked. Magnetic resonance imaging should be performed in all patients with suspicion of extraintestinal complications, because the complications are more reliably detected by MRI. Negative oral contrast media show advantages with the use of intravenous contrast but can mask loop abscesses using only T1-weighted imaging.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 7 (1997), S. 589-590 
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 8 (1998), S. 1452-1454 
    ISSN: 1432-1084
    Keywords: Key words: Epidurography ; MRI ; CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of this study was to evaluate and describe MRI epidurography as a new imaging tool. Five volunteers and one patient were investigated with MR epidurography after injection of 20 ml Gd-DPTA solution (1 : 250/1 ml Gd-DPTA/250 ml normal saline). Magnetic resonance epidurography is possible. With fat-suppression techniques, the contrast between Gd-DPTA solution in the epidural space and surrounding soft tissue proved adequate. Using the multiplanar capability of MRI with MR epidurography coronal and sagittal projections similar to conventional epidurography, axial slices comparable to CT epidurography can be obtained. Magnetic resonance epidurography is superior to conventional and CT epidurography. Presently, due to high costs as compared with conventional and CT epidurography, MRI is not suitable for the routine monitoring of peridural catheters, but it may have a place in the future with decreasing costs for MRI and for the evaluation of patients with spine pathology, especially in describing epidural processes.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1084
    Keywords: Key words: Breast ; Parenchymal pattern ; MR imaging ; Contrast enhancement ; MR mammography ; Menstruation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Magnetic resonance mammography (MRM) provides data regarding the nature of tumours based on contrast medium dynamics; fibrocystic changes in the breast, however, may lead to false-positive results. This study investigated whether the contrast medium dynamics of fibrocystic changes are dependent on the menstrual cycle. Twenty-four patients with palpable lumps but normal mammographies and ultrasound studies were examined. The MRM technique was performed during the first and second part of the menstrual cycle using a FLASH 3D sequence, both native and at 1, 2, 3 and 8 min after intravenous application of 0.15 mmol/kg body weight of gadodiamide. The calculated time–intensity curves were evaluated based on the following criteria: early percentage of contrast medium uptake in relation to the native value; formation of a plateau phenomenon after the second minute; the point of maximal contrast medium uptake; and calculation of the contrast enhancing index. During the second half of the menstrual cycle, a generally greater contrast medium uptake was observed. Nevertheless, when further diagnostic criteria, such as continuous contrast medium increase as a function of time, were considered, there was no increased rate of false-positive findings. The phase of the menstrual cycle may affect the specificity of the examination, if only the quantitative contrast medium uptake and the percentage of contrast medium uptake in the first 2 min are considered. A control MRM during the other half of the cycle may then be indicated and additional diagnostic criteria may improve specificity.
    Type of Medium: Electronic Resource
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