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  • 1
    Electronic Resource
    Electronic Resource
    Stimulation of human fetal astrocyte proliferation by bacterial lipopolysaccharides and lipid A (1991)
    Springer
    Acta neuropathologica 82 (1991), S. 384-388 
    Details
    ISSN: 1432-0533
    Keywords: Bacterial endotoxin ; Lipopolysaccharide ; Lipid A ; Culture astrocyte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This report concerns the effect of bacterial endotoxin [lipopolysaccharide(LPS) and lipid A] on cultured human fetal astrocytes. Exposure to 1 μg/ml LPS or lipd A caused a striking stimulation of the rate of proliferation of the cells. The effect was most pronounced with exponentially growing cultures. Stimulation was associated with enhance DNA synthesis as ascertained by [3H]thymidine incorporation. These findings at the cellular level may be of relevance in the elucidation of the effects of bacterial endotoxins on the developing human brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296549
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