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  • 1
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 15 (2001), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Data on the proton pump inhibitor lansoprazole in paediatric patients are limited.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To investigate the pharmacokinetics, optimal dosage and efficacy of lansoprazole in paediatric patients.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:A 24-h gastric pH recording and a pharmacokinetic study were performed after 7 days of lansoprazole, 17 mg/m2, in 23 patients with reflux oesophagitis (median age, 3.5 years). Response was defined as pH 〉 3 for 〉 65% of the recording. The dosage was doubled in non-responders. Patients with no response on day 14 were excluded. Responders underwent endoscopy after 4 weeks on the response-inducing dosage; abnormal findings led to a repeat endoscopy after four additional weeks.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Nine patients responded to 17 mg/m2 and six to 30.3 mg/m2. On day 7, time with pH 〉 3 was significantly correlated with the area under the plasma concentration–time curve (P=0.003). The area under the plasma concentration–time curve was significantly greater in the nine responders to 17 mg/m2 than in the 14 other patients. Pharmacokinetic parameters were similar in responders and non-responders to the higher dose. After 4 weeks, oesophagitis was healed in 80% of responders. Adverse events occurred in three patients and required treatment discontinuation in one.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Lansoprazole is effective and safe in children. The optimal starting dosage is 30 mg/m2 or 1.4 mg/kg.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Optics Communications 17 (1976), S. 103-105 
    ISSN: 0030-4018
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physics Letters A 34 (1971), S. 313-314 
    ISSN: 0375-9601
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Aquaculture 120 (1994), S. 341-346 
    ISSN: 0044-8486
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Solid State Ionics 26 (1988), S. 152 
    ISSN: 0167-2738
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 9 (1987), S. 179-184 
    ISSN: 1279-8517
    Keywords: Transfixion ; External fixation ; Thigh
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé A l'aide de coupes anatomiques étagées, de niveeaux précis, les possibilités de transfixion du squelette, sans léser les axes vasculo-nerveux, les tendons principaux et sans pénétration articulaire sont étudiées. Après détermination de secteurs de transfixion sans danger sont précisés le lieu sur la peau de la cuisse où la Pénétration et la sortie des broches doit se faire. Deux bandes représentant le quart de la circonférence locale sont individualisées servant d'accès: l'une débute ventralement sur la hanche pour se terminer à la face médiale du genou, l'autre débute à la face dorsale de la fesse pour se terminer à la face latérale du genou.
    Notes: Summary Serial cross-sections of the thigh have been used to indicate where osseous transfixion is possible without damaging neuro-vascular structures or major tendons or penetrating a joint. Safe areas for transfixion using fine wires and their corresponding cutaneous zones are indicated. Two cutaneous zones each representing a quarter of the circumference of the thigh form Safe Zones for transfixion. The first begins on the ventral surface of the hip and ends on the medial aspect of the knee, while the second begins on the posterior aspect of the buttock and ends on the lateral aspect of the knee.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 11 (1989), S. 13-15 
    ISSN: 1279-8517
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion Dans le cadre des interventions de réinnervation laryngée sélective, il est indispensable de disséquer la branche antérieure intralaryngée du n. laryngé inférieur jusqu'à l'origine du n. aryténoïdien sans oublier les premiers millimètres de ce nerf. On isolera ainsi tous les pédicules destinés au m. crico-aryténoïdien dorsal, c'est-àdire tous les pédicules abducteurs. Nous nous proposons dans un premier temps de réséquer la petite corne du cartilage thyroïde qui permettra dans 60% des cas une bonne vision de tous les pédicules abducteurs. Dans les 40% restants on complétera cette résection par la taille d'un volet cartilagineux thyroïdien postéro-inférieur. Dans les innervations du m. cricoaryténoïdien dorsal de type I, le seul pédicule est abducteur et la portion de la branche antérieure située au-dessus est considérée comme adductrice. Dans les innervations de type II et III on n'utilisera qu'un seul pédicule abducteur pour les anastomoses, les autres devant être sectionnées. La branche antérieure située au-dessus du pédicule choisi est la branche adductrice.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1998
    Keywords: Cortical hyperostosis ; Mandible
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Four patients who presented with predominant or exclusive face and orbital involvement by de Toni-Caffey's disease are reported. Facial manifestations of infantile cortical hyperostosis may be the first and sometimes the only manifestation of the disease. A mandibular involvement is almost always present and its characteristic appearance leads to the diagnosis of de Toni-Caffey's disease.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1998
    Keywords: Bone dysplasia ; Growth disorders ; Hyperostosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three pediatric cases of melorheostosis are described. Growth disorders of the limbs are often the first signs in children. The radiological appearance consists of long tracks of increased cortical radiodensity in the long bones and of small dense islets in the epiphyses.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 14 (1984), S. 407-412 
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The question of radiological mass screening for congenital dislocated hip is still debated. We have tried to evaluate the cost-benefit ratio of radiological detection at the age of 3–4 months, taking into account the socio-economic cost and radiation risk. Assuming a frequency of this disorder of 1% the average cost of treatment of one case detected by X-ray screening at the age of 3–4 months, including the price of X-ray examinations of 99 normal babies, is 23,374 FF. The average cost of treatment of a case detected when walking (i.e. after 9 months) is 84,230 FF. The cost-benefit ratio is 3.6. In countries where the frequency reaches 2% the cost benefit ratio is 4.57. It also appears from our study that the irradiation of the patient is much smaller when the diagnosis is made earlier. Comparing the slight irradiation delivered to normal infants by this mass screening to the heavy irradiation received by a few individuals whose treatment is started after 9 months, the calculated risk of leukemia or of genetic disorder for the whole population still favours a systematic X-ray film of the pelvis at age 3–4 months. However, if it were decided to make obligatory this mass radiological detection programme during the fourth month of life, this would necessitate a serious effort to train all radiologists to obtain adequate films with the best radiation protection.
    Type of Medium: Electronic Resource
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