ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Cyclization Reactions of β,γ-Unsaturated Derivatives of Carbonic Acid. IV. Synthesis of N-Substituted Thiazolidine-2-ones and 2-Alkoxy-2-thiazolines from β,γ-Unsaturated Thiocarbamic Acid EstersThe reaction between N-substituted β,γ-unsaturated thiourethans and dry hydrogen chloride or bromine occurs in methylene chloride at room temperature. The thiourethans 1 a-4 a react with hydrogen chloride to give mixtures of corresponding 2-alkoxy-2-thiazolines 6-9 and the thiazolidine-2-one 11 a. A useful synthetic route to N-substituted thiazolidine-2-ones 11 is demonstrated by the reaction of N,N-disubstituted β,γ-unsaturated thiourethans with hydrogen chloride and bromine. The i.r. and H-n.m.r.-data of the compounds are described.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19813230312
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