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  • 1975-1979  (5,717)
  • 1976  (5,717)
  • Chemistry  (5,694)
  • Nuclear reactions
  • pharmacokinetics
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 55-58 
    ISSN: 1432-1041
    Keywords: Penicillin V ; bioavailability ; pharmacokinetics ; dose ranging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary An absorption study was performed in ten healthy volunteers to test the bioavailability of various doses of two penicillin V-K preparations: Isocillin® (Hoechst AG, Federal Republic of Germany), — tablets of 600 000 and 1.2 Mega U; V-Cillin® (Eli Lilly, USA), — tablets of 200 000, 400 000 and 800 000 U. The serum concentrations and elimination of the active substance in urine were measured for six hours after administration. Independently of the source of the preparation, a strict linear relation between the dose and the area under the serum curve (AUC), or between the dose and the urinary elimination, was demonstrated by regression analysis. The dose-dependent increase in the AUC was highly significant (p〈0.01) in the range tested, i.e. between 200 000 and 1.2 Mega U. The relative elimination of active substance in urine lay within narrow limits for all doses (35.7–41.3%). Thus, both compounds proved to have the same bioavailability.
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  • 2
    ISSN: 1432-1041
    Keywords: Ampicillin ; bioavailability ; pharmacokinetics ; branded products ; proprietary preparations ; capsule formulation ; tablet formulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics and bioavailability of three different brands of ampicillin were studied in 10 volunteers. After intravenous administration ampicillin can be described adequately by a two-compartment open pharmacokinetic model. The half-life during the α-phase was 9 min and the β-half-life was in the range 50–60 min, independent of the mode of administration. Absolute bioavailability was determined from the ratio of the areas under the serum concentration curves obtained after oral and intravenous administration of equal doses. Bioavailability was also estimated by analysis of variance. The results indicated absolute availability of the three products of 39–54%. One of the products, a capsule formulation, showed a significantly lower bioavailability than the others, which were tablet formulations.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 257-262 
    ISSN: 1432-1041
    Keywords: Anti-inflammatory and analgesic drug ; indoprofen ; pharmacokinetics ; bioavailability ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In a pharmacokinetic study of the new analgesic and anti-inflammatory drug indoprofen, plasma levels and urinary excretion were determined in four healthy volunteers after 100 mg and 200 mg iv, and after 100 mg (capsules) and 200 mg (tablets) oral doses. After iv administration, the mean biological half-life (t1/2 β) was about 2 h (range 1.4 to 3.2 h). The apparent volume of distribution Vdβ ranged between 11 to 17 % of body weight, indicating its limited extravascular distribution. Most of the drug was excreted in urine as glucuronide and a smaller proportion as unchanged indoprofen: the 24 h urinary excretion of these compounds accounted for 67 to 95 % of an iv dose. Peak plasma levels occurred between 30 and 120 minutes after oral administration of 100 mg as capsules or 200 mg as tablets. The mean biological half-life was about 2 h, as after iv administration. The bioavailability of oral doses was assessed using both plasma levels and urinary excretion data. The absorption of capsules and tablets was practically complete, that of the former being faster.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 263-271 
    ISSN: 1432-1041
    Keywords: Butobarbital ; pharmacokinetics ; plasma concentration ; oral administration ; accumulation ; enzyme induction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A method is described for the assay of therapeutic levels of butobarbital (5-ethyl-5-n-butylbarbituric acid) in human plasma, which involves a single extraction step followed by gas chromatography with alkali flame ionization detection. The pharmacokinetics of butobarbital were studied in five healthy volunteers after oral administration of 200 mg. Plasma concentrations were determined at regular intervals up to 96 h and the data were fitted by non-linear, least squares regression analysis according to one-compartment kinetics. The average lag time was 0.11 h and the absorption half-life 0.21 h. The elimination half-life varied from 33.6 to 41.5 h with an average of 37.5 h. Four of the volunteers participated in a study of multiple dosing (every 24 h) during which substantial accumulation of butobarbital was observed. The elimination half-life after termination of drug administration had decreased to about 20–25% of its initial value, probably because of enzyme induction. It was concluded that butobarbital could not be regarded as a suitable drug for treatment of insomnia, since CNS depressant effects were likely to persist into the following day. Repeated administration of butobarbital should be avoided and its incidental use restricted to patients who require day-time sedation.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 293-295 
    ISSN: 1432-1041
    Keywords: Bendroflumethiazide ; diuretics ; GLC ; thiazides ; plasma level ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A GLC method for determination of bendroflumethiazide has been developed, using extractive methylation. Cyclopenthiazide was used as internal standard. The maximal plasma concentration (56–107 ng/ml) after bendroflumethiazide 10 mg given orally to four healthy volunteers was seen at 2–2.5 h. On the slope between 4 and 10 h T1/2 averaged 2.7 h.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 337-341 
    ISSN: 1432-1041
    Keywords: Amitriptyline ; pharmacokinetics ; intravenous infusion ; two compartment model ; biological half-life
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Amitriptyline was given to four male volunteers by constant rate intravenous infusion. Blood samples were collected before, during and at various times after the infusion for estimation of the serum concentrations of amitriptyline. The level of nortriptyline never reached a detectable level. A two compartment open model was shown to be applicable to the data obtained. The meaning of the parameters obtained by a non-linear, least squares curve fitting procedure is discussed and the values are compared to those recently published for nortriptyline. The calculated biological half-life of amitriptyline was about 17 hours, a figure which differs considerably from previously calculated values for volunteers, but is in accordance with some newer results from patients.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 63-68 
    ISSN: 1432-1041
    Keywords: Phenazone ; pharmacokinetics ; injuries ; surgery ; operation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The elimination rate of phenazone after a single oral dose has been studied before and after elective operations. In a group of patients with different illnesses the elimination rate was increased on the fourth to seventh days after operation but was unchanged on the second and third days. The change in elimination rate was highly significant in a standardized group of nine patients with a ligament injury in one knee studied on the fourth or fifth postoperative day. Possible reasons for the changes are discussed.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 251-256 
    ISSN: 1432-1041
    Keywords: Sisomicin ; pharmacokinetics ; bioavailability ; two-compartment analysis ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of sisomicin, a new single component aminoglycoside antibiotic related to gentamicin c1a, were determined in four healthy volunteers after intravenous and intramuscular administration of a 1 mg/kg dose. The elimination profile of this antibiotic follows two-compartment model kinetics after I.V. administration. The fast (α) and slow (β) disposition rate constants averaged 0.072 and 0.004 min−1, respectively. The volume of distribution at the steady-state averaged 0.185 liters/kg which approximately corresponds to the volume of extracellular space. The physiological availability of an intramuscular dose appeared to be complete. A method of administration adapted to the kinetic properties of the drug is proposed.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 183-187 
    ISSN: 1432-1041
    Keywords: Hydralazine ; bioavailability ; pharmacogenetics ; first pass effect ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary After oral administration of a single 50 mg dose of hydralazine (Apresoline®), the serum half-life (T1/2) and bioavailability (AUC0−∞) were assessed in 16 healthy volunteers. The half-life was 2.57±0.14 h (S.E.) in 10 slow acetylators of sulphadimidine, and 2.18±0.15 h in 6 fast acetylators (difference not statistically significant). AUC0−∞ was significantly higher in slow acetylators, at 1.04±0.10 µg·hour·ml−1, compared to 0.66±0.12 µg·hour·ml−1 in the fast acetylators (p〈0.025). Treatment with Apresoline® 25 mg tid produced minimum serum concentrations at steady-state of 57.3±7.3 ng·ml−1 and 33.4±4.2 ng·ml−1 in 8 slow and 5 fast acetylators, respectively (p〈0.05). The corresponding maximum concentrations were 228.8±20.3 ng·ml−1 and 147.6±15.0 ng·ml−1 in slow and fast acetylators, respectively (p〈0.025). First-pass metabolism of hydralazine could explain the difference in bioavailability of the drug between fast and slow acetylators, without any corresponding difference in the elimination rate of the drug in the post-distributive phase.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 121-126 
    ISSN: 1432-1041
    Keywords: Diazepam ; pharmacokinetics ; subchronic dosage in man ; desmethyldiazepam
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In seven healthy male volunteers the effects of the pattern of dosing on the pharmacokinetics of diazepam have been studied. A cross-over design was employed that consisted of three parts: a single intravenous dose (0.1 mg/kg), and oral dosing (10 mg/day) for six days followed by an intravenous bolus (0.1 mg/kg) on the seventh day, followed by re-examination of a single intravenous dose after diazepam (D) and its major metabolite desmethyldiazepam (DD) had been completely eliminated. Plasma levels of D and DD were monitored by a specific, sensitive GLC-method. In younger patients (n=5, age 29 – 35 years) the elimination half-life, T1/2 (β), of D was 33.9±10.6 h (mean±S.D.) after the single dose. The control study gave an almost identical result (35.7±12.1). After subchronic dosage in all patients T1/2 (β) showed a modest but significant prolongation (paired t-test p〈0.01) to 52.9±17.4 h. It was caused by a significant decrease (p=0.016) in total plasma clearance ( $$\overline {\user1{Cl}} $$ ), from 26.0±10.8 ml/min to 18.2±7.0 ml/min. Older patients (age 43–60 years) showed the same phenomenon. Blood/plasma ratios remained constant indicating no change in protein binding. Biliary excretion of D was measured in five patients with a T-tube. Only negligible amounts (0.3–0.4%) of administered D were excreted within 3 days after subchronic dosage, which demonstrates a lack of enterohepatic cycling of D. After multiple administration of D, there was accumulation of DD to levels approximately five times higher than after a single dose. The possibility that the slower elimination of D after subchronic treatment might be caused by DD was also supported by experiments in dogs and rabbits. After pretreating rabbits with DD and maintaining a high DD plasma level, there was prolongation of T1/2 (β) from 2.7 h to 5.2 h, with a corresponding decrease of $$\overline {\user1{Cl}} $$ from 101.6 ml/min to 23.4 ml/min. Similar results were obtained in dogs. It is concluded that the disposition of D is altered by subchronic use and may be regulated by the plasma DD concentration.
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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 311-317 
    ISSN: 1432-1041
    Keywords: Hydralazine ; instability of impaired renal function ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Following a single 50 mg dose of hydralazine (Apresoline®) in 13 patients with impaired renal function, a decrease in glomerular filtration rate (GFR) was correlated with an increase in serum half-life (T1/2) of the drug (r=−0.69; p〈0.01). The T1/2 was 15.8 h in one patient with a GFR of 16 ml·min−1, as compared to a T1/2 of 1.7–3.0 h found previously in 16 healthy volunteers. In 49 patients on long-term antihypertensive treatment with hydralazine, the ratio between the minimum steady-state drug concentration and the daily dose of hydralazine (C SS min : Dose) increased as the GFR decreased. This accumulation of the drug was particularly evident in patients with a GFR less than 30 ml·min−1 (r=−0.63; p〈0.01; n=19). As renal excretion of unchanged hydralazine is generally regarded as unimportant, the slower elimination rate in chronic renal failure was probably caused by a slower rate of metabolic conversion. It was found, however, that the renal excretion of hydralazine could easily have been underestimated, as only 12.7% of an initial hydralazine concentration of 200 ng·ml−1 in urine could be recovered after storage of the samples at room temperature for 24 h.
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 325-330 
    ISSN: 1432-1041
    Keywords: Flutiorex ; pharmacokinetics ; sex ; anorectic agent ; sympathetic stimulation ; CNS stimulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of flutiorex, a new anorectic agent, and of a placebo on food intake and the activity of the sympathetic and central nervous systems have been compared in a double blind trial in two groups of healthy volunteers, one of five males and the other of five females. Flutiorex 20 mg orally had a significant anorectic effect both in males and females, the observed reduction in food intake being 34.0 and 27.5%, respectively. It caused α-adrenergic stimulation (blood pressure and pupil diameter) and central nervous system excitation (critical flicker frequency), both of which were more marked in males than in females. Flutiorex was better tolerated by women than by men. Measurement of the blood level of flutiorex and its de-ethylated metabolite, norflutiorex, showed that both compounds were detectable in four of the five male subjects, but in only one of the five females. Sex-linked differences in the pharmacokinetics of flutiorex may explain the greater intensity of its effects in males.
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 343-347 
    ISSN: 1432-1041
    Keywords: Methaqualone ; hypnotic ; pharmacokinetics ; combination formulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Concentrations of methaqualone have been measured in the serum of five male human subjects receiving five consecutive evening doses of a combination formulation containing methaqualone (250 mg), carbromal (300 mg) and benactyzine (0.33 mg) in each tablet. After administration of the first dose, mean peak serum concentrations of methaqualone (1.2 µg/ml) occurred at 3 h. After obtaining peak levels, mean concentrations of methaqualone declined rapidly during the next 6 h and there-after more slowly during the next 18 h. After administration of the last (fifth) dose, mean peak serum concentrations of methaqualone (1.9 µg/ml; 1.5 µg/ml above the predose level) occurred at 2 h. After attaining peak levels, mean concentrations of methaqualone declined rapidly during the next 6 h, and thereafter more slowly, with a half-life of approximately 10 h. Mean concentrations of methaqualone in serum samples 24 h after the second, third, fourth or fifth doses were not significantly different (0.3 µg/ml – 0.6 µg/ml) during this period of dosing. This suggests that significant accumulation of methaqualone in the serum did not occur during a period of five consecutive evening doses of the combination formulation.
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 25-29 
    ISSN: 1432-1041
    Keywords: Digoxin ; exchange transfusion ; pharmacokinetics ; neonates ; 86Rb assay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary By means of an86Rb-uptake inhibition assay, changes in the plasma concentration of digoxin and the amount of the glycoside removed during exchange transfusion have been studied in two newborns. For comparison, the exchange procedure was simulated by a computer on the basis of a two-compartment open model and available pharmacokinetic constants. A rapid decrease in plasma digoxin concentration during exchange transfusion was found when the glycoside was administered intravenously or intramuscularly within 60 min before the procedure. The amount of digoxin removed by the exchange was less than 6 per cent of the given dose. Computer simulation of the procedure also showed removal of only a minor amount of digoxin. It is concluded that the decrease in plasma concentration and the removal of only a small amount of glycoside by the exchange transfusion can be attributed mainly to extensive tissue distribution of digoxin. The results imply that replacement of digoxin after an exchange transfusion seems unnecessary.
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  • 15
    ISSN: 1432-1041
    Keywords: Diabetes mellitus ; drug interaction ; phenprocoumon ; pharmacokinetics ; pharmacodynamics ; sulphonylureas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The influence of various antidiabetic treatments on the kinetics and efficacy of a single oral dose of 12 mg phenprocoumon were studied in 71 hospitalized patients, 58 with adult-onset diabetes mellitus and 13 non-diabetic aged patients, and 13 healthy young volunteers. Treatment for one week or longer with insulin or the antidiabetic sulphonylureas tolbutamide, glibenclamide or glibornuride, altered neither the plasma level (1.29 – 1.40 µg/ml at zero time) nor the half-life of phenprocoumon (5.2 – 6.8 d) compared to treatment by diet alone. The mean half-life of phenprocoumon was significantly shorter in non-diabetic aged patients (4.2 d) than in diabetic patients of the same age (5.1 – 6.8 d), or in young healthy volunteers (5.7 d). The efficacy of a single dose of phenprocoumon (maximal reduction of Quick-values by 34 – 47% after 48 to 72 hrs) in diabetic patients treated with diet, or diet and antidiabetic drugs, was the same as in non-diabetic aged patients. In healthy young volunteers phenprocoumon was half as effective as in aged patients.
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 9 (1976), S. 327-332 
    ISSN: 1432-1041
    Keywords: Antipyrine ; pharmacokinetics ; half-life ; blood ; plasma ; saliva ; individual variation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A previously described GLC method has been modified and applied to measurement of antipyrine levels in plasma, blood and saliva of man following administration of a single oral dose (10 mg/kg). The levels in blood and saliva were comparable to those in plasma at every time studied. The half life of antipyrine determined in blood, plasma or saliva in any given individual was similar. The intersubject variation in half-life was about two-fold (n=5). Antipyrine levels in saliva were not affected by the rate of saliva flow when collections were made continuously for 20 minutes. This study has demonstrated that kinetic data about antipyrine comparable to that from plasma may also be obtained from readily accessible tissue fluids, such as saliva and capillary blood.
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  • 17
    ISSN: 1432-1041
    Keywords: Chlorthalidone ; diuretics ; drug plasma concentration ; protein binding ; red blood-cell concentration ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A gas chromatographic method has been employed to determine chlorthalidone in plasma and whole blood after therapeutic doses. Radioactively labelled chlorthalidone was used for in vitro studies of the uptake of chlorthalidone from plasma by red blood cells. Chlorthalidone was markedly concentrated in red cells and as a compartment they would account for at least 30% of total drug in the body after multiple doses. The ratio between the plasma and red cell concentration of chlorthalidone varied between individuals. After a single oral dose of 50 mg in 6 healthy volunteers chlorthalidone was eliminated with a half-life of 51 to 89 hours. The apparent volume of distribution varied between 3 and 13 1/kg and the clearance between 53 and 145 ml/min. The mean steady-state plasma concentrations during treatment with a standard dose of 50 mg daily (n=10) varied 5-fold between individuals. During the steady state approximately 50% of the daily dose was excreted unchanged in the urine during 24 hrs. The plasma levels observed in patients were higher than those predicted from the single oral dose studies in healthy volunteers.
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  • 18
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 9 (1976), S. 367-372 
    ISSN: 1432-1041
    Keywords: Sotalol ; β-adrenoceptor blocking drugs ; exercise tachycardia ; efficacy ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of sotalol after oral administration were measured on the tachycardia induced by strenuous exercise in normal subjects. Plasma sotalol levels were also determined. The oral administration of sotalol (50, 100, 200 and 400 mg) to 6 subjects produced a progressive reduction in the tachycardia induced by severe exercise. This was similar to the effects of 25, 50, 100, 200, 400 and 800 mg given to different subjects. Each increase in sotalol dose produced a successively greater reduction in exercise tachycardia. This did not appear to be maximum even with 800 mg. Oral sotalol was rapidly absorbed and produced peak blood levels in 2 – 3 hours. The plasma levels of sotalol measured 2 hours after the oral administration of 25 to 800 mg showed never more than a six-fold variation between different subjects. The half-life of sotalol in plasma was 12.7 ± SE 1.6 hours. There was a significant correlation between the logarithm of the plasma sotalol concentration and the percentage reduction of exercise heart rate. It is concluded that the oral administration of sotalol either once or twice daily (depending on dose level) will provide satisfactory 24-hour blockade of β-adrenoceptors.
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  • 19
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    Electronic Resource
    Springer
    European journal of clinical pharmacology 9 (1976), S. 443-450 
    ISSN: 1432-1041
    Keywords: Cyclobarbital calcium ; pharmacokinetics ; plasma concentration ; relative bioavailability ; oral administration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics and relative bioavailability of cyclobarbital calcium have been studied after oral administration of Phanodorm, of tablets according to the Formularium Nederlandse Apothekers (1968; FNA), and an aqueous solution. Six healthy volunteers participated in the investigation on three occasions and each received the three preparations. The dose administered was 300 mg cyclobarbital calcium. Plasma concentrations of cyclobarbital were determined at regular intervals. Absorption from the three preparations was rapid and was faster from the solution. Peak concentrations were usually attained within 1 h. The elimination of cyclobarbital could be described by a single first-order process with an average half-life of 11.6 h (range 8 – 17 h). There was little intra-subject variation of the half-life. Relative bioavailability for each volunteer was estimated by comparing the areas under the plasma concentration curves. The FNA-tablets and Phanodorm exhibited similar bioavailability, whereas the average bioavailability of the solution was 78% of that of FNA-tablets; the reason for this unexpected finding is unknown. It was concluded that cyclobarbital cannot be regarded as a uniformly suitable drug for the treatment of insomnia. The long half-life that was apparent in some of the volunteers (15 – 17 h) creates a substantial risk of residual effects on the following morning. In principle, however, the calcium salt of cyclobarbital may be used for induction of sleep, because of its rapid absorption.
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  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 4 (1976), S. 199-230 
    ISSN: 1573-8744
    Keywords: disopyramide ; antiarrhythmic ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The pharmacokinetics of the antiarrhythmic disopyramide, 4-diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide phosphate, and its monodealkylated metabolite were investigated in seven volunteers after intravenous (1 and 2 mg/kg) and oral (3 and 6 mg/kg) administration. Unchanged drug (52%) and the monodealkylated metabolite (25%) were renally excreted on intravenous administration. The pharmacokinetics of disopyramide were first order and dose independent only when referenced to the drug not bound to plasma proteins since this binding was dose dependent. The apparent half-lives of the α and β phases on intravenous administration were 2 min and 4.5 hr, respectively. The apparent volumes of distribution of the central and peripheral compartments, referenced to unbound disopyramide in the plasma, were 9 and 80 liters, respectively. The half-life of absorption of oral aqueous disopyramide phosphate was 30 min with a lag time of 16 min and an apparent first-pass metabolism of 16% of the absorbed dose, consistent with the hepatic efficiency of 14%. The renal and metabolic clearances were 125 and 111 ml/min, respectively. Graphical and computer analysis of the plasma and urine data showed dose-independent first-order pharmacokinetics of plasma unbound drug in a two-compartment-body model to give two metabolites and a first-pass transformation of a fraction of the oral dose. The absorption efficiency of unchanged drug was 83%.
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  • 21
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 4 (1976), S. 337-353 
    ISSN: 1573-8744
    Keywords: bioavailability ; pharmacological data ; pharmacokinetics ; modeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The use of data deriving from monitoring the time variation of the intensity of pharmacological effect(s) following dosing can often present an advantageous alternative to the more conventional approach of using chemical or radiological assay of blood and/or urine level data for bioavailability evaluations of drug products: bioavailability studies can be performed with drugs where no assay exists. A relatively simplified discussion of the general theoretical principles on which the use of pharmacological data is based and a stepwise description of the approach for its routine application in bioavailability studies are presented. Approaches for computing rates and extents of drug bioavailability vs. time profiles on analog and digital computers are qualitatively described and quantitatively presented in a subsequent report. The concept of preabsorption (gastrointestinal bioavailability) is introduced and biophasic availability of drugs to local sites of action is discussed.
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  • 22
    Electronic Resource
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    Springer
    Journal of pharmacokinetics and pharmacodynamics 4 (1976), S. 355-375 
    ISSN: 1573-8744
    Keywords: deconvolution ; bioavailability ; pharmacokinetics ; modeling ; pharmacological data
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Mathematical expressions and approaches to the computation of rates and extents of drug bioavailability for implementation on analog and digital computers are derived. The equivalency of expressions derived on the basis of assuming compartment models to an approach based on using experimentally determined weighting functions is demonstrated. The relative merits of the two techniques are discussed: their application for use with temporal pharmacological data is emphasized. The applicability of the computational techniques to determining the availability of drugs at local sites of action (biophasic availability) and to computing preabsorptive drug release into the gastrointestinal contents (gastrointestinal bioavailability) is pointed out. An approach to computationally predicting in vivo blood level or pharmacological response vs. time profiles from in vitro dissolution testing results is presented and its limitations are discussed.
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  • 23
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 1-1 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 24
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Testing of flanged joints in GRP pipelines of 200 mm nominal diameter by means of short-term and long-term stressing. Part I: Sealing behaviour. The first part of this report deals with the sealing behaviour of joints with fixed and loose flanges in GRP pipelines of 200 mm nominal diameter. Tests were made with seven different flanges from three manufacturers and four different types of sealing rings. At room temperature the spring rate of the GRP flanges amounted to between 8% and 18% of that of welded steel flanges and at a temperature of 80°C within the pipe it was 5% to 16% of that of the steel flanges. Of the sealing rings tested a bulged soft rubber ring with steel reinforcement was found to have the flattest resilience characteristic and required the least bolt force to produce a tight joint under operational conditions. Its relaxation rate was low after low bolt force had been applied and increased rapidly when the initial bolt force was increased to higher values. Because of their lower spring rates, the GRP flanges sealed with this ring required 2.5 to 3.5 times as much initial bolt force as welded steel flanges. In an 1100-hour creep test at 80°C internal temperature and 10 bar internal pressure, a joint consisting of loose steel flanges and GRP shoulders exhibited considerably less loss of initial force than a fixed GRP flanged joint. Because losses of initial force increase at a disproportionately high rate as the force is raised, high initial force would not seem to increase remarkably the reliability of the seal in the long term. Since rigid flanges require less initial force than less rigid ones, high spring rate appears desirable. Apparently it could best be achieved by loose steel flanges with GRP shoulders. The results of the strength tests will be presented in the second part of this report.
    Notes: Der erste Teil dieser Arbeit befaßt sich mit dem Dichtverhalten von GFK-Fest- und -Losflanschen NW 200 dreier Hersteller sowie von vier verschiedenen Dichtungen. Die Federrate der GFK-Flansche betrug bei Raumtemperatur 8% bis 18% und bei 80°C Innentemperatur 5% bis 16% der Federrate von Vorschweißflanschen aus Stahl. Von den untersuchten Dichtungen hatte eine ballige Weichgummidichtung mit Stahleinlage die flachste Kennlinie und benötigte die niedrigste Betriebsdichtungskraft. Ihre Relaxationsgeschwindigkeit war bei niedrigen Dichtungskräften gering und nahm bei höheren Kräften stark zu. Die GFK-Flansche erforderten wegen ihrer geringeren Federrate mit dieser Dichtung eine 2,5- bis 3,5mal höhere Vorspannkraft als Stahl-Vorschweißflansche. In einem 1100-h-Zeitstandversuch bei 80°C Innentemperatur und 10 bar Innendruck des Prüfkörpers hatte eine GFK-Losflanschverbindung mit Stahlringen wesentlich geringere Vorspannungsverluste als eine GFK-Festflanschverbindung. Wegen der mit der Dichtungskraft überproportional steigenden Vorspannungsverluste dürften hohe Vorspannkräfte die Sicherheit gegen Leckwerden auf Dauer wenig erhöhen. Da steife Flansche eine geringere Vorspannung als weniger steife benötigen, erscheint eine hohe Federrate erstrebenswert. Sie dürfte sich am ehesten bei Losflanschen aus Stahl mit GFK-Bunden erreichen lassen. Die Ergebnisse der Festigkeitsuntersuchungen werden im zweiten Teil dieser Arbeit mitgeteilt.
    Additional Material: 11 Ill.
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  • 25
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 38-48 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Identification of X-Ray powder diffraction patterns with the mini-computer. A description is given of a programme for identifying X-ray diffraction patterns of multiphase, polycrystalline materials with the minicomputer Wang 720 C. It is determined by the identification strategy, the identification criterion and the Δd(d) function which describes the permissible variation between the measured d values and those laid down in accordance with ASTM material data cards in the magnetic tape file. In the course of these investigations the partially erroneous and often also incomplete information provided by this file in respect of relevant material data proved in particular to be the decisive factor for the limitation of the reliability of the identification result.The efficiency of the programme is demonstrated by means of characteristic examples. In conclusion, the prospects for the future development of this programme are discussed.
    Notes: Es wird ein Programm zur Identifikation von Röntgenbeugungsdiagrammen mehrphasiger, polykristalliner Stoffe mit dem Tischcomputer Wang 720 C beschrieben. Seine bestimmenden Größen sind die Identifikationsstrategie, das Identifikationskriterium und die Δd(d)-Funktion, die die zulässige Abweichung zwischen den gemessenen und den in der Magnetband-Datei nach ASTM-Stoffdatenkarten festgelegten d-Werten vorgibt. Im Verlauf dieser Untersuchungen erwiesen sich insbesondere die z. T. fehlerhaften und nicht selten auch unvollständigen Angaben dieser Kartei bei relevanten Stoffdaten als der entscheidende Faktor für die Begrenzung der Zuverlässigkeit des Identifikationsergebnisses.An charakteristischen Beispielen wird die Leistungsfähigkeit des Programms demonstriert. Abschließend wird ein Ausblick auf die Weiterentwicklung dieses Programms gegeben.
    Additional Material: 2 Ill.
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  • 26
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 123-123 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 27
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 28
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 123-123 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 29
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 123-123 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 30
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 124-124 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 31
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A67 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 32
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Tests on influence of shape to structural member toughness. Supplementary to former work on temperature depending toughness of boiler plate and low temperature steel vessels, influences of shape and manufacturing are investigated with model vessels of a different design, made of boiler plate. The expected influences seem to be evident only with regard to bursting behaviour of the vessels depending on temperature, whilst toughness behaviour may be estimated - without dependence on shape - by materials property data (crack arrest temperature and impact transition temperature).
    Notes: Ergänzend zu früheren Arbeiten über die temperaturabhängige Zähigkeit von Modellbehältern aus Kesselblech und aus Tieftemperaturstahl werden hier an Behältern anderer Konstruktionsform aus Kesselblech zusätzlich Einflüsse der Gestaltung und der Fertigung untersucht. Dabei zeigt sich, daß diese Einflüsse sich offenbar nur auf die Haltbarkeit der Behälter und den Verlauf des Berstdrucks über der Temperatur auswirken, daß aber die Verformungsreserve und damit das Zähigkeitsverhalten unabhängig davon aufgrund von Werkstoffkennwerten (Rißauffangtemperatur und Kerbschlagübergangstemperatur) abgeschätzt werden kann.
    Additional Material: 9 Ill.
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  • 33
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 314-315 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 34
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: The Mechanical Compatibility of Composite Components. The mechanical interactions between the components of a composite material are governed by the elastic constants, the strength and the plastic deformation behavior of the components. They can be furthermore influenced by the coefficients of thermal expansion and by the bond strength between the components. The extent of mechanical compatibility depends on the structure of the composite material and on its processing technique and practical application. This paper gives an introduction to a series of papers on the mechanical compatibility presented in a workshop meeting at Konstanz.
    Notes: Die Mechanische Verträglichkeit bewertet das Verhalten von Materialkomponenten in einem Verbundsystem. Die mechanischen Wechselwirkungen bei Verbundwerkstoffen werden einerseits durch die elastischen Konstanten, die Festigkeit und das plastische Formänderungsvermögen der einzelnen Komponenten bestimmt und andererseits durch Unterschiede in den thermischen Ausdehnungskoeffizienten und durch die Haftfestigkeit zwischen den Komponenten festgelegt. Bei der Beurteilung der mechanischen Verträglichkeit spielt die Art des Verbundwerkstoffs und der äußeren Beanspruchung eine wesentliche Rolle. Diese Arbeit gibt eine Einführung in die Probleme der mechanischen Verträglichkeit, die in einem Workshop der Deutschen Gesellschaft für Metallkunde in den Themenkreisen Grundlagen, Meßmethoden und Beeinflussung des Werkstoffverhaltens ausführlich behandelt werden.
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  • 35
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 316-316 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 36
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 323-325 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 37
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 332-333 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 38
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 338-340 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 2 Ill.
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  • 39
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 340-343 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Mechanical compatibility of metallic composites. Corrosion in aqueous media. As a main condition for corrosion in aqueous media between components of a composite material, both components have to be touched by an invironmental wed atmosphere or of a fluid. If this condition is given contact corrosion can take place with any composite, independent of the mechanical compatibility of the components. Crevice corrosion is possible too if mechanical incompatibility (or extern loads) causes cracks between the components; stress corrosion cracking is possible as well. Stainless steel vires, for instance, can not reinforce the composit if attached by SCC. The other kinds of corrosion mostly dammage the matrix, which also reduces properties of the composit.Examples are given of possible kinds of corrosion for some fiber reinforced metallic composites and for metal laminates.
    Notes: Das Auftreten von Naßkorrosion zwischen den Komponenten eines Verbundwerkstoffs setzt voraus, daß beide Komponenten der umgebenden feuchten Atmosphäre oder einer umgebenden Flüssigkeit zugänglich sind. In diesem Fall kann bei jedem metallischen Verbund - faserig, lamellar oder geschichtet - und unabhängig von der mechanischen Verträglichkeit Kontaktkorrosion ausgelöst werden. Entstehen durch Unverträglichkeit (oder durch äußere Einflüsse) Risse, so kann Spaltkorrosion hinzukommen; und bei Eigenspannungen, wie auch bei äußeren Spannungen, kann Spannungsrißkorrosion beobachtet werden, sofern eine der Komponenten dagegen anfällig ist. Austenitische Stahldrähte z. B. neigen zu SpRK und können damit ihren Verstärkungseffekt einbüßen. Auch die anderen Korrosionsarten, die meist zu Lasten des Matrix- oder Grundwerkstoffs gehen, mindern in jedem Fall die Eigenschaften des Verbundes.Für einige Beispiele heute gebräuchlicher Verbundwerkstoffe werden die möglichen Korrosionsarten tabellarisch zusammengestellt.
    Additional Material: 3 Tab.
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  • 40
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 353-356 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 5 Ill.
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  • 41
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A107 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 42
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 364-367 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Determining the moduls of elasticity from the compliance of precracked specimens. A new method is described which allows the determination of the modulus of elasticity of solid materials. Compliance tests with precracked fracture mechanics specimens in a simple tensile test machine yield accurate measurements of the modulus of elasticity in the orientation and material condition desired for fracture mechanics calculations.
    Notes: Es wird über ein neues Meßverfahren berichtet, den Elastizitätsmodul von Werkstoffen zu bestimmen. Es ist an einfachen Zerreißmaschinen durchzuführen und gibt Meßwerte des Elastizitätsmoduls in der für bruchmechanische Untersuchungen gewünschten Probenorientierung, Materialbeschaffenheit und Genauigkeit.
    Additional Material: 3 Ill.
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  • 43
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 376-380 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: The Influence of Porosity on a Few Properties of Tungsten/Copper Contact Materials. An investigation has been carried out on the influence of the amount of residual porosity on the electrical and mechanical properties of infiltrated tungsten/copper materials. By means of adding different quantities of infiltrating metal materials with a tungsten content of approximately 70 wt.% containing between 0,2 and 30% pores were produced. The following properties were measured for the different material specimens: are erosion rate, electrical conductivity, Vickers hardness number, and notch impact toughness. The arc erosion rate is not noticeably increased by pore contents up to 4%, all the other properties, however, are influenced considerably even by the smallest amount of measurable residual porosity. Thus it has to be concluded that infiltration with a slightly smaller quantity of infiltrating metal than that necessary to attain a pore-free material - a technique used occasionally in order to avoid the necessity of finishing the infiltrated parts - will lead to changes in quality.
    Notes: Es wird die für die praktische Fertigung von W/Cu-Tränkwerkstoffen wichtige Frage untersucht, inwieweit Restporositäten von Einfluß auf die elektrischen und mechanischen Eigenschaften sind. An Werkstoffen mit ca. 70 Gew.% Wolfram werden durch abgestufte Tränkmetallzugaben unterschiedliche Porositäten zwischen 0,2 und ca. 30% eingestellt und die Eigenschaften Abbrandverhalten im Hochstromlichtbogen, elektrische Leitfähigkeit, Vickershärte und Kerbschlagzähigkeit gemessen. Während Restporositäten bis zu 4% noch keine Erhöhung des Abbrandes bewirken, zeigen die übrigen Eigenschaften schon von kleinsten Porenanteilen an einen deutlichen Abfall. Die manchmal angewandte Fertigungsweise, durch geringe Unterschußtränkung eine mechanische Nachbearbeitung der Tränkteile zu vermeiden, ist mit den im Bericht aufgezeigten Qualitätsänderungen verbunden.
    Additional Material: 5 Ill.
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  • 44
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 390-391 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 2 Ill.
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  • 45
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 392-392 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 46
    Electronic Resource
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 47
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 409-413 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Cavitation-Corrosion - Types of Damage on the Surface of Pure Aluminium. By scanning electron microscope studies the development and propagation of plastic deformation and other types of damage are investigated.
    Notes: Mit Hilfe des Rasterelektronenmikroskopes werden die Ausbildung und der Fortschritt einer Werkstoffschädigung von Reinaluminium bei Kavitationsbeanspruchung studiert.
    Additional Material: 5 Ill.
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  • 48
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Clad Metals for Electrical Engineering. Materials with optimum properties for conducting springs can be produced by cladding a metallic sheat of high electrical conductivity between two sheats of a metal with high stiffness.Using suitable cladding components, thermo bi metals with different electrical resistance can be produced without essential variation of deflection and force. With this it is possible, to use groups of devices with uniform mechanical construction for different currents, which means a good technical as well as economic solution.High prices of noble metal based contact materials have led to the production of contact bimetals some years ago. Inspite of higher production costs these materials can be used very economically.
    Notes: Durch geeignete Anordnung hochfester und hochleitfähiger Komponenten in einem Schichtverbundwerkstoff lassen sich Werkstoffe mit optimalen Eigenschaften für stromführende Federn herstellen. Durch Verwendung geeigneter Plattierungskomponenten können Thermobimetalle mit unterschiedlichem elektrischen Widerstand ohne wesentliche Veränderung der Ausbiegung und der Kraftwirkung hergestellt werden. Somit ist es möglich, Gerätegruppen mit gleichem mechanischen Grundaufbau für verschiedene Stromstärken zu verwenden und damit technisch und wirtschaftlich günstige Problemlösungen zu erzielen.Der hohe Preis der Kontaktwerkstoffe auf Edelmetallbasis führte schon vor vielen Jahren zur Herstellung von Kontaktbimetallen. Trotz höherer Formkosten sind diese Werkstoffe in den meisten Fällen besonders wirtschaftlich einsetzbar.
    Additional Material: 5 Ill.
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  • 49
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A126 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 50
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 51
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 429-437 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Investigations on long term strength of thermoplastic tubes in chemical media. Mechanical long term behaviour of plastics is influenced by environmental media, similar to stress corrosion cracking of metals. Therefore chemical resistance is not to be seen only by immersion tests but has to be found by long term tests under both, mechanical and chemical loading. The paper deals with a test method which shows shortening of the time for rupture of small tube specimens loaded by internal pressure after being filled with the medium.Examples are given for interpretation of results obtained in an international test program.
    Notes: Ähnlich der Spannungsrißkorrosion bei Metallen beobachtet man bei Kunststoffen unter Einwirkung chemischer Agenzien eine Änderung des zeitabhängigen Festigkeitsverhaltens. Zur Beurteilung der chemischen Beständigkeit sollte daher das Ergebnis von Immersionsversuchen nur für eine Vorauswahl herangezogen werden, während für die konstruktive Verwendung die Zeitstandfestigkeit in dem Umgebungsmedium ermittelt werden muß. Hierfür wird ein Prüfverfahren gezeigt, das mit Hilfe von Rohr-Innendruckversuchen an kleinen Probekörpern die Standzeitverkürzung durch das Medium erkennen läß; als Bezugsgröße wird die Zeitstandfestigkeit in Wasser bei der betreffenden Prüftemperatur herangezogen. Ist eine Wasserkurve noch nicht vorhanden oder liegt die vollständige Zeitstandkurve für das Medium noch nicht vor, so kann aus den Langzeitversuchen immerhin eine Abschätzung der Lebensdauer und eine Entscheidung über die Verwendbarkeit des Kunststoffes in dem Medium getroffen werden. Anhand von Beispielen aus einem auf internationaler Basis angelegten Untersuchungsprogramm werden der Aussagewert der Prüfmethode und die Interpretationsmöglichkeit dargelegt.
    Additional Material: 15 Ill.
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  • 52
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 452-452 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 53
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 54
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 55
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A83 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 56
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A88 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 57
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 236-240 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Thermal stresses in thick-walled structures. The thermal stresses in typical components of chemical apparatus (plate, cylindrical shell) are calculated for nonuniform temperature distribution. The „exact“ results of the three-dimensional theory obtained by finite element method are compared with the results of the classical theories for thin structures. It is recognizable when an extensive analysis is necessary and when the stresses may be calculated by the relatively simple equations of thin structures theory.
    Notes: Für typische Bauteile des Apparatebaus (Scheibe, Platte, Schale) wurden die Wärmespannungen infolge ungleichmäßiger Temperaturverteilung mit Hilfe finiter Elemente berechnet. Diese „exakten“ Ergebnisse der dreidimensionalen Theorie werden mit den Werten verschiedener Näherungstheorien verglichen. Damit wird erkennbar, in welchen Fällen man umfangreiche Rechnungen durch führen muß bzw. wann die Spannungen aus einfachen Näherungsformeln gewonnen werden können.
    Additional Material: 10 Ill.
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  • 58
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 261-266 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 59
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A128 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 60
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A131 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 61
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Transkristalline Spannungsrißkorrosion an mechanisch überarbeiteten Schweißnähten und Lochfraß im Bereich von Schweißzunder können durch eine angepaßte Beizbehandlung vermieden werden. Unter Schweißzunder, welche beim Beizen zwar gelockert aber nicht entfernt wurde, entsteht bei der anschließenden Spülung mit Wasser schon eine gute Passivschicht, so daß an schwer zugänglichen Stellen auf eine mechanische Beseitigung des noch lose anhaftenden Zunders verzichtet werden kann. Auch sand- und kugelgestrahlte Flächen müssen in der Regel nachträglich gebeizt werden, wenn eine gute Passivität erforderlich ist. Anlauffarben zeigende Flecken auf den Nähten längsgeschweißter Rohre sind für Lochfraß bevorzugt anfällig und müssen gegebenenfalls durch Beizen entfernt werden. Die spaltbehafteten Rohreinschweißungen an Rohrbündel-Wärmeaustauschern lassen sich normalerweise nicht sicher beizen. Dem diesbezüglichen Vorteil der spaltfreien Rohreinschweißung steht bei verschiedenen Stahlqualitäten der Nachteil gegenüber, daß unter den erforderlichen Schweißbedingungen ein Netzwerk aus δ-Ferrit auftritt. Auch die niedrig gekohlten, stickstofflegierten Stähle sind nicht ganz frei von dieser Erscheinung, die sich hier aber stark zurückdrängen läßt, wenn dem Argon-Spülgas etwa 0,5% Stickstoff zugesetzt werden.Schweißnähte können leicht zu Schwachstellen von Chemie-Apparaten werden. Dieser Erfahrung ist bei der Planung, Ausführung und Betreibung von Anlagen Rechnung zu tragen. Das Korrosionsverhalten eines Apparates wird zwar im wesentlichen durch die Auswahl des Grund- und Schweißzusatzwerkstoffes bestimmt, aber erst eine werkstoffgerechte Konstruktion und eine konstruktionsbezogene Verfahrensweise im Betrieb gestatten es, die Möglichkeiten eines Werkstoffes ganz auszuschöpfen. Als Besonderheit kommt bei den nichtrostenden austenitischen Stählen der abschließenden Oberflächenbehandlung des Schweißnahtbereiches eine hohe Bedeutung zu.
    Additional Material: 12 Ill.
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  • 62
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 49-49 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 63
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Rolling Contact Fatigue. Wear, rolling contact fatigue, fatigue - calculation of stresses - stresses caused by normal load - influence of friction - influence of surface roughness - influence of residual stresses - influence of temperature - influence of pressure profile in EHL-contacts - influence of material - influence of lubricants - influence of additives - size effect - investigation of damages.
    Notes: Abgrenzung der Oberflächenermüdung gegenüber Verschleiß und allgemeinen Ermüdungsvorgängen - Beanspruchungsanalyse - Werkstoffanstrengung infolge Normalkraft - Einfluß der konstruktiven Gestaltung - Einfluß der Makroreibung - Einfluß der Oberflächenfeingestalt - Einfluß von Eigenspannungen - Temperatureinfluß - Einfluß des Druckverlaufes unter EHD-Bedingungen - Einfluß von Werkstoff (-Paarung) und Werkstoffzustand - Schmierstoffeinfluß - Einfluß von Schmierstoffbestandteilen - spannungsmechanischer und oberflächentechnischer Größeneinfluß - Vorgehensweise bei der Analyse von Oberflächenermüdungsschäden.
    Additional Material: 19 Ill.
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  • 64
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 97-106 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Investigations on corrosion caused by therm osetting materials (part 2) Electrolytic corrosion. Electrolytic corrosion on metallic materials is caused by plastics under the influence of a direct voltage. This second part of the investigations on plastic corrosion deals with the characteristic qualities of thermosetting materials, responsible for such type of corrosion. These qualities may be determined by the composition of the plastics and by the curring conditions. Measuring the insulation current in the plastic specimen gives an indication to the corrosive effect. It is shown by measuring the insulation current in longtime tests with varying materials and test conditions that short-time tests may give a conclusive statement on the corrosiveness of plastics.
    Notes: Es wird über die an metallischen Bauelementen durch Kunststoffe verursachten Korrosionserscheinungen berichtet, bei denen die Einwirkung elektrischer Gleichspannungen auf die jeweiligen Anordnungen Grundlage des Korrosionsvorganges ist. Dabei wird insbesondere auf die von den Eigenschaften der Kunststoffe bestimmten Parameter eingegangen. Über die Messung der Isolationsströme und Vergleich mit dem jeweils eingetretenen Ausmaß der Korrosion wird die Schlüssigkeit von Kurzzeitversuchen auf die Beurteilung der Korrosionswirkung verschiedener Kunststoffe bei längeren Beanspruchungszeiten untersucht.
    Additional Material: 24 Ill.
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  • 65
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    Materialwissenschaft und Werkstofftechnik 7 (1976) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 66
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 125-128 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Possibilities of producing composites by extremely high deformation. One of the principal problem in the studies of composite-wires with metallic matrix was wether fibre textures of such wires are changed by the contents of second phases or not. An inhibition of the texture development of the matrix occours, if the flow stress of the addition is lower than that of the matrix, and the plasticity of the addition is small, compared with that of the matrix. The mechanism of plastic deformation of the second phase (crystal slip, amorphous flow) is without influence.Preparation of the speciment can be done by solidifiction from the melt, especially combined with directional solidification and furtheron by powder metallurgycal methods.A very high decrease of cross section is connected with the formation of fibres. If the diameter is beneath 1000 Å remarcable anomalies of mechanical and physical properties were observed.The compatibility of the different phases is very good, provided that a high and joint deformation occurs. It is caused by the increase of inner surface during deformation.
    Notes: Ausgangspunkt der Untersuchungen über Verbundwerkstoffe war die Frage, ob und wie sich Verformungstexturen ändern, wenn zweiphasige Legierungen oder Verbundmaterialien mit metallischer Matrix bei gemeinsamer Verformung verändert werden.Eine Beeinträchtigung der Matrixtextur tritt auf, wenn die Fließgrenze des Zusatzstoffes höher liegt als die der Matrix; ferner dann, wenn die Verformungsfähigkeit des Zusatzes geringer ist als die des Matrixmetalls. Die Natur der Formänderung des Zusatzes (kristallografisches Gleiten, amorphes Fließen) ist dabei ohne nennenswerten Einfluß.Herstellungsmöglichkeiten für Verbunddrähte sind über die Schmelze möglich, wobei die gerichtete Erstarrung zunehmende Beachtung findet, ferner auf pulvermetallurgischem Wege.Bei sehr hoher Querschnittsverminderung findet Faserbildung statt. Im Bereich unter 1000 ÅE Faserdicke zeigen sich erhebliche Anomalien einer Reihe von mechanischen und physikalischen Eigenschaften. Die Verträglichkeit der verschiedenen Phasen ist bei gemeinsamer starker Verformung sehr gut. Die Oberflächenvergrößerung bewirkt eine feste adhäsive Bindung.
    Additional Material: 1 Ill.
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  • 67
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 136-138 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Deformation of aluminium composite wires with admixtures of silver-alkali-chlorides. The deformability, the formation of the fibre texture and the tensile strength properties of aluminium compound wires with 5 Vol% saline components of the phase diagramm NaCl-AgCl are investigated. The systematic change of the extended plasticity of the AgCl ionic crystal by alloying with NaCl to the pure NaCl component effects a a penetrating influence of the deformation mechanisms of the aluminium matrix. This fact is obvious by the meaningful change of the fibre texture (110) (111) to complete random orientation of the metallic matrix with increase NaCl portion of the saline solution phase. The excellent plasticity of the pure AgCl-compound produces a fibre structure and a maximum of tensile strength of the fibre like compound wires by fibre reinforcement. With increasing solid solution hardening of the second phase the fibre like shape of the components diminishes. The increment of the strength by pure NaCl compound is caused by dispersion hardening of the aluminium matrix.
    Notes: An Aluminium-Verbunddrähten mit 5 Vol% salzartigen Zusätze des Zweistoffsystems AgCl-NaCl wurden das Formänderungsvermögen, die Fasertexturausbildung und die Festigkeitseigenschaften während des Drahtziehens untersucht. Die systematische Änderung der ausgezeichneten plastischen Eigenschaften des AgCl-Ionenkristalls durch das Legieren mit Natriumchlorid bis zum reinen NaCl-Zusatz bewirkt eine tiefgreifende Beeinflussung des Umformmechanismus der Aluminiummatrix. Dies wird durch die prägnante Änderung der Doppelfasertextur (110) (111) offensichtlich, die mit steigendem NaCl-Gehalt der Ionenmischkristallkomponenten bis zur vollständigen Regellosigkeit abgebaut wird. Die außergewöhnliche Plastizität des reinen AgCl-Zusatzes führt zum faserförmigen Gefügeaufbau und zur maximalen Festigkeitssteigerung der Aluminiumverbunddrähte. Mit zunehmender Mischkristallverfestigung der zweiten Phase nimmt deren Neigung zur Faserbildung ab. Die Festigkeitszunahme durch die reine NaCl-Komponente beruht demnach ausschließlich auf dem Vorgang der Dispersionshärtung der Aluminiummatrix.
    Additional Material: 6 Ill.
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  • 68
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 69
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A86 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 70
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 232-232 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 71
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 72
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 247-251 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: A method for the selection of tribotechnical materials based on a system analysis of friction and wear processes. The tribological behaviour of materials cannot be specified by their physical, chemical and mechanical properties only. Besides these „system-independant“ properties „system-dependant“ data are important. This is demonstrated by applying the methods of systems analysis to friction and wear processes. Based on systems thicking a method for the selection of tribotechnical materials is outlined.
    Notes: Zur Charakterisierung des Reibungs- und Verschleißverhaltens von Werkstoffen reicht die Angabe von chemischen, physikalischen und mechanischen Werkstoffeigenschaften im allgemeinen nicht aus. Neben diesen „systemunabhängigen“ Eigenschaften sind vielmehr „systemspezifische“ Daten von Bedeutung, wie mit Hilfe der Systemanalyse von Reibungs- und Verschleißvorgängen gezeigt werden kann. Darauf aufbauend wird eine Methodik zur Auswahl von tribotechnischen Werkstoffen vorgestellt.
    Additional Material: 2 Ill.
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  • 73
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 266-267 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 74
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 268-268 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 75
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    Materialwissenschaft und Werkstofftechnik 7 (1976) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 76
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. A94 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 77
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 279-292 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Allowable limits for loads under heads of fasteners out of stainless austenitic chromium nickel steels. Safety and load carrying capacity of fastened joints are determined through the strength of the fasteners, the pressure under the head and nuts which can be endured without plastic deformations and the variation of the actual preload. The strength of screws of stainless steels are known with its variations since long time. The allowable pressure under the head and nut of fasteners for the various austenitic chromium steels in the solution annealed and cold formed condition are not known so far. The result of such investigations for the important austenitic chromium steels are published herewith. The now known loadability limits must be recognized. After loading above these limits a recreational effect was observed for which interpretations and explanations still have to be found.
    Notes: Sicherheit und Belastbarkeit von Schraubenverbindungen werden durch die Festigkeit der Schrauben, die ohne plastische Verformungen ertragbaren Flächenpressungen der verspannten Teile unter Schrauben/Mutternauflagen sowie durch die Streubreite der wirksamen Vorspannung bestimmt. Die mechanischen Festigkeiten von Schrauben aus nichtrostendem Stahl sind lange bekannt. Die zulässigen Flächenpressungen austenitischer Chrom-Nickel-Stähle im lösungsgeglühten wie im kalt verformten Zustand wurden bisher nicht ermittelt. Diese Erkenntnislücke wird für die wichtigsten austenitischen Chrom-Nickel-Stähle geschlossen. Die hierdurch jetzt zahlenmäßig festgelegten Belastbarkeitsgrenzen müssen berücksichtigt werden. Nach Überschreiten der zulässigen Flächenpressung wurde ein Erholungseffekt gefunden, dessen Erklärung und Deutung noch aussteht.
    Additional Material: 9 Ill.
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  • 78
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    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 161-166 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: On the Assessment of Protective Coatings to combat Hot Gas Corrosion on Gas Turbine Blades. Turbine blades of aero-engines are normally protected from hot gas corrosion by means of aluminium diffusion coatings. The inherent negative results of these coatings - the resistance to corrosion gains with the growing thickness of the coating, but the strength generally suffers - calls for an optimum balance between resistance to hot gas corrosion and resistance to mechanical stresses for a maximally long life of the blades. Conventional criteria - chiefly that of the progress of corrosion - not being adequate for a reliable assessment of the potential gain, it is recommended that creep and fatigue tests using simultaneously superimposed corrosion be employed for evaluating protective coatings. Tests conducted at faithfully simulated service conditions on samples and blades in cast nickel material IN 100 show how increasing thickness will cause the fatigue strength and the ductility of the coating to be reduced at a more or less rapid rate. The tests suggest the conclusion that conventional coating parameters still need improving if the optimum balance between resistance to hot gas corrosion and resistance to mechanical stresses shall be gained. The still small number of tests conducted cannot provide conclusive evidence. This paper is nevertheless published in the hope that it will invite in-depth studies of the problem of high temperature protective coatings under the additional aspect of true-to-life mechanical stresses.
    Notes: Gegen Heißgaskorrosion werden Turbinenschaufeln in Flugtriebwerken üblicherweise mit Aluminium-Diffusionsschichten geschützt. Gegenläufige Wirkungen der Schichten (die Korrosionsbeständigkeit nimmt mit wachsender Dicke zu, die Festigkeit im allgemeinen ab) erfordern eine Optimierung zwischen Beständigkeit gegen Heißgaskorrosion und Widerstand gegen mechanische Beanspruchung mit dem Ziel einer möglichst langen Lebensdauer der Schaufeln. Da bisher herangezogene Kriterien (hauptsächlich des Korrosionsfortschritts) zur zuverlässigen Beurteilung des Nutzens nicht ausreichen, werden Zeitstand- und Ermüdungsversuche unter gleichzeitig überlagerter Korrosion zur Bewertung von Schutzschichten vorgeschlagen. Betriebsnah gestaltete Versuche an Proben und Schaufeln aus dem Nickelgußwerkstoff IN 100 zeigen, wie mit zunehmender Dicke Ermüdungsfestigkeit und Zähigkeit der Schicht mehr oder weniger ausgeprägt abnehmen.Die Versuche legen den Schluß nahe, daß die bisher üblichen Beschichtungsparameter noch verbessert werden müssen um den optimalen Kompromiß zwischen Beständigkeit gegen Heißgaskorrosion und Widerstand gegen mechanische Beanspruchung zu erlangen. Bei der vorerst nur geringen Zahl von Versuchen sind die Ergebnisse als nur vorläufig zu betrachten. Die trotzdem vorgenommene Veröffentlichung soll dazu anregen, das Problem der Hochtemperatur - Schutzschichten unter dem zusätzlichen Gesichtspunkt betriebsnaher mechanischer Beanspruchung vertieft zu untersuchen.
    Additional Material: 9 Ill.
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  • 79
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 167-177 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Development of materials used in gas turbine engines. Guide lines and proposal for a priority scheme. The development of materials used in gas turbine engines has the following aims: (a) the development of functioning components from new materials, (b) quantitative assessment of the behaviour of the material for a fail-save design of the engine, (c) quantitative assessment of the effect of defects in the material and (d) the securing of a constant level of quality. In order to evaluate the large number of conceivable, individual subjects for the purpose of a priority scheme, first of all 3 subject groups are differentiated and described in more detail, the differentiating feature adopted being the development stage of the candidate engines for application. (A fourth group of general subjects is only touched on). The subject groups are distinguished by the stress put, in pursuing general development targets, on such factors as higher gas temperature, lower weight, lower price, greater reliability, longer working-life and elimination of weak spots. Within each group, a priority is given according to the (simplified) formula P = T · E · D, whereby the combined factor T represents the technical progress, E the probability of success and D the individual operational urgency.A medium-term planning of materials development programmes, carried out and alloting priorities in this way, can serve as a basis not only for in-house budget planning, but also for national and international cooperation.
    Notes: Die werkstofftechnische Entwicklung im Triebwerkbau zielt auf (a) die Entwicklung funktionsfähiger Komponenten aus neuen Werkstoffen, (b) quantitative Ermittlung des Werkstoffverhaltens für die sichere Auslegung der Triebwerke, (c) die quantitative Ermittlung des Einflusses von Werkstoffehlern und (d) die Sicherstellung einer gleichbleibenden Qualität. Um die große Zahl der denkbaren Einzelthemen im Sinne einer Priorisierung bewerten zu können, werden zunächst drei Themengruppen unterschieden und näher beschrieben, wobei als unterscheidendes Merkmal der Entwicklungsstand der Triebwerke eingeführt wurde, die für eine Anwendung in Frage kommen. (Eine vierte Themengruppe mit Themen allgemeiner Art wird nur kurz gestreift). Die Themengruppen unterscheiden sich in der Gewichtung, mit der allgemeine Entwicklungsziele wie höhere Gastemperatur, niedrigeres Gewicht, geringerer Preis, größere Zuverlässigkeit, längere Lebensdauer und Schwachstellenbeseitigung verfolgt werden. Innerhalb jeder Gruppe wird eine Priorisierung nach der (vereinfachten) Formel P = T · E · D durchgeführt, wobei die zusammengesetzte Größe T den technischen Fortschritt, E die Erfolgswahrscheinlichkeit und D die individuelle betriebliche Dringlichkeit repräsentieren.Eine auf diese Weise durchgeführte und priorisierte Mittelfristplanung von Werkstoffentwicklungsprogrammen kann als Basis sowohl für betriebsinterne Budgetplanung als auch für nationale und internationale Kooperation dienen.
    Additional Material: 12 Ill.
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  • 80
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 181-189 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Optimizing the Machinability of Free Cutting Steel. Competitive machining requires steels which guarantee a low tool wear, favourable chip form and a high grade surface finish, even unter extreme cutting conditions. Free cutting steels containing special alloying elements which improve the machinability, meet these requirements to a high degree. Machinability depends highly on the chip formation process, in particular size, form and the influence of the built-up edges (BUE).BUE's are formed, depending on the chemical composition, at cutting speeds of v = 100 m/min and more, and have a decisive influence on the tool wear. The influence of the alloying elements Carbon, Sulfur, Manganese, Phosphorus, Nitrogen, Silicon, Aluminium, Lead, Bismuth and Tellurium on the tool life has been studied under working conditions almost similar to praxis.Knowledge of the effect of single combinations of alloying elements allows optimal adaptation of the free machining properties of free-cutting steels to the set requirements.
    Notes: Die wirtschaftliche Fertigung spanend bearbeiteter Werkstücke erfordert Stähle, die selbst bei extremen Schnittbedingungen geringen Werkzeugverschleiß, günstige Spanformen und hohe Oberflächengüten gewährleisten. Diese Anforderungen werden weitgehend von den Automatenstählen erfüllt, denen besondere Legierungselemente zur Verbesserung der Zerspanbarkeit zugegeben werden. Die Zerspaneigenschaften sind wesentlich von den Vorgängen bei der Spanentstehung abhängig, insbesondere von der Größe, Form und Wirkungsweise der Aufbauschneiden. Aufbauschneiden entstehen bei Automatenstählen je nach chemischer Zusammensetzung bis zu Schnittgeschwindigkeiten von v = 100 m/min und darüber und beeinflussen entscheidend den Werkzeugverschleiß. Einfluß und Wirkungsweise der Legierungselemente Kohlenstoff, Schwefel, Mangan, Phosphor, Stickstoff, Silizium, Aluminium, Blei, Wismut und Tellur auf die Werkzeugstandzeit werden unter praxisnahen Zerspanbedingungen untersucht. Die Kenntnis der Wirkung einzelner Legierungskombinationen erlaubt es, Automatenstähle in ihren Zerspaneigenschaften optimal den gestellten Anforderungen anzupassen.
    Additional Material: 14 Ill.
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  • 81
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 193-194 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 82
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 190-192 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Sintering of iron-manganese with tin additions. Small tin additions strongly influence the sintering behaviour of iron-manganese powder compacts. Dilatometric, metallographic and microprobe investigations enable conclusions about the sinter processes. At low temperatures the molten tin reacts with the manganese particles to form various intermetallic compounds. Above 900°C, melting of these intermetallics causes swelling of the compacts and fast homogenization. Therefore at the relatively low sintering temperatures of 1050 to 1100°C mechanical properties are achieved in iron-manganese-tin compacts which are comparable with the properties of iron-manganese sintered at 1300°C.
    Notes: Das Sinterverhalten von Eisen-Mangan-Pulverpreßlingen wird durch Beimischung kleiner Zinnmengen stark beeinflußt. Dilatometrische, metallographische und Mikrosondenuntersuchungen gestatten Aussagen über die Sintervorgänge. Nach dem Aufschmelzen reagiert das flüssige Zinn bevorzugt mit den Manganpulverteilchen und bildet verschiedene intermetallische Verbindungen. Oberhalb von 900°C schmelzen diese Verbindungen. Dies verursacht Schwellen der Pulverpreßlinge und beschleunigt die Homogenisierung. Eisen-Mangan-Zinn-Preßlinge erreichen daher schon durch Sinterung bei 1050 bis 1100°C mechanische Eigenschaftswerte, wie sie Eisen-Man-gan-Mischungen erst nach Sinterung bei etwa 1300°C aufweisen.
    Additional Material: 6 Ill.
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  • 83
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 84
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    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 195-195 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 85
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 86
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 87
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 195-195 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 88
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 89
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 196-196 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 90
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 368-376 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Tribological Processes of the Ball Bearing Steel 100 Cr 6. Tribomechanical and tribochemical processes of the ball bearing steel 100 Cr 6 were investigated under the influence of ultra high vacuum and different gases by the pin/ring method. The conditions for adhesive wear indicated by prow formation were optimal in ultra high vacuum. Pressures of oxygen, nitrogen and air greater than 10-6 Pa increase the lubrication by formation of thin films, measured by ellipsometry. Increasing nitrogen pressure produces a surface hardening, which can be observed by nitrided wear particles. The presence of pure oxygen creates permanently oxide films with a thickness of 10 nm. This causes abrasive wear.
    Notes: Tribomechanische und -chemische Vorgänge an dem Kugellagerstahl 100 Cr 6 wurden nach der Stift-Ring-Methode im Ultrahochvakuum und unter verschiedenen gasförmigen Medien untersucht. Im Ultrahochvakuum werden optimale Bedingungen für Adhäsionsverschleiß mit ausgeprägter Keilbildung beobachtet. Sauerstoff, Stickstoff und Luft führen bereits bei Drucken oberhalb von 10-6 Pa zu Gleitverbesserung bei teilweise geringen, ellipsometrisch bestimmten Schichtdicken. Bei steigendem Stickstoffdruck resultiert eine Oberflächenhärtung, wobei an den Verschleißpartikeln eine Aufstickung nachzuweisen ist. Reiner Sauerstoff führt zu Schichtverschleiß bei sich ständig neu bildenden Oxidationsschichten von ca. 10 nm Dicke.
    Additional Material: 13 Ill.
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  • 91
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 92
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 93
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 197-197 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 94
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Influence of oscillating normal forces on friction and wear. The load carrying capacity and the course of friction und wear can be influenced by superposition of a dynamic load to a statically applied load. The influence of frequency and amplitude on load carrying capacity wear limit and wear rate is demonstrated.
    Notes: Die Belastbarkeit und der Verlauf von Reibung und Verschleiß sind durch dynamische Zusatzbelastungen beeinflußbar. Der Einfluß von Frequenz und Amplitude auf die Belastbarkeit, Verschleißbeginn und Verschleißverlauf wird dargestellt.
    Additional Material: 3 Ill.
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  • 95
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 256-261 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Nickel-Molybdenum Sintered Steels for High Duty Parts. Fe-Ni-Mo steels without additions and with 0,45% P resp. 0,5% C added were sintered at 1150°C resp. 1250°C for 1 h in H2.2% Ni and 1,5% Mo resp. 4% Ni and 3% Mo were added as alloying elements. The strength of the sintered Fe-Ni-Mo alloys without additional elements did not exceed remarkably that of the sintered steels used up to now. Fe-Ni-Mo steels with 4% Ni and 3% Mo sintered at 1250°C with an addition of 0,45% P resp. 0,5% C have a tensile strength of 740 N/mm2 resp; 830 N/mm2. However the impact toughness of the alloy with P is remarkably higher than that of the alloy with C. The C-content determines mainly the strength properties of the alloys with C and influences the diffusion of the Mo too. The influence of the Ni and Mo on the properties of the alloys with P is more obvious. Alloys with 4% Ni and 3% Mo containing 0,45% P have good static and dynamic strength and therefore are capable for high duty parts.
    Notes: Fe-Ni-Mo-Sinterstähle wurden mit und ohne Zusatz von 0,45% P bzw. 0,5% C bei 1150°C bzw. 1250°C gesintert. Die Ni- und Mo-Gehalte betrugen 2% und 1,5% bzw. 4% und 3%. Während die Festigkeitseigenschaften der Fe-Ni-Mo-Legierungen ohne Zusatz die der heute meist verwendeten Sinterstähle nicht merklich übersteigen, liegen die der Fe-Ni-Mo-Sinterlegierungen mit P- bzw. C-Zusatz deutlich höher. Die Legierungen mit 4% Ni, 3% Mo und 0,45% P bzw. 0,5% C, gesintert bei 1250°C, haben σB-Werte von 740 N/mm2 bzw. von 830 N/mm2. Die P-haltige Legierung hat jedoch eine wesentlich höhere Schlagzähigkeit als die C-haltige.Der Kohlenstoff bestimmt im wesentlichen die Eigenschaften der C-haltigen Legierung und beeinflußt auch die Mo-Diffusion. Bei den P-haltigen Legierungen ist der Einfluß der Legierungselemente Ni und Mo auf die Festigkeitseigenschaften viel ausgeprägter.Die P-haltige Legierung mit 4% Ni und 3% Mo hat gute statische und dynamische Festigkeitseigenschaften. Sie eignet sich deshalb gut für hochbeanspruchte Sinterteile.
    Additional Material: 14 Ill.
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  • 96
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    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 268-268 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 97
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 298-299 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: An Approach to a Ductility Criterion. The capacity of materials for plastic deformation notably helps prevent component failures. As yet, no criterion exists for the ductility requirement to be imposed. A theorem is here proposed to assist in the determination of the ductility requirement by assessing five load characteristics.These characteristics are: utilization of the material, unsafety of the load assumption, energy absorption requirement, complexity of component configuration, and safety requirement.
    Notes: Das plastische Verformungsvermögen der Werkstoffe trägt entscheidend zur Verhütung von Bauteilversagen bei. Für die zu fordernde Zähigkeit existiert bisher kein Kriterium. Mit einem vorgeschlagenen Leitsatz läßt sich die zu fordernde Zähigkeit durch Bewertung von fünf Beanspruchungsmerkmalen bestimmen.Diese Merkmale sind: Ausnutzungsgrad des Werkstoffs, Unsicherheit in der Lastannahme, geforderte Energieaufnahme, Kompliziertheit der Bauteilgestalt und Sicherheitsanforderung.
    Additional Material: 1 Ill.
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  • 98
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 99
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 100
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 7 (1976), S. 325-328 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Dilatometric measurements may give a valuable contribution to the treatment of problems in composite materials, which are related to: athermal expansion coefficient: -internal stresses due to differences in the thermal expansion behaviour to the phases-anisotropy of the thermal expansion coefficient in unidirectional or bulk composits-adjustment of the overall thermal expansion coefficient through modification of alloy compositionbphase transformation: -temperature and amount of volume change of the suddenly occuring transformation of one phase influence the internal stressesThe potential of dilatometric measurements when dealing with problems of mechanical compatibility in composite materials is illustrated by several examples taken from the literature and from own work.
    Notes: Die dilatometrische Meßmethode liefert Beiträge zu folgenden Problemen der Verbundwerkstoffe: aAusdehnungskoeffizient -Unterschiedliche Ausdehnungskoeffizienten einzelner Komponenten von Verbundwerkstoffen führen zu Eigenspannungen.-In gerichteten und geschichteten Verbundwerkstoffen sind anisotrope Ausdehnungskoeffizienten zu erwarten.-Verbundwerkstoffe können auch unter dem Gesichtspunkt der gezielten Beeinflussung des Ausdehnungskoeffizienten hergestellt werden. Bei Aluminium können z. B. durch Einlagern von Glas- oder Sitalfasern Werte von 〈 10.10-6 (1/°C) erzielt werden (1).bUmwandlungen Die Umwandlungstemperatur und das Ausmaß der plötzlichen Längenänderung beeinflussen die entstehenden Eigenspannungen.
    Additional Material: 7 Ill.
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