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  • 2000-2004  (25)
  • 1930-1934  (1.172)
  • 1925-1929  (808)
  • 1860-1869
  • Cell & Developmental Biology  (1.980)
  • Ultrastructure
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  • 1
    Digitale Medien
    Digitale Medien
    The need for speed. II. Myelin in calanoid copepods (2000)
    Springer
    Journal of comparative physiology 186 (2000), S. 347-357 
    Details
    ISSN: 1432-1351
    Schlagwort(e): Key words Crustacean ; Sensorimotor ; Ultrastructure ; Multilamellar sheath ; Myelinated axons
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Speed of nerve impulse conduction is greatly increased by myelin, a multi-layered membranous sheath surrounding axons. Myelinated axons are ubiquitous among the vertebrates, but relatively rare among invertebrates. Electron microscopy of calanoid copepods using rapid cryofixation techniques revealed the widespread presence of myelinated axons. Myelin sheaths of up to 60 layers were found around both sensory and motor axons of the first antenna and interneurons of the ventral nerve cord. Except at nodes, individual lamellae appeared to be continuous and circular, without seams, as opposed to the spiral structure of vertebrate and annelid myelin. The highly organized myelin was characterized by the complete exclusion of cytoplasm from the intracellular spaces of the cell generating it. In regions of compaction, extracytoplasmic space was also eliminated. Focal or fenestration nodes, rather than circumferential ones, were locally common. Myelin lamellae terminated in stepwise fashion at these nodes, appearing to fuse with the axolemma or adjacent myelin lamellae. As with vertebrate myelin, copepod sheaths are designed to minimize both resistive and capacitive current flow through the internodal membrane, greatly speeding nerve impulse conduction. Copepod myelin differs from that of any other group described, while sharing features of every group.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s003590050435
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  • 2
    Digitale Medien
    Digitale Medien
    Immunohistochemical localization of mitogen-activated protein kinase (MAPK) family and morphological changes in rat heart after ischemia-reperfusion injury (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 74-81 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Mitogen-activated protein kinase (MAPK) ; Ischemia reperfusion injury ; Heart ; Ultrastructure ; Immunohistochemistry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The mitogen-activated protein kinase (MAPK) family is considered to be activated by stress, but the role of the MAPK family is still unknown in cardiac pathology. In the present study, not only the localization of MAPKs such as the extracellular responsive kinase (ERK), c-jun N-terminal kinase (JNK), and p38 MAPK (p38), but also ultrastructural changes were investigated in the ischemia-reperfusion model of Wistar rats. At 5, 10, 30, 60, and 180 min reperfusion after 30 min ischemia by occluding the coronary artery, the expression of these MAPKs was increased in blood vessels and cardiomyocytes by Western blotting and immunohistochemical methods. In addition, after ischemia reperfusion, various ultrastructural changes such as decreased glycogen granules, mitochondrial swelling, and myolysis were observed in the blood vessels and cardiomyocytes. These results suggest that protein kinases may regulate numerous biological processes, including the regulation of contraction and ion transport.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950070005
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  • 3
    Digitale Medien
    Digitale Medien
    An immunohistochemical and ultrastructural study of a follicle-stimulating hormone-secreting gonadotroph adenoma occurring in a 10-year-old girl (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 25-31 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Gonadotroph adenoma ; FSH ; Childhood ; Ultrastructure ; Immunohistochemistry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Female gonadotroph adenomas with endocrinological symptoms are uncommon. Six cases of such adenomas have been reported in the literature: two were girls who presented with precocious puberty and four were premenopausal women with accompanying multiple ovarian cysts. We describe here a 10-year-old Japanese girl with a gonadotroph macroadenoma and present detailed morphological findings of the tumor. The patient's chief complaints were nausea, abdominal distention, and abdominal pain. Abdominopelvic ultrasonography and magnetic resonance imaging (MRI) revealed bilateral multiple ovarian cysts. Endocrinological assays showed elevated serum follicle-stimulating hormone (FSH) (33.7 mIU/ml) and estradiol (3840 pg/ml). MRI of the head showed a large pituitary tumor. Two transsphenoidal operations and subsequent radiation therapy were performed. Immunohistochemically, more than half the tumor cells were positive for anti-FSH-β monoclonal antibody. Ultrastructurally, the tumor cells exhibited a fairly uniform picture of rounded cells. Their nuclei were slightly irregular and contained heterochromatin, and their cytoplasm contained many round, dense core granules, measuring 140–260 nm in diameter, together with well-developed organelles. An in vitro study showed that the tumor cells in primary culture produced FSH (1089.0 mIU/ml). To our knowledge, this is the first immunohistochemical and ultrastructural study of an FSH-secreting gonadotroph adenoma occurring in childhood.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950000004
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  • 4
    Digitale Medien
    Digitale Medien
    Ultrastructural evaluation of apoptosis induced by Helicobacter pylori infection in human gastric mucosa: novel remarks on lamina propria mucosae (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 82-88 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Apoptosis ; Helicobacter pylori ; Fibroblasts ; Smooth muscle cells ; Ultrastructure ; Gastroduodenal ulcer
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract It has been considered that Helicobacter pylori (H. pylori) infection is a major cause of human gastritis and gastroduodenal ulcers (G-DU). Many investigations of the relationship between H. pylori and apoptosis have been reported recently. However, these studies focused mostly on epithelium, using the TUNEL method. In the present study, we evaluated by electron microscopy the occurrence of apoptosis in the mesenchymal cells of lamina propria mucosae infected with H. pylori. Gastric biopsy specimens from 37 H. pylori-infected G-DU patients and 8 noninfected volunteers were examined with both light and electron microscopy and analyzed by the TUNEL method. The TUNEL method showed no significant difference between H. pylori-infected and noninfected cases. In contrast, electron microscopy revealed significant numbers of apototic fibroblasts and smooth muscle cells in H. pylori-infected lamina propria mucosae, with a diminished number of collagen fibers in surrounding areas. These areas showed edematous changes histopathologically. These results indicated that H. pylori infection induces apoptosis of fibroblasts and smooth muscle cells in lamina propria, with decrease in the numbers of collagen fibers, suggesting that these alterations may be affected by exaggerate acid secretion, decrease mucus protecting factors, and result in ulcer formation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950070006
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  • 5
    Digitale Medien
    Digitale Medien
    Ciliogenesis and ciliary abnormalities (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 109-114 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Ciliogenesis ; Ciliated cell ; Abnormal cilia ; Basal body ; Ultrastructure ; Human
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Cilia are motile processes extending from the basal bodies, playing important roles in the mucociliary clearance in the respiratory tract and the transport of the ovum from the ovary to the uterus in mammals. Ciliogenesis is divided into four stages: (1) duplication of centrioles; (2) migration of centrioles to the apical cell surface to become basal bodies; (3) elongation of cilia containing the axoneme; and (4) formation of accessory structures of basal bodies. The orderly course of ciliogenesis appears to be disturbed by various internal and external factors and, as a result, various unusual forms of the ciliary apparatus develop in the cell. Inhibition of basal body migration results in development of intracytoplasmic axonemes, cilia within periciliary sheaths, and intracellular ciliated cysts. Swollen cilia and the bulging type of compound cilia are formed during ciliary budding and elongation. This review also discusses the origin, composition, and function of the centriolar precursor structures.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950000009
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  • 6
    Digitale Medien
    Digitale Medien
    Abnormal elastic system fibers in fibrotic human liver (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 135-142 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Elastic system fiber ; Ultrastructure ; Fibrotic human liver ; Oxytalan fiber ; Elaunin fiber
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The network of elastic system fibers in human fibrotic liver was investigated by histological methods, immunohistochemical staining, and electron microscopy. Type III collagen was seen not only in regions of portal fibrosis but also in the sinusoidal wall. However, elastic system fibers were not found in the Disse space of the sinusoidal wall. Elastic system fibers including oxytalan, elaunin, and elastic fibers were found successively in the course of elastogenesis. A few normal oxytalan fibers and abnormal oxytalan fibers were observed in the periportal tracts. Few normal elaunin and abnormal elaunin fibers were observed in regions of portal fibrosis but not in the surrounding margin. Elastic fibers, only in scarce amounts, were observed around the portal veins in the case of chronic active hepatitis but not in acute hepatitis. Abnormal oxytalan fibers were seen as a bundle of wavelike microfibrils and had an irregular arrangement. Abnormal elaunin fibers were not associated with bundles of microfibrils. Abnormal elaunin fibers in large amounts were found interspersed with spiraled collagen, which most likely indicates that the oxytalan fibers degenerated in the course of elastogenesis. Thus, in a fibrotic liver it is possible that synthesis of normal elaunin and elastic fibers does not occur or that the quantity of such fibers synthesized may be small because of the effect of the degenerated oxytalan fibers. As a characteristic of liver fibrosis, the composition of abnormal elastic system fibers and spiraled collagen differs from that in other fibrotic organs.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950000013
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  • 7
    Digitale Medien
    Digitale Medien
    Adenoid basal carcinoma of the uterine cervix: a case report with ultrastructural findings (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 241-245 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Adenoid basal carcinoma ; Uterine cervix ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Adenoid basal carcinoma of the uterine cervix is a rare tumor with a favorable prognosis. A case of adenoid basal carcinoma (ABC) of the uterine cervix was studied using light and electron microscopy. The patient was a 74-year-old Japanese woman who had undergone hysterectomy due to cervical intraepithelial neoplasia 3. Incidentally, ABC was found in the resected uterus. The tumor cells made small nests and infiltrated the cervical portion of the uterus. In the nests, glands, cribriform patterns with glandlike structures, and squamous differentiation were seen. Immunohistochemically, the glandlike structures were positive for laminin and type IV collagen. Ultrastructurally, the tumor cells had irregular nuclei, scanty cytoplasm, and cribriform patterns in which glandlike structures were covered with basal lamina. No myoepithelial differentiation of the tumor cells was seen. These findings suggest a similarity between adenoid basal carcinomas and adenoid cystic carcinomas. Furthermore, both tumors are considered to originate in the reserve cells of the uterine cervix. Because their outcomes are different, they should be distinguished from each other.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950000024
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  • 8
    Digitale Medien
    Digitale Medien
    Variation among giant rice bodies: report of four cases and their clinicopathological features (2000)
    Springer
    Skeletal radiology 29 (2000), S. 525-529 
    Details
    ISSN: 1432-2161
    Schlagwort(e): Key words Giant rice body ; Ultrastructure ; Immunohistochemistry ; Histogenesis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Objective: To report four cases of rice bodies (RBs) showing remarkable size variations and discuss their pathogenesis. Design and patients: Based on analysis of the clinical data, we speculate on the pathogenesis of RBs using immunohistochemical and ultrastructural methods. The patients comprised three men and one woman, three with RBs in the subacromial bursae and one in the wrist synovial sheath, aged 28 (woman), 44, 50 and 81 (wrist) years, respectively. Results: There were no particular differences in clinical data among the patients. T2-weighted MR imaging was very useful for diagnosis of the RBs, allowing their clear delineation from the bursal fluid. The RBs consisted of a layered protein- aceous substance with vague targetoid cut surfaces. Much fibrin and a lesser amount of collagen fibers were recognized together with various mononuclear cells, which were few in number and predominantly T cells. The bursae and synovial sheath had multiple fibrinoid spheroids at the luminal surface. Conclusion: Fibrinoid nodular deposits probably became detached, forming the nuclei of RBs and growing to a giant RB 65 mm in diameter.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002560000258
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  • 9
    Digitale Medien
    Digitale Medien
    Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis) (2000)
    Springer
    Virchows Archiv 436 (2000), S. 257-270 
    Details
    ISSN: 1432-2307
    Schlagwort(e): Key words Arteriogenesis ; Collateral vessels ; Ultrastructure ; Cell adhesion molecules
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Previous studies in the canine heart had shown that the growth of collateral arteries occurs via proliferative enlargement of pre-existing arteriolar connections (arteriogenesis). In the present study, we investigated the ultrastructure and molecular histology of growing and remodeling collateral arteries that develop after femoral artery occlusion in rabbits as a function of time from 2 h to 240 days after occlusion. Pre-existent arteriolar collaterals had a diameter of about 50 µm. They consisted of one to two layers of smooth muscle cells (SMCs) and were morphologically indistinguishable from normal arterioles. The stages of arteriogenesis consisted of arteriolar thinning, followed by transformation of SMCs from the contractile- into the proliferative- and synthetic phenotype. Endothelial cells (ECs) and SMCs proliferated, and SMCs migrated and formed a neo-intima. Intercellular adhesion molecule (ICAM-1) and vascular cell adhesion molecule (VCAM-1) showed early upregulation in ECs, which was accompanied by accumulation of blood-derived macrophages. Mitosis of ECs and SMCs started about 24 h after occlusion, whereas adhesion molecule expression and monocyte adhesion occurred as early as 12 h after occlusion, suggesting a role of monocytes in vascular cell proliferation. Treatment of rabbits with the pro-inflammatory cytokine MCP-1 increased monocyte adhesion and accelerated vascular remodeling. In vitro shear-stress experiments in cultured ECs revealed an increased phosphorylation of the focal contacts after 30 min and induction of ICAM-1 and VCAM-1 expression between 2 h and 6 h after shear onset, suggesting that shear stress may be the initiating event. We conclude that the process of arteriogenesis, which leads to the positive remodeling of an arteriole into an artery up to 12 times its original size, can be modified by modulators of inflammation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004280050039
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  • 10
    Digitale Medien
    Digitale Medien
    Ganglioglioma with a tanycytic ependymoma as the glial component (2000)
    Springer
    Acta neuropathologica 99 (2000), S. 310-316 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words Ganglioglioma ; Ependymoma (tanycytic variant) ; Neurofibrillary tangle ; Immunohistochemistry ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We studied a cystic ganglioglioma (GG) located in the right frontal lobe of the brain. Interestingly, the fibrillary spindle glial cells were often arranged in a fascicular pattern, and the generally uniform, round-to-oval delicate nuclei appeared to resemble those of ependymoma; and the neoplastic neurons often contained neurofibrillary tangles (NFTs). The glial component was positive for glial fibrillary acidic protein and occasionally contained granular or microvesicular structures positive for epithelial membrane antigen. Ultrastructural investigation revealed that the glial cells were ependymal in nature; intracytoplasmic lumina and intercellular microrosettes lined with cilia and microvilli, as well as long zonulae adherentes, were evident. In addition, chromogranin A-positive granular staining, neurosecretory-granule-like structures, and parallel arrays of microtubules were sometimes associated with the blood vessels. We considered the present case to be an unusual example of GG with an ependymoma, more precisely a tanycytic ependymoma, as the glial component; to our knowledge, the existence of ependymoma as the main glial component of this particular tumor has not been described before. The occurrence of NFTs, which has been reported in several cases of GG, was an additional, unusual feature.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/PL00007443
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  • 11
    Digitale Medien
    Digitale Medien
    Eosinophilic inclusions in ependymoma represent microlumina: a light and electron microscopic study (2000)
    Springer
    Acta neuropathologica 99 (2000), S. 214-218 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words Eosinophilic inclusion body ; Inclusion ¶body ; Ependymoma ; Microlumina ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A study was undertaken to determine the pathological significance of previously unrecognized intracytoplasmic eosinophilic inclusions (IEIs) in ependymoma. The study group consisted of 58 ependymomas, all of which were pathologically characterized and graded according to the 1993 WHO classification. Electron microscopic studies were performed in 16 cases. The study showed that 33 (57%) ependymomas had IEIs and that in 8 cases these were abundant. Round and eosinophilic, their sizes varied from 10 μm to a tiny dot. Similar eosinophilic bodies were also observed between tumor cells. The inclusions were weakly PAS positive. On immunostains, IEIs were frequently positive for glial fibrillary acidic protein, less often for S-100 protein, and for epithelial membrane protein and CAM 5.2. They were negative for AE1/AE3, carcinoembryonic antigen and Ber-EP4. Ultrastructurally, IEIs represented intracytoplasmic lumens containing microvilli and cilia. These microlumina also frequently contained granulo-tubular materials. With reference to tumor subtypes, IEIs occurred most frequently in ordinary and clear cell ependymomas. IEIs were also present in 4 of 6 anaplastic ependymomas studied. In conclusion, IEIs represent microlumina and occur in more than a half of ependymomas including malignant examples. Their finding is a helpful diagnostic feature of ependymoma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/PL00007427
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  • 12
    Digitale Medien
    Digitale Medien
    Ultrastructure of the normal adult human female prostate gland (Skene’s gland) (2000)
    Springer
    Anatomy and embryology 201 (2000), S. 51-61 
    Details
    ISSN: 1432-0568
    Schlagwort(e): Key words Female prostate (Skene gland) ; Ultrastructure ; Secretory (luminal) cells ; Basal (reserve) cells ; Intermediary cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  The predominant cells of female prostatic glands lining their lumen were found to be tall cylindrical secretory cells with short stubby microvilli, protuberances of the apical cytoplasm, and with bleb formation. Abundant secretory vacuoles and granules, rough endoplasmic reticulum, developed Golgi complexes and numerous mitochondria are characteristic of their active secretory configuration with apocrine (apical blebs) and merocrine (secretory vacuoles and granules) type of secretion. Basal (reserve) cells were seen to be located between the secretory (luminal) cells and the basement membrane. Their ground cytoplasm is dense with rough endoplasmic reticulum and mitochondria. Their nuclei, unlike those of secretory cells, possess more peripheral condensed chromatin, denser dispersed chromatin and sporadic nucleoli. Besides the two basic types of mature prostatic cells intermediary cells were also seen, located between the basal and secretory cells or in their close vicinity. Their cytoplasm exhibits numerous profiles of rough endoplasmic reticulum and free ribosomes. Secretory vacuoles and granules were mostly practically absent (type 1 intermediary cells) so that they resembled basal (reserve) cells. In some of them, however, as in secretory cells, such secretory elements do gradually appear (type 2 intermediary cells). The finding of intermediary cells in the lining of prostatic glands supports the role of basal (reserve) cells in the renewal of cells in glands of the female prostate. The first ultrastructural analysis of the normal female prostate performed by transmission electron microscopy showed that, as in the postpubertal male, the prostatic glands in the adult female display mature secretory and basal cells. The results of the presented study further corroborate the contemporary concept of the female prostate as a functional genitourinary organ.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/
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  • 13
    Digitale Medien
    Digitale Medien
    Microglial cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation (2000)
    Springer
    Acta neuropathologica 100 (2000), S. 356-364 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words Alzheimer disease ; Fibrillar amyloid-β ; Astrocytes ; Microglial cell ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Ultrastructural three-dimensional reconstruction of human classical plaques in different stages of development shows that microglial cells are the major factor driving plaque formation by fibrillar amyloid-β (Aβ) deposition. The amount of fibrillar Aβ released by microglial cells and the area of direct contact between amyloid and neuron determine the extent of dystrophic changes in neuronal processes and synapses. The volume of hypertrophic astrocytic processes separating fibrillar amyloid from neuron is a measure of the protective activation of astrocytes. On the bases of the volume of amyloid star, microglial cells, dystrophic neurites, and hypertrophic astrocytic processes, and spatial relationships between plaque components, three stages in classical plaque development have been distinguished: early, mature, and late. In early plaque, the leading pathology is fibrillar Aβ deposition by microglial cells with amyloid star formation. The mature plaque is characterized by a balance between amyloid production, neuronal dystrophy, and astrocyte hypertrophy. In late classical plaque, microglial cells retract and expose neuropil on direct contact with amyloid star, enhancing both dystrophic changes in neurons and hypertrophic changes in astrocytes. In late plaques, activation of astrocytes predominates. They degrade amyloid star and peripheral amyloid wisps. The effect of these changes is classical plaque degradation to fibrillar primitive and finally to nonfibrillar, diffuse-like plaques.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004010000199
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  • 14
    Digitale Medien
    Digitale Medien
    GM1-gangliosidosis in a cross-bred dog confirmed by detection of GM1-ganglioside using electrospray ionisation-tandem mass spectrometry (2000)
    Springer
    Acta neuropathologica 100 (2000), S. 409-414 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words GM1-gangliosidosis ; Ultrastructure ; Electrospray ionisation tandem mass spectrometry ; Diagnosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The post-mortem diagnosis of lysosomal storage diseases can be confounded by the unavailability of suitable material. Here we report the diagnosis of GM1-gangliosidosis in a cross-bred dog, from which only formalin-fixed brain was available, by a combination of electron microscopy and the detection of elevated levels of GM1-ganglioside within the tissue using the novel technique of electrospray ionisation tandem mass spectrometry. Electron microscopic examination of ultrathin sections of resin-embedded tissue revealed cytoplasmic inclusions (membranous cytoplasmic and zebra bodies) in brain stem and cerebellar neurons that were characteristic of a gangliosidosis. Glycolipids were extracted from the fixed tissue and analysed by tandem mass spectrometry. Two major ions were detected, which corresponded to GM1 (d18:1–C18:0) and GM1 (d20:1–C18:0). Their identity was confirmed by comparison of their fragmentation patterns with those of authentic standards. The concentration of GM1 was approximately sixfold higher on a wet weight basis than in the brain of a normal control dog, confirming the diagnosis of GM1-gangliosidosis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004010000187
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  • 15
    Digitale Medien
    Digitale Medien
    Light and electron microscopic examination of endothelial cells from bovine retinal vessels in long-term cultures (2000)
    Springer
    Virchows Archiv 436 (2000), S. 249-256 
    Details
    ISSN: 1432-2307
    Schlagwort(e): Key words Endothelial cells ; Cell culture ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  The aim of the present work was to examine and compare the ultrastructure of bovine retinal endothelial cells (BRECs) in vitro during several passages in a medium selective for endothelial cells. The identity of the endothelial cells was confirmed immunohistochemically, up to the tenth passage. Changes in their ultrastructure in comparison to endothelial cells in vivo occurred at the onset of culturing and not progressively with repeated passages. The cultured BRECs show high metabolic activity in all passages. While retaining their identity as endothelial cells, they modify their lipid metabolism, so that lipids are stored. This change in lipid metabolism was induced by the medium.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004280050038
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  • 16
    Digitale Medien
    Digitale Medien
    The ultrastructure of photoreceptor cells in the pineal organ of the blind cave salamander, Proteus anguinus (Amphibia, Urodela) (2000)
    Springer
    Pflügers Archiv 439 (2000), S. r175 
    Details
    ISSN: 1432-2013
    Schlagwort(e): Key words Pineal organ ; Photoreceptor cells ; Ultrastructure ; Proteus anguinus ; Regressive evolution
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We studied ultrastructure of the photoreceptor cells in the pineal organ of blind, depigmented, neotenic cave salamander, Proteus anguinus. Unlike in epigean vertebrates the outer segments of most photoreceptor cells consists of concentrically arranged lamellae, however; in few cells, the outer segments contain 7-9 plasma membrane disks. In both types of photoreceptor cells the outer segments enclose lumps of vesicles of different sizes. The photoreceptor cells of Proteus anguinus are similar to those in other cavernicolous fish species.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004240000136
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  • 17
    Digitale Medien
    Digitale Medien
    Atypical morphological characteristics and surface antigen expression of Burkholderia pseudomallei in naturally infected human synovial tissues (2000)
    Springer
    Modern rheumatology 10 (2000), S. 129-136 
    Details
    ISSN: 1439-7609
    Schlagwort(e): Key words Septic arthritis ; Surface antigens ; Ultrastructure ; Burkholderia pseudomallei ; IEM
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Burkholderia pseudomallei is the causative agent of melioidosis, a disease that frequently runs a protracted course and is very difficult to eradicate. The mechanisms that this organism uses to escape from host defense mechanisms and antibiotics are not well understood. The aim of the study was to compare the morphological characteristics and surface antigen expression of B. pseudomallei in naturally infected human synovial tissues with the characteristics of bacteria grown in culture media. Immunoelectron microscopic study was performed in four synovial biopsies taken from four B. pseudomallei septic arthritis patients. Colonies of pathogenic B. pseudomallei collected from culture media were used as positive controls. Polyclonal antibody to whole cell B. pseudomallei was used as a primary antibody. Complete bacteria-like particles were demonstrated both extracellularly and intracellularly in all four synovial specimens. The intracytoplasmic location of B. pseudomallei and mononuclear phagosome containing microcolony-like structures were demonstrated. B. pseudomallei found in the synovial membrane samples were mostly atypical, with fewer cytoplasmic electron lucent granules. Immunogold staining of bacterial surface antigens was weaker than staining of positive controls. We demonstrated atypical forms of B. pseudomallei and evidence for suppression of its surface antigens in naturally infected human synovial tissues. This adaptation may help bacteria to survive despite host immune surveillance and treatment with antibiotics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s101650070019
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  • 18
    Digitale Medien
    Digitale Medien
    Glomus claroideum forms an arbuscular mycorrhiza-like symbiosis with the hornwort Anthoceros punctatus (2000)
    Springer
    Mycorrhiza 10 (2000), S. 15-21 
    Details
    ISSN: 1432-1890
    Schlagwort(e): Anthoceros punctatus ; Arbuscular mycorrhiza ; Bryophytes ; Glomus ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Glomus claroideum (Schenck & Smith emend. Walker & Vestberg) were investigated for ability to form arbuscular mycorrhiza-like symbioses with the hornwort Anthoceros punctatus (L.). Spores were transferred to a cellulose acetate filter on water agar and a small portion of an Anthoceros thallus was placed directly upon the spores. Light-microscope observations 20 days after inoculation revealed branched hyphae growing within the thallus. After 45 days, arbuscules and vesicles were studied by light- and electron-microscopy. After 60 days in water agar culture, the colonised Anthoceros thalli were transferred to a low-nutrient medium agar. Hyphae spread in the agar and newly formed spores were observed 5 weeks after the transfer. After 4 months, about 1000 spores were formed in each Petri dish. This is the first report of an experimentally established arbuscular mycorrhiza-like symbiosis between an identified fungus belonging to the Glomales and a bryophyte.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s005720050282
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  • 19
    Digitale Medien
    Digitale Medien
    Chronic effects of streptozotocin-induced diabetes on the ultrastructure of rat ventricular and papillary muscle (2000)
    Springer
    Acta diabetologica 37 (2000), S. 119-124 
    Details
    ISSN: 1432-5233
    Schlagwort(e): Key words Streptozotocin ; Diabetes ; Ventricular myocyte ; Cardiac muscle ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Contractile dysfunctions have been demonstrated in different experimental models of diabetes which have similar characteristics to many of the abnormalities found in the clinical setting. Administration of streptozotocin (STZ) to young adult rats induces β-cell necrosis of the pancreas which gives rise to hypoinsulinaemia and hyperglycaemia, features which are also seen in untreated type 1 clinical diabetes. We have investigated the chronic effects of STZ-induced diabetes on contraction in rat ventricular myocytes and ultrastructure of cardiac muscle. Diabetes was induced in male Wistar rats (230–270 g) with a single injection of STZ (60 mg kg−1). At 2 and 10 months after STZ treatment, the amplitude of contraction was larger in diabetic compared to control myocytes. Time to peak contraction was significantly longer at 2 months but appeared to normalise at 10 months after STZ treatment. In contrast, time to half relaxation of contraction was not significantly different after 2 months but was significantly reduced at 10 months after STZ treatment compared to control. Transmission electron microscope examination of cardiac muscle showed that the ultrastructure of cardiac muscle, especially structures associated with contraction, were not greatly altered after STZ treatment. Sarcomere lengths were not significantly different in papillary or ventricular muscle at 4 or 8 months after STZ treatment compared to control. Our data provide evidence that morphological defects in contractile myofilaments and associated structures cannot explain contractile dysfunctions seen in ventricular myocytes from STZ-treated animals.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s005920070013
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  • 20
    Digitale Medien
    Digitale Medien
    Effect of osmotic stress on tolerance of air-drying and cryopreservation ofArabidopsis thaliana suspension cells (2000)
    Springer
    Protoplasma 214 (2000), S. 227-243 
    Details
    ISSN: 1615-6102
    Schlagwort(e): Arabidopsis thaliana ; Cryopreservation ; Dehydration ; Thermal analysis ; Sucrose ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary Arabidopsis thaliana suspension cells were preserved in liquid nitrogen for over three years, using embedding of cells in calcium-alginate prior to subculture in sucrose-enriched medium, air-drying, and direct quenching in liquid nitrogen. Survival of cells reached 34%, yielding regrowth at the surface of all cryopreserved beads in less than 7 days. Following pretreatment and dehydration, the water content dropped from 2300% to 34% with respect to dry weight. Differential scanning calorimetry showed that glass transition occurred on cooling, followed by a slight crystallization event on rewarming. The survival of cells was independent of the cooling rate. The tolerance of the acute dehydration step increased progressively with sucrose pretreatment duration, indicating the requirement for adaptative cellular alterations. Ultrastructural studies revealed several changes in cells after sucrose pretreatment prolonged from 1 to 7 days: reversal of the initially plasmolyzed state, microvacuolation, numerous autophagic structures, scarcity of ribosomes, increase in number and size of starch grains. No cell division seemed to occur during this period. After air-drying and after a freeze-thaw cycle, followed by 24 h rehydration, regenerating cells had recovered a high level of ultrastructural organization and contained numerous polysomes suggesting an intense metabolic activity. Trehalose, a cryoprotective disaccharide not considered to be a metabolic substrate, yielded only 70% regrowth after freezing. Biochemical analysis showed that soluble sugars accumulated during the pretreatment, essentially sucrose or trehalose; the monosaccharide content also increased. In the light of these results, the action of sucrose in inducing freezing tolerance is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01279067
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  • 21
    Digitale Medien
    Digitale Medien
    Ultrastructure and anatomy of nematode-induced syncytia in roots of susceptible and resistant sugar beet (2000)
    Springer
    Protoplasma 211 (2000), S. 39-50 
    Details
    ISSN: 1615-6102
    Schlagwort(e): Beta vulgaris ; Cyst nematodes ; Histology ; Resistance mechanism ; Syncytium ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary Using susceptible and resistant sugar beet lines, comparative analyses of root histology and ultrastructure were made during invasion by nematodes and the induction and formation of specific feeding structures (syncytia).The resistant line carried the resistance geneHs1pro−1.Nematodes were able to invade and induce functional syncytia in roots of resistant and susceptible lines. However, syncytia in resistant roots were smaller and less hypertrophied. The vacuolar system of syncytia in susceptible plants contained many small vacuoles. In resistant plants vacuoles were larger but less numerous. Smooth endoplasmic reticulum prevailed in syncytial protoplasts of susceptible plants, whereas almost only rough endoplasmic reticulum occurred in syncytia in resistant plants. The most conspicuous and hitherto undescribed trait of syncytia in resistant roots was the initial appearance of loose, and later compact, aggregations of the endomembrane system which composed most of the endoplasmicreticulum system of syncytia at later stages. Syncytia in resistant plants usually degraded before the nematodes reached their adult stage. The appearance of membrane aggregations and the other resistance-specific features are discussed in relation to their possible effects on syncytium function and role in nematode resistance.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01279898
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  • 22
    Digitale Medien
    Digitale Medien
    Structural changes during early embryogenesis in wheat pollen (2000)
    Springer
    Protoplasma 211 (2000), S. 94-102 
    Details
    ISSN: 1615-6102
    Schlagwort(e): Androgenesis ; Embryogenesis ; Microspore culture ; Pollen ; Ultrastructure ; Wheat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary We have made a detailed cytological examination of the development of wheat embryoids, monitoring their initial divisions from two to ten cells by both light and electron microscopy. According to our observations the first embryogenic division is symmetrical. After the androgenesis induction treatment, there is a decrease in ribosome population with cells that have inactive nucleoli made up almost exclusively of a dense fibrillar component. This population is restored after initial embryogenic divisions. During the initial divisions the embryogenic pollen grains do not appear to change in size and the pollen wall remains intact. The exine undergoes no modification but the intine thickens, and we have observed that the thickness of the intine can be used as a cytological marker of androgenesis. The walls separating the cells obtained after embryogenic division contained numerous plasmodesmata. The beginnings of embryo polarization and cell differentiation could be made out in the very early pollen embryoids.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01279902
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  • 23
    Digitale Medien
    Digitale Medien
    Effects of glutathione on thiol redox systems, chromosomal aberrations, and the ultrastructure of meristematic root cells ofPicea abies (L.) Karst. (2000)
    Springer
    Protoplasma 212 (2000), S. 227-235 
    Details
    ISSN: 1615-6102
    Schlagwort(e): Glutathione ; Root ; Chromosomal aberration ; Ultrastructure ; Picea abies
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary Young spruce seedlings (Picea abies [L.] Karst.) grown in hydroponic culture were exposed to three different concentrations (50,100, and 500 μM) of reduced glutathione for 24 h. These physiologically relevant concentrations of glutathione had a multiple effect on the investigated tissue. Feeding of glutathione to roots increased the concentrations of thiols (glutathione, cysteine, and γ-glutamyl-cysteine) in roots, decreased the rate of cell divisions, induced mitotic abnormalities, and affected the cell ultrastructure. Electron micrographs showed effects such as advanced vacuolation, dilated rough-endoplasmic-reticulum cisternae, and separations of the plasma membrane from the cell wall.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01282923
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  • 24
    Digitale Medien
    Digitale Medien
    Morphological aspects of the neuronal ceroid lipofuscinoses (2000)
    Springer
    Neurological sciences 21 (2000), S. S27 
    Details
    ISSN: 1590-3478
    Schlagwort(e): Key words Neuronal ceroid lipofuscinoses ; Lipopigments ; Ultrastructure ; Classification ; Genes ; Neuronal loss
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Morphological aspects of the neuronal ceroid lipofuscinoses (NCL) encompass two main features: loss of nerve cells and accumulation of autofluorescent lipopigments within cellular compartments. The former requires histology and morphometry for assessment, while the latter necessitates fluorescence microscopy, electron microscopy, and immunohistochemistry. Accumulation of lipopigments is widespread throughout the central nervous system and extracerebrally. The latter feature enables diagnosis of NCL and its clinical subtype. Loss of neurons is most pronounced in cerebral and cerebellar cortices, in early childhood forms. In subcortical grey matter and in later-onset forms, juvenile and adult NCL, reduction in neurons and possible preceding dendritic pathology may only correctly be ascertained by age-matched, controlled morphometric investigations which, to date, have not yet completely assessed subcortical neuronal damage. Presently, clinical and morphological evaluations are mandatory for genetic analysis, genetic counselling, and prenatal diagnosis, the latter often being based on combined genetic and morphological studies.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s100720070037
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  • 25
    Digitale Medien
    Digitale Medien
    A cellular variant of supratentorial hemangioblastoma (2000)
    Springer
    Brain tumor pathology 17 (2000), S. 15-19 
    Details
    ISSN: 1861-387X
    Schlagwort(e): Hemangioblastoma ; Supratentorial tumor ; Immunohistochemistry ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Supratentorial hemangioblastomas are rarely seen, especially in children and adolescents. We report the case of a 17-year-old male with supratentorial hemangioblastoma. Neuroimaging demonstrated a cystic lesion within the right parietal lobe. Systemic examination revealed no abnormality. The lesion was not attached to the dura and was not associated with von Hippel-Lindau disease. It was very difficult to confirm the final diagnosis of this case, in spite of extensive examination by light microscopy, immunohistochemical studies, and electron microscopy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02478913
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  • 26
    Digitale Medien
    Digitale Medien
    The development of the ovary in the grasshopper, Melanoplus differentialis (acrididae; orthoptera)The author is indebted to the National Research Council for a Fellowship during the year 1929-1930 during which the work herein described was partially completed; also, to the Marine Biological Laboratory, Woods Hole, Massachusetts, for facilities for work during the summer of 1930. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 515-543 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Each indifferent genital rudiment in the grasshopper embryo is composed of the following: (1) a terminal filament membrane; (2) an epithelial plate of indifferent cells, the dorsal cell mass; (3) the central cell mass containing germ and indifferent cells; (4) the ventral cell strand, and, (5) a delicate, investing membrane, the outer limiting membrane. It is roughly spindle-shaped in transverse section and extends from the first to the eighth abdominal segments.In the sexual differentiation of the genital rudiment the dorsal cell mass is retained as a definite embryonic rudiment in the female, but becomes an indistinguishable part of the central cell mass in the male.Ovarian development is initiated in the dorsal cell mass area, where cell aggregations are formed. Each aggregation is ultimately surrounded by the ingrowing outer limiting membrane to form distinct cellular columns. A latero-ventrad extension of this ingrowing process into the central cell mass continues the column formation process into the latter and results in the formation of a distally tapering structure composed of indifferent cells distad and germ cells and indifferent cells proximad. This structure constitutes the rudimentary ovariole which finally differentiates to form the terminal filament, germarium, and vitellarium.The ovarian portion of the oviduct and the tubular connection between the ovariole and oviduct are differentiated from the ventral cell strand.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550305
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  • 27
    Digitale Medien
    Digitale Medien
    The mesodermal relations of the pars buccalis of the hypophysis in the duck (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 611-631 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This paper describes the cellular relations between the prechordal mesoderm and the hypophyseal analage in duck embryos from the first to the eighth day of incubation.At nineteen somites the ectoderm destined to form hypophysis is seen as a plate of cells lying under the mesodermal mass anterior to the notochord. It extends anteriorly in intimate contact with the base of the forebrain, and posteriorly for about the same distance to the oral membrane. Following the lateral growth of the prechordal mesoderm and the rapid overgrowth of the forebrain, Rathke's pouch is definitely outlined. The upward expansion of the pouch, concomitant with the lagging of some of the prechordal mesoderm in the midline, effects a very close relation between these cells and those at the tip of the pouch. With the lateral expansion of the premandibular head cavities, some of the mesoderm adheres to walls of Rathke's pouch in the form of rods or knobs. As development proceeds the inherent growth tendencies of ectoderm and mesoderm express themselves differently and the rods or knobs become constricted off from the pouch, forming in its vicinity vesicles which exhibit a definite lumen.The question of an entodermal contribution to the hypophysis in this form is briefly considered.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550309
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  • 28
    Digitale Medien
    Digitale Medien
    The distribution of chitin in an insect (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 51-58 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: By treating the clean skeletal tissue of an insect with concentrated KOH at 160° C., the contained chitin is converted to chitosan, and all pigmentation and admixtures are removed. The per cent distribution of chitin, expressed as chitosan, in the exoskeleton of the cockroach, Periplaneta fuliginosa, ranges from 37.65 in the dorsal abdomen to 18.22 in the hindwings. Other regions contain the following per cents: ventral abdomen, 37.11; metathoracic legs, 35.55; mesothoracic legs, 33.28; prothoracic legs, 32.24; pronotum, 31.55; head, 31.07; genitalia, 29.28; dorsal thorax, 29.07; ventral thorax, 28.33; antennae, 27.77; cerci, 25.65; and forewings, 19.99. Regional variations are constant in different individuals of the same species. The crop and gizzard contain 18.69 per cent; the hindgut, 18.15 per cent. The remainder of the alimentary tract contains no chitin. Traces of chitin are found in the trachea. No chitin is found in the egg-cases of this species. No correlation between chitin content and pigmentation or hardness is shown. Based on results from three trials, using thirty insects, the per cent of chitosan in the clean, dry chitinous material from the entire animal is 29.60; the per cent of chitosan based on the weight of the live animal averages 2.01.
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560104
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  • 29
    Digitale Medien
    Digitale Medien
    A study of the spermatozoon of the fowl, with particular reference to osmiophilic bodies in the sperm head (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 325-337 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The purpose of this study was to learn something of the nature of the bead-like bodies which occur in the head of the sperm of the fowl since it was found in a previous study that they are apparently affected in a characteristic manner by vitamin E deficiency.Staining tests indicate that these bodies are composed of fats and fatty acids since they respond to osmic acid and Nile blue sulphate. They are also impregnated with silver nitrate and hence may be associated with the so-called Golgi materials of the cell.The beads first appear as a complete single row but subsequently they undergo fragmentation and redistribution. The whole process is probably a final transitory step in sperm transformation.The presence of this fatty material may signify that the sperm of the fowl, in contrast to that of most other animals, carries a store of food material to support its activity after liberation. The sperm may also be the carrier of a definite amount of vitamin E. Furthermore, the presence of this material may offer an explanation of the high resistance of the testis of the fowl to vitamin E deficiency because, since this vitamin is fat soluble, the testis as a whole would probably receive a disproportionately large share of the vitamin E stores of the individual.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560207
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  • 30
    Digitale Medien
    Digitale Medien
    A cytological study on the liver of the rat, with special reference to the ‘intracellular blood canaliculi,’ inter- and intracellular bile canaliculi, mitochondria and Golgi apparatus (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 407-421 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: In sections from livers injected through the vascular system with Carter's carminegelatin or Berlin-blue gelatin masses at known, constant pressures, many cells were observed to contain ovoid or spherical bodies of the colored injection masses, similar to those described by Schäfer and his students, Herring and Simpson, as intracellular blood canaliculi.' In these livers practically all the cells were vacuolated. However, with livers injected with Berlin-blue gelatin mass dissolved in Locke's solution instead of distilled water, there were no intracellular masses and the cells appeared normal, though the sinusoids were completely filled with injection mass. The so-called ‘intracellular blood canaliculi’ described by Schäfer are interpreted as artefacts produced by a combination of factors, the most important of which is the difference in osmotic pressure. This is produced by the hypotonicity of the injection masses that are usually used, augmented perhaps by the effect of mechanical pressure used in administering the injection mass.Following impregnation of liver tissue by Golgi's rapid method, the usual network of intercellular bile canaliculi was revealed, but the presence of a permanent system of intracellular canaliculi was not observed. A few short, knobbed intracellular projections from the intercellular bile canaliculi were noticed; these probably represent the passage of secretion material into the intercellular bile canaliculi at the moment of excretion.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560211
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  • 31
    Digitale Medien
    Digitale Medien
    Early development in some sciuridaeContribution no. 234 from the Zoölogical Laboratory of Indiana University. Submitted in partial fulfillment of the requirements for the degree, Doctor of Philosophy, in the Department of Zoölogy in the Graduate School of Indiana University. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 477-511 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The early developmental history of Sciuridae (squirrel family), from the ovarian egg to the establishment of the germ layers, was studied in fixed material comprising ova and embryos from six species of five genera. No significant differences were noted in the major processes of development in the six species. Continuous diminution in the size of the ova occurs from the beginning of follicular vesiculation up to the early blastocyst stages. Corpora haemorrhagica are present in most of the recently ruptured follicles of all the species.Cleavage is regular, though adequal, up to the eight-cell stage, the blastomeres clustering into a compact mass. There is desquamation of cellular material from the periphery of the ovum between morula and blastocyst stages. At the same time cells within the blastocyst degenerate to add to the cavity originally formed by confluence of intercellular spaces. The cavity forms among the inner cells, an inner cell mass being left at one pole and an anti-embryonic mass at the other. The anti-embryonic cells produce much of the yolk-sac entoderm and contribute to the implantation mass. The latter mass forms a temporary attachment of the blastocyst to the uterine mucosa in these species. The definitive entoderm arises by migration and delamination of certain of the inner cell mass cells. A transitory notochordal canal, passing in a vertical plane through Hensen's node, is strongly suggested.
    Zusätzliches Material: 19 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560304
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  • 32
    Digitale Medien
    Digitale Medien
    On the arterial system of the common Indian rat-snake, Ptyas mucosus (Linn.) (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 533-575 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The arterial system of Ptyas mucosus (Linn.) reveals the following interesting features: (1) A prominent diverticulum given off from the inner antero-dorsal edge of the left auricle. (2) Ridge-like continuation of the median hanging valve of the sinus venosus lining the ventral edge of the opening of the right precaval vein. (3) Guarding of the opening of the pulmonary vein by a portion of the inter-auricular septum abutting against it. (4) Presence of two longitudinal trunks on either side of the hepatic portal vein formed by the hepatic branches of the hepato-oesophageal arteries, which, uniting with one another, form a peculiar arrangement looking almost like a looped chain. (5) A complete arterial circuit in the female formed by the combination of the genital, supra-renal, and the anterior-most renal arteries of either side. (6) Chain-like arrangement formed by the alternate bifurcation and union of the posterior-most part of the longitudinal fat-body artery and also by its lateral branches, which unite with it here and there after giving off twigs to the fat bodies. (7) A pair of small arteries (or in some cases only one) called ‘arteria complexa’ which take their origin from the dorsal aorta opposite the openings of the iliac veins into the afferent renals.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560306
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  • 33
    Digitale Medien
    Digitale Medien
    The developmental anatomy of male genitalia in Melanoplus differentialis (acrididae) orthoptera) (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 577-609 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: An investigation has been conducted to ascertain the relationship of certain structures in the embryo of the grasshopper known as Melanoplus differentialis with reproductive organs in the adult male.The order of development of these structures was traced through the entire life history.It was determined that they are the rudiments of certain reproductive organs and that the knowledge obtained serves as an aid in more accurately classifying insects.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550308
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  • 34
    Digitale Medien
    Digitale Medien
    The segregation of the germ cells in the grasshopper, Melanoplus differentialis (acrididae; orthoptera)Much of the work outlined in this paper was completed during the year 1929-1930 while the writer was a National Research Fellow in biology. I am indebted to the National Research Council for this courtesy. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 545-575 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The segregation of the germ cells is related in time and differentiation to the ectoderm (ventral plate), the inner germ-band layer (lower layer) and the mesenteron (entoderm) rudiments. The inner germ-band layer is formed by invagination of cells from a median blastoporic groove and by cellular proliferations among the invaginating cells and from the median line of the ectoderm immediately caudad of the blastoporic groove. The mesenteron material is derived from inner germ-band layer material associated with the internal ends of the stomodaeum and proctodaeum. The germ cells are segregated from the lateral margins of the abdominal lobe ectoderm in the region of the amnion attachment as segmentation of the abdominal lobe is initiated. They ultimately become separated from the ectoderm cells of the lateral wall and from the amnion and migrate in a passive manner onto the coelomic sacs where they become associated with the inner walls of the sacs. When the coelomic sacs unite the germ cells and the splanchnic wall mesoderm cells form two continuous cell strands from the first to the eighth abdominal segments, inclusive. These strands form the indifferent genital rudiments. An endeavor is made to correlate the segregation of the germ cells in the grasshopper with that of various other insects.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550306
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  • 35
    Digitale Medien
    Digitale Medien
    Masthead (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934) 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560101
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  • 36
    Digitale Medien
    Digitale Medien
    The homologies of the flexor and adductor muscles of the thigh (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 21-49 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The literature relating to the flexor and adductor muscles of the thigh and their nerve supplies, in Sphenodon, the lizards, crocodiles and mammals was correlated and new dissections made of animals belonging to the last three groups. All of these muscles can be traced as individual entities from animal to animal without loss or addition to their number, although splitting may occur. The attachments of the muscles and their relationships to one another and to the two heads of the gastrocnemius are the same in all the reptiles studied. In the mammals one group, including the adductor longus and magnus and the retractor femoralis, has migrated from the tibia between the two heads of the gastrocnemius onto the femur, and another from the ilium onto the vertebrae, the one migration being caused by expansion of the gastrocnemius, and the other by expansion of the gluteal muscles. A new lateral flexor mass has been formed from part of the reptilian ilio tibialis by migration down the fibula. The nerve supplies of the various muscles are not constant when traced from group to group, and it is suggested that a muscle receives its nerve supply from the nerve nearest to it in embryonic development, so that when a muscle has migrated the nerve supply is no longer a reliable guide to its homology.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560103
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  • 37
    Digitale Medien
    Digitale Medien
    The activity of the coelomic (germinal) epithelium of the male musk turtle, Sternotherus odoratus (Latreille)The material used in this study was collected and prepared in part at the Zoölogical Laboratories of the University of Michigan. The remainder of the material was prepared and the study was completed at the Zoölogy Department of the State University of Iowa. Acknowledgments for financial assistance are due to the administrators of the Faculty Research Fund of the University of Michigan and to the National Research Council Committee for Research in Problems of Sex as administered by Prof. E. Witschi. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 59-99 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Histological studies of testes of both immature and mature individuals show that the peritoneal epithelium does not give up its proliferative capacities with the completion of testis differentiation. Certain regions of the antimesorchial surface retain their activity and continue to contribute cellular elements during testis growth. Stromal cells, germ cells, and sections of or entire seminiferous tubules originate from the peritoneum in the form of cord-like ingrowths. In this form, the proliferations of the germinal epithelium of the testes are similar to and homologous with the continuous proliferations of the germinal epithelium of the ovary.In Sternotherus, both testis and ovary differentiate out of a bisexual primordium in which the deeper parts of the germinal epithelium form an ovarian cortex. Since the germinal epithelium persists as an active part of both ovary and testis, it must be responsive to the same physiological factors of female or male differentiation respectively. It is indifferent sexually and once the direction of sex differentiation is established, the response of the germinal epithelium is in the determined direction. Its activity is then to produce either seminiferous tubules or ovarian follicles, and is directly dependent upon the processes of embryonic sex differentiation and determination.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560105
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  • 38
    Digitale Medien
    Digitale Medien
    The development of the thymus bodies in necturus maculosus (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 295-323 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The primordia of the thymus bodies in Necturus begin to form in 7-mm. embryos. These structures arise as clumps of entodermal cells on the posterior dorsal portion of the first four visceral pouches; the first or last pouch, being rudimentary, fails to form such a primordium. All except the first of these primordia lose their connection with their respective pouches in the 16-mm. stage and lie free in the surrounding connective tissue. The primordium on the first pouch begins to show degenerative changes during that stage, losing connection with its pouch in the 23-mm. stage, finally to disappear altogether in 30-mm. specimens.The three remaining bodies continue to grow, but the second and third outstrip the fourth in development and begin to form Hassall's corpuscles in 32- to 34-mm. stages. Sections of 30-mm. Necturi show a few of these corpuscles fairly well developed and containing a faintly staining secretion. The fourth body remains relatively small a long time, not showing the Hassallian cysts until the animal is 60 mm. long. By shifting of positions and increasing in size, the three bodies come to lie in proximity, one behind the other, to form the definitive thymus gland of the adult. The gland lies embedded in the heavy musculature on top of the head in front of the gills.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560206
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  • 39
    Digitale Medien
    Digitale Medien
    The effects of vitamin E deficiency on the testis of the male fowl (Gallus domesticus) (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 339-359 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The effects of vitamin E deficiency in the fowl were observed in Rhode Island Red males over a period of approximately 2 years.Mating experiments showed that after 1 year on the E-free diet all of the males were capable of fertilizing ova, but that after 2 years some of the males were sterile.Sperm smears showed that shortly after the beginning of the experiment, many of the mature spermatozoa exhibited an abnormal condition of the nuclear material of the head, while others remained normal.In histological sections of the testes made at the end of the 2 years, conditions varied from almost normal to complete atrophy, the latter being a condition that has already been described in the male mammal. Moreover, the conditions in any given section were not uniform for even in an advanced stage of E deficiency there were small islands of apparently normal tissue. However, in this case, as in the mammal, the process of degeneration affects the mature sperm cells first and gradually works to the outside of the seminiferous tubule thus attacking the youngest maturation stages last.The results of the experiment point definitely to destruction of the testis under prolonged E-deficient conditions but it is also quite apparent that the testis of the fowl is extremely resistant to vitamin E deficiency.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560208
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  • 40
    Digitale Medien
    Digitale Medien
    The osteology of the haplimous fish Novumbra hubbsi schultz with comparative notes on related speciesThe author wishes to thank: Dr. Leonard P. Schultz for his keen interest and helpful advice throughout the course of this study, and for the loan of specimens of Novumbra, Dallia, Umbra and Esox from the collection of fishes, Department of Fisheries, University of Washington; Dr. Carl L. Hubbs, of the University of Michigan, for specimens of Umbra limi, Umbra pygmaea, and Esox vermiculatus; Mr. Arnie Suomela, of the U. S. Bureau of Fisheries, for specimens of Umbra pygmaea; and Dr. J. R. Norman, of the British Museum, for specimens of, and the loan of a skeleton of Umbra crameri. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 371-405 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This paper is an attempt to clear up the confusion concerning the osteological relationships among the Haplomous fishes.The osteology of Novumbra hubbsi was worked out by the dissection of numerous specimens. The various skeletal features found were compared with the osteology of Umbra limi, U. pygmaea, U. crameri, and Dallia pectoralis.A description of each skeletal element of Novumbra was made, followed by a description of the chief differences between it and the same structures in Umbra and in Dallia. No constant osteological differences were found between Umbra limi and U. pygmaea, and very few between these two species and Umbra crameri. Novumbra and Umbra have more in common with each other than either does with Dallia or Esox. The presence of postorbitals, postcranials, and the shape of the secondary shoulder girdle in Novumbra show it to be also closely related to Dallia and Esox.The relationships of the various forms are summarized in a synoptic key which lists the following groups: Order Haplomi. Superfamily I, Dallioidea; Family Dallidae; Genus and species, Dallia pectoralis. Superfamily II, Umbroidea; Family 1, Umbridae; Genus and species, Umbra limi, U. pygmaea and U. crameri; Family 2, Novumbridae; Genus and species, Novumbra hubbsi. Superfamily III, Esocoidea; Family Esocidae; Genus, Esox.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560210
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  • 41
    Digitale Medien
    Digitale Medien
    Chemoreceptors of blowflies (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 445-475 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This paper deals with the morphology of all the so-called gustatory and olfactory organs of blowflies, and describes tests conducted to determine whether these insects taste with their tarsi and smell with their antennae and palpi. Antennae bear two types of so-called olfactory hairs, while palpi bear only one. With the aid of an olfactometer it has been shown that antennae and palpi do not bear the olfactory organs.In order to explain the proboscis response, described by Minnich, it is not necessary to assume that tarsi bear gustatory organs, because: (1) a tarus bears no sense organs, except nine olfactory pores; (2) it is almost impossible to wet the tarsi with water or sugar water; and (3) when flies were in the proper nutritive condition and liquids were about 3 mm. from the tarsi, the insects were induced by a special method to exhibit the proboscis response. It was further clearly demonstrated by a similar method that tarsi can easily distinguish between chemically pure saccharose water and distilled water when these liquids are about 3 mm. from the tarsi. The responses, obtained by any method, are caused by two stimuli, one mechanical and the other olfactory. The act of touching the feet produces the initial stimulus and brings the liquids almost in contact with the olfactory pores on the tarsi.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560303
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  • 42
    Digitale Medien
    Digitale Medien
    Intravitam studies on the hemipteran, Leptocoris trivittatus. A description of the male reproductive organs and the aggregation and turning of the sperms (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 513-531 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: A study of the male reproductive organs of a hemipteron, Leptocoris trivittatus, has been made. The genital system, which consists of fan-shaped testes; the vasa deferentia, to which a single pair of accessory glands are attached; ejaculatory ducts and the copulatory apparatus, is described and photomicrographs of consecutive parts presented.Then an analysis of the method of aggregation and turning of the sperms is made by means of intravitam technic. Aggregation and turning commence in the early spermatid stage. A spherical cyst forms, the tails first grow centripetally and then push out toward the lower end of the cyst. This line of growth in the cyst moves the head ends of the spermatids to the upper end where aggregation gradually takes place.The cysts spiral up and across the follicles, the moving force being, probably, the elongating tails. Later they spiral down the follicle, development progressing rapidly. The descending bundles are mature sperm, held together by a cytoplasmic cap.The accessory gland secretes a milky substance which probably activates the sperm at a later stage. Peristalsis occurs in the wall of the gland and duct.The process of massing sperm into bundles before copulation insures effective translocation. Then peristalsis and movement of tubular fluids carry the sperm down the duct to the copulatory apparatus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560305
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  • 43
    Digitale Medien
    Digitale Medien
    Localization of mineral ash in the organelles and cytoplasmic components of paramecium (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 421-433 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Paramecium caudatum was studied by micro-incineration, by stained control sections, by vital staining, and by osmic impregnation. It was found that a slow initial heating and a slow cooling after incineration greatly reduce the amount of distortion and shrinkage in the incinerated specimens. Most of the cytoplasmic components and organelles, including vacuome, chondriome, cilia, and basal granules, trichocysts, food vacuoles, and the nuclei, could be identified by their ash. No ash is found in the pellicle and only a small amount in the hyaloplasm. None of the osmiophilic components such as granules or the walls of the contractile vacuole could be identified in the incinerated specimens with certainty. The larger amount of ash in the endoplasm as compared with the ectoplasm is due to the large number of granules in the former region. The nucleus and some of the granules near the nucleus show traces of iron.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550302
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  • 44
    Digitale Medien
    Digitale Medien
    Studies upon regeneration. I. The constrasting powers of regeneration in planaria and procotylaSupported by a grant from the Committee on Radiation, National Research Council. Acknowledgments are also due to Keio University, Tokyo, Japan, for assistance given the senior author during his service as visiting professor, 1932-1933. The present paper is introductory to studies of the effects of radiation upon the normal structures and activities here described. A number of individuals have assisted in varying degrees in these investigations. Since work present paper, her name appears as a joint author. Certain work by6 C. D. Turner was similarly helpful. The senior author, who has thus supplemented his own studies of the material, has written the paper and assumes responsibility for the observations and their interpretation. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 477-513 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: When sexually mature Procotyla fluviatilis Leidy (commonly but erroneously known as Dendrocoelum lacteum) are cut transversely into head, pharyngeal, and tail pieces of about equal length, the head and pharyngeal pieces fail to regenerate in a large percentage of cases and tail pieces never regenerate. When regeneration occurs in head and pharyngeal pieces it is somewhat slower than in similar pieces of Planaria maculata Leidy and Planaria agilis Stringer with which comparisons were made. Cutting mature Procotyla into larger numbers of pieces usually results in death of all, although smaller pieces from prepharyngeal regions sometimes regenerate. Juvenile P. fluviatilis have greater powers of regeneration, as shown by cutting head and pharyngeal regions into greater numbers of pieces, but tail pieces do not regenerate. These observations confirm and extend those of earlier investigators. Such a restricted power of regeneration contrasts with well-known powers in P. maculata and P. agilis. Counts of formative cells, from which new parts arise in all three species and which are regarded by the authors as a persistent embryonic stock, indicate about 8.5 such cells in P. maculata to 1 in P. fluviatilis per unit area. It is concluded that regeneration in planarians is correlated with numbers of such formative cells and that histological factors are no less important than physiological ones. The paper is preliminary to a study of effects of x-rays upon regeneration.
    Zusätzliches Material: 15 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550304
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  • 45
    Digitale Medien
    Digitale Medien
    Studies on the spermatocyte divisions in ascaris megalocephala; with special reference to the central bodies, Golgi complex and mitochondria (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 435-475 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The centrioles are recognized early in the prophase of the primary spermatocyte. They soon become double and migrate around the nucleus in opposite directions. As this is completed the nuclear membrane breaks down and spindle fibers appear. The centrioles divide in the metaphase at a time when the centrosome is still perfectly spherical. The centrosome divides in the anaphase, giving the two centers for the second division. The centriole disappears in the spermatid and cannot be seen in later stages. The behavior of the centers during the spermatocyte divisions is strikingly like that of the egg centers and other types of mitoses. Therefore, it is concluded that the centrioles of the spermatocytes are not to be regarded as different from the centrioles in other types of mitoses.The Golgi bodies increase in number and size during the growth period of the cell. They are usually found in the shape of rings. From these rings are produced the refringent granules which fuse in the late spermatid to form those of the mature sperm. It is therefore concluded that this process represents the formation of the acrosome. The mitochondria show little change during the maturation divisions. In the late spermatid they aggregate around the nucleus and become vesiculated. This is interpreted as the formation of the prenebenkern.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550303
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  • 46
    Digitale Medien
    Digitale Medien
    Cytology of Troglodytella abrassarti, an intestinal ciliate of the chimpanzee (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 621-635 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560310
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  • 47
    Digitale Medien
    Digitale Medien
    Masthead (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934) 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550301
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  • 48
    Digitale Medien
    Digitale Medien
    Somatic mitoses of Drosophila melanogaster (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 125-155 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The chromosomes of D. melanogaster have been followed through the entire cycle of mitosis in ganglion cells. Primary constrictions exist at about the middle of the second and third chromosomes, at a sub-median position in the Y, at a sub-terminal in the X, and probably also at a sub-terminal position in the fourth chromosome. Secondary constrictions, in addition to those reported by Bridges, are sub-terminal in the arms of the second and third chromosomes. A pronounced sub-median secondary constriction in the left limb of the second chromosome offers a criterion for distinguishing between the second and third chromosomes, and between right and left arms of the second chromosome. The proximal secondary constriction in the X-chromosome and that in the short arm of the Y are associated with the normal development of the nucleolus. Anaphase chromosomes are longitudinally double, the split following the turns of the chromonemata. Metaphase and anaphase chromosomes are essentially isodiametric from end to end, except at the constrictions or indentures. Somatic pairing of chromosomes reaches its maximum expression during late prophases, both in male and female ganglion cells. The four chromatids of the tightly appressed homologues open out in two planes giving distinct chiasma-like configurations. Separation of the paired chromosomes is completed in late prophase, so that at metaphase the homologous chromosomes are not in contact.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560107
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  • 49
    Digitale Medien
    Digitale Medien
    The cytology of the corpora lutea of the eweA thesis submitted from the Department of Zoölogy for the degree of Doctor of Philosophy at the University of Missouri. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 181-202 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The cytology of corpora lutea of non-pregnant ewes is described with reference to the origin, structure, fate, and function of these organs. The lutein cells, characteristic of corpora lutea, are derived from the cells of the stratum granulosum of the Graafian follicle; connective-tissue cells, embryonic cells, and non-striated muscle cells, from the theca interna; and erythrocytes, leucocytes, and histiocytes, from the blood stream. The lutein cells undergo changes in size, nuclear structure, and cytoplasmic inclusions correlated with the period in the estrous cycle and disappear during retrogression. Although secretory products have not been identified, a secretory function is postulated on the basis of the structure of the cell.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560109
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  • 50
    Digitale Medien
    Digitale Medien
    Localization of mineral ash in the organelles of trichonympha, a hypermastigote flagellate from zootermopsis angusticollis (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 231-241 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The three species of Trichonympha found in Zootermopsis angusticollis were studied by micro-incineration, by control sections, and by Macallum's methods for iron and calcium. The mineral ash is concentrated in the neuromotor system, chromatin, nuclear membrane, the posterior end where ingestion takes place, and in cytoplasmic granules. Micro-incineration and Macallum's Prussian blue method reveal iron in the chromatin alone; Macallum's haematoxylin gives a positive test for iron in the chromatin, rostrum, neuromotor fibrils, etc. It probably is not as specific as the other methods. The two staining methods give negative tests for iron except after acid hydrolysis. Calcium is present in the chromatin, neuromotor system, posterior region of the body, and in many endoplasmic granules. The localization of calcium is correlated with the localization of normally gelated regions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560203
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  • 51
    Digitale Medien
    Digitale Medien
    Masthead (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934) 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560201
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  • 52
    Digitale Medien
    Digitale Medien
    Cytological studies of the epidermis of Rana pipiens and Rana clamitans tadpoles, with special reference to the figures of Eberth (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 213-229 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The conspicuous intracellular fibers (figures of Eberth) which are present in the basal epidermal cells of Rana pipiens and Rana clamitans tadpoles are thought to be connective tissue branches from the corium. They are not believed to represent fused mitochondria as concluded by Saguchi ('13). Their probable function is to furnish support to the basal epidermal cells and to strengthen the connection of the epithelial layer to the corium.It is believed that fully developed tadpole skin, before the period of metamorphosis has begun, consists of only two layers of cells, although there may appear to be more. Each of these layers is believed to be self-maintaining by mitotic division within the individual layer. The basal layer apparently does not furnish cells to the outer layer, nor was any evidence found that the outer layer is sloughed during the larval period.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560202
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  • 53
    Digitale Medien
    Digitale Medien
    Caste determination and differentiation with special reference to the genus reticulitermes (Isoptera) (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 267-293 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The results of recent investigations concerning caste determination among termites have been briefly reviewed with emphasis upon the work of Thompson ('17). From examination of new data upon the development of Reticulitermes arenincola Goellner, R. flavipes (Kollar), and R. tibialis Banks, and of Thompson's original R. flavipes material, I am unable to substantiate her claim that the sterile and reproductive castes are separable into two distinct groups at the time of hatching. I could distinguish them first in stadium three and suggest that the second stadium may be a critical period in differentiation. From evidence to date, it must be granted that both intrinsic and extrinsic factors may play a role in the production of castes. The delay in appearance of demonstrable caste differences until the third stadium in the genus Reticulitermes at least admits of an opportunity for extrinsic factors to be effective. Growth and metamorphosis of various structures which ultimately lead to the three differentiated castes have been followed through successive stadia. Gynandromorphs and intercastes among social insects give indication of the physiological and genetic factors influencing both morphological and behavior differences among castes.
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560205
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  • 54
    Digitale Medien
    Digitale Medien
    Erratum (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 565-565 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050550307
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  • 55
    Digitale Medien
    Digitale Medien
    The development of the posterior cardinal veins in relation to the swim bladder in Lepidosteus (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 1-19 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The origin and development of the posterior cardinals and associated veins in relation to the swim bladder, as well as their morphology, have been studied in Lepidosteus. The posterior cardinals develop, beginning in the 4-mm. stage, as sinuses in the mesenchyme dorsal to the gut and near the mesonephori. A pneumatic vein appears first in the 13-mm. stage. It collects from the posterior portion of the swim bladder and empties into the right posterior cardinal. In the younger stages the caudal vein empties directly into the posterior cardinals as is the case in the adult cyclostome, but by the 58-mm. stage it has joined veins dorsal to the mesonephori forming a renal portal system. An anal vein appears in the region of the anus and joins the caudal. Later, with the development of the renal portal system, the anal separates from the caudal to become the single posterior extension of the posterior cardinals. The posterior portion of the right cardinal contributes largely to the development of an abdominal portal vein extending from the posterior root of the right posterior cardinal to the liver. These relationships of the posterior cardinals differ from those found in other fishes, due perhaps to the function of the right cardinal and its pneumatic branch in collecting blood from the swim bladder.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560102
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  • 56
    Digitale Medien
    Digitale Medien
    Staining reactions of protoplasm and its formed components. A cytological and biochemical study (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 101-123 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Chemical analyses of the lipoids in fresh and autolyzed pancreas of the cat have been correlated with the staining reactions of sections of this organ preserved by three cytological methods. Quantities of total fats and of phospholipins, the iodine numbers of total fats and of phospholipins, and the free fatty acid numbers were determined. None of the methods of fixation used reveals the total fat content of the tissue. The intensity of staining of material fixed by Helly's method and stained with acid fuchsin is dependent on the phospholipins of the tissue, but the exact nature of the relationship is not certain. The intensity of staining of material preserved by Champy's method and stained with acid fuchsin can be correlated with the iodine number of the phospholipins of the cells. The degree of blackness of sections preserved by the Kolatchev-Nassonov method can be correlated with the iodine number of the phospholipins of the cells. The free fatty acid content is probably also a significant factor. The methods demonstrate lipoids qualitatively rather than quantitatively. Only physiologically similar cells may justifiably be compared by the cytological methods studied.
    Zusätzliches Material: 6 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560106
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  • 57
    Digitale Medien
    Digitale Medien
    The material continuity and individuality of the somatic chromosomes of Ambystoma tigrinum, with special reference to the nucleolus as a chromosomal component (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 157-179 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Two features of this study have furnished direct evidence for the material continuity and individuality of the chromosomes in the epithelial cells of the larvae of Ambystoma tigrinum (1) the tracing of the complete history of a specific chromosome, the nucleolus-containing chromosome, throughout the successive stages of mitosis and interkinesis, (2) the following of the exact parallelism in behavior (during mitosis) of the chromosomes in a given nuclear group with that in a single chromosome which has been isolated in the cytoplasm from the main chromosomal complex.Each of the two nucleoli is subterminally located in the short arm of one of two particular V-shaped chromosomes. The latter are probably homologues.78: In this subterminal chromosomal position the nucleolus exhibits in fixed and stained preparations an achromatic character in late prophase, metaphase, anaphase and early telophase, while it presents itself as a chromatic element in middle telophase, late telophase, interkinesis and early prophase.The nucleolus is not a simple homogeneous body, but rather a complex structure, the nature of which is revealed in the study of its evolution during the chromatic phase of its cycle in mitosis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560108
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  • 58
    Digitale Medien
    Digitale Medien
    Measurements of the skull and of some of the long bones of the muskrat (Ondatra zibethicus cinnamominus) (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 203-212 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The skull, mandible, and five pairs of long bones from the skeletons of 125 muskrats were weighed and measured. Each bone of the pairs of long bones was weighed and measured separately. Thirteen dimensions of the skull were determined.The long bones are slightly less variable in length than the skull dimensions. There is a rather wide range of variation in the thirteen dimensions of the skull, with the length and breadth of the skull less variable than the lengths of the long bones.The coefficients of correlation show that the weight of the skull is a good index to the weights of the long bones. The skull length has likewise high correlations with the lengths of the long bones and the longitudinal dimensions of the skull, with the exception of the palatine slits. The transverse diameters are not significantly correlated with the skull length.The long bones are asymmetrical in weight and length. They are longer more frequently on the left side and all except the tibia are heavier more frequently on the left side.
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560110
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  • 59
    Digitale Medien
    Digitale Medien
    A study of the development of the cochlea and cochlearis in the fetal albino rat (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 243-265 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The position of the inner ear and its relation to surrounding structures in the fetal head is ascertained. The growth and shape change of the cochlea is followed and measured. The change in size and appearance of the ductus cochlearis has been followed througout the various fetal stages. The growth and development of the scala vestibuli and scala tympani have been noted. The size and shape of the cells of the organs of Corti and the development and attachments of the tectorial membrane have been measured. The growth and developmental relationships of the tunnel of Corti have been followed. The growth and time of appearance of the organs with their relationship to hearing have been treated. The type of cell structure and the various structural changes throughout the development have been noted and correlated with the growth and size of the structure as a whole. The repidity of growth of all separate parts has been correlated and united to show the extent of development of the newborn rat inner ear.
    Zusätzliches Material: 9 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560204
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  • 60
    Digitale Medien
    Digitale Medien
    The idiochromosomes of an earwig, Labidura riparia (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 361-369 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The diploid number of chromosomes of a species of Indian earwigs, Labidura riparia, is fourteen; six pairs of autosomes with X and Y idiochromosomes for the male; six pairs of autosomes with X and X for the female.The chromosome distribution is normal, and constant for all the individuals studied.X and Y are derived from a single chromatin nucleolus of the early growth period which assumes a clavate form later, and remains in the same form till the metaphase of the primary spermatocyte is reached.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560209
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  • 61
    Digitale Medien
    Digitale Medien
    Masthead (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934) 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560301
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  • 62
    Digitale Medien
    Digitale Medien
    A study of the chromosomes of Xiphophorus, Platypoecilus and of Xiphophorus-Platypoecilus hybrids during spermatogenesisThe writer wishes to acknowledge his indebtedness to Dr. C. L. Turner for advice and assistance. (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 423-443 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: During spermatogonial stages in Xiphophorus and Platypoecilus maculatus and Platypoecilus couchiana and in the hybrid, two distinct types of cells are observed, a large lightly staining primary spermatogonium and a smaller deeply staining secondary spermatogonium. Chromosomes of primary spermatogonia of Platypoecilus maculatus and Platypoecilus couchiana differ somewhat from those of Xiphophorus helleri and Xiphophorus jalapa, but are very similar to those of the hybrid at this stage.Chromosomes of Xiphophorus at this stage are long and thin, while those of Platypoecilus and of the hybrid are somewhat short and thick. Visible chromosome differences appear only during the primary spermatogonial stages.The haploid group of chromosomes, numbering twenty-four in the hybrid, so resembles that of Xiphophorus and of these two species of Platypoecilus in both number and morphological characteristics during the primary spermatocyte division as to be practically indistinguishable from either. Persistent lagging of one large chromosome as it comes upon the equatorial plate during the primary spermatocyte division is very noticeable. Precocious division of this chromosome and the advancing of its two daughter components to the poles of the spindle in advance of other chromosomes indicates that this chromosome may be a sex chromosome. The fact that two daughter components are identical morphologically and that each secondary spermatocyte receives one of them suggests that the male in Xiphophorus and in Platypoecilus is homogametic.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560302
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  • 63
    Digitale Medien
    Digitale Medien
    Somatic synapsis in chironomus, with special reference to the individuality of the chromosomes (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 577-591 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The nuclear band of the cells of the salivary glands of Chironomus larvae regularly consists of four segments or chromosomes. Each of these may be recognized by its characteristic distribution of chromatin discs of various sizes. When nucleolar elements are present they have a definite location in relation to the chromation discs of a certain chromosome. The diploid number of chromosomes is eight; therefore, the four segments in the cells of the salivary glands represent four pairs of homologous chromosomes in somatic synapsis which here is not a simple approximation but an accurate pairing part by part of the homologous chromosomes.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560307
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  • 64
    Digitale Medien
    Digitale Medien
    Insect development. VII. Early stages in the development of grasshopper eggs of known age and with a known temperature history (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 593-601 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The rate of maturation and of development during the first 4 days has been followed in Melanoplus differentialis eggs (from mated females) collected (1) just before they were laid, or (2) immediately after oviposition had been completed and (1) either fixed at once, or (2) after incubation at 25°C. for definite periods.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560308
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  • 65
    Digitale Medien
    Digitale Medien
    Insect development. VIII. Maturation and early development of unfertilized grasshopper eggs (1934)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 603-619 
    Details
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Maturation and early cleavage in unfertilized Melanoplus differentialis eggs have been followed with material secured immediately before as well as after oviposition, and (1) fixed at once, or (2) held in an incubator at 25°C. and, subsequently, fixed at selected intervals. Eggs ready to be laid were all found in the metaphase of the first maturation division. The second polar body is given off (at 25°C.) within 5 to 7 hours after laying. Meiosis appears to be unaffected by the absence of the sperm nucleus and proceeds at the same rate as in fertilized eggs. No morphological differences could be found between the process here and in eggs from mated females.During early cleavage, or later, the diploid number of chromosomes may be restored in some (or perhaps all) cells of the embryo.Development begins in the greater number of these unfertilized eggs but is successfully completed in only a very few.
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jmor.1050560309
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  • 66
    Digitale Medien
    Digitale Medien
    The structure of the human vaginal mucosa in relation to the menstrual cycle and to pregnancy (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 54 (1934), S. 27-85 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1000540103
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  • 67
    Digitale Medien
    Digitale Medien
    The distribution of parietal cells in the stomach: A histotopographic studyAbridgment of thesis submitted to the faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of Master of Science in Medicine, March, 1933. Submitted for publication June 7, 1933. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 54 (1934), S. 87-114 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1000540104
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  • 68
    Digitale Medien
    Digitale Medien
    On the morphology of the omentum, with especial reference to its lymphatics (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 54 (1934), S. 203-228 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 12 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1000540203
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  • 69
    Digitale Medien
    Digitale Medien
    The skeletal development of the anterior limb of the guinea-pig, Cavia cobaya Cuv., from the 25-day embryo to the 161-day post natal guinea-pigContribution from the Zoölogy Department of the Kansas State College of Agriculture and Applied Science, No. 160. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 54 (1934), S. 315-331 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1000540206
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  • 70
    Digitale Medien
    Digitale Medien
    The differentiation of entire young rabbit embryos in omental grafts (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 54 (1934), S. 347-381 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1000540302
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  • 71
    Digitale Medien
    Digitale Medien
    X-irradiation of the ovaries of guinea-pigs and its effect on subsequent pregnancies (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 55 (1934), S. 1-45 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1000550102
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  • 72
    Digitale Medien
    Digitale Medien
    Responses of the reproductive system of hypophysectomized and normal rats to injections of pregnancy-urine extracts. I. The maleAided by a grant from the Committee for Research in Problems of Sex, The National Research Council. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 145-173 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580207
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  • 73
    Digitale Medien
    Digitale Medien
    Responses of the reproductive system of hypophysectomized rats to injections of pregnancy-urine extracts. II. The femaleAided by a grant from the National Research Council, Committee on Problems of Sex. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 175-203 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580208
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  • 74
    Digitale Medien
    Digitale Medien
    The effects of ultraviolet irradiation on rachitic chickensSubmitted for publication September 8, 1933. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 205-216 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580209
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  • 75
    Digitale Medien
    Digitale Medien
    Thirty-first session: Proceedings, constitution and by-laws, officers and list of members (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 1-55 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580210
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  • 76
    Digitale Medien
    Digitale Medien
    A method for preparing frozen sections of infant cadavers (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 241-243 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580305
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  • 77
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    Digitale Medien
    Artificially induced ovulation in the cat (felis domestica)The writer gratefully acknowledges his indebtedness to Prof. C. H. Danforth for unfailing helpfulness throughout this investigation. His sincere thanks are due, also, to Dr. A. W. Meyer for his kindness in reading and criticising the manuscript. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 217-224 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580302
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  • 78
    Digitale Medien
    Digitale Medien
    A rare cardiac anomaly of a human fetus (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 245-248 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580306
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  • 79
    Digitale Medien
    Digitale Medien
    Studies on the somites of amblystoma punctatum. I. The replacement of the second, third, and fourth somites by the corresponding somites from older or younger donors (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 249-271 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 24 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580307
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  • 80
    Digitale Medien
    Digitale Medien
    Studies on the somites of Amblystoma punctatum. II. The result of the dorso-ventral reversal of the second, third and fourth somites (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 273-297 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 17 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580308
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  • 81
    Digitale Medien
    Digitale Medien
    The later development of the bursa pharyngea: Homo (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 303-319 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 27 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580310
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  • 82
    Digitale Medien
    Digitale Medien
    Masthead (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934) 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580401
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  • 83
    Digitale Medien
    Digitale Medien
    Secretory activity of the inner layer of the embryonic mid-brain of the chick, as revealed by tissue cultureAcknowledgment is due to Yale University for the grant of a Sterling Research Fellowship and to Doctor Harrison for extending the facilities of his laboratory to the author. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 299-302 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580309
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  • 84
    Digitale Medien
    Digitale Medien
    The ontogenetic history of the mitochondria and Golgi network of the hepatic cell of the chick (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 321-347 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 36 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580402
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  • 85
    Digitale Medien
    Digitale Medien
    Histochemical studies on the mammalian kidney. I. The glomerular elimination of ferrocyanide in the rabbit, and some related problemsGrateful acknowledgment is made to The Chemical Foundation for its support which made this work possible, received through the Julius Stieglitz Fund for Research in Chemistry Applied to Medicine. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 349-367 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580403
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  • 86
    Digitale Medien
    Digitale Medien
    The transplantation of the adult hypophysis into young salamander larvaeFor the photographs and photomicrographs which illustrate this paper, the author is indebted to Mr. M. C. Orser. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 415-429 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580406
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  • 87
    Digitale Medien
    Digitale Medien
    Histochemical studies on the mammalian kidney. II. The glomerular elimination of uric acid in the rabbitGrateful acknowledgment is made to The Chemical Foundation for its support which made this work possible, received through the Julius Stieglitz Fund for Research in Chemistry Applied to Medicine. I wish also to acknowledge the interest of Dr. Edward J. Stieglitz. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 369-385 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580404
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  • 88
    Digitale Medien
    Digitale Medien
    Experiments on developing rats. I. Limits of foetal regeneration; behavior of embryonic material in abnormal environments (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 58 (1934), S. 387-413 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090580405
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  • 89
    Digitale Medien
    Digitale Medien
    The mitotic index of the thyroid gland in guinea pig and ratThese investigations were carried out with the aid of a grant for research in science made to Washington University by the Rockefeller Foundation. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 5-14 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590103
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  • 90
    Digitale Medien
    Digitale Medien
    An infra-hyoid muscular anomaly in man (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 41-45 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590106
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  • 91
    Digitale Medien
    Digitale Medien
    Bone changes due to lathyrism in rats (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 283-295 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590303
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  • 92
    Digitale Medien
    Digitale Medien
    Hemal nodes in man (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 297-310 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590304
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  • 93
    Digitale Medien
    Digitale Medien
    The supracondyloid variation in the human embryo (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 315-333 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590306
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  • 94
    Digitale Medien
    Digitale Medien
    The homology of the presemimembranosus muscle in some rodents (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 311-314 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590305
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  • 95
    Digitale Medien
    Digitale Medien
    The effects of ultracentrifuging upon the Golgi apparatus in the uterine gland cells (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 363-373 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590309
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  • 96
    Digitale Medien
    Digitale Medien
    The effect of anterior lobe extract or concentrated human urine of pregnancy upon the early part of gestation in the rabbit (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 375-381 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590310
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  • 97
    Digitale Medien
    Digitale Medien
    A new formula for injecting cadavers (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 393-394 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590312
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  • 98
    Digitale Medien
    Digitale Medien
    Some facts regarding growth of the Wistar rat under standard conditions in Britain (derivative Edinburgh stock)These observations were made in connection with experiments performed during the tenure of a Carnegie Research Scholarship. (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. 383-391 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 8 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590311
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  • 99
    Digitale Medien
    Digitale Medien
    New books and publications (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934), S. A394 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590313
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  • 100
    Digitale Medien
    Digitale Medien
    Masthead (1934)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 59 (1934) 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1090590401
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