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  • 1995-1999  (45,407)
  • 1985-1989  (50,558)
  • 1955-1959  (14,833)
  • 1890-1899  (12,811)
  • Chemistry  (108,184)
  • Polymer and Materials Science  (35,207)
  • Life and Medical Sciences  (14,279)
  • ddc:510
  • gene transfer
  • genetic engineering
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Material
Years
Year
Keywords
Language
  • 1
    Electronic Resource
    Electronic Resource
    Keeping Up with the Cloneses -- Issues in Human Cloning (1999)
    Springer
    The journal of ethics 3 (1999), S. 51-71 
    Details
    ISSN: 1572-8609
    Keywords: biotechnology ; cloning ; ethics of biotechnology ; ethics of cloning ; ethics of human cloning ; ethics for reproductive technology ; genetic engineering ; human cloning ; religious ethics ; reproductive technology ; secular ethics ; social ethics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Philosophy
    Notes: Abstract The advent of cloning animals has created a maelstrom of social concern about the “ethical issues” associated with the possibility of cloning humans. When the “ethical concerns” are clearly examined, however, many of them turn out to be less matters of rational ethics than knee-jerk emotion, religious bias, or fear of that which is not understood. Three categories of real and spurious ethical concerns are presented and discussed: 1) that cloning is intrinsically wrong, 2) that cloning must lead to bad consequences, and 3) that cloning harms the organism generated. The need for a rational ethical framework for discussing biotechnological advances is presented and defended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009775715165
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  • 2
    Electronic Resource
    Electronic Resource
    Analysis of otolith chemistry in Nassau grouper (Epinephelus striatus) from the Bahamas and Belize using solution-based ICP-MS (1999)
    Springer
    Coral reefs 18 (1999), S. 171-178 
    Details
    ISSN: 1432-0975
    Keywords: Key words Otolith ; Chemistry ; ICP-MS ; Stock discrimination ; Epinephelus striatus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract  We examined the utility of otolith minor and trace element chemistry, assayed with inductively coupled plasma mass spectrometry (ICP-MS), as a means of delineating population structure in the Nassau grouper (Epinephelus striatus). We characterized the elemental composition of otoliths collected in 1993 from three locations in Exuma Sound, Bahamas and from Glover Reef, Belize in 1995. A single location in Exuma Sound was sampled in 1994 to test temporal variability in otolith composition. Five elements (Ca, Zn, Sr, Ba and Pb) were routinely detected, at levels significantly above background, by solution-based ICP-MS. Results from analysis of variance of elemental data, expressed as a ratio to Ca, indicated that there were no significant differences among the Exuma locations for any element, but significant variability was found between Glover Reef and the pooled Exuma localities for Zn/Ca, Sr/Ca and Ba/Ca ratios. Significant inter-annual differences at one Exuma Sound location was restricted to Ba/Ca ratios. Discriminant function analysis correctly classified 86% and 95% of the Belize and pooled Exuma sites, respectively. Otoliths from Belize were characterized by low Zn/Ca and high Ba/Ca and Pb/Ca ratios compared to otoliths from fish collected in Exuma Sound. Although differences in Ba levels may be related to upwelling at Glover Reef, more data are needed to definitely link otolith composition with regional differences in water chemistry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003380050176
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  • 3
    Electronic Resource
    Electronic Resource
    Stable Long Term Germ-Line Transmission of Transgene Integration Sites in Mice (1999)
    Springer
    Transgenic research 8 (1999), S. 1-8 
    Details
    ISSN: 1573-9368
    Keywords: gene construct ; gene transfer ; heritability ; marker gene ; pigmentation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Transgenic mice provide a valuable tool in all fields of basic and applied biological and medical research. In this study, we describe the fate of integrated transgenes in the mammalian host genome over a large number of generations. The stability of the germ-line transmission of integrated tyrosinase transgene copies was monitored up to generation F20 in a large number of individuals from seven transgenic mouse lines. Phenotypic and molecular genetic analysis of the offspring both within the different lines and in cross-breeding experiments revealed the high stability of the transgene integration sites in mice. Only very few individuals were affected by a transgene copy loss. These results indicate that, once homozygous transgenic lines are established, breeding programs can be continued to a high number of generations without further stringent molecular genetic analysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008824028100
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  • 4
    Electronic Resource
    Electronic Resource
    Gene transfer into canine myoblasts (1999)
    Springer
    Cytotechnology 30 (1999), S. 181-189 
    Details
    ISSN: 1573-0778
    Keywords: culture ; dog ; Duchenne dystrophy ; gene transfer ; satellite cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract We have developed and characterized cultures of healthy and dystrophic canine myoblasts for the evaluation of various gene transfer protocols. The number of desmin-positive myoblasts was elevated (〉〉80%) in cultures of myoblasts obtained from different muscle territories, the diaphragm muscle giving rise to the purest cultures. Myoblasts from dogs turned out to be a very convenient source of well transfectable and transducible cells. Transfection with plasmid DNA allowed efficient transgene expression (50% of β-galactosidase positive cells and about 375 ng luciferase/mg protein after transfection with a calcium phosphate-precipitated plasmid). Infection with high concentrations of adenoviral and retroviral vectors allowed transgene (β-galactosidase or mini-dystrophin) detection in about 75 to 90% of the canine cells. Therefore, primary dog myoblast cultures represent a useful in vitro model for viral and non-viral gene delivery, as well as for functional evaluation and cell grafting with applications in genetic diseases, vaccination or production of circulating therapeutic proteins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008026913715
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  • 5
    Electronic Resource
    Electronic Resource
    Wounding by bombardment yields highly efficient Agrobacterium-mediated transformation of carnation (Dianthus caryophyllus L.) (1999)
    Springer
    Molecular breeding 5 (1999), S. 367-375 
    Details
    ISSN: 1572-9788
    Keywords: transgenic carnation ; genetic engineering ; microprojectile bombardment ; stable transformation ; kanamycin selection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Highly efficient Agrobacterium-mediated transformation of carnation (Dianthus caryophyllus L.) was obtained by first wounding stem explants via microprojectile bombardment. When this was followed by cocultivation with disarmed Agrobacterium in the dark, the transformation frequency-based on transient GUS expression-increased to over 10-fold that of explants wounded by other means and cocultivated under constant light. Two cycles of regeneration/selection on kanamycin were employed to generate stably transformed carnation plants and eliminate chimeras: first, plantlets were regenerated from inoculated stem explants and then leaves from these plantlets were used to generate transgenes in a second selection cycle of adventitious shoot regeneration. Agrobacterium strain AGLO, carrying the binary vector pCGN7001 containing uidA and nptII genes, was used in the stable transformation experiments. The combination of wounding via bombardment, cocultivation in the dark and two cycles of kanamycin selection yielded an overall transformation efficiency of 1–2 transgenes per 10 stem explants for the three carnation varieties analyzed. Histochemical and molecular analyses of marker genes in T0 and T1 generations confirmed the transgenic nature of the selected plants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009671131200
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  • 6
    Electronic Resource
    Electronic Resource
    Adenovirus-mediated Gene Transfer of a Truncated Form of Fibroblast Growth Factor Receptor Inhibits Growth of Glioma Cells both In Vitro and In Vivo (1999)
    Springer
    Journal of neuro-oncology 44 (1999), S. 195-203 
    Details
    ISSN: 1573-7373
    Keywords: adenovirus ; dominant negative ; fibroblast growth factor receptor ; gene transfer ; glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Basic fibroblast growth factor (FGF-2) and high affinity FGF receptor (FGFR) have been detected in the nucleus as well as the cytoplasm of many human gliomas, and are known to stimulate cellular proliferation and angiogenesis in the tumors. To investigate the effects of inactivation of FGFR on the growth of malignant gliomas, we constructed a replication-deficient recombinant adenovirus vector encoding a truncated form of chicken FGFR1 (AxCA Δ FR). AxCA Δ FR-infected cells were confirmed to express truncated FGFR protein by immunoblotting and FGF-2-dependent clonogenicity of NIH3T3 cells was suppressed by infection with this virus vector. Then human malignant glioma cell lines U-251MG and T98G, both of which have been reported to express FGF-2 and FGFR, were infected with AxCA Δ FR. These infected cells showed nuclear as well as cytoplasmic expression of a truncated FGFR protein. Proliferation rate and the ability to form colonies in soft agar of the cells infected with this virus vector were significantly suppressed compared with those of uninfected and lacZ-expressing adenovirus-infected cells. Moreover, intratumoral injection of AxCA Δ FR significantly suppressed the subcutaneous tumor growth of the glioma cells in nude mice. We concluded that inactivation of the cytoplasmic and nuclear FGFR using this truncated FGFR-expressing adenovirus vector can inhibit the growth of malignant gliomas both in vitro and in vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006355014351
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  • 7
    Electronic Resource
    Electronic Resource
    Glycotargeting: Influence of the Sugar Moiety on Both the Uptake and the Intracellular Trafficking of Nucleic Acid Carried by Glycosylated Polymers (1999)
    Springer
    Bioscience reports 19 (1999), S. 125-132 
    Details
    ISSN: 1573-4935
    Keywords: Oligonucleotides ; gene transfer ; routing ; membrane lectins ; glycoconjugates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Nucleic acids (plasmids as well as oligonucleotides) used to specifically express or modulate the expression of a gene, must reach the cytosol and/or the nucleus. Several systems have been developed to increase their uptake and their efficiency. Glycosylated polylysines have been shown to specifically help nucleic acids to be taken up in cells expressing a given cell surface membrane lectin. However, it appeared that the efficiency of the imported nucleic acid was not directly related to the extent of the uptake. Indeed, some glycosylated polylysines bearing sugar moities which are poor ligands of the cell surface lectins of a given cell were found to be more efficient than those bearing better sugar ligands. The interpretation of this paradoxal result is discussed with regards to the nature of the compartment allowing the nucleic acid to cross the membrane and to be delivered in the cytosol on the one hand, and to the presence of intracellular lectins on the other hand.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1020114611517
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  • 8
    Electronic Resource
    Electronic Resource
    Genetic engineering of shikonin biosynthesis hairy root cultures of Lithospermum erythrorhizon transformed with the bacterial ubiC gene (1999)
    Springer
    Plant molecular biology 39 (1999), S. 683-693 
    Details
    ISSN: 1573-5028
    Keywords: genetic engineering ; 4-hydroxybenzoic acid glucoside ; Lithospermum erythrorhizon ; menisdaurin ; shikonin ; ubiC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The biosynthetic pathway to 4-hydroxybenzoate (4HB), a precursor of the naphthoquinone pigment shikonin, was modified in Lithospermum erythrorhizon hairy root cultures by introduction of the bacterial gene ubiC. This gene of Escherichia coli encodes chorismate pyruvate-lyase (CPL), an enzyme that converts chorismate into 4HB and is not normally present in plants. The ubiC gene was fused to the sequence for a chloroplast transit peptide and placed under control of a constitutive plant promoter. This construct was introduced into L. erythrorhizon by Agrobacterium rhizogenes-mediated transformation. The resulting hairy root cultures showed high CPL activity. 4HB produced by the CPL reaction was utilized for shikonin biosynthesis, as shown by in vivo inhibition of the native pathway to 4HB with 2-aminoindan-2-phosphonic acid (AIP), an inhibitor of phenylalanine ammonia-lyase. A feeding experiment with [1,7-13C2]shikimate showed that in the absence of AIP the artificially introduced CPL reaction contributed ca. 20% of the overall 4HB biosynthesis in the transgenic cultures. ubiC transformation did not lead to a statistically significant increase of shikonin formation, but to a 5-fold increase of the accumulation of menisdaurin, a nitrile glucoside which is presumably related to aromatic amino acid metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006185806390
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  • 9
    Electronic Resource
    Electronic Resource
    The S7 ribosomal protein gene is truncated and overlaps a cytochrome c biogenesis gene in pea mitochondria (1999)
    Springer
    Plant molecular biology 40 (1999), S. 91-97 
    Details
    ISSN: 1573-5028
    Keywords: cytochrome c biogenesis ; gene transfer ; mitochondria ; pea ; ribosomal protein ; soybean
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The pea mitochondrial genome contains a truncated rps7 gene lacking ca. 40 codons at its 5′ terminus. This single-copy sequence is immediately downstream of and slightly overlapping an actively transcribed and edited reading frame of 744 bp (designated ccb248) homologous to the bacterial helC gene which encodes a subunit of the ABC-type heme transporter involved in cytochrome c biogenesis. This region of mitochondrial DNA appears recombinogenic, and the carboxy-termini of helC-type proteins are predicted to vary in sequence and length among plants. Sequences corresponding to the 5′ coding region of rps7 were not detected elsewhere in the pea mitochondrial genome using wheat rps7 probes, and only a very short internal rps7 segment was observed in soybean mitochondrial DNA. The presence of rps7-homologous sequences in the nuclear genomes of pea and soybean is consistent with the recent transfer of a functional mitochondrial rps7 gene to the nucleus in certain plant lineages.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026499906338
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  • 10
    Electronic Resource
    Electronic Resource
    Mycoplasma-Mediated Uptake of the Exogenous Human BRCA1 Gene by Hatching Blastocysts (1999)
    Springer
    Journal of assisted reproduction and genetics 16 (1999), S. 546-550 
    Details
    ISSN: 1573-7330
    Keywords: breast cancer ; mycoplasma ; Ureaplasma urealyticum ; foreign DNA ; gene transfer ; transgenic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: Biological vectors for cell transfection are mainly viral in origin, with inherent shortcomings. Mycoplasmas are ubiquitous organisms that traverse cells easily. The objective was to determine if Ureaplasma urealyticum (T-mycoplasma) would vector exogenous BRCA1 DNA into blastocysts. Methods: Hatching mouse blastocysts (N = 70) were incubated in the presence of either viable or dead Ureaplasma urealyticum at 37°C for 1 hr. The blastocysts were exposed to human BRCA1 DNA lacking homology in the mouse genome for 2 hr, followed by DNase-I treatment and wash. Polymerase chain reaction and agarose gel electrophoresis analysis of amplified products were performed. Results: The BRCA1 gene was detected in the blastocysts only when viable Ureaplasma was present. PCR analyses of control Ureaplasma and untreated blastocysts were negative. Conclusion: Viable Ureaplasma organisms were shown to mediate the uptake of DNA fragments into blastocysts, resulting in transgenic mouse blastocysts with a normal human BRCA1 exon 11 gene.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1020553322073
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  • 11
    Electronic Resource
    Electronic Resource
    Tissue culture and Agrobacterium-mediated transformation of watercress (1999)
    Springer
    Plant cell, tissue and organ culture 58 (1999), S. 171-176 
    Details
    ISSN: 1573-5044
    Keywords: Bacillus thuringiensis Brassicaceae ; gene transfer ; insect resistance ; plant regeneration ; Rorippa nasturtium-aquaticum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Adventitious shoot regeneration could be obtained from more than 80% of the calluses initiated from stem explants of watercress (Rorippa nasturtium-aquaticum) by using an induction medium and a shoot regeneration medium. The induction medium contained 1.15 μM 2,4-dichlorophenoxyacetic acid and 5 μM thidiazuron; the shoot regeneration medium was composed of 0.5 μM thidiazuron and 2.25 μM 6-benzylaminopurine. This regeneration procedure was incorporated into an Agrobacterium-mediated transformation procedure for gene transfer into watercress. Factors affecting transformation included preculture, selection agents, use of tobacco nurse cells, and the length of coculture. A transgenic line of watercress transformed with a wild-type Bacillus thuringiensis insecticidal gene, cry1Ia3, was not toxic to larvae of the diamondback moth (Plutella xylostella), presumably due to premature polyadenylation of the transcript encoded by this gene in the plant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006399130272
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  • 12
    Electronic Resource
    Electronic Resource
    Questions about the complexity of chloroplast ribulose-1,5-bisphosphate carboxylase/oxygenase (1999)
    Springer
    Photosynthesis research 60 (1999), S. 29-42 
    Details
    ISSN: 1573-5079
    Keywords: enzyme catalysis ; evolution ; genetic engineering ; photosynthesis ; protein assembly ; protein degradation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco; EC 4.1.1.39) has played a central role in our understanding of chloroplast biogenesis and photosynthesis. In particular, its catalysis of the rate-limiting step of CO2 fixation, and the mutual competition of CO2 and O2 at the active site, makes Rubisco a prime focus for genetically engineering an increase in photosynthetic productivity. Although it remains difficult to manipulate the chloroplast-encoded large subunit and nuclear-encoded small subunit of crop plants, much has been learned about the structure/function relationships of Rubisco by expressing prokaryotic genes in Escherichia coli or by exploiting classical genetics and chloroplast transformation of the green alga Chlamydomonas reinhardtii. However, the complexity of chloroplast Rubisco in land plants cannot be completely addressed with the existing model organisms. Two subunits encoded in different genetic compartments have coevolved in the formation of the Rubisco holoenzyme, but the function of the small subunit remains largely unknown. The subunits are posttranslationally modified, assembled via a complex process, and degraded in regulated ways. There is also a second chloroplast protein, Rubisco activase, that is responsible for removing inhibitory molecules from the large-subunit active site. Many of these complex interactions and processes display species specificity. This means that attempts to engineer or discover a better Rubisco may be futile if one cannot transfer the better enzyme to a compatible host. We must frame the questions that address this problem of chloroplast-Rubisco complexity. We must work harder to find the answers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006240202051
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  • 13
    Electronic Resource
    Electronic Resource
    Intracellular fate and nuclear targeting of plasmid DNA (1999)
    Springer
    Cell biology and toxicology 15 (1999), S. 193-202 
    Details
    ISSN: 1573-6822
    Keywords: DNA ; gene transfer ; importin ; nuclear import ; nuclear localization signal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract One of the major steps limiting nonviral gene transfer efficiency is the entry of plasmid DNA from the cytoplasm into the nucleus of the transfected cells. The nuclear localization signal (NLS) of the SV40 large T antigen is known to efficiently induce nuclear targeting of proteins. We have developed two chemical strategies for covalent coupling of NLS peptides to plasmid DNA. One method involves a site-specific labeling of plasmid DNA by formation of a triple helix with an oligonucleotide–NLS peptide conjugate. After such modification with one NLS peptide per plasmid molecule, plasmid DNA remained fully active in cationic lipid-mediated transfection. In the other method, we randomly coupled 5–115 p-azidotetrafluorobenzyllissamine–NLS peptide molecules per plasmid DNA by photoactivation. Oligonucleotide–NLS and plasmid–lissamine–NLS conjugates interacted specifically with the NLS-receptor importin α. Plasmid–lissamine–NLS conjugates were not detected in the nucleus, after cytoplasmic microinjection. Plasmids did not diffuse from the site of injection and plasmid–lissamine–NLS conjugates appeared to be progressively degraded in the cytoplasm. The process of plasmid DNA sequestration/degradation stressed in this study might be as important in limiting the efficiency of nonviral gene transfer as the generally recognized entry step of plasmid DNA from the cytoplasm into the nucleus
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007693805849
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  • 14
    Electronic Resource
    Electronic Resource
    Masthead (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999) 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330101
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  • 15
    Electronic Resource
    Electronic Resource
    Projektionsversuche mit dem Diaprojektor (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 45-50 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A variety of demonstration experiments can be shown to a large audience with a minimum amount of chemicals by using an ordinary slide projector and easily mounted cuvettes. A detailed instruction for assembling the cuvettes is given as m d l as examples for suitable demonstration experiments in general, inorganic, organic and physical chemistry.
    Additional Material: 21 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330106
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  • 16
    Electronic Resource
    Electronic Resource
    Wer und was ist es? (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 61-61 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330111
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  • 17
    Electronic Resource
    Electronic Resource
    Dokumentation (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 66-66 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330114
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  • 18
    Electronic Resource
    Electronic Resource
    Rückblick (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 67-67 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330117
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  • 19
    Electronic Resource
    Electronic Resource
    Masthead (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999) 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330201
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  • 20
    Electronic Resource
    Electronic Resource
    Umweltprobenbanken-eine wichtige Säule der Umweltbeobachtung (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 95-103 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Natural events as well as human activities are affecting the environment and even with largescale monitoring programs it is not possible to completely assess the state of the environment. But a documentation of the environmental status with respect to its chemical composition can be realized with systematically collected representative environmental samples, which can be stored for decades at very low temperatures almost without degradation. Such ‘banking activity’ allows a current environmental monitoring and also a retrospective analysis for the determination of components which have not been analyzed at the time of sampling because of ta lack in analytical techniques or because they have not been known or considered environmentally relevant. The concept of environmental specimen banking and general procedures are described. Various examples illustrate the many facets of such activities.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330205
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  • 21
    Electronic Resource
    Electronic Resource
    Jobsuch auf dem Internet (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 128-128 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Arbeitsmarktsituation in der Chemie hat sich in den letzten Jahren spürbar entspannt. Dennoch gibt es auf etlichen, nicht hundertprozentig dem Trend der Zeit entsprechenden Spezialgebieten immer noch einen beträchtlichen Überhang an Stellensuchenden. Entsprechende Mobilität vorausgesetzt, kann das Internet bei der Stellensuche hilfreich sein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330210
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  • 22
    Electronic Resource
    Electronic Resource
    Rückblick (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 135-135 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330215
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  • 23
    Electronic Resource
    Electronic Resource
    Masthead (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999) 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330301
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  • 24
    Electronic Resource
    Electronic Resource
    Quantenchemie auf dem Internet (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 165-166 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330306
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    Electronic Resource
    Electronic Resource
    Die Rolle des Aerosols im Klimasystem (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 158-164 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Atmospheric aerosol particles cause one of the largest uncertainties in estimates of human influence on climate - a good reason to take a closer look at the atmospheric life cycle of the aerosols and its effects. Besides a number of primary and secondary natural aerosol sources we need to consider since the beginning of industrialisation strong manmade particle sources. During its residence in the atmosphere the aerosol interacts in many physical and chemical ways with other atmospheric trace substances, most importantly with water vapor and its liquid and solid phases. Through its direct effect on solar and thermal radiation and through its influence on clouds the atmospheric aerosol exerts a climate forcing. To data we cannot predict the ensuing climate response because of our limited understanding of essential atmospheric processes and of the many possible feedbacks within the climate system. However, already our present knowledge of the role of the atmospheric aerosol in the climate system makes strictly global views of anthropogenic climate changes questionable.
    Notes: Der Stand unseres Wissens zum Kreislauf des Atmosphärischen Aerosols und von seiner Rolle im Klimasystem läßt sich wie folgt zusammenfassen: 1Unser Verständnis des globalen Aerosolkreislaufs und vor allem des menschlichen Eingriffs in denselben ist noch sehr unvollständig. Dies gilt in hohem Maße auch für die mit diesem Kreislauf verbundenen chemischen Mehrphasenprozesse.2Ein negativer direkter Klimaantrieb anthropogener Aerosole existiert über die Streuung und Absorption, hat aber noch große Unsicherheiten und kann über hoch mit Rußpartikeln belasteten Gebieten auch positive Werte annehmen.3Ein indirekter Klimaantrieb anthropogener Aerosole existiert wahrscheinlich und hat ebenfalls ein negatives Vorzeichen. Seine Größenordnung und Unsicherheiten lassen sich noch nicht quantifizieren.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330305
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  • 26
    Electronic Resource
    Electronic Resource
    Welche Bedeutung haben Theoretische Konzepte in der Chemie? (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 177-185 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Chemical concepts are important to gain a qualitative understanding of chemistry. They are needed to find interesting questions to which experimental research as well as quantum-chemical investigations and computer simulations can contribute. We point out why chemical concepts should be seen as an important and from fundamental physical theories to a certain degree independent part of chemistry. An overview and analysis of some concepts - which are often introduced only in connection with special examples instead of a discussion for their own sake - are given. We take a closer look at some concepts to illustrate our assertions. An analysis of the stability of the cyclic (MoNL3)-trimer demonstrates how these concepts work and what they can tell us about this special case.
    Notes: Wir haben versucht, deutlich zu machen, wie wichtig theoretische Konzepte in der Chemie sind. Dabei gelangen wir zu folgenden Schlußfolgerungen über die Konzepte, die in der Chemie herangezogen werden, um Beobachtungen zu deuten und zu verstehen: Qualitativ chemische Konzepte sind für ein Verständnis der Chemie unverzichtbar. Eine quantenchemische Berechnung liefert nicht automatisch Verständnis und Einordnung in einen Gesamtzusammenhang.Erst die vereinfachende Beschreibung chemischer Konzepte ermöglicht eine unmittelbare Diskussion chemischer Fragestellungen.Die Konzepte sind trotz grundlegender physikalischer Theorien bis zu einem gewissen Grade eigenständig.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330312
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  • 27
    Electronic Resource
    Electronic Resource
    Masthead (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999) 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330401
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  • 28
    Electronic Resource
    Electronic Resource
    Hundert Jahre Aspirin® (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 213-220 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The article commemorates the centenary of the protection of the proprietary mine of Aspirin. The early medicinal uses of salicylic acid derivatives in herbal remedies arc summarised as well as the biosynthesis of these derivatives. The history of the synthesis of salicylic acid and of acetyl salicylic acid (ASS) is described in detail as is the discovery of additional therapeutic applications and the basic pharmacology of ASS.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330406
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  • 29
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    Electronic Resource
    Internet-Werkzeuge für die Zusammenarbeit zwischen Chemikern (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 234-235 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330409
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  • 30
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    Alchemie. Lexikon einer hermetischen Wissenschaft. Herausgegeben von Claus Priesner und Karin Figala. Verlag C. H. Beck, München 1998. 412 S., 40 Abb., Leinen, DM 68,-. ISBN 3-406-44104-8 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 239-240 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330412
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  • 31
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    Electronic Resource
    Dokumentation (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 246-246 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330417
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  • 32
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    Electronic Resource
    Editorial (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 250-250 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330502
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  • 33
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    Electronic Resource
    ChiuZ aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 308-309 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330508
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    Electronic Resource
    Wer und was ist es? (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 312-312 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330511
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  • 35
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    Electronic Resource
    Impressum (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 314-314 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330514
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  • 36
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    Electronic Resource
    Literaturkarusell. Chemie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. IX 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330518
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    Editorial (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 318-318 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330602
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  • 38
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    Electronic Resource
    Chemische Biologie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 354-358 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Chemical Biology is a rapidly growing field at the interface of organic chemistry and cell biology. Chemical strategies are used to address biological questions not amenable to traditional genetic and biochemical techniques alone. Thc enormous potential of Chemical Biology is illustrated by four recent examples.
    Notes: Chemische Biologie ist eine junge Forschungsrichtung im Grenzgebiet zwischen Organischer Cherme und Zellbiologie, welche aus einem Bedarf nach neuen Techniken zur Untersuchung zellbiologischer Mechanismen entstanden ist. Chemische Methoden werden mit biochemischen und molekularbiologischen Methoden kombiniert, um neuartige Möglichkeiten für die biologische Grundlagenforschung zu schaffen. So werden synthetische Oligosaccharide kovalent an die Oberfläche lebender Zellen gebunden, die Konzentration von Calciumionen im Zytosol künstlich reguliert und Rezeptoren künstlich aktiviert.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330606
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  • 39
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    Electronic Resource
    Elektrosynthesen. Strom doppelt genutzt: Erste technische „Paired Electrosynthesis“ (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 373-374 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Eine neue Elektrosynthese erfüllt erstmals den Traum der Elektrochemiker, gleichzeitig Anoden- und Kathodenreaktion für organische Synthesen technisch zu nutzen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330610
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  • 40
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    Electronic Resource
    Experimente für die Chemie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 377-377 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330614
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  • 41
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    Electronic Resource
    Persistenz und Reichweite von Umweltchemikalien. Von M. Scheringer. Wiley-VCh, Weinheim 1999.XIII + 208 Abb.,17Tab., gebunden, DM 158,-.ISBN 3-527-29752-9 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 380-380 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330618
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  • 42
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    Electronic Resource
    Vorbereitungen für die Jahrtausend-Party (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 382-384 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Around the world, BASF has been preparing for Y2K since 1996. The Information services and the Process Control Technology divisions, as well as embedded systems and logistics, not to mention the company's customers and suppliers have all been systenmatically tested for Y2K capability. In addition, special precautionary measures in particular, at large Verbund sites - will be in place during the switchover period.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330621
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  • 43
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    Editorial (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 4-4 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330102
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  • 44
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    Electronic Resource
    Andere iu Z-Zeitschriften (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 66-66 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330115
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  • 45
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    Electronic Resource
    Gentechnik in der Schule (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 104-109 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The Fonds of German Chemical Industry (FCI) has produced an instrumental kit named „Blue Genes“ which enables High School teachers to perform in their school environment basic experiments of gene analysis and cloning. In particular, the kit contains all necessary equipment and reagents to perform a restriction analysis, and cloning and expression of a bacterial gene.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330206
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  • 46
    Electronic Resource
    Electronic Resource
    Chemie der Wunder (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 152-157 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: A few physical phenomena believed to be religious miracles are considered, and scientific explanations for them are proposed.
    Notes: Einige physikalische Phänomene, von denen man glaubte, sie seien religiöse Wunder, werden vorgestellt und wissenschaftliche Erklärungen hierfür vorgeschlagen.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330304
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  • 47
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    Electronic Resource
    Wer und was ist es? (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 173-173 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330308
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  • 48
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    Lebensgeschichten. Sternstunden der frühen Chemie von Johann Rudolph Glauber bis Justus von Liebig. Von Ernst F. Schwenk. Beck'sche Reihe 1252, Verlag C. H. Beck, München 1998. 288 S., 42 s/w-Abb., Paper-back, DM 19,80. ISBN 3-406-42052-4 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 176-176 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330311
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  • 49
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    Literaturkarusell. Interdisziplinäres (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. VIII 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330517
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    Literaturkarusell. Pharmazie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. XIV 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330520
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    Kupfer  -  Die biochemische Bedeutung eines Metalls (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 334-341 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The essential trace element copper plays a key role in living systems. Its metalloproteins are involved in various reactions. The IT ononuclear blue copper type-1 proteins take, part in electron transfer processes. Type-2 proteins can either act as oxidases, oxygenases, dioxygenases, or superoxide dismutases, containing one copper core. Dinuclear copper centers of Type-3 proteins are the oxygen transport system hemocyanin, oxidases and oxygenases. Due to this variety of functions copper deficiency and also abundance can cause severe damage of any life form.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330604
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    Fritz Haber, Carl Bosch und Friedrich Bergius  -  Protagonisten der Hochdrucksynthese (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 359-364 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: It is tried to fix the limits between the notions high pressure synthesis and high temperature chemistry. The work of Fritz Haber to apply high pressure to synthetise ammonia and of Friedrich Bergius to liquify coal to synthetise petrol is described. Special attention is given to the merits of Carl Bosch and his coworkers at BASF for applying the high pressure synthesis into industrial scale. The consequences of thc work of Haber, Bergius und Bosch on chemistry, social and political life and their importance for the present are considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330607
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    Bakterien, Viren, Prionen (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 376-376 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330613
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  • 54
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    Dokumentation (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 390-390 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330622
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  • 55
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    Von Biomineralien zu biomimetischen Materialien: Der Weg ist das Ziel (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 6-19 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Diatoms are unicellular organisms which possess a unique silicified cell wall. Their intricate structures have inspired the imagination of naturalists and scientists throughout centuries. However, molecular biological details about silica metabolic pathways still are obscure. To find out how soft matter can selforganize and create finite solid shapes and complex patterns is certainly one of the most challenging scientific problems today. Especially chemists just have started to unravel the mysteries of chemical morphogenesis.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330103
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    ChiuZ aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 58-60 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330108
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    Chemie im Selbststudium. Grundkurs Chemie I. Allgemeine und Anorganische Chemie. Von Arnold Arni. überarb. Aulf. 3., überarb. Aufl., WILEY-VCH, Weinheim 1998. XIV + 350 S., 66 Abb., 15 Tab., Broschur, DM 54,-. ISBN 3-527-29542-9. Grundkurs Chemie II. Organische Chemie. 2., überarb. Aufl. WILEY-VCH, Weinheim 1998. XIII + 198 S., 16 Abb., 5 Tab., Broschur, DM 48,-. ISBN 3-527-29562-3 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 60-61 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330110
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    Impressum (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 66-66 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330116
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    Editorial (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 70-70 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330202
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  • 60
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    Wissenschaft aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 122-125 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330208
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  • 61
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    Dokumentation (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 134-134 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330212
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  • 62
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    Impressum (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 134-134 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330214
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  • 63
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    Literaturkarusell. Chemie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. X 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330218
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  • 64
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    Editorial (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 138-138 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330302
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  • 65
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    ChiuZ aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 174-175 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330309
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  • 66
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    Chemie mit Licht. Photochemie. Von D. Wöhrle, M.W. Tausch und W.-D. Stohrer. WILEY-VCH, Weinheim 1998. XVI, 253, S., 169 Abb., 39 Tab., Broschur, DM 128,-.ISBN 3-527-29545-3 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 175-176 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330310
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  • 67
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    Editorial (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 190-190 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330402
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  • 68
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    Sandwich-artige Cyclopentadienylkomplexe von Hauptgruppenelementen (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 342-353 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Cyclopentadienyl (Cp) complexes of maingroup elements are classified and compared in terms of structural types, bonding features, and characteristic reactions. Halfsandwich, sandwich and multidecker sandwich arrangements of different type are observed including cluster species with weak or strong metal-metal bonds. The Cp-El bonding ranges from mainly covalent to purely ionic with important structure-determining intermolecular contacts in the latter. π-Complexation allows the stabilisation of compounds with low-valent elements such as AI(I), Ga(I), and Si(I1). Important reaction principles and applications are shortly described.
    Additional Material: 19 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330605
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  • 69
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    Wissenschaft aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 367-372 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330608
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  • 70
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    ChiuZ aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 375-375 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330612
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  • 71
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    Schreiben und publizieren in den naturwissenschaften. Vin H.F.Ebel u C. Bliefert. 4., völlig neu bearb. Aufl., WILEY-VCh, Weinheim 1988.XIV + 550 s., Broschur, Dm 68,-ISBN 3-527-29626-3 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 378-379 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330615
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  • 72
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    Wer war es? (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 381-381 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330620
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  • 73
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    Andere iu Z-Zeitschriften (1999)
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    Chemie in unserer Zeit 33 (1999), S. 390-390 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330623
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  • 74
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    Wissenschaft aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 53-58 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330107
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  • 75
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    Koffeinschub für Chemie-Applets im WWW (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 62-63 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330112
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  • 76
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    Wer war es? (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 129-129 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330211
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  • 77
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    Andere iu Z-Zeitschriften (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 134-134 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330213
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  • 78
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    Literaturkarusell. Biologie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. V 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330216
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  • 79
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    Literaturkarusell. Physik (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. VIII 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330217
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  • 80
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    Impressum (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 186-186 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330315
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  • 81
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    Methyltrioxorhenium (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 192-198 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330403
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  • 82
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    Molekulare Aspekte des Alterns (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 221-225 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In the last decade, major advances in the understanding of the biology of aging were made. Studies in worms, flies and yeast led to the identification of several life-extending genes. In mammals, two genes were found which, when mutated, shorten life span. Previous studies in rodents reporting life span prolongation by caloric restriction were confirmed and extended to lower organisms. The studies arc consistent with and supportive of the free radical theory of aging, which secs reactive oxygen species as the main contributor to aging. A refinement of this theory puts mitochondrial DNA into the center of the aging process. It appears that mitochondrial DNA may be both, a yardstick for the biological age and a signalling device to tell the organism when to die. A diet low in calories and high in antioxidants promises to lead to a better quality of life at old age and possibly to increased life span for humans.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330407
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    ChiuZ aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 237-239 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330411
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    Radikale und Radikalionen in der Organischen Synthese. Von Torsten Linker und Michael Schmittel. WILEY-VCH, Weinheim 1998. 421 S., DM 88,-. ISBN 3-527-29492-9 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 241-241 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330415
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    Impressum (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 247-247 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330419
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  • 86
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    Wiederaufladbare Batterien (1999)
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    Chemie in unserer Zeit 33 (1999), S. 252-266 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: This first part of „Rechargeable Batteries“ is devoted to materials and reactions in batteries with aqueous electrolytes. Lead-acid, nickelcadmium, nickel-metal hydride, and various zinc systems, such as zinc-manganese oxide, zinc-air, and zinc-bromine cells are discussed. Special attention is paid to the limited electrochemical stability window of the aqueous electrolytes, which enables overcharge and overdischarge protection of the battery but limits cell voltages to less than 2 Volts. In the following part of this article we will focus on nonaqueous electrolyte-based rechargeable batteries. Due to thc wider electrochemical stability window of these electrolytes high specific charge and high cell voltage batteries can be realized, e.g., the „4 V“ lithium ion cell.
    Additional Material: 19 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330503
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    Wissenschaft aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 304-308 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330507
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  • 88
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    Dokumentation (1999)
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    Chemie in unserer Zeit 33 (1999), S. 314-314 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330512
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    Chemie erlebt - 50 jahre GDCH. Hrsg. von der Gesellschaft Deutscher Chemiker. Das Buch ist im Eigenverlag erschienen und kann bei der Gesellschaft Deutscher Chemiker, Abteilung Öffentlichkeitsarbeit, Postfach 900440,60444 Frankfurt/M bestellt werde,304 S., Dm 39,-ISBN 3-924763-79-8 (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 379-380 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330616
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  • 90
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    Impressum (1999)
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    Chemie in unserer Zeit 33 (1999), S. 390-390 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330624
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  • 91
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    Feste Lösungen (1999)
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    Chemie in unserer Zeit 33 (1999), S. 33-44 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Solid solutions arc an area of inorganic chemistry that encompasses a wide variety of natural and synthetic compounds. This article is intended to be a selection of interesting examples which illustrate the importance of solid solutions in everyday life and industrial applications. A short discussion of the theoretical background is given, followed by the description of solid solutions of non-metals in metals such as steel. Furthermore, solid solutions with important optical (e.g. laser materials) and electrical properties (e.g. β-alumina) are discussed, referring to their chemical structure and technological relevance.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330105
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  • 92
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    ChiuZ aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 126-127 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330209
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  • 93
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    Primärprozesse der Photosynthese und ihre Modellierung (1999)
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    Chemie in unserer Zeit 33 (1999), S. 72-83 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Photosynthesis is one of the most fascinating fields of current interdisciplinary research. It seems miraculous that Nature, in the process of evolution, has managed to bring about a 100% quantum yield in charge separation occurring in the primary processes within the photosynthetic reaction centers. In fact, wasteful deactivation of the photoexcited electronic states into the ground state should be favoured and thus prevent charge separation. Biomimetic model compounds have been synthesized, essentially from porphyrins and quinones, resembling the redoxactive cofactors, Nature has developed. The underlying philosophy of this approach is to design and prepare suitable organic molecules allowing the specific properties of the complex electron transfer reactions to be tuned appropriately. Special emphasis is given the through comparison of structures and functions of native and artificial systems. The prominent electron transfer characteristics are discussed in particular by using time-resolved picosecond fluorescence and time-resolved EPR techniques.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330203
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    Literaturkarusell. Pharmazie (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. XI 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330219
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  • 95
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    Literaturkarusell. Inter-disziplinäres (1999)
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    Chemie in unserer Zeit 33 (1999), S. XIII 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330220
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  • 96
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    Biochemische Mechanismen einer einfachen Verhaltensreaktion (1999)
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    Chemie in unserer Zeit 33 (1999), S. 140-151 
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    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In active search for conditions for optimal phototrophic growth, halobacteria respond to light and to a variety of other environmental stimuli by taxis. Light reception is mediated by sensory rhodopsins, seven helix transmembrane retinal proteins that are stably complexed to specific MCP-related transducer proteins. Photoisomerization of the retinal chromophore generates a steric signal which activates the sensory rhodopsin-transducer-complex. Complex activation is relayed to a two component signaling system and transiently changes the cytoplasmic concentration of fumarate which, together with the small cytoplasmic protein CheY controls flagellar motor switching. Dual signaling by CheY and fumarate was also found in Escherichia coli where it mediates metabolic signaling and taxis in cells with disabled two-component system. Sensory integration of different environmental stimuli occurs at the level of the signaling domains of several stimulus-specific transducers constructed through combination of appropriate molecular modules. Irrespective of the complexity of the signaling network, the response to light is quantitatively predictable and stochastic. Its kinetic analysis suggests that time-dependent changes in the activity of signaling components can be resolved even in the context of a complex molecular network.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330303
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  • 97
    Electronic Resource
    Electronic Resource
    Wissenschaft aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 167-172 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330307
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  • 98
    Electronic Resource
    Electronic Resource
    Dokumentation (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 186-186 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330313
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  • 99
    Electronic Resource
    Electronic Resource
    Rückblick (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 187-187 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330316
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  • 100
    Electronic Resource
    Electronic Resource
    Wissenschaft aktuell (1999)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 33 (1999), S. 228-233 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19990330408
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