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Alopecia induced in young mice by exposure to excess dietary zinc (1986)

Mulhern, S. A. ; Stroube, W. B. ; Jacobs, R. M.

Springer

Cellular and molecular life sciences 42 (1986), S. 551-553

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ISSN: 1420-9071

Keywords: Alopecia ; zinc excess ; mice ; copper deficiency

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Second generation mice were exposed to normal (50 ppm, Group I) or excess (2000 ppm, Group II) zinc in the maternal diet during gestation and lactation, then weaned and continued on the mother's diet until sacrifice at 8 weeks. Tibia zinc reflected dietary intake. Group II had reduced plasma copper, body weight, and hematocrit; the second coat of hair appeared late and was lighter in color than Group I, possibly as an effect of copper and pigmentation development and hair growth.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01946698

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