ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The β-oxide ring of 3-alkyl-3-(N-morpholinomethyl)oxacyclobutanes is opened to give methiodides or hydrohalide salts, respectively, of 2-alkyl-2-(N-morpholinomethyl)-3-halopropanol when they are heated with methyl iodide in methanol under pressure or heated with hydrohalic acids. When two morpholinomethyl groups are present in the 3 position of the oxacyclobutane ring, it is not opened.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00470150