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Transformed steroids (1976)

Voishvillo, N. E. ; Kamernitskii, A. V. ; Khaikova, A. Ya. ; [et al.]

Springer

Russian chemical bulletin 25 (1976), S. 1303-1305

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ISSN: 1573-9171

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology

Notes: Conclusions 1. It was shown that it is theoretically possible to transform Δ5-3β-hydroxy-, Δ5-3β-acetoxy-, and Δ4-3-ketosteroids to Δ1,4-3-ketosteroids employing the immobilized cells of various species of bacteria. 2. The immobilization of the bacterial cells in polyacrylamide gel reduces the rate of the complete cleavage of the steroids and in this way increases the yield of the 1,2-dehydro compounds. 3. The Δ1,4-3-ketosteroids were obtained in 68–85% yield by employing the immobilized cells ofMycobacterium globiforme 193.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00928076

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