ISSN:
1573-2568
Keywords:
ELECTROGASTROGRAPHY
;
FUNCTIONAL DYSPEPSIA
;
GASTROINTESTINAL MOTILITY
;
GASTRIC EMPTYING
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The aim of this study was to investigateabnormalities in pediatric patients with functionaldyspepsia. Fifteen symptomatic pediatric patientsdiagnosed with functional dyspepsia and 17 aged-matchedhealthy controls were studied. Gastric myoelectricalactivity was recorded using surface electrogastrographyfor 1 hr in the fasting state and 1 hr after a testmeal. It was found that, in comparison with thecontrols, the children with functional dyspepsia had alower percentage of 2- to 4-cpm slow waves in bothfasting state (66.0 ± 4.7% vs 79.7 ± 3.1%,P 〈 0.07) and fed state (72.4 ± 5.4% vs 85.0± 2.9%, P 〈 0.04), and a significantly higherinstability of the dominant frequency in both fastingstate (0.50 ± 0.05 vs 0.31 ± 0.04, P 〈0.01) and fed state (0.39 ± 0.05 vs 0.25 ±0.03, P 〈 0.05). It was also found the postprandial increase inEGG dominant power in the patients was inverselycorrelated with the total symptom score (r = 0.63, P =0.03). It was concluded that abnormal gastricmyoelectrical activity may play a role in the pathogenesis ofpediatric functional dyspepsia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1026661627304
