ISSN:
1432-1440
Keywords:
Omega-3-fatty acids
;
PUFA
;
Nucleation time
;
Cholesterol saturation index
;
Diet
;
Polyunsaturated fatty acids
;
Biliary lipids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The daily administration of fish oil, containing 1.5 g omega-3-fatty acids causes a significant decrease in nucleation time (12.1 ±7.3 vs. 2.0 ±1.2 days, p〈 0.001), as well as in biliary cholesterol saturation and biliary cholesterol composition in 13 healthy subjects. The nucleation time, cholesterol saturation index and biliary lipids showed no significant differences in 11 cholesterol gallstone patients after a six-week treatment period with omega-3-fatty acids. Taurocholate percentage increased significantly in the gallstone group (10.4 ±3.9 vs 13.5 ±1.7%, p〈0.05). The levels of the other bile acids remained unchanged during the treatment period. Therefore, the incidence of gallstones might be increased after treatment with fish oil, containing omega-3-fatty acids.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01644757
